"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
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| Number | Title | Issue Date |
| 7612217 | Sulfonium compound The present invention provides a sulfonium compound represented by the formula (I): wherein Q1 and Q2 each independently represent a fluorine atom or a C1-C6 perfluoroalkyl group, and A+ rep... | 11/03/2009 |
| 7576223 | Chemical amplification type resist composition The present invention provides a sulfonium salt of the formula (Ia) a polymeric compound comprising a structural unit of the formula (Ib) and a chemical amplification type positiv... | 08/18/2009 |
| 7420002 | Amino acid conjugates providing for sustained systemic concentrations of GABA analogues Compounds that provide for sustained systemic concentrations of GABA analogs following oral administration to animals are disclosed. Pharmaceutical compositions including, and methods using, such compounds are also disclosed. ... | 09/02/2008 |
| 7371503 | Sulfonium salt compound, photoacid generator, and positive-tone radiation-sensitive resin composition A sulfonium salt compound excelling in transparency to deep ultraviolet rays at a wavelength of 220 nm or less, exhibiting well-balanced excellent performance such as sensitivity, resolution, pattern form, LER, and storage stability when used as a photoacid generato... | 05/13/2008 |
| 7371777 | Cyclic compound and PPAR agonist The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. ... | 05/13/2008 |
| 7332519 | Spirocyclic cyclohexane compounds Spirocyclic cyclohexane compounds, methods for their production, pharmaceutical compositions containing these compounds, and the use of these spirocyclic cyclohexane compounds for treating conditions associated with the nociceptin/ORL1 receptor system, e.g. pain, dr... | 02/19/2008 |
| 7317125 | Diacylglycerol acyltransferase inhibitors Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutica... | 01/08/2008 |
| 7301705 | Alicyclic compound for optical material The alicyclic compound of the present invention has a five- or more membered ring structure having an epithioethylene linkage and/or an epidithioethylene linkage, and has tow or more sulfur atoms in its molecule. Optical materials produced by curing the alicyclic co... | 11/27/2007 |
| 7288560 | Spirocyclic cyclohexane derivatives The present invention relates to spirocyclic cyclohexane compounds, to methods for their production, to pharmaceutical compositions containing these compounds, to methods of treatment using such compounds and to the use of such spirocyclic cyclohexarie compounds for... | 10/30/2007 |
| 7253940 | Nanoporous and nanocrystalline film and electrochromic device A nanoporous, nanocrystalline film and electrochromic device. The nanoporous, nanocrystalline film has a conducting metal oxide having an electroactive compound, which is either a p-type or n-type redox promoter or p-type or n-type redox chromophore, absorbed theret... | 08/07/2007 |
| 7208169 | Biphenyl carboxamides The invention relates to novel biphenylcarboxamides of the formula (I) in which R1, R2, m, n, R3, Y and A are as defined in the disclosure, to a plurality... | 04/24/2007 |
| 7188031 | Method for acquiring information of a biochip using time of flight secondary ion mass spectrometry and an apparatus for acquiring information for the application thereof A measurement method is provided, which enables to obtain a two-dimensional image with better quantitative-ability by suppressing the influence of the charge-up, when the two-dimensional secondary ion image is obtained for a biological material fixed on a substrate ... | 03/06/2007 |
| 7169774 | Cephalotaxane derivatives and their processes of preparation and purification The present invention concerns a new general process for asymmetric hemisynthesis of harringtonines and their analogs, that are alkaloids used in chemotherapy. This process comprises direct esterification of a natural cephalotaxine with an acylating compound constit... | 01/30/2007 |
| 7166726 | Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity Disclosed herein are compounds of the formula wherein R1 is independently H or alkyl of 1 to 6 carbons; R2 is optional and is defined as lower alkyl of 1 to 6 carbons, F, Cl, Br... | 01/23/2007 |
| 7148223 | 4′-thio-L-xylo furanosyl nucleosides, precursors thereof, preparation and use thereof Compounds represented by the formula 1: A is selected from the group consisting of wherein each R individually is H or... | 12/12/2006 |
| 7112683 | Cyclic sulfone containing retroviral protease inhibitors The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease. ... | 09/26/2006 |
| 7109211 | Substituted benzopyran derivatives for the treatment of inflammation A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I′ wherein X, A1, A2, A | 09/19/2006 |
| 7087787 | Method for producing derivatives of 4-alkylsulfinyl methylarylene methanols The invention relates to a method for producing derivatives of 4-alkylsulfinyl methylarylene methanols. Derivatives of 4-alkylsulfinyl methylarylene methanols are valuable monomers in the production of conjugated polymers, which are suitable for use as electrolumine... | 08/08/2006 |
| 7081279 | Alkenyl compound having a negative Δε value, liquid crystal composition, and liquid crystal display device Liquid crystalline compounds having a large negative Δε low viscosity, a large K33/K11 value, a small Δε/Δ⊥ and mutually excellent solubility even at low temperature, compositions containing at least one of the compounds and liquid cryst... | 07/25/2006 |
| 7074743 | Herbicidal composition comprising 4-iodo-2-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)ureidosulfonyl]benzoic esters Herbicidal compositions comprising A) at least one compound from the group of the substituted phenylsulfonylureas of the formula I and their agriculturally acceptable salts in which ... | 07/11/2006 |
