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3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 8119814 | Aromatic hetrocyclic compound, organic light-emitting diode including organic layer comprising the aromatic hetrocyclic compound, and method of manufacturing the organic light-emitting diode The present invention provides an aromatic heterocyclic compound represented by Formula 1 below, an organic light-emitting diode including an organic layer comprising the aromatic heterocyclic compound, and a method of manufacturing the organic light-emitting diode:... | 02/21/2012 |
| 8088930 | Benzimidazole derivatives The invention is concerned with novel benzimidazole derivatives of formula (I) wherein A, n and R1 to R7 are as defined in the description and in the claims, as well as physiologically acceptable salts... | 01/03/2012 |
| 8063230 | Tris(N-aryl benzimidazole)benzenes and their use in electronic devices The present invention relates to tris(N-aryl-benzimidazole)benzene compounds of the formula: where R1-R6, Ar, m, n, p, q, r, and s are defined in the specification. Also provided are compositions compr... | 11/22/2011 |
| 7999117 | Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors The present invention relates to 1H-benzimidazole-4-carboxamides of formula (I), their preparation, and their use as inhibitors of the enzyme poly(ADP-ribose)polymerase for the preparation of drugs. ... | 08/16/2011 |
| 7777051 | Asymmetric benzimidazoles and related compounds as potassium channel modulators The present invention provides a genus of asymmetric benzimidazole compounds, methods and pharmaceut1cal compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods. ... | 08/17/2010 |
| 7687639 | Substituted benzimidazoles and imidazo-[4,5]-pyridines 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer. ... | 03/30/2010 |
| 7462724 | Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treat... | 12/09/2008 |
| 7414138 | Benzoxazole and benzodiazole UV-A sunscreens The present invention relates to 1,3-benzoxazole or benzodiazole UV-A sunscreens and to compositions, in particular topical compositions, containing the above UV-A sunscreens. ... | 08/19/2008 |
| 7345075 | 1,2 diarylbenzimidazoles and their pharmaceutical use Benzimidazoles of general formula I and the use of benzimidazole derivatives for the production of pharmaceutical agents for treatment and prophylaxis of diseases that are associated with a microglia activation are describe... | 03/18/2008 |
| 7304085 | Nitrogen-containing heteroaryl derivatives Disclosed are compounds, compositions and methods for treating Flaviviridae family virus infections. ... | 12/04/2007 |
| 7273939 | Methods of making tris(N-aryl benzimidazoles)benzenes and their use in electronic devices Provided are methods for preparing a compound of Formula I: where the method comprises the steps of: contacting a compound of Formula II: | 09/25/2007 |
| 7271261 | Substituted benzimidazoles and imidazo-[4,5]-pyridines 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer. ... | 09/18/2007 |
| 7244847 | Benzimidazole compounds The present invention is directed to novel benzimidazoles according to representative structures I and II, and their derivatives that possess antibacterial activity. This invention is also directed to compositions including the benzimidazole derivatives, and methods... | 07/17/2007 |
| 7208143 | Antiperspirant compositions What is described herein is an antiperspirant composition including an active antiperspirant ingredient, and a phenylethyl, benzyl or substituted benzyl ester as additive therein, which is an aryl carboxylic ester of 2-phenylethyl alcohol, 1-phenylethyl alcohol or b... | 04/24/2007 |
| 7179832 | Glycogen synthase kinase 3β inhibitor, composition and process for the preparation thereof Novel compounds having hydroxybenzoimidazole carboxylic amide are useful for inhibiting glycogen synthase kinase 3β(GSK-3β). ... | 02/20/2007 |
| 7151114 | Use of substituted 2-phenylbenzimidazoles as medicaments The present invention relates to the use of a substituted 2-phenylbenzimidazole of formula I wherein R1, R2, R3, R4, R5 and m have the meanings given in the ... | 12/19/2006 |
| 7132440 | Substituted benzimidazoles and imidazo-[4,5]-pyridines 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer. ... | 11/07/2006 |
| 7132097 | Sunscreen compositions A sunscreen composition which includes at least one UV-B active ingredient therein, optionally with a UV-A active, and a phenylethyl or benzyl ester in an amount sufficient to boost the SPF rating of the UV-B active therein. ... | 11/07/2006 |
| 6919366 | Benzimidazole derivatives as modulators of IgE This invention relates to a family of benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy, asthma, or any diseases where IgE is pathogenic. ... | 07/19/2005 |
| 6888005 | 2-phenylbenzimidazole-5-sulphonic acid from isolated 3,4-diaminobenzenesulphonic acid and use thereof in cosmetic preparations A process for the preparation of 2-phenylbenzimidazole-5-sulphonic acid, characterized in that 3,4-diaminobenzenesulphonic acid is reacted at a pH between 4 and 7 in aqueous solution with 0.9 to 1.5 mol of benzaldehyde per mole of 3,4-diaminobenzenesulphonic acid an... | 05/03/2005 |
| 6878469 | Material for transporting electrons and organic electroluminescent display using the same Novel materials for electron injection/transportation and emitting layers can greatly improve the stability of an organic electroluminescent display. Electroluminescent displays incorporating these materials produce blue light at low voltage levels. These novel orga... | 04/12/2005 |
| 6855714 | 1-alkyl-2-aryl-benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives The invention relates to novel benzimidazole derivatives with general formula I, whereby radicals R1, R2, R3, A, B and Y have the meanings that are indicated in the description and the claims, the use of these compounds for the produ... | 02/15/2005 |
| 6696437 | Heterocyclically substituted benzimidazoles, the production and application thereof The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.... | 02/24/2004 |
| 6660742 | Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins The present invention relates to novel achiral seco-analogues of DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II, III, IV and V: ##STR1## wherein X is a good leaving group, such as... | 12/09/2003 |
| 6649642 | Succinate derivative compounds useful as cysteine protease inhibitors Disclosed are novel succinate derivative compounds of the formula(I)/(Ia): ##STR1## wherein R1, R2, R3, R4, R5, R6, R7, X and A are defined herein. The compounds are useful as inhibitors of cysteine proteases. Also disclosed are methods of using and metho... | 11/18/2003 |
| 6593476 | Process for the preparation of UV filter substances The present invention relates to a preparation process for 2-arylbenzimidazolesulfonic acids of the formula I: ##STR1## Ar is a substituted or unsubstituted phenyl or naphthyl radical and R is a C1-8 -alkyl or C1-8 -alkoxy radical. n... | 07/15/2003 |
| 6541499 | Antithrombotic agents The invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts, as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula (I), and the ... | 04/01/2003 |
| 6465484 | Angiogenesis inhibitors The present invention relates to compounds which inhibit tyrosine kinase enzymes, compositions which contain tyrosine kinase inhibiting compounds and methods of using tyrosