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| Number | Title | Issue Date |
| 7378533 | Method for preparing thermally cleavable surfactants without deprotonation The present invention describes surfactants of formula (I), wherein R, RN, and m are defined herein, processes for their preparation, and methods for their decomposition. ... | 05/27/2008 |
| 6979414 | Organic electroluminescence element An organic electroluminescence element comprising: an anode layer, a cathode layer, and an organic luminescence layer therebetween, the organic luminescence layer having a carbazole derivative with a glass-transition temperature of 110° C. or higher, and a phosphor... | 12/27/2005 |
| 6849619 | Substituted pyridoindoles as serotonin agonists and antagonists The present invention is directed to certain novel compounds represented by structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6, R7, ... | 02/01/2005 |
| 6787651 | Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-γ binding agents Disclosed are substituted indoles, pharmaceutical compositions containing such indoles, and their use in treating or preventing PPAR-γ mediated diseases or conditions, such as osteopenia, osteoporosis, cancer, diabetes and atherosclerosis. ... | 09/07/2004 |
| 6699852 | Substituted pyridoindoles as serotonin agonists and antagonists The present invention is directed to certain novel compounds represented by structural Formula (I) ##STR1## or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6, R7, R8, R9... | 03/02/2004 |
| 6548493 | Substituted heterocycle fused gamma-carbolines The present invention is directed to certain novel compounds represented by structural Formula (I) ##STR1## or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6a, R6b, R7, R8 | 04/15/2003 |
| 6482567 | Oxime sulfonate and N-oxyimidosulfonate photoacid generators and photoresists comprising same New photoacid generator compounds ("PAGs") are provided and photoresist compositions that comprise such compounds. In particular, non-ionic PAGs are provided that contain an oxime sulfonate group, and/or an N-oxyimidosulfonate group. PAGs of the invention... | 11/19/2002 |
| 6218406 | Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents a sub... | 04/17/2001 |
| 6124465 | Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents ... | 09/26/2000 |
| 6013662 | Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents ... | 01/11/2000 |
| 5985908 | MCBI analogs of CC-1065 and the duocarmycins MCBI (7-methoxy-1,2,9a-tetra-hydrocyclopropa[c]benz[e]indol-4-one) is employable as a DNA alkylating agent and can be incorporated into analogs of CC-1065 and the duocarmycins for constructing regioselective DNA alkylating agents.... | 11/16/1999 |
| 5936097 | 4,9-ethano-benzo(F)isoindole derivatives as farnesyl transferase inhibitors Novel products of formula (I): ##STR1## preparation thereof and pharmaceutical compositions containing said products are disclosed. In formula (I), R is a group of formula --(CH2)m --X1 --(CH2)n ... | 08/10/1999 |
| 5843937 | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomer... | 12/01/1998 |
| 5817766 | Reagents for a cannabinoid immunoassay Novel benzpyran derivatives and the use of these derivatives in producing novel anti-cannabinoid antibodies are disclosed. Also disclosed is the use of these antibodies as reagents in improved immunoassays for tetrahydrocannabinol metabolites in biologica... | 10/06/1998 |
| 5629430 | Trifluoromethylpyrroloindolecarboxylic acid ester and process for production thereof Trifluoromethylpyrroloindolecarboxylic acid ester derivatives, and optical isomers and pharmaceutically acceptable salts thereof are provided which are represented by the general formula (1): ##STR1## or the general formula (2): ##STR2## Th... | 05/13/1997 |
| 5457119 | A89271 factors and processes for their production New hapalindole-type alkaloids called A89271 A-F and I are antifungal and antitumor agents. Methods for preparing them and for preparing hapalindoles G and H by culturing the blue-green alga Fischerella ambigua ATCC 55210 are provided. Methods for prepari... | 10/10/1995 |
| 5292650 | Preparation of hapalindole-related alkaloids from blue-green algae New hapalindole-type alkaloids called A89271 A-F and I are antifungal and antitumor agents. Methods for preparing them and for preparing hapalindoles G and H by culturing the blue-green alga Fischerella ambigua ATCC 55210 are provided. Methods for prepari... | 03/08/1994 |
| 5245028 | Process for preparing tetracyclic amines useful as cerebrovascular agents Processes for the preparation of a series of tetracyclic amines useful in the treatment and/or prevention of cerebrovascular disorders are disclosed.... | 09/14/1993 |
| 5212319 | Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor New intermediates, and processes therefor, provide an efficient method for deriving 4-amino-1,2,-2a,3,4,5-hexahydrobenz[cd]indoles, which are themselves intermediates to useful CNS agents, from the Kornfeld-Woodward ketone and like compounds. Preferred em... | 05/18/1993 |
