Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7227043 | 2-phenyl-2-substituted-1,3-diketones The invention relates to novel phenyl-substituted cyclopentane- and cyclohexane-1,3-dione derivatives of the formula (I) in which W, X, Y, Z, A, B, Q1, Q2, Q3 | 06/05/2007 |
| 7183238 | [1,2]-oxazine-3,5-diones The present invention relates to novel [1,2]-oxazine-3,5-dione derivatives of the formula (I) in which W, X, Y, Z, G, D, A and B are as defined in the disclosure, to a pl... | 02/27/2007 |
| 7067548 | Control of arthropods in animals A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole. ... | 06/27/2006 |
| 6946474 | Nitrogen-containing compounds and their use as glycine transport inhibitors The present invention provides trichloroethyl-sulfonylurea-containing compounds that inhibit glycing transporters, pharmaceutical compositions comprising such compounds, methods for using such compounds for inhibiting glycine transporters and methods for using such ... | 09/20/2005 |
| 6838458 | 5-(alkylidene-cycloalkyl)-and 5-(alkylidene-heterocyclyl)-pyrazoles The present invention relates to 5-(alkylidene-cycloalkyl)-pyrazoles and 5-(alkylidene-heterocyclyl)-pyrazoles of the formula I: wherein the ring of the formula (R5)-A-(SOmR4), m, B, ri... | 01/04/2005 |
| 6812347 | Processes for the preparation of pesticidal compounds and novel intermediates thereof A process for the preparation of a compound of the formula (I): wherein R1 is CN or CSNH2; X is N or CR4; R2 and R4 are each independently hydrogen or chloro; R | 11/02/2004 |
| 6686318 | Heterocyclically substituted aromatic amino compounds with a herbicidal effect The invention relates to new substituted aromatic amino compounds of the general formula (I) ##STR1## in which R1, R2, R3, R4 and Z have the meanings given in the description, to a process for their preparation,... | 02/03/2004 |
| 6630499 | Control of arthropods in animals A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.... | 10/07/2003 |
| 6531501 | Control of arthropods in animals A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.... | 03/11/2003 |
| 6518296 | Substituted 3-thiocarbamoylpyrazoles The invention relates to novel substituted 3-thiocarbamoylpyrazoles of general formula (I), wherein m, n, R1, R2, R3 and Ar have the meanings cited in the description. The invention further relates to methods for the produ... | 02/11/2003 |
| 6451736 | Substituted aromatic thiocarboxylic acid amides and their use as herbicides There is disclosed substituted thiocarboxamides compounds of the formula (I): ##STR1## wherein R1, R2, R3 and Z are as defined in the specification. The compounds are useful as herbicides.... | 09/17/2002 |
| 6380214 | Heterocyclic derivatives useful as anticancer agents The present invention relates to compounds of the formula 1 ##STR1## and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein Z, X, X1, R1, R2 and R3 are as defined herein as it relates t... | 04/30/2002 |
| 6372773 | Aromatic heterocyclic compounds as antiinflammatory agents Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving in... | 04/16/2002 |
| 6136983 | Pesticidal sulfur compounds Pyrazole, pyrrole and imidazole derivatives having formula (I) or (II): ##STR1## wherein .dbd.X is .dbd.NR3, .dbd.O or an electron pair and Q comprises certain pyrazole, pyrrole and imidazole structures which, together with the remaining s... | 10/24/2000 |
| 6080763 | Aromatic heterocyclic compounds and their use as anti-inflammatory agents Novel aromatic heterocyclic compounds inhibit cytokines production involved in immunoregulation and inflammation such as interleukin-1 and tumor necrosis factor production. The compounds are therefore useful in pharmaceutic compositions for treating disea... | 06/27/2000 |
