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Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
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| Number | Title | Issue Date |
| 8129547 | Anticoagulation of human blood ex vivo The present invention relates to a method for the anticoagulation of human blood ex vivo in which blood calcium concentration remains the same, no thrombin is formed and thrombocyte function is not affected. The invention further relates to a blood coagulation facto... | 03/06/2012 |
| 7429586 | Non-imidazole aryloxyalkylamines Substituted aryloxyalkylamines of formula (I), compositions containing them, and methods of making and using them to treat histamine-mediated conditions. ... | 09/30/2008 |
| RE40525 | Hepatitis C inhibitor tri-peptides A racemate diastereoisomer and optical isomer of a compound of formula (I): wherein B is H, a C6 or C10 aryl, C7-16 aralkyl; Het or (lower alkyl)-Het, all of which may be optionally substituted wi... | 09/30/2008 |
| 7358271 | Sulpiride pharmaceutical compositions The present invention relates to pharmaceutical compositions containing sulpiride compounds having the general formula: where R1 is branched or straight chain alkyl having from 1 to about 7 carbon atoms, a substi... | 04/15/2008 |
| 7335680 | Pyrrolidine derivatives as prostaglandin modulators Substituted pyrrolidine compounds are provided, and methods of treatment and pharmaceutical composition that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing preterm la... | 02/26/2008 |
| 7332512 | Halogenated nitrobutadienes for controlling animal pests The present invention relates to novel halonitrobutadienes, to processes for their preparation and to their use for controlling animal pests. ... | 02/19/2008 |
| 7291753 | Transfer hydrogenation processes and catalysts The invention relates to a process for the reduction of compounds comprising a carbon-carbon (C═C), carbon-oxygen (C═O), or carbon-nitrogen (C═N) double bond, to a corresponding hydrogenated alkane, alcohol or amine, comprising contacting a compound comprising... | 11/06/2007 |
| 7235580 | Mitotic kinesin inhibitors The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention is also related to compositions which c... | 06/26/2007 |
| 7229803 | Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent The invention relates to methods for reacting (di)amines as substrates in the presence of a lysine oxidase arid a reducing agent, resulting in alcohols, diols or cyclic secondary amines. In a particular embodiment, the invention is directed to methods of preparing c... | 06/12/2007 |
| 7220773 | Pyrrole derivative A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R... | 05/22/2007 |
| RE39558 | 5-Substituted-6-cyclic-5,6,7,8-tetrahydronaphthalen 2-ol compounds which are useful for treating osteoporosis Compounds of this formula are useful for treating or preventing, obesity, breast cancer, osteoporosis, endometriosis, cardiovascular disease and prostatic disease. ... | 04/10/2007 |
| 7176229 | Cyclic AMP-specific phosphodiesterase inhibitors Novel pyrrolidine compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as c... | 02/13/2007 |
| 7173129 | Sulfonamide-substituted chalcone derivatives and their use to treat diseases The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the ... | 02/06/2007 |
| 7115754 | Pyrrolidine derivatives as oxytocin antagonists The present invention relates to novel pyrrolidine derivative of formula (I), its geometrical isomers, its optically active forms as enantiomers, diastereomers, mixtures of these and its racemate forms, as well as salts thereof, wherein R1 is selected fro... | 10/03/2006 |
| 7078535 | Method for the production of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-ylacetic acid The invention relates to a process for the preparation of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-ylacetic acid, in which 5-benzyl-3,3-dimethyl-3,4-dihydro-2H-pyrrole is reacted with ω-bromo-4-chloroacetophenone with formation of 6-(4-c... | 07/18/2006 |
| 6995284 | Synthesis of selective androgen receptor modulators The present invention relates to a synthetic process for the preparation of a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subc... | 02/07/2006 |
| 6965038 | Acylated aminothiol compound The present invention discloses an acylated derivative of an aminothiol compound having a general formula II wherein R1-R4 and R6 are substitutable ligands. Such compounds can perform as superior catalysts in asymmetric addition reac... | 11/15/2005 |
| 6864270 | Iron binding agents Composition, article of manufacture for and method of treating malaria in a human having an infestation of Plasmodium protozoans are described. The method comprises administering a therapeutically-effective amount of a compound of formula (I) or (IV), i.e. sufficien... | 03/08/2005 |
| 6749988 | Amine compounds, resist compositions and patterning process Novel amine compounds having a nitrogen-containing cyclic structure and a hydrating group such as a hydroxy, ether, ester, carbonyl, carbonate group or lactone ring are useful for use in resist compositions for preventing a resist film from thinning and also for enh... | 06/15/2004 |
| 6737409 | Dolastatin 10 derivatives Novel anti-tumor compounds of formula, are disclosed. Also disclosed are pharmaceutical compositions comprising compounds of formula (I), the use of compounds of formula (I) for the treatment of cancer, and processes for... | 05/18/2004 |