| 5109136 | Tetracyclic amines useful as cerebrovascular agents A novel series of tetracyclic amines, methods of preparation, compositions containing the amines, and methods for using them in the treatment and/or prevention of cerebrovascular disorders are disclosed.... | 04/28/1992 |
| 5070093 | Tetracyclic amines useful as cerebrovascular agents A novel series of tetracyclic amines, methods of preparation, compositions containing the amines, and methods for using them in the treatment and/or prevention of cerebrovascular disorders are disclosed.... | 12/03/1991 |
| 4870185 | Hapalindoles New alkaloids called hapalindoles J-Q and T-V, which are antibacterial and antifungal agents, and methods of preparing these alkaloids by culturing the blue-green alga Hapalosiphon fontinalis ATCC 39694, are provided.... | 09/26/1989 |
| 4782164 | Process for synthesizing active esters of carboxylic acids The invention relates to a new process for preparing active esters or carboxylic acids, which consists in reacting a carboxylic acid, in the presence of an agent for binding hydrohalic acid, with a carbonate of formula: ##STR1## in which R1... | 11/01/1988 |
| 4755610 | Hapalindoles New alkaloids called hapalindoles, which are antibacterial and antifungal agents, and methods of preparing these alkaloids by culturing the blue-green alga Hapalosiphon fontinalis ATCC 39694, are provided.... | 07/05/1988 |
| 4616035 | Pesticidally active novel N-oxalyl derivatives of N-methylcarbamates Combating pests such as insects, arachnids and nematodes with novel N-oxalyl-N-methylcarbamic acid esters of the formula ##STR1## in which R represents alkyl, alkenyl, alkinyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenalkylthio, halog... | 10/07/1986 |
| 4602032 | Dibenz[cd,f]indole derivatives, their preparation and pharmaceutical compositions containing them A 2-alkyl-9,10-dioxy-4,5,5a,6-tetrahydro-dibenz[cd,f]indole or an acid addition salt thereof is a useful anti-parkinson agent.... | 07/22/1986 |
| 4477635 | Polymeric triarylmethane dyes Polymeric and copolymeric aminotriarylmethane dyes having polyester, polyethyleneimine, or polyurethane backbones, and a process for their preparation, are disclosed. The novel dyes are highly colored and resistant to leaching by solvents.... | 10/16/1984 |
| 4470990 | 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants Herein is disclosed compounds of the formula ##STR1## in which R1 and R2 each is hydrogen or lower alkyl or R1 and R2 together form an alkylene of the formula (CH2)n wherein n is an in... | 09/11/1984 |
| 4454325 | N-(Alkenyl)-2-aza-2'-hydroxy-5,6-benzotricyclo[6.3.01,8.04,11 ] u n Novel N-(substituted) derivatives of 2-aza-2'-hydroxy-5,6-benzotricyclo[6.3.01,8.04,11 ] undecane of the formula: ##STR1## are centrally acting analgesics effective in the relief of pain.... | 06/12/1984 |
| 4376779 | N -(Substituted)-2-aza-2'-hydroxy-5,6-benzotricyclo[6.3.01,8.04,1 1 ] undecane centrally-acting analgesics Novel N-(substituted) derivatives of 2-aza-2'-hydroxy-5,6-benzotricyclo[6.3.01,8.04,11 ] undecane of the formula: ##STR1## are centrally acting analgesics effective in the relief of pain.... | 03/15/1983 |
| 4304772 | Ethanocarbazole derivatives and antidepressant compositions Herein is disclosed ethanocarbazole derivatives, acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives. The derivatives are useful for treating depression in a mam... | 12/08/1981 |
| 4182884 | Polycyclic chlorinated hydrocarbons containing bridgehead or imino nitrogen Polycyclic chlorinated amines resulting from cycloadditions useful as insecticides.... | 01/08/1980 |
| 4128560 | Tricyclic alkylamine derivatives Tricyclic alkylamines, and their acid addition salts with pharmaceutically acceptable acids, are disclosed. The tricyclic ring system for these compounds is selected from the group consisting of 1,2,3,4-tetrahydrocyclopent[b]indole, 1,2,3,4-tetrahydrocarb... | 12/05/1978 |
| 4087434 | Hetero-N containing polycyclic chlorinated hydrocarbons resulting from cyclo additions of pentachloro-ଲ-pyrrolenine with olefins Polycyclic chlorinated amines resulting from cycloadditions useful as insecticides.... | 05/02/1978 |
| 4064139 | Substituted 9,10-dihydroanthracen-9,10-imines Substituted 9,10-dihydroanthracen-9,10-imines are disclosed to be minor tranquilizers, anticonvulsnts, muscle relaxants, and to be useful in the treatment of extrapyramidal disorders such as Parkinson's disease; also disclosed are processes for the prepar... | 12/20/1977 |
| 3980641 | Process for the preparation of 14-hydroxymorphinans N-substituted-14-hydroxy-3-substituted-morphinan derivatives have been found to possess potent narcotic agonist or antagonist activity. In particular, the compound 3,14-dihydroxy-N-cyclopropylmethylmorphinan has been found to possess potent agonist-antago... | 09/14/1976 |
| 3950344 | Non-phenol oxidative coupling Oxidative coupling of non-phenolic compounds is attained by subjecting said non-phenolic compound to oxidizing conditions in contact with an oxidant selected from the group of VOF3, MoOCl4, Pb3 O4, Tl(CF3 | 04/13/1976 |