| 5880289 | Crystallization method Disclosed is a method of crystallizing coupler crystals, the method comprising the steps of dissolving crude crystals of a coupler in a first solvent having a first solubility parameter to obtain a coupler solution; and adding to the solution a second sol... | 03/09/1999 |
| 5801284 | Hydrogenation of halonitroaromatic compounds Process for preparing haloaromatic amines by catalytic hydrogenation of the corresponding halonitroaromatic compounds, characterized in that iron-containing Raney nickel is used as catalyst, where the haloaromatic amines prepared can be used for the synth... | 09/01/1998 |
| 5663434 | Process for preparing N-(3-amino-4-chlorophenyl) acylamides The present invention provides a process for preparing N-(3-amino-4-chlorophenyl) acylamides of Formula I: ##STR1## comprising reacting, in a solvent comprising at least one polar solvent, in the presence of at least one acid acceptor, 1-chloro-2,4-d... | 09/02/1997 |
| 5637607 | Pesticidal 1-arylpyrazoles Compounds of the formula 1-(4-SF5 2-R2 6-R6 phenyl) 3-CN 4-S(O)n R4 5-N(R1)(R3) pyrazole, pesticidal compositions comprising them and related methods of controlling pests are dis... | 06/10/1997 |
| 5629335 | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters 1-(Substituted phenyl)-3-(thioimidate)pyrazoles having systemic activity, arthropodicidal (especially insecticidal) and nematocidal compositions comprising same and methods for controlling arthropods (especially insects) and nematodes.... | 05/13/1997 |
| 5608077 | Derivatives of n-phenylpyrazoles N-Phenylpyrazole derivatives of the formula: ##STR1## wherein R1 represents cyano, nitro, halogen, acetyl or formyl; R2 represents R5 SO2, R5 SO or R5 S in which R5 is optionally... | 03/04/1997 |
| 5583255 | Yellow and magenta chromogenic leuco dyes for photothermographic elements Photothermographic elements capable of producing a high density yellow or magenta image upon image-wise exposure and thermal development at a relatively low temperature and for a short period of time are described. The photothermographic elements of the i... | 12/10/1996 |
| 5580843 | Substituted 1-arylpyrazoles The invention relates to new substituted 1-arylpyrazoles of the general formula (I) ##STR1## to a plurality of processes for their preparation, and to their use as pesticides.... | 12/03/1996 |
| 5556873 | Pesticidal 1-aryl-5-(substituted alkyl (thio) amido)pyrazoles The invention describes novel 1-aryl-5-(substituted alkyl (thio)amido)pyrazoles wherein preferred compounds are of the formula ##STR1## wherein: R2 is R11 S(O)n in which n is 0, 1 or 2 and R11 is alkyl, pre... | 09/17/1996 |
| 5554633 | Substituted amines as tachykinin receptor antagonists Compounds of formula (I), and salts and prodrugs thereof, wherein Q is optionally substituted phenyl or benzhydryl; X and Y are each H or together form a group=O; Z is O, S or NR9, where R9 is H or C1-6 alkyl; R1 | 09/10/1996 |
| 5543529 | 1-carbamoyl-5-hydroxypyrazole compounds and salts thereof Pyrazole compounds represented by formulae (A), (B), and (C): ##STR1## wherein R1 represents an unsubstituted alkyl group, an ester group, a carboxyl group, an amino group or an aryl group; R2 and R3 each represents a... | 08/06/1996 |
| 5541215 | Heterocycle-substituted benzenemethanamine derivatives The present invention is concerned with antiretroviral (e.g. anti-HIV-1) compounds having the formula ##STR1## wherein R1 and R2 each independently are halo or methyl; R3 is hydrogen, halo, nitro or trifluoromethyl; R... | 07/30/1996 |
| 5523280 | Phenylpyrazole fungicides Phenylpyrazoles of the formula: ##STR1## in which: X.dbd.H, hal, NO2, CN, SCN, alkyl (C1 -C4), alkenyl (C2 -C4), alkynyl (C2 -C4), alkoxy (C1 -C4), alk... | 06/04/1996 |