| 6579971 | Method of producing 3,4-dehydroprolines and 3,4-dehydropiperidines A process for preparing compounds of the formula I ##STR1## in which R is hydrogen, C1 -C6 -alkoxy, --NHC1 -C6 -alkyl, --N(C1 -C6 -alkyl)2, OH, NH2 R1 is hydroge... | 06/17/2003 |
| 6552028 | 2,4-substituted pyrrolidine derivatives-CCR-3 receptor antagonists This invention relates to certain 2,4-substituted pyrrolidine derivatives that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.... | 04/22/2003 |
| 6545157 | Dye-forming method, color developing compositions, photosensitive materials and color developing agent precursors A dye-forming method comprising: reacting a dye-forming coupler and a color developing agent precursor represented by the following general formula (I): ##STR1## wherein A3 represents a group other than a hydrogen atom which leaves, accomp... | 04/08/2003 |
| 6534650 | Benzisoxazole and 4-amidino-3-hydroxyphenyl chemical intermediates This invention relates to compounds of Formula V H--Y--G--R V and Formula VI ##STR1## (wherein f, X, Y, G and R have the values defined in the description) which are useful as intermediates for the preparation of compounds, or pharmaceutically acceptabl... | 03/18/2003 |
| 6515142 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives A process for preparing a compound represented by general formulae (5) and (6) in the following reaction scheme or salts thereof, wherein R1 represents a protective group for a nitrogen atom; R2 represents a methanesulfonyl group or ... | 02/04/2003 |
| 6511980 | Substituted diamine derivatives useful as motilin antagonists The present invention relates to novel substituted diamine derivatives for the formula ##STR1## wherein R1, R2, R3, R4, X1, X2, X3, X4, A, Y and n are as described in ... | 01/28/2003 |
| 6509356 | 1-(4-(Substituted alkoxy)benzyl)naphthalene compounds having estrogen inhibitory activity A class of substituted benzylnaphthylene compounds of the structure ##STR1## where R1 and R2 are independently hydrogen, alkyl of one to six carbon atoms, acyl of two to six carbon atoms, or phenacyl; X is --(CH2)1-6 | 01/21/2003 |
| 6476026 | Compounds and compositions as protease inhibitors The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.... | 11/05/2002 |
| 6441177 | Tertiary amines Tertiary amines of the formula ##STR1## wherein A1, A2, A3, A4, M, p, T and Q are as defined herein, and acid addition salts thereof, have antimycotic and cholesterol-lowering activity.... | 08/27/2002 |
| 6433186 | Amidino derivatives and their use as thormbin inhibitors There is provided compounds of formula I, ##STR1## wherein Y and R1 have meanings given in the description, and pharmaceutically acceptable derivatives (including prodrugs) thereof, which compounds and derivatives are useful as, or are useful a... | 08/13/2002 |
| 6420380 | Hepatitis C inhibitor tri-peptides Racemates, diastereoisomers and optical isomers of a compound of formula (I): ##STR1## wherein B is H, a C6 or C10 aryl, C7-16 aralkyl; Het or (lower alkyl)-Het, all of which optionally substituted with C1-6 alk... | 07/16/2002 |
| 6417371 | Process for preparing 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-ac etic acid The present invention relates to a process process for the preparation of the compound of the formula I ##STR1## where the compound of the formula III ##STR2## is reacted with oxalyl chloride and the product obtained is treated with hydrazine and an ... | 07/09/2002 |
| 6380241 | Treatment of diseases using endothelin antagonists A compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.... | 04/30/2002 |
| 6355632 | Naphthyl compounds, intermediates, compositions, and methods The present invention provides pharmaceutically active compounds formula I ##STR1## wherein R1 is --H, --OH, --O(C1 -C4 alkyl), --OCOC6 H5, --OCO(C1 -C6 alkyl), or --OSO2 (... | 03/12/2002 |
| 6323180 | Hepatitis C inhibitor tri-peptides A racemate, diastereoisomer and optical isomer of a compound of formula (I): ##STR1## wherein B is H, a C6 or C10 aryl, C7-16 aralkyl; Het or (lower alkyl)-Het, all of which may be optionally substituted with C1-... | 11/27/2001 |
| 6180818 | Silver halide photographic material and hydroxamic acid-base compound for use therein A silver halide photographic material is disclosed, comprising a support having thereon at least one light-sensitive silver halide emulsion layer, wherein said silver halide photographic material contains a compound by formula (IA), or which contains at l... | 01/30/2001 |
| 6147224 | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds of Formula 1, Formula 2 or Formula 3 where X is O, S, or (CR1 R1)n where n is 0, 1 or 2; Y is a bivalent radical having Formula 4 or Formula 5 where o is an integer from 1 to 4 ##STR1## or Y is a bivalent ar... | 11/14/2000 |
| 6114570 | Silver halide photographic material and hydroxamic acid-based compound for use therein A silver halide photographic material is disclosed, comprising a support having thereon at least one light-sensitive silver halide emulsion layer, wherein said silver halide photographic material contains a compound by formula (IA), or which contains at l... | 09/05/2000 |
| 6110944 | LTA4, hydrolase inhibitors The present invention provides compounds having the structure Ar1 --Q--Ar2 --O--(CH2)n --Z and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which ar... | 08/29/2000 |
| 6103907 | Phenylalkylcarboxylic acid compounds and compositions for treating hyperglycemia Phenylalkylcarboxylic acid compounds of the formula: ##STR1## wherein R1 represents an alkyl group and the like, R2 represents an alkylene group, R3 represents a hydrogen atom and the like, X represents a substituted ... | 08/15/2000 |
