Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7601848 | Multifunctional reagent for the synthesis of thiol modified oligomers The invention relates to compounds of formula (I), wherein Z represents a hydrocarbon with 2 to 28 C atoms, wherein Z can also comprise elements N, O, P, S, Si and halogen as heteroatoms, R1 and R2 are identical or different sulfur protecting g... | 10/13/2009 |
| 7385067 | Process for the preparation of compounds having a CFO bridge The invention relates to a process for the preparation of compounds containing at least one —CF2—O— bridge in the molecule, in which a) an acid is added onto at least one ketene dithioketal, b) the... | 06/10/2008 |
| 7371777 | Cyclic compound and PPAR agonist The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. ... | 05/13/2008 |
| 7348441 | Methyl 2,4,9-trithiaadamantane-7-carboxylate Methyl 2,4,9-trithiaadamantane-7-carboxylate and a method for its manufacture is disclosed. The method reacts oxidized methyl triallyl acetate with a Lewis acid and a sulphuring agent. ... | 03/25/2008 |
| 7301705 | Alicyclic compound for optical material The alicyclic compound of the present invention has a five- or more membered ring structure having an epithioethylene linkage and/or an epidithioethylene linkage, and has tow or more sulfur atoms in its molecule. Optical materials produced by curing the alicyclic co... | 11/27/2007 |
| 7091344 | Infrared chromophores An infrared dye, characterized in that the dye comprises of Formulae 1 to 5 ... | 08/15/2006 |
| 6995276 | Cyclic disulfide compound, process of producing the same and optical product comprising the same A compound capable of giving optical materials that may be high in both refractive index and Abbe's number and may be excellent in heat resistance and transparency, and a process that may produce the same with good efficiency are disclosed. The compound may be a cyc... | 02/07/2006 |
| 6900338 | Scavenger compounds The present invention provides novel compounds having scavenging and anti-ROS properties and pharmaceutical composition comprising these compounds for treatment of conditions associated with oxidative stress or free radical injury. The compounds of the invention are... | 05/31/2005 |
| 6875894 | Bis(alkylthio)carbenium salts The invention relates to bis(alkylthio)carbenium salts of the formula I with the stated definitions for R1, R2, R3 and Y−, and to a process for the preparation th... | 04/05/2005 |
| 6787062 | Producing liquid crystals with CF2O bond The invention relates to a process for the preparation of compounds having at least one —CF2O— bridge in the molecule, which comprises initially reacting a bis(alkylthio)carbenium salt with a compound containing at least one hydroxyl group in the pres... | 09/07/2004 |
| 6664287 | Antioxidants This invention comprises administering to a human or animal in need of treatment an effective amount of an antioxidant lipoic acid derivative and/or pharmaceutically acceptable salts and solvates thereof for the treatment or prevention of pathological (in... | 12/16/2003 |
| 6566521 | Valeraldehyde and process for its preparation Bidentate phosphine ligands of the formula ##STR1## wherein the substituents are as defined in the specification and a process for preparing linear aldehydes by hydroformylating internal olefins using such phosphine ligands.... | 05/20/2003 |
| 6562861 | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors ##STR1## Compounds I-III wherein U is CH, O, or S; Z is mono- or di-substituted carbon; R is (CH2)nCO2H, (CH2)nSO3H, (CH2)nPO3H2, (CH2)nNO2, CH(SCH3)3, esters; R1 is H, hydroxyalkyl, aminoalkyl, alkoxyalkyl; RR1 is O; n is 0-4; R2, R3 is H, hydroxyalkyl, ... | 05/13/2003 |
| 6534545 | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and cosmetics 6-tert-Butyl-1,1-dimethylindane derivatives which are unsaturated in the 4-position of formula: ##STR1## X represents: (i) either a radical of formula: (a) ##STR2## and Y represents a radical of formula: (b) ##STR3## (ii) or a radical of formula: (c... | 03/18/2003 |
| 6458908 | Sulfur-containing unsaturated carboxylate compound and its cured products A sulfur-containing unsaturated carboxylate compound comprising a sulfur-containing substituent and at least two ,ଲ-unsaturated carboxylic acid residues, which are each attached to a secondary or tertiary carbon atom via an oxygen atom; a pol... | 10/01/2002 |
| 6379590 | Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se... | 04/30/2002 |
| 6344556 | Polymerisable monomers and polymers The invention relates to compounds of the formulae: ##STR1## processes for their preparation, polymers, co-polymers or block co-polymers containing them or their use as monomers or co-monomers in free radical polymerisation and in the manufacture of adhes... | 02/05/2002 |
| 6071861 | Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production The dihalopropene compounds of the general formula [I ] have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks.... | 06/06/2000 |
| 6043361 | Polymerisable monomers and polymers The invention relates to compounds of the formulae: processes for their preparation, polymers, co-polymers or block co-polymers containing them or their use as monomers or co-monomers in free radical polymerisation and in the manufacture of adhesives, den... | 03/28/2000 |
| 6022895 | Substituted amino compounds and their use as substances having an analgesic effect Substituted amino compounds of general formula (I) ##STR1## are described, as are a method of preparing them and their use as drugs, especially as analgesics.... | 02/08/2000 |
| 5718845 | Tricyanovinyl substitution process for NLO polymers Nonlinear optical compounds which contain a heteroaromatic ring and may further comprise a tricyanovinyl group attached to the heteroaromatic ring.... | 02/17/1998 |
