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| Number | Title | Issue Date |
| 7301705 | Alicyclic compound for optical material The alicyclic compound of the present invention has a five- or more membered ring structure having an epithioethylene linkage and/or an epidithioethylene linkage, and has tow or more sulfur atoms in its molecule. Optical materials produced by curing the alicyclic co... | 11/27/2007 |
| 7268148 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes Acne-affected skin has been found to be accompanied by the presence of matrix-degrading enzymes such as MMPs and neutrophil elastase, induction of neutrophils, and a reduction in procollagen biosynthesis. This invention treats scarring and inflammation accompanying ... | 09/11/2007 |
| 7166726 | Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity Disclosed herein are compounds of the formula wherein R1 is independently H or alkyl of 1 to 6 carbons; R2 is optional and is defined as lower alkyl of 1 to 6 carbons, F, Cl, Br... | 01/23/2007 |
| 7101998 | Fused ring compounds, and their use as cationic photoinitiators Compounds of formula (I): [in which: R1 represents a direct bond, an oxygen atom, a group >CH2, a sulphur atom, a group >C═O, a group —(CH2)2— or a group of formu... | 09/05/2006 |
| 7097995 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes A chemiluminescent substrate of a hydrolytic enzyme having the following general Formula I is disclosed, as follows: Lumi-M-PFormula I where “Lumi” is a chemiluminescent moiety capable of producing light (a) by itself, (b) with MP attached an... | 08/29/2006 |
| 6881867 | Method for hydroformylation, xanthene-bridged ligands and catalyst comprising a complex of said ligands In a process for the hydroformylation of ethylenically unsaturated compounds, at least one complex of a metal of transition group VIII. with at least one phosphorus-, arsenic- or antimony-containing compound as ligand is used as hydroformylation catalyst, where the ... | 04/19/2005 |
| 6730697 | Dihydrothiaphenanthrenecarbonylguanidines: composition, process of making, and use as medicament or diagnostic aid Dihydrothiaphenanthrenecarbonylguanidine compound of formula I These compounds are potentially suitable as antiarrythmic medicaments with a cardioprotective component for prophylaxis of an infarction and treatment of inf... | 05/04/2004 |
| 6602903 | Substituted heterocyclic compounds The invention relates to compounds of formula (I): ##STR1## and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.... | 08/05/2003 |
| 6576595 | Xanthone derivatives, processes for their preparation and their use for controlling harmful fungi, and compositions comprising these derivatives Xanthone derivatives of the formula I ##STR1## where the index and the variables are as defined below: n is 0, 1 or 2; R1 is alkyl or haloalkyl; R2,R3 are alkoxy, alkenyloxy or alkynyloxy, or R2 and R3 tog... | 06/10/2003 |
| 6528601 | Polymerizable sulfur-containing (meth) acrylate, polymerizable composition and optical lens There is disclosed a polymerizable sulfur-containing (meth)acrylate, it has a high refractive index, a great Abbe's number and excellent light resistance and is suitable for the production of a transparent resin which rarely smells at the time of molding ... | 03/04/2003 |
| 6521769 | Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include chiral C1-C6 TunaPhos ligands. The ruthenium TunaPhos complex reduces ketones to the corresponding alcohols... | 02/18/2003 |
| 6444623 | Methods for the production of sulfurized diphenyloxides and compositions made therefrom The present invention relates to methods for production of sulfurized diphenyloxides wherein a diphenyloxide is reacted with elemental sulfur in the presence of solid acid catalyst. The solid acid catalyst can be a zeolite or a catalytic amount of a Fried... | 09/03/2002 |
| 6384045 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxypyrone synthetic method is a simple con... | 05/07/2002 |
| 6346615 | Chemiluminescent 1,2-dioxetanes Spiroadamantyl dioxetanes bearing an alkoxy substituent, and an aromatic substituent of phenyl or naphthyl on the dioxetane ring can be activated to chemiluminesce if the aromatic substituent bears a moiety designated OX, wherein the X is cleaved by an en... | 02/12/2002 |
| 6288234 | Multibinding inhibitors of microsomal triglyceride transferase protein Disclosed are multibinding compounds which inhibit microsomal triglyceride transferase protein (MTP), a protein which mediates the transfer of lipids during the assembly of lipoproteins and related biomolecules. The multibinding compounds contain from 2 t... | 09/11/2001 |
| 6132956 | Chemiluminescent 1,2-dioxetanes Dioxetanes that can be triggered by bases are provided which can be used to detect bases in organic solvents, aqueous preparations and detect gaseous bases in the atmosphere. The dioxetanes can be used to detect the release of bases from various labels, a... | 10/17/2000 |
| 6117869 | Compounds for and methods of inhibiting matrix metalloproteinases The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds ##STR1## More particularly, the present invention relates to a method of treati... | 09/12/2000 |
| 6110961 | Phenoxathin derivatives as inhibitors of monoamine oxidase The present invention provide phenoxathiin compounds useful in the prophylaxis and treatment of mental disorders, such as depression. The present invention also provides a method for treating a mammal having depression, anxiety or other conditions respons... | 08/29/2000 |
| 5958970 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxyprone synthetic method is a simple cond... | 09/28/1999 |
| 5885936 | Heterotricyclic herbicides Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful for controlling undesired vegetation ##STR1## wherein Q, X, A, B, R1 through R3, m, p, q, r, and s are as defined in th... | 03/23/1999 |
| 5844024 | Cyclic diphenylacetonitriles as stabilizers Compounds of the formula I ##STR1## in which the general symbols are as defined in claim 1, as stabilizers for organic materials against thermal, oxidative or light-induced degradation are described.... | 12/01/1998 |
| 5817835 | Benzothioxepanone and benzothioxepane thione compounds Novel benzothioxepanone and benzothioxepane thione compounds are characterized by the formula ##STR1## wherein Z is: ##STR2## R is Cl, Br, F, C1 to C8 alkyl, or C1 to C8 alkoxy; X and Y are each h... | 10/06/1998 |
| 5811389 | Tri- and tetracyclic compounds There are described compounds of the formula ##STR1## Wherein the variables have been defined herein. The compounds are useful as research tools in the determination of biologically active peptides sequences and also potentially suitable as medicamen... | 09/22/1998 |
| 5807884 | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases A method for the treatment of cardiovascular diseases and noncardiovascular inflammatory diseases that are mediated by VCAM-1 is provided that includes the removal, decrease in the concentration of, or prevention of the formation of oxidized polyunsaturat... | 09/15/1998 |
| 5750351 | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases A method for the treatment of cardiovascular diseases and noncardiovascular inflammatory diseases that are mediated by VCAM-1 is provided that includes the removal, decrease in the concentration of, or prevention of the formation of oxidized polyunsaturat... | 05/12/1998 |
| 5728846 | Benzo1,2-g!-chrom-3-ene and benzo1,2-g!-thiochrom-3-ene derivatives Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinoid antagonist and/or retinoid inverse-agonist-like biological activity.... | 03/17/1998 |
| 5591848 | Spiroconjugated charge-transfer dyes for optical applications New intramolecular charge-transfer organic dyes are described. The design of these molecules is based on the phenomenon of spiroconjugation, and it provides a modular approach to the preparation of unique materials with interesting optical properties. In ... | 01/07/1997 |
| 5569640 | Substituted 1,3-benzadioxane-4-ones and 1,3-benzathioxane-4-ones, their preparation and their conversion to crop protection agents Cyclic acetals of the formula I ##STR1## where the substituents have the following meanings: R1 and R2 are hydrogen, unsubstituted or substituted alkyl or phenyl; additionally R1 and R2 together are an unsu... | 10/29/1996 |
| 5543295 | Chemiluminescent 3--(Substituted adamant--2'--Ylidene) 1,2--Dioxetanes Enzymatically clearable chemiluminescent 1,2-dioxetane compounds capable of producing light energy when decomposed, substantially stable at room temperature before a bond by which an enzymatically clearable labile substituent thereof is intentionally clea... | 08/06/1996 |
| 5420156 | Pharmacologically active compound and use 1-Ethylphenoxathiin 10,10-dioxide (I) ##STR1## inhibits monoamine oxidase-A and is useful in the treatment of disorders such as depression.... | 05/30/1995 |
| 5347040 | Sensitized onium salts Onium salt capable of generating acid upon exposure to actinic radiation having the following structure: (R1)a (R2)b (R3)c Q+ --A--M+ X- --B--X'- wher... | 09/13/1994 |
| 5326882 | Chemiluminescent 3-(substituted Adamant-2'-Ylidene) 1,2-dioxetanes Enzymatically cleavable chemiluminescent 1,2-dioxetane compounds capable of producing light energy when decomposed, substantially stable at room temperature before a bond by which an enzymatically cleavable labile substituent thereof is intentionally clea... | 07/05/1994 |
| 5286396 | Alkylated phenoxathin base stock for lubricants Monoalkylated phenoxathins are high-temperature stable lubricant fluids having extreme pressure and antiwear properties, additive solubility and inherent EP/antiwear properties. These novel phenoxathin fluids may also be used as additives in other lubrica... | 02/15/1994 |
| 5220034 | Protected derivatives of the enone of spectinomycin Process for alkylating protected spectinomycin enone derivatives in the gamma position in order to produce intermediates useful in the synthesis of 6'alkylspectinomycins. The intermediate have the formula ##STR1## which comprises reacting a compound ... | 06/15/1993 |
| 5208332 | Optical probe for the cytochrome P-450 cholesterol side chain cleavage enzyme An optical probe enables the study of enzyme activity by absorbance spectroscopy or by sensitive fluorescence methods. In particular, the probe provides the ability to monitor the activity of cytochrome P-450scc enzyme, the rate limiting enzyme... | 05/04/1993 |
| 5179092 | Compound effective as cerebral insufficiency improver A compound having the formula (I): ##STR1## wherein A is --CH2 --, --O--, or --S--; R1 is CH3 or OCH3 ; R2 is hydroxy or carboxy which may be optionally esterized or amidated; R3 is H ... | 01/12/1993 |
| 5066795 | Perfluoroalkyl-containing compound A (perfluoroalkyl)dibenzonium salt represented by the following general formula ##STR1## wherein Rf represents a perfluoroalkyl group having 1 to 10 carbon atoms, A represents a sulfur of selenium atom, R1 and R2, ... | 11/19/1991 |
| 5047554 | 3-substituted-2-oxindole derivatives This invention relates to novel 3-substituted-2-oxindole derivatives which are inhibitors of prostaglandin H2 synthase, 5-lipoxygenase and interleukin-1 biosynthesis. The compounds of the invention are useful as inhibitors of prostaglandin H | 09/10/1991 |
| 5036067 | Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase Compounds having the formula I: ##STR1## are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, ... | 07/30/1991 |
| 5011967 | Method for preparing aromatic bischloroformate compositions Bischloroformate oligomer compositions are prepared by passing phosgene into a heterogeneous aqueous-organic mixture containing at least one dihydroxyaromatic compound, with simultaneous introduction of a base at a rate to maintain a specific pH range and... | 04/30/1991 |
