Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 7807843 | 1-substituted-4-nitroimidazole compound and method for preparing the same The present invention relates to a 1-substituted-4-nitroimidazole compound represented by the general formula (1) or a salt thereof, (wherein R is a hydrogen atom, a lower alkoxy group-substituted lower alkyl group, a pheny... | 10/05/2010 |
| 7442713 | 2-thio-substituted imidazole derivatives and their use in pharmaceutics The invention relates to 2-thio-substituted imidazole derivatives of the formula I in which the radicals R1, R2, R3, R4 and p are as defined in the description. The compounds acco... | 10/28/2008 |
| 7439370 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides The invention relates to new substituted imidazoles of general formula wherein R1 to R3 and X are defined as claims, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salt... | 10/21/2008 |
| 7439371 | Indol kinase inhibitors The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. ... | 10/21/2008 |
| 7410995 | N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using N-linked sulfonamides of heterocyclic thioesters. ... | 08/12/2008 |
| 7407977 | Substituted N-acyl-2-aminothiazoles There are presented compounds of the formula or a pharmaceutically acceptable salt thereof, which are useful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhea. ... | 08/05/2008 |
| 7399868 | 4-(Heteroaryl-methyl and substituted heteroaryl-methyl)-imidazole-2-thiones acting as alpha2 adrenergic agonists Compounds of Formula 1 where the variables have the meaning defined in the specification are agonists of alpha2 adrenergic receptors. Several compounds of the disclosure are specific or selective to alpha2B | 07/15/2008 |
| 7378433 | N-[4-(heteroarylmethyl)phenyl]-heteroarylamines The present invention is concerned with compounds of formula the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R1 is hydrogen, hydroxy, C1-... | 05/27/2008 |
| 7368579 | 1-substituted-4-nitroimidazole compound and process for producing the same The present invention relates to a 1-substituted-4-nitroimidazole compound represented by the general formula (1) or a salt thereof, (wherein R is a hydrogen atom, a lower alkoxy group-substituted lower alkyl group, a pheny... | 05/06/2008 |
| 7365210 | Method for the production of chiral imidazolidin-2-ones The invention relates to a process for preparing chiral imidazolidin-2-ones of the formula I in which R1 is C1-C8-alkyl, cyclohexyl, phenyl, a C1-C6-alkyl-... | 04/29/2008 |
| 7338976 | Heterocyclic esters or amides for vision and memory disorders This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic esters and amides. ... | 03/04/2008 |
| 7322297 | Cannelured frangible projectile and method of canneluring a frangible projectile A method of canneluring a frangible projectile includes the steps of rotating the projectile at a high speed, and cutting the cannelure into the projectile to form a frangible cannelured projectile. To ensure that the body is not damaged during cutting, the cutting ... | 01/29/2008 |
| 7323433 | R-(-)-1-[2-(7-chlorobenzo[b]thiopen-3-yl-methoxy)-2-(2,4-dichlorophenyl)-ethyl]-1H-imidazole The invention relates to R-(−)-1-[2-(7-Chloro-benzo[b]thiophen-3-yl-methoxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole and the salts thereof. The invention also relates to compositions thereof and their use either for treating fungal infections in humans and ani... | 01/29/2008 |
| 7317107 | Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity Imidazole compounds having adenosine deaminase inhibitory activity represented by the formula (I): wherein R1 is optionally substituted aryl or optionally substituted heteroaryl, R2 is lower alkyl; R3 is hydroxy or protected hydroxy;... | 01/08/2008 |
| 7304083 | 2-iminoimidazole derivatives (2) A 2-iminoimidazole derivative represented by the formula: {wherein R1, R2 and R3 represent hydrogen, optionally substituted C1-6 alkyl, etc.; R6 represents h... | 12/04/2007 |
| 7291642 | Bradykinin-B1 antagonists, process for their preparation and their use as medicaments The present invention provides bradykinin-B1 antagonists of the formula in which A, Ar, G, Q, R1 and R4 are as defined in claim 1, their enantiomers, their diastereomers, their mixtures and ... | 11/06/2007 |
| 7279497 | Benzopyran derivatives substituted with secondary amines including imidazole, their preparation and pharmaceutical compositions containing them The present invention relates to benzopyran derivatives substituted with secondary amines including imidazole, their preparation, and pharmaceutical compositions containing them. The present invention is pharmacologically useful for the treatment of cancer, rheumato... | 10/09/2007 |
| 7271270 | High affinity small molecule C5a receptor modulators This invention relates to low molecular weight, non-peptidic, non-peptidomimetic, organic molecules that act as modulators of mammalian complement C5a receptors, preferably ones that act as high affinity C5a receptor ligands and also to such ligands that act as anta... | 09/18/2007 |
| 7265150 | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders This invention relates to novel compositions and uses of N-heterocyclic carboxylic acids and carboxylic acid isosteres for treating a vision disorder, improving vision, treating memory impairment or enhancing memory performance in an animal. ... | 09/04/2007 |