| 7060425 | Color photographic material A color photographic material is described containing a compound of formula (I) wherein, if n=1, R1 is, inter alia, a radical of formula (II), and, if n=2, R1 is unsubstituted or C1–C4alkyl- or hydroxy-substituted phenyl... | 06/13/2006 |
| 7033727 | Photosensitive composition and acid generator A photosensitive composition of the present invention has excellent sensitivity and pattern profile, which comprises an acid generator having a specific structure. ... | 04/25/2006 |
| 7034188 | Production method of ketone compound A method for producing a ketone, particularly a macrocyclic ketone, from a 2-hydroxycycloalkanone having from 12 to 18 carbon atoms by efficiently dehydrating and reducing the acyloin in a single reaction vessel. A method for producing a ketone compound, which compr... | 04/25/2006 |
| 7015328 | Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof The present invention is directed to substituted coumarins and quinolines and analogs thereof, represented by the general Formula I: wherein A, B, X, Y, and Z are defined herein. The present invention also relates to t... | 03/21/2006 |
| 6992101 | N-(indole-2-carbonyl) and H-thieno[2,3-b]pyrrole-5-carboxamide anti-diabetic agents The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R′, R″, R′″, and Z are as defined herein; pharmaceut... | 01/31/2006 |
| 6989453 | Method of producing a cyclohexenone oxime ether lithium salt, products which can be obtained using this method, the use thereof and corresponding plant protection agents A process for preparing 2-{1-[2-(4-chlorophenoxy)propoxyimino]-butyl}-3-hydroxy-5-(tetrahydrothiopyran-3-yl)cyclohex-2-enone lithium salt by reacting the corresponding acid 2-{1-[2-(4-chlorophenoxy)-propoxyimino]butyl}-3-hydroxy-5-(tetrahydrothiopyran-3-yl)-cyclohex... | 01/24/2006 |
| 6942980 | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities Methods of characterizing and identifying negative hormones of nuclear receptors. Also disclosed are methods of making modulators of retinoid nuclear receptor transactivation activity, assays for agonists, antagonists, and negative hormones of the RAR receptor, and ... | 09/13/2005 |
| 6939007 | Photochromic bis-naphthopyran compounds and methods for their manufacture The invention provides photochromic bis-naphthopyran compounds as well as methods for their manufacture and their use. The bis-naphthopyran compounds of the invention exhibit a wide range of color, i.e., from pink to purple to blue gray, upon activation by a source ... | 09/06/2005 |
| 6930200 | Multicomponent synthesis of amino acids and derivatives thereof Mono-substituted and di-substituted alpha-amino acids and derivatives thereof, substituted at the alpha positon with one (mono-) or two (di-) substituents (R2 and/or R3) as shown in Formula 1: N(R4R5)C(R2R3... | 08/16/2005 |
| 6927209 | 5-thio-β-D-xylopryanoside derivatives, preparation, method, pharmaceutical compositions containing them and their therapeutic use The present invention relates to novel compounds of formula (I): in which: R1, R2 and R3, which are identical or different, are each independently: a (... | 08/09/2005 |
| 6914061 | 4′-thio-L-xylofuranosyl nucleosides, precursors thereof, preparation and use thereof Compounds represented by the formula 1: A is selected from the group consisting of wherein each R individually is H or acyl, Y is X, N3,... | 07/05/2005 |
| 6908722 | Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition A novel photoacid generator containing a structure of the following formula (I), wherein R is a monovalent organic group with a fluorine content of 50 wt % or less, a nitro group, a cyano group, or a hydrogen atom, and... | 06/21/2005 |
| 6905786 | Light emitting device material, light emitting device using thereof, and amine compound A compound represented by the following formula (I): wherein R1, R2 and R3each represents an aryl group, a heterocyclic group or an aliphatic hydrocarbon group, provided that at least o... | 06/14/2005 |
| 6900325 | Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof The present invention is directed to substituted coumarins and quinolines and analogs thereof, represented by the general Formula I: wherein A, B, X, Y, and Z are defined herein. The present invention also relates to t... | 05/31/2005 |
| 6890937 | Aromatic sulfone hydroxamic acid metalloprotease inhibitor A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13, while exhibiti... | 05/10/2005 |
| 6875790 | Cyclic sulfone containing retroviral protease inhibitors The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease. ... | 04/05/2005 |
| 6849658 | Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R1 is CH3, —CH2—O—R6, —OR6 or —COR7; R2 is —OR8, —SR8 | 02/01/2005 |
| 6849384 | Photoacid generators, photoresist compositions containing the same and pattering method with the use of the compositions Photoacid generators comprising sulfonium salt compounds represented by the following general formula (2) wherein R1 and R2 represent each an alkyl group optionally having oxo, or R1 and R2 may be cyclized together to form... | 02/01/2005 |
| 6849660 | Antimicrobial biaryl compounds Provided are antibacterial compounds having Formula I: In such compositions, X is O or S; Y is CH2; n is 0 or 1. One of R1 and R1′ is —C(O)NR5R5′ | 02/01/2005 |
| 6846843 | β-thioamino acids Thio-alpha-amino acids of general formula (I), wherein R1, R2 and R3 have the meanings given in the description, methods for producing them, and medicaments containing these compounds. The invention also provides methods for treating... | 01/25/2005 |