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| Number | Title | Issue Date |
| 7910746 | Haloalkyl carboxamides New haloalkyl carboxamides of formula (I) in which R, R1, R2, R3, R4, M and A have the meanings specified in the description, several processes for sy... | 03/22/2011 |
| 7767827 | Pyrazole-1-carboxylate derivatives, process for the production thereof and process for the production of pyrazole derivatives Disclosed are pyrazole-1-carboxylate derivatives of the general formula (1), (wherein symbols are as defined in the specification), a process for the production thereof and processes for p... | 08/03/2010 |
| 7425640 | Substituted 5-carboxyamide pyrazoles and [1,2,4]triazoles as antiviral agents The present invention provides compounds of formula I wherein X, Y, R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders... | 09/16/2008 |
| 7183306 | Pyrazole derivatives A compound of the formula (I): wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, etc.; R3 is lower alkoxy, etc.; ... | 02/27/2007 |
| 7115749 | Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents The present invention provides compounds of formula I wherein X and R1–R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorde... | 10/03/2006 |
| 7109228 | Pyrazole derivatives This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, and to processes for the preparation thereof, intermediates used in their prepa... | 09/19/2006 |
| 7017496 | Kinetic energy rod warhead with imploding charge for isotropic firing of the penetrators A kinetic energy rod warhead with imploding charges for isotropic firing of penetrators including a hull, a core in the hull including a plurality of individual penetrators, explosive charge sections in the hull about the core, and a detonator for each explosive cha... | 03/28/2006 |
| 6949550 | Substituted amino methyl factor Xa inhibitors The present application describes substituted-aminomethyl substituted compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa. ... | 09/27/2005 |
| 6931994 | Tandem warhead A tandem warhead for destroying a target, the tandem warhead including a kinetic energy rod section with a plurality of lengthy individual projectiles, a blast fragmentation section deployable proximate the target, and a guidance subsystem for deploying the projecti... | 08/23/2005 |
| 6686318 | Heterocyclically substituted aromatic amino compounds with a herbicidal effect The invention relates to new substituted aromatic amino compounds of the general formula (I) ##STR1## in which R1, R2, R3, R4 and Z have the meanings given in the description, to a process for their preparation,... | 02/03/2004 |
| 6627643 | Methods for preparing sodium-hydrogen exchanger type-1 inhibitors This invention relates to methods of preparing sodium-hydrogen exchanger type 1 (NHE-1) inhibitors of formula I' ##STR1## and methods of preparing pharmaceutical compositions comprising such NHE-1 inhibitors.... | 09/30/2003 |
| 6518266 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides The present invention is directed to novel pyrazole derivatives and their use as pesticidal agents. The pyrazole derivatives have Formula I: ##STR1## or a salt thereof, where R1 represents R5 O, R5 SO2, R5... | 02/11/2003 |
| 6518296 | Substituted 3-thiocarbamoylpyrazoles The invention relates to novel substituted 3-thiocarbamoylpyrazoles of general formula (I), wherein m, n, R1, R2, R3 and Ar have the meanings cited in the description. The invention further relates to methods for the produ... | 02/11/2003 |
| 6465656 | Synthesis of 1,3,5-trisubstituted pyrazoles A novel process for making 1,3,5-trisubstituted pyrazoles of the type shown below from appropriate phenyl hydrazines is described. ##STR1## These compounds are useful as factor Xa inhibitors.... | 10/15/2002 |
| 6451790 | Azadioxacycloalkenes and their use for combating harmful fungi and animal pests Compounds of formula I ##STR1## wherein W is optionally substituted alkylene; Y is N or CRa ; Ra is hydrogen, halogen or alkyl; R1n represents hydrogen or 1 to 4 substituents; R2 is hydrogen, nitro, cyano, halo... | 09/17/2002 |
| 6331640 | Diaminopropionic acid derivatives A compound of formula 1a ##STR1## which is useful for treating reperfusion injury, and salts, prodrugs, and related compounds.... | 12/18/2001 |
| 6020357 | Nitrogen containing heteroaromatics as factor Xa inhibitors The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(.dbd.NH)NH2, which are u... | 02/01/2000 |
| 5968967 | Pyrazolones derivatives A pyrazolone derivative represented by general formula (I) or a salt thereof: ##STR1## [wherein one of X1 and X2 is ##STR2## (wherein A is a cyano group, a cyano C1-4 alkyl group, an amino group, an amino C | 10/19/1999 |
| 5948777 | Cannabinoid receptor agonists Novel pyrazole derivatives are provided which are cannabinoid receptor agonists.... | 09/07/1999 |
| 5744493 | 3-amidopyrazole derivatives and pharmaceutical compositions containing them The present invention relates to new pyrazole derivatives possessing an amide group substituted with an amino acid or one of its derivatives at position 3 and variously substituted in positions 1, 2, 4 or 5 of the pyrazole ring, to a process for preparing... | 04/28/1998 |
| 5672710 | Sulfides, sulfoxides and sulfones disubstituted with a tetrahydronaphthalenyl, chromanyl, thiochromanyl or tetrahydroquinolinyl and substituted phenyl or heteroaryl group, having retinoid-like biological activity | 09/30/1997 |
| 5672617 | Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock This application relates to new thiocarbamoyl compounds of the formula (I) ##STR1## in which R1, R2, R3 and R4 have the meanings given in the description.... | 09/30/1997 |