| 7259263 | Method of synthesis of azole-containing amino acids The invention relates to methods of synthesizing 2-substituted azole compunds of formula (I): The invention is also relates to compounds of formula (I) and to intermediate compounds in the synthesis method. ... | 08/21/2007 |
| 7253200 | Imidazole compounds Imidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor expression, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions. | 08/07/2007 |
| 7253199 | Azole derivatives and pharmaceutical compositions containing them The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or prevent... | 08/07/2007 |
| 7244739 | Compounds and uses thereof in modulating amyloid beta Novel compounds, compositions, and kits are provided. Methods of modulating Aβ levels, and methods of treating a disease associated with aberrant Aβ levels are also provided. ... | 07/17/2007 |
| 7241787 | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments The invention relates to substituted N-cyclohexylheterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof, to processes for their preparation and to their use as medicaments. Compounds of the formula I, | 07/10/2007 |
| 7230114 | Intermediates for preparing neuraminidase inhibitor conjugates Compounds of formula (I), methods for their preparation and their use in the manufacture of neuraminidase inhibitor conjugates. Wherein R represents as carboxylic acid protecting group; P1 and P2 can be the same or different and are selected fr... | 06/12/2007 |
| 7211697 | Method for producing specific crystalline modifications of polmorphous substances The present invention pertains to a process for the production of a specific crystal modification of a polymorphic, organic substance by precipitation of the specific crystal modification from the aqueous solution of the salt of the polymorphic substances using ordi... | 05/01/2007 |
| 7202263 | N-heterocyclic derivatives as NOS inhibitors N-Heterocyclic derivatives of the following formula: where m, n, p, A1, R1, R2, R3 and R4 are described herein, as well as other N-heterocyclic derivatives, ... | 04/10/2007 |
| 7196108 | Bicyclic heterocycles for the treatment of diabetes and other diseases The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, and atherosclerosis. | 03/27/2007 |
| 7189755 | Pyrrolidine melanocortin-specific compounds Melanocortin receptor-specific pyrrolidine compounds having the structure: and stereoisomer and pharmaceutically acceptable salts thereof, where R1, R2, and R3 are as described in... | 03/13/2007 |
| 7157476 | Aminofurazan compounds useful as protein kinase inhibitors The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, ... | 01/02/2007 |
| 7143679 | Cannelured frangible cartridge and method of canneluring a frangible projectible A method of canneluring a frangible projectile includes the steps of rotating the projectile at a high speed, and cutting the cannelure into the projectile to form a frangible cannelured projectile. To ensure that the body is not damaged during cutting, the cutting ... | 12/05/2006 |
| 7129359 | Imidazolidinone compounds This invention relates to compounds of the following formula: in which R1, R2, A1, A2, X, Y, m, n, p, x and y are as defined herein, pharmaceutical compositions compris... | 10/31/2006 |
| 7118873 | Polynucleotides encoding cellular transporters and methods of use thereof This disclosure encompasses the Indy gene, polypeptides encoded by the Indy gene and fragments thereof. This disclosure also encompasses homologs of the Indy gene both from Drosophila and other organisms. In addition, this disclosure encompasses the use of In... | 10/10/2006 |
| 7115749 | Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents The present invention provides compounds of formula I wherein X and R1–R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorde... | 10/03/2006 |
| 7091221 | Partial ester of cellulose with nitrogenous carboxylic acid and process for producing the same According to the present invention, there are provided a novel partial ester of a nitrogenous carboxylic acid ester with cellulose, the partial ester being useful as an antibacterial agent, a flame retardant, etc., and a simple and convenient process for preparing t... | 08/15/2006 |
| 7049296 | Gamma-secretase inhibitors Urea derivatives of formula I are disclosed: The compounds are inhibitors of γ-secretase, and hence useful in the treatment or prevention of Alzheimer's Disease ... | 05/23/2006 |
| 7045535 | Compounds useful for inhibiting paramyxovirus neuraminidase Certain cyclic compounds are presented as well as their use for inhibiting paramyxovirus neuraminidase. The compounds are represented by the following formulas: ... | 05/16/2006 |
| 7041693 | Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE) The present application describes novel hydantoin derivatives of formula (I): or pharmaceutically acceptable salt or prodrug forms thereof, wherein L, Z0, R1, R4, R5, a... | 05/09/2006 |
| 7022727 | Crystalline drug form The present invention relates to a crystalline form of 6-[(2,2-diphenylethyl)amino]-9-(N-ethyl-β-D-ribofuranosyluronamide)-N-(2-{N′-[1-(2-pyridyl)-4-piperidyl]ureido}ethyl)-9H-purine-2-carboxamide and to a process for the preparation of, compositions containing a... | 04/04/2006 |
| 7002019 | Synthesis of indole thiazole compounds as ligands for the Ah receptor A method of synthesizing aromatic ketone compositions of formula I comprising the step of introducing a double bond into the 5 membered ring of the 4,5-dihydro-1,3-azoles moiety of formula II is disclosed. A method of synthesizing aromatic ketone compositions of for... | 02/21/2006 |