| 5464860 | N(pyrazol-3-yl) benzamides and pharmaceutical compositions The invention relates to a compound useful for treating epilepsy selected from the compounds of the general formula: ##STR1## in which R1 is C1 -C4 alkyl, R2 is C1 -C4 alkyl, R3 ... | 11/07/1995 |
| 5441975 | Pyrazolo-substituted alkyl amide acat inhibitors Pharmaceutically useful compounds having ACAT inhibitory activity of the formula ##STR1## wherein n is 0, 1, or 2, for X other than tetrazole and n=2 then R2 =R3 =H; R1 is phenyl, substituted phenyl, naphthyl, substit... | 08/15/1995 |
| 5424475 | Thermal imaging dye precursors Colorless precursors of preformed image dyes are provided which are useful as the color image-forming materials in thermal imaging systems. These colorless precursors possess at least one thermal protecting group that undergoes fragmentation upon heating ... | 06/13/1995 |
| 5340832 | Prolinal derivatives useful for treating amnesia A novel prolinal derivative of the general formula: ##STR1## [wherein A represents alkylene or alkenylene group of from 1 to 8 carbon atom(s) or a saturated hydrocarbon ring of from 3 to 7 carbon atoms, R represents hydrogen atom, phenyl group, benzy... | 08/23/1994 |
| 5162528 | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives The invention relates to the use of partly known substituted pyrazolin-5-one derivatives of the formula (I) ##STR1## as herbicides and fungicides, new substituted pyrazolin-5-one derivatives and processes for their preparation.... | 11/10/1992 |
| 5122611 | Method of producing azomethine or indoaniline series dyes A method for producing an azomethine or indoaniline series dye, which comprises oxidatively condensing an active methylene- or methine-containing compound, except those containing a sulfonic or carboxylic acid group, and p-phenylenediamine, except those c... | 06/16/1992 |
| 5081259 | Novel amino acid substituted 4-aminophenazones for measuring enzyme activity Novel substrates which are amino acid 4-amino phenazones for detecting enzymes, particularly L-gamma-glutamyltransferase, are described. The amino acid gamma-glutamyl-4-aminophenazone reacts with the enzyme to produce 4-aminophenazone which is an amino dy... | 01/14/1992 |
| 5055482 | N-phenylpyrazol-4-yl ether derivatives An N-phenylpyrazol-4-yl ether derivative of the formula: ##STR1## wherein R1 represents halogen, alkyl or alkoxy unsubstituted or substituted by halogen, alkylthio or alkylsulphinyl substituted by one or more halogen atoms, nitro, cyano, o... | 10/08/1991 |
| 4971989 | Substituted 1-arylpyrazoles, pesticidal compositions and use Substituted 1-arylpyrazoles useful in combating insects having the arachnida and nematodes of the formula ##STR1## in which R1 represents hydrogen or alkyl, R2 represents alkyl or halogenoalkyl, R3 represents hydrogen or a... | 11/20/1990 |
| 4946965 | Process for drying solid photographic addenda Solid photographic addenda, such as photographic color couplers or sensitizing dyes, which are wet with occluded organic liquid, after being subjected, for example, to processes such as crystallization or washing, are contacted with an extractant composed... | 08/07/1990 |
| 4945165 | Pest-combating agents based on pyrazole derivatives A 5-aminopyrazole of the formula (I) ##STR1## in which R2 represents CF3 or CCL2 F, R3 represents hydrogen or CH3 and n represents the number 0 or 1. The 5-aminopyrazole of formula (I) is effective in comb... | 07/31/1990 |
| 4933465 | Silver halide color photographic material A magenta color - forming coupler represented by the formula (1) for use in color photographic silver halide photosensitive material: ##STR1## wherein X is halogen; l is 0, 1, 2, or 3; Y is hydrogen or halogen; Q is --NH-- or --NHCO--; n is 1, 2, or ... | 06/12/1990 |
