Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 7973177 | Process for producing cyclic compounds The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of pro... | 07/05/2011 |
| 7939676 | Process for the preparation of levetiracetam A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (−)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting t... | 05/10/2011 |
| 7674916 | Process for producing cyclic compounds The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of pro... | 03/09/2010 |
| RE39744 | Adamantane derivatives and process for producing them In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): wherein R1 and R2 independently represents a hydrogen atom, a halogen atom, an alkyl group... | 07/24/2007 |
| 7199250 | Process for producing cyclic compounds The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of pro... | 04/03/2007 |
| 7193091 | Method for the simultaneous production of tetrahydrofurans and pyrrolidones A process for coproducing alkyl-substituted or unsubstituted THF and pyrrolidones by catalytically hydrogenating C4-dicarboxylic acids and/or derivatives thereof in the gas phase in the presence of copper catalysts and reacting GBL with ammonia or primary amines to ... | 03/20/2007 |
| 7164031 | Method for the production of 2-pyrrolidone A process for continuously preparing 2-pyrrolidone by reacting gamma-butyrolactone with ammonia in the liquid phase in the presence of water, wherein the reaction is carried out at a temperature of from 275 to 300° C. and an absolute pressure of from 140 to 180 bar... | 01/16/2007 |
| 7153978 | Method for purifying N-methyl-2-pyrrolidone A method for purifying N-methyl-2-pyrrolidone is disclosed. The method comprises treating N-methyl-2-pyrrolidone with an alumina that desorbs less than 100 μmol/g of isobutylene between 225° C. and 400° C. in a standard tert-butyl alcohol dehydration test. The me... | 12/26/2006 |
| 7141679 | Process for making N-vinyl-2-pyrrolidone A process for making N-vinyl-2-pyrrolidone (NVP) is disclosed. The process comprises dehydrating N-(2-hydroxyethyl)-2-pyrrolidone (HEP) in the presence of a catalyst and added water. Adding an effective amount of water into the dehydration process reduces the amount... | 11/28/2006 |
| 7129362 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive of levulinic acid esters with aryl and alkyl amines This invention relates to a process for producing 5-methyl-N-aryl-2-pyrrolidone, 5-methyl-N-alkyl-2-pyrrolidone, and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl amines utilizing a metal catalyst, which is op... | 10/31/2006 |
| 7037412 | Method for preparing deodorized N-vinyl-2-pyrrolidone The invention provides a method for producing purified N-vinyl-2-pyrrolidone free of odorous components. The method is composed of distilling with a distillation column a liquid, which is formed by adding to an odorous components-containing liquid having a N-vinyl-2... | 05/02/2006 |
| 7030074 | Production of 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with cyano compounds This invention relates to a process for producing 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl cyano compounds utilizing a m... | 04/18/2006 |
| 7022639 | Catalytic activity accelerant used in petroleum hydrogenation The present invention provides a catalytic activity accelerant. The accelerant is added to stock oil for increasing the catalyst activity, the depth of catalytic hydrogenation and the yield of catalytic hydrogenation product, degrading the reaction conditions of cat... | 04/04/2006 |
| 7015320 | Process for the manufacture of optically active 3-substituted lactams by asymmetric hydrogenation of 3-alkylidenelactams The present invention relates generally to processes for the efficient production optically active 3-substituted lactams of formula (I) process, comprising: contacting a compound of formula (II): ... | 03/21/2006 |
| 7014697 | Production of 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with cyano compounds This invention relates to a process for producing 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl cyano compounds utilizing a m... | 03/21/2006 |
| 7002024 | Production of a N-aryl-2-lactam and N-cycloalkyl-2-lactam by reductive amination of lactones with aryl amines This invention relates to a process for producing N-aryl-2-lactams and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl amines utilizing a metal catalyst, which is optionally supported. ... | 02/21/2006 |
| 6995275 | Production of N-aryl-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl nitro compounds This invention relates to a process for producing N-aryl-2-lactams, N-alkyl-2-lactams, and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl or alkyl nitro compounds utilizing a metal catalyst, which is optionally supported. ... | 02/07/2006 |
| 6992195 | Production of N-aryl-2-lactam and N-cycloalkyl-2-lactam by reductive amination of lactones with arylamines This invention relates to a process for producing N-aryl-2-lactams and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl amines utilizing a metal catalyst, which is optionally supported. ... | 01/31/2006 |
| 6987192 | Production of N-aryl-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl nitro compounds This invention relates to a process for producing N-aryl-2-lactams, N-alkyl-2-lactams, and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl or alkyl nitro compounds utilizing a metal catalyst, which is optionally supported. ... | 01/17/2006 |
| 6987191 | Process for the production of N-methyl pyrrolidone using gamma butyrolactone and mixed methylamines as starting materials A process for the production of N-methyl pyrrolidone using gamma butyrolactone and mixed methylamines as starting materials, in a continuous process, in such operating conditions as to allow the production of high purity N-methyl pyrrolidone in high yields. ... | 01/17/2006 |
| 6984736 | Production of N-aryl-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl nitro compounds This invention relates to a process for producing N-aryl-2-lactams, N-alkyl-2-lactams, and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl or alkyl nitro compounds utilizing a metal catalyst, which is optionally supported. ... | 01/10/2006 |