| 5698580 | Antiviral agent containing benzodithiin derivative as active ingredient Antiviral agents comprising, as an active ingredient, a 1,4-dihydro-2,3-benzodithiin derivative of the formula ##STR1## wherein each symbol is as defined in the Specification, or a pharmacologically acceptable salt thereof. The antiviral agents of th... | 12/16/1997 |
| 5668168 | 1,2-dithiin antiinfective agents This invention pertains to a novel group of 1,2-dithiin compounds useful as antiinfective agents, and a novel synthetic process to produce the same. The compounds are particularly effective in treating fungal infections, especially those caused by Candida... | 09/16/1997 |
| 5650098 | Substituted naphthopyrans Described are novel reversible photochromic 2H-naphtho[1,2-b]pyran compounds, examples of which are compounds having certain substituents at the 5 and 6-positions of the naphtho portion of the naphthopyran and at the 2-position of the pyran ring, e.g., 2,... | 07/22/1997 |
| 5621108 | Processes and intermediates for preparing macrocycles Novel processes for the preparation of lactam- and lactone-containing macrocyles are provided. In preferred embodiments, rapamycin and demethoxyrapamycin are prepared by a convergent synthesis regime. Intermediates useful in the synthetic processes are al... | 04/15/1997 |
| 5583235 | Preparation of symmetrical and unsymmetrical 3,6-disubstituted-1,2-dithiins having antifungal activity The present invention provides an improved procedure for the preparation of 3,6-disubstituted-1,2-dithiin derivatives, especially unsymmetrical 1,2-dithiins. In addition, the process offers significant process, scaleup, and safety advantages over the prev... | 12/10/1996 |
| 5580897 | 1,2-dithiins having antifungal activity Novel 1,2-dithiin compounds useful as antifungal or anti-infective agents, as well as methods for their use as such, are described. The 1,2-dithiin compounds are particularly effective in treating infections, especially those caused by Candida albicans, C... | 12/03/1996 |
| 5556875 | 1,2-dithiin antiinfective agents This invention pertains to a novel group of 1,2-dithiin compounds useful as antiinfective agents, and a novel synthetic process to produce the same. The compounds are particularly effective in treating fungal infections, especially those caused by Candida... | 09/17/1996 |
| 5502073 | Heterocyclic pesticidal compounds Compounds of the formula (I) ##STR1## which contain between 10 and 27 carbon atoms, and wherein m and n are independently selected from 0, 1 and 2; R2a is hydrogen, methyl, or ethyl; R2b is acetylene or contains between 3 and 18... | 03/26/1996 |
| 5436361 | Process for synthesizing enediynes A process for synthesizing enediynes is provided. Specifically, the formed enediynes contain a hex-3-ene-1,5-diynyl group. Production of the enediynes involves adding a base to a propargylic halide in the presence of a chelating agent, which causes a carb... | 07/25/1995 |
| 5405968 | Polyketomethine dyes Methine dyes with a polyketo group I ##STR1## where A is ##STR2## R1 is a 5- or 6-membered cycloaliphatic radical which contains one or two hetero atoms from the group --NR4 --, --O-- and --S-- and which may be fused t... | 04/11/1995 |
| 5296505 | Compositions of retinoids substituted with a dithiane ring, their use, and process for preparing the compounds The invention relates to a stereospecific derivative of formula: ##STR1## in which R is hydrogen or a C1 -C4 thioalkyl. The invention also relates to the use of these compounds for the manufacture of stereospecific retinal or re... | 03/22/1994 |
| 5283355 | Benzoquinone compounds Compounds of the Formula (5) and processes for their preparation and use, particularly in the manufacture of unsymmetrical triphenodioxazine dyes: ##STR1## wherein: Y is H, alkyl, substituted alkyl, alkoxy, Cl or Br; R is a group of Formula (3) ##STR... | 02/01/1994 |
| 5202348 | Thiarubrine antifungal agents This invention pertains to a novel group of Thiarubrine substances and closely related derivatives, useful as antifungal and antibiotic agents.... | 04/13/1993 |
| 5086187 | Herbicidal pyrones Compounds of the general formula, including isomers and tautomers thereof: ##STR1## wherein: R1 to R5 are as defined in the text; the compounds have herbicidal and plant growth regulating properties; including compositions conta... | 02/04/1992 |
| 4985411 | Dialkyl-substituted dithianes and pesticidal compositions The present invention provides compounds of the formula (I): ##STR1## wherein m and n are independently selected from 0, 1 or 2, ##STR2## R is selected from hydrogen, methyl or ethyl; R1 is selected from C1-4 hydrocarbyl su... | 01/15/1991 |
| 4975457 | Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis Certain trans-2,3-disubstituted-2,3-dihydro-5-hydroxybenzofurans are described. The synthesis involves an intramolecular Michael addition to yield the thermodynamic trans isomer. The compounds were found to be inhibitors of 5-lipoxygenase, an enzyme cruci... | 12/04/1990 |
| 4946861 | 1,3-dithian-2-ylidenes, their oxides, pharmaceutical compositions, and methods of use thereof The invention relates to the use of ketenethioacetals of the formula ##STR1## in which R1 represents aryl or heteroaryl, R2 represents hydrogen, an optionally substituted hydrocarbon radical, heteroaryl, an acyl radical, a group... | 08/07/1990 |
| 4927845 | Compounds of the anthraquinone series Anthralin analogues containing a thio-substituent, especially in one or more of the positions 2-, 7- and 10- of the anthralin ring. They may be made by reacting an anthralin derivative (e.g. 10-bromoanthralin) with a thiol or a compound containing a group... | 05/22/1990 |
| 4898986 | Inosose derivatives, production and use thereof Disclosed is a novel inosose compound represented by the general formula: ##STR1## wherein X1 and X2 are both halogen; X1 is hydrogen and X2 is halogen; or X1 is --SQ1 and X2 is ... | 02/06/1990 |