| 5643926 | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof Novel substituted pyrazolidinones have been found to exhibit significant binding to cholecystokinin (CCK) receptors and gastrin receptors in the brain and/or peripheral sites such as the pancreas, stomach, and ileum. The pyrazolidinones are CCK and gastri... | 07/01/1997 |
| 5635526 | 3-amidopyrazole derivatives, process for preparing these and pharmaceutical compositions containing them The present invention relates to new pyrazole derivatives possessing an amide group substituted with an amino acid or one of its derivatives at position 3 and variously substituted in positions 1, 2, 4 or 5 of the pyrazole ring, to a process for preparing... | 06/03/1997 |
| 5596064 | Polyisocyanates blocked with a mixture of blocking agents Blocked polyisocyanates containing aliphatically and/or cycloaliphatically bound isocyanate groups blocked by a mixture of blocking agents containing A) 30 to 70 equivalent % of 1,2,4-triazole, B) 30 to 70 equivalent % of 3,5-dimethylpyrazole, and C) 0 to 30 equiva... | 01/21/1997 |
| 5556987 | Process for producing pyrazolecarboxamide derivative A process for producing a pyrazolecarboxamide derivative represented by formula (C) which comprises reacting a pyrazolecarboxylic ester compound represented by formula (A) with an amine compound represented by formula (B) in the presence of a Lewis acid: ... | 09/17/1996 |
| 5543529 | 1-carbamoyl-5-hydroxypyrazole compounds and salts thereof Pyrazole compounds represented by formulae (A), (B), and (C): ##STR1## wherein R1 represents an unsubstituted alkyl group, an ester group, a carboxyl group, an amino group or an aryl group; R2 and R3 each represents a... | 08/06/1996 |
| 5541214 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity Amides of pyrazolecarboxy acids having the general formula (I): ##STR1## exhibiting a high insecticidal and acaricidal activity.... | 07/30/1996 |
| 5510365 | Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock The invention relates to the use of 1-thiocarbamoyl-5-hydroxypyrazoles of the general formula ##STR1## in which the substituents denote the radicals mentioned in the description, as pharmaceutical agents for combating septic shock and the conseq... | 04/23/1996 |
| 5502069 | 1-thiocarbamoyl-5-hydroxy-pyrazoles as microbicides 1-Thiocarbamoyl-5-hydroxy-pyrazoles have a microbicidal action and are therefore suitable for use for the preservation of materials. Since, in contrast to other microbicides, they are ecologically acceptable and do not discolour plastics, paints and paint... | 03/26/1996 |
| 5438070 | Carboxanilides, their preparation and compositions containing them for controlling harmful fungi Carboxanilides of the formula I where the substituents have the following meanings: R is substituted or unsubstituted alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl, alkynyloxy, cycloalkyl, cycloalkenyl, cycloalkyloxy, cycloalkenyloxy or phenyl; A is one of... | 08/01/1995 |
| 5424279 | Pyrazole derivatives having herbicidal activity and their use Compounds of formula (I): ##STR1## (in which: R1 and R2 are each hydrogen, optionally substituted alkyl, optionally substituted alkenyl, alkynyl, alkoxy, aryl or pyridyl, or R1 and R2 together represent alk... | 06/13/1995 |
| 5416220 | Processes for preparation of 5-pyrazolemercaptan derivatives The present invention relates to a process for preparation of 5-pyrazolemercaptan derivatives represented by the following general formula (I), which is useful for synthesis of sulfonylurea-based herbicides, and an intermediate thereof, ##STR1## ... | 05/16/1995 |
| 5405965 | Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof The present invention relates to a process for preparation of 5-pyrazolemercaptan derivatives represented by the following general formula (I), which is useful for synthesis of sulfonyl-urea-based herbicides, and an intermediate thereof, ##STR1## ... | 04/11/1995 |
| 5399565 | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations therof Novel substituted pyrazolidinones have been found to exhibit significant binding to cholecystokinin (CCK) receptors and gastrin receptors in the brain and/or peripheral sites such as the pancreas, stomach, and ileum. The pyrazolidinones are CCK and gastri... | 03/21/1995 |
| 5342942 | Pyrazoloquinazolone derivatives as neurotrophic agents Pyrazolo[5,1-b]quinazoline compounds, salts thereof, methods of production, intermediates in their production, pharmaceutical compositions containing said compounds, and methods for treating neurodegenerative disorders, tumors of neuronal origin, inflamma... | 08/30/1994 |
| 5319099 | 3-benzylidene-1-carbamoyl-2-pyrrolidone compounds useful as antiinflammatory agents The present invention relates to novel 3-benzylidene-1-carbamoyl-2-pyrroridone analogues having advantage anti-inflammatory activities, which is represented by the formula: ##STR1## wherein R1 and R2 each is independently hydrog... | 06/07/1994 |
| 5300514 | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof Novel substituted pyrazolidinones have been found to exhibit significant binding to cholecystokinin (CCK) receptors and gastrin receptors in the brain and/or peripheral sites such as the pancreas, stomach, and ileum. The pyrazolidinones are CCK and gastri... | 04/05/1994 |
| 5276147 | Compounds and complexes useful in medical imaging The subject of the present invention is compounds which correspond to the following general formula: ##STR1## in which R1 and R3 independently of one another represent H, an alkyl, alkenyl, cycloalkyl, aryl, arylalkyl or an alky... | 01/04/1994 |
| 5252540 | Sulfonamides Sulfonamides of the formula I ##STR1## where A is an unsubstituted or substituted aromatic or heteroaromatic radical; W is oxygen or sulfur; B is an unsubstituted or substituted furyl, thienyl, pyrrolyl, oxazolyl, isothiazolyl, imidazolyl, pyrazolyl,... | 10/12/1993 |