| 6982339 | Production of N-aryl-2-lactam and N-cycloalkyl-2-lactam by reductive amination of lactones with aryl amines This invention relates to a process for producing N-aryl-2-lactams and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl amines utilizing a metal catalyst, which is optionally supported. ... | 01/03/2006 |
| 6930126 | PRODUCTION OF 5-METHYL-N-(METHYL ARYL)-2-PYRROLIDONE, 5-METHYL-N-(METHYL CYCLOALKYL)-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID ESTERS WITH CYANO COMPOUNDS This invention relates to a process for producing 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl cyano compounds utilizing a m... | 08/16/2005 |
| 6916842 | PRODUCTION OF 5-METHYL-N-(METHYL ARYL)-2-PYRROLIDONE, 5-METHYL-N-(METHYL CYCLOALKYL)-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID ESTERS WITH CYANO COMPOUNDS This invention relates to a process for producing 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl cyano compounds utilizing a m... | 07/12/2005 |
| 6906200 | Production of N-vinyl pyrrolidone N-vinyl pyrrolidone is produced by dehydration of N-hydroxyethyl pyrrolidone in the presence of an amorphous mixed oxide catalyst such as an amorphous Ca/Zn oxide catalyst. ... | 06/14/2005 |
| 6828278 | Production of N-aryl-2-lactam and N-cycloalkyl-2-lactam by reductive amination of lactones with arly amines This invention relates to a process for producing N-aryl-2-lactams and N-cycloalkyl-2-lactams by reductive amination of lactones with aryl amines utilizing a metal catalyst, which is optionally supported. ... | 12/07/2004 |
| 6828277 | Production of N-aryl-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl nitro compounds This invention relates to a process for producing N-aryl-2-lactams, N-alkyl-2-lactams, and N-cycloalky-2-lactams by reductive amination of lactones with aryl or alkyl nitro compounds utilizing a metal catalyst, which is optionally supported. ... | 12/07/2004 |
| 6818593 | Production of 5-Methyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid with nitro compounds This invention relates to a process for producing 5-methyl-N-aryl-2-pyrrolidone, 5-methyl-N-cycloalkyl-2-pyrrolidone, and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid with nitro compounds utilizing a metal catalyst, which is optionally sup... | 11/16/2004 |
| 6726811 | Method of purifying N-(2-hydroxyethy)-2-pyrrolidone A method for obtaining high purity N-(2-hydroxyethyl)-2-pyrrolidone satisfactory for use as an intermediate material for N-vinyl-2-pyrrolidone from a reaction liquid formed of a reaction between y-butyrolactone and 2-aminoethanol, i.e., a liquid containing N-(2-hydr... | 04/27/2004 |
| 6706893 | Methods of making pyrrolidones The present invention provides methods for making N-methylpyrrolidine and analogous compounds via hydrogenation. Novel catalysts for this process, and novel conditions/yields are also described. Other process improvements may include extraction and hydrolysis steps.... | 03/16/2004 |
| 6673920 | Method for the production of N-alkenyl-amides A process for preparing N-alkenyl-amides by reacting the corresponding NH-amides with acetylenes in the liquid phase in the presence of basic alkali metal compounds and of a cocatalyst comprises using as the cocatalyst diols of the general formula (I) ... | 01/06/2004 |
| 6670483 | Methods of making pyrrolidones The present invention provides methods for making N-methylpyrrolidine and analogous compounds via hydrogenation. Novel catalysts for this process, and novel conditions/yields are also described. Other process improvements may include extraction and hydrol... | 12/30/2003 |
| 6632951 | Methods of making pyrrolidones The present invention provides methods for making N-methylpyrrolidine and analogous compounds via hydrogenation. Novel catalysts for this process, and novel conditions/yields are also described. Other process improvements may include extraction and hydrol... | 10/14/2003 |
| 6624303 | Method for producing N-alkenyl amides A process for preparing N-alkenyl-amides by reacting the corresponding NH-amides with acetylenes in the liquid phase in the presence of basic alkali metal compounds and of a cocatalyst comprises using as the cocatalyst compounds of the general formulae (I... | 09/23/2003 |
| 6603021 | Methods of making pyrrolidones The present invention provides methods for making N-methylpyrrolidine and analogous compounds via hydrogenation. Novel catalysts for this process, and novel conditions/yields are also described. Other process improvements may include extraction and hydrol... | 08/05/2003 |
| 6489474 | Process for producing amide compound Object of the present invention is to provide a process for producing an amide compound with high efficiency by subjecting an oxime compound to Beckmann rearrangement in a liquid phase under mild reaction conditions. Namely, the invention relates to a pro... | 12/03/2002 |
| 6436243 | Process for recovering N-vinyl-2-pyrrolidone A process for recovering N-vinyl-2-pyrrolidone is provided which allows to recover N-vinyl-2-pyrrolidone efficiently and steadily and in high purity by continuous distillation from a mixed liquid containing N-vinyl-2-pyrrolidone, N-(2-hydroxyethyl)-2-pyrr... | 08/20/2002 |
| 6392104 | Adamantane derivatives and process for producing them In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): ##STR1## wherein R1 and R2 independently represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a cycloalkyl group; or ... | 05/21/2002 |
| 6348601 | Preparation of N-methyl-2-pyrrolidone (NMP) N-Methyl-2-pyrrolidone (NMP) is prepared by preparing a mixture comprising monomethylamine, dimethylamine and trimethylamine and ammonia in a first process step by reacting ammonia with methanol at elevated temperature in the presence of a catalyst, separ... | 02/19/2002 |
| 6248902 | Process for the production of N-methyl pyrrolidone A process for the production of N-methyl-pyrrolidone obtained by reaction of gammabutyrolactone and mononmethylamine; wherein the synthesis is carried out by a continuous non catalytic process in liquid phase, via three distinct reaction stages connected ... | 06/19/2001 |
