Class 548/419 - Two of the cyclos share at least three ring members, or a ring carbon is shared by three of the cyclos (e.g., bridged, peri-fused, etc.)

Subclass of Class 548 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein at least three ring members of one cyclo
No. of patents: 36
Last issue date: 06/10/2003

Number	Title	Issue Date
6576780	Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors The current invention discloses hydroxyamidino derivatives useful as nitric oxide synthase inhibitors....	06/10/2003
6124465	Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents ...	09/26/2000
6107345	Benzocyclobutane compounds A compound of formula (I): ##STR1## wherein: Z1, Z2, Z3, Z4, which may be identical or different, represent a group as defined in the description, X represents oxygen, S(O)p, --(CH2)n	08/22/2000
5968933	DNA-targeted alkylating agents The invention relates to novel bis-benzimidazole compounds which have the ability to bind to the minor groove of DNA and to alkylate DNA, to methods of preparing the compounds, and the use of the compounds in the treatement of neoplastic disease....	10/19/1999
5457119	A89271 factors and processes for their production New hapalindole-type alkaloids called A89271 A-F and I are antifungal and antitumor agents. Methods for preparing them and for preparing hapalindoles G and H by culturing the blue-green alga Fischerella ambigua ATCC 55210 are provided. Methods for prepari...	10/10/1995
5411960	Substituted pyrroloanthracenes and -diones Substituted pyrroloanthracenes are prepared by reacting either furanoanthracenes or N-unsubstituted pyrroloanthracenes with appropriately substituted alkylamines. The compounds can be employed as active ingredients in medicaments, in particular as immunom...	05/02/1995
5302589	Heterocyclic inhibitors of 5-଱-testosterone reductase The present invention relates to certain substituted 17 ଲ-substituted carbonyl-6-azaandrost-4-en-3-ones of formula (I): ##STR1## wherein R1 and R2 are i) independently hydrogen or lower alkyl and the bond between the carbons ...	04/12/1994
5264538	Cyclic poly(aryl ether) oligomers Cyclic poly(aryl ether) oligomers and mixtures thereof, and methods for the preparation thereof in a highly dilute reaction medium under reaction conditions favorable for ring closure at low degrees of polymerization. These oligomers are represented by th...	11/23/1993
5137908	4-azahexacyclododecane compounds 4-Azahexacyclo (5.4.1.02,6 .03,10 .05,9 .08,11) dodecane compounds of the formula ##STR1## wherein R, A and B each is hydrogen; a linear or branched alkyl group having one to twelve carbon atoms and optiona...	08/11/1992
4988710	Aryl-cycloalkyl-alkanolamines for treatment of cholinergic neurotoxins A compound and method are disclosed for reducing neurotoxic effects (such as seizures and brain damage) caused by cholinergic agents such as soman (a nerve gas) and pilocarpine (a convulsant drug used to study the mechanisms of epilepsy). Effective treatm...	01/29/1991
4960860	Imide compound and composition containing the same The present invention provides an improved epoxy resin composition comprising an epoxy resin and a novel imide compound represented by the formula ##STR1## wherein X represents an --NH2 group and/or --OH group, Ar1 and Ar	10/02/1990
4939012	Naphtholactam dyes and optical recording medium containing these dyes Naphtholactam dyes of the formula ##STR1## where R1, R2, R3, R4, R5, n, p, Z1, Z2 and the rings A, B, C and D each have the meanings stated in the description, and an optica...	07/03/1990
4876356	Naphtholactam dyes and optical recording medium containing these days Naphtholactam dyes of the formula ##STR1## where R1, R2, R3, R4, R5, n, p, Z1, Z2 and the rings A, B, C and D each have the meanings stated in the description, and an optica...	10/24/1989
4830951	Naphtholactamsquaric acid dyes and optical recording materials containing these dyes Naphtholactamsquaric acid dyes of the formula ##STR1## where R1 and R2 independently of one another are each unsubstituted or substituted C3 -C22 -alkyl, in which the alkyl chain may be interrupted by oxyge...	05/16/1989
4820846	Triarylmethane compounds, their preparation and use as photoconductive systems Compounds which are useful as sensitizers of photoconductors, having the general formula: ##STR1## in which: like symbols represent identical substituents, at least 4 of R1 to R9 represent hydrogen atoms and the remaining R...	04/11/1989
4670461	Formaldehyde derivatives of mitindomide New substituted, formaldehyde derived mitindomide and methods of preparing the same are disclosed. The novel compounds are water soluble and have anti-neoplastic activity. The formaldehyde derived mitindomide is prepared by reacting mitindomide with forma...	06/02/1987
4555563	Imide functional polyphenols; thermosettable compositions containing same and cured products therefrom Imide functional polyphenols are prepared by reacting an excess of a phenol with an unsaturated diimide which is prepared by reacting an unsaturated polycycloaliphatic dicarboxylic acid anhydride with a diamine. These materials are useful in the preparation of...	11/26/1985
4465688	9,10-Dihydro-1,8,9-trihydroxy-9,10-anthracene ଱,ଲ-endosuccinimide,଱,ଲ-endosuccinic acid and ଱ଲ-endomaleic acid and derivative thereof The invention concerns adducts of 1,8-dihydroxy-9-anthrone, of formula: ##STR1## in which: R1 and R2, taken together, form one of the following divalent residues: ##STR2## R3, R4, R'4, R	08/14/1984
4417057	N-Substituted imides and bis-imides Compounds of the formulae I or II ##STR1## and processes for their preparation are described. In the above formulae, Z is a tetravalent aliphatic radical, which can be interrupted by hetero-atoms, or a substituted or unsubstituted tetravalent cycloal...	11/22/1983
4322528	Polycyclic chlorinated hydrocarbons containing bridgehead or imino nitrogen Polycyclic chlorinated amines resulting from cycloadditions useful as insecticides....	03/30/1982
4301075	N-Substituted imides and bis-imides Compounds of the formulae I or II ##STR1## and processes for their preparation are described. In the above formulae, Z is a tetravalent aliphatic radical, which can be interrupted by hetero-atoms, or a substituted or unsubstituted tetravalent cycloal...	11/17/1981
4283536	Preparation of vincadifformine and related derivatives This invention relates to the preparation of vincadifformine and related derivatives which are useful as starting material for the synthesis of among other alkaloids vincamine and other similar compounds possessing interesting psychopharmacologic properti...	08/11/1981
4271074	Silanes containing imide groups The compounds according to the invention have the formula I ##STR1## in which R1, R2 and R3 are monovalent organic radicals or chlorine and Z is a tetravalent organic radical and A is a divalent organic grouping. Thes...	06/02/1981
4267330	Process for the synthesis of vincadifformine and related derivatives This invention relates to the preparation of vincadifformine and related derivatives which are useful as starting material for the synthesis of vincamine and other related compounds possessing interesting psychopharmacologic properties. A N-benzyl-tetrahy...	05/12/1981
4234488	Benz-[c,d]-indolyl compounds The invention relates to compounds of the formula ##STR1## wherein Z denotes OH or NR1 R2, R1 denotes hydrogen, alkyl, aralkyl, cycloalkyl or aryl, R2 denotes hydrogen or alkyl or, conjointly with R1, form...	11/18/1980
4123546	Antidepressant compounds Antidepressant compounds such as 2-[(4b,4c-dihydro-8bH-azirino[2,1,3-cd]dibenzo[a,f]pyrrolizin-8b-yl)oxy]et hyl-N,N-dimethylamine useful for alleviating depression in mammals....	10/31/1978
4088772	Methanodibenzocycloheptapyrroles Methanodibenzocycloheptapyrroles, such as 2-cyclopentylmethyl-2,3,8,12b-tetrahydro-1H-3a, 8-methanodibenzo[3,4:6,7]cyclohepta[1,2-c]pyrrole, useful as tranquilizers and analgesics....	05/09/1978
4081448	Bridgehead nitrogen analogs of poly-chlorinated cyclic hydrocarbon insecticides A compound having one of the structural formulae: ______________________________________ a) ##STR1## and hydrogenated, chlorinated and brominated derivatives thereof; b) ##STR2## c) #...	03/28/1978
4077977	Ethenoanthracenes Compounds of the formula: ##STR1## where R1 and R2 are various substituents and X is a bridge having a chain of 3 atoms, including N, are made by internal Diels-Alder reaction of alkynyl-substituted anthracenes. The compounds ar...	03/07/1978
4076830	Alkylmethanodibenzocycloheptapyrroles Certain 1-alkyl and 8-alkylmethanodibenzocycloheptapyrroles and their salts are useful as tranquilizers and analgesics. Exemplary are 2-cyclopentylmethyl-1-methyltrans-2,3,8,12b-tetrahydro-1H-3a,8-methanodibe nzo[3,4:6,7]cyclohepta[1,2-c]pyrrole hydrochlor...	02/28/1978
4073794	7,8 Diacyl bicyclo[2.2.2]bis(2,3-dicarboximide) compounds 7,8-Diacyl bicyclo[2.2.2]oct-5-ene-bis(2,3-dicarboximide) and 7,8-diacyl bicyclo[2.2.2]octane-bis(2,3-dicarboximide) compounds useful for the production of polyimides....	02/14/1978
4070366	Alkylation process Substituted pyrrole compounds, such as 3-ethyl-4-methyl-5-carbethoxy pyrrole, 2,4-dimethyl-3-acetyl pyrrole and 2-methyl-5-carboxy pyrrole-4-propionic acid diethyl ester, are alkylated in a single step by reaction with an aldehyde or ketone in the presenc...	01/24/1978
4036978	Ethanodibenzoindoles Substituted and unsubstituted ethanodibenzoindoles, for example, 3-chloro-1-methyl-1,2-dihydro-6,10b-ethanodibenzo[cd,g] indole, are prepared by cyclizing and reducing N-naphthylbenzamides and are useful as anti-inflammatory agents....	07/19/1977
3998823	Novel derivatives of maleopimaric acid Novel derivatives of maleopimaric acid of the formula: ##STR1## The compounds of the invention exhibit hepato-protective activity....	12/21/1976
3963747	Basic arylmercaptonaphtholactam dyes Basic dyes of the naphtholactam series substituted by an arylmercapto radical. The dyes are eminently suitable for dyeing anionically modified fibers, particularly acrylonitrile polymers, and give blue to blue green shades of excellent fastness properties...	06/15/1976
3950340	Quinazoline dyes Dyes of the formula: ##SPC1## In which R is unsubstituted or substituted alkyl or aralkyl; R1 to R6 is each hydrogen or a substituent; R7 is hydrogen or alkoxy; R8 is hydrogen or alkoxy; n is zero or 1; X- is a...	04/13/1976

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Class 548/419 - Two of the cyclos share at least three ring members, or a ring carbon is shared by three of the cyclos (e.g., bridged, peri-fused, etc.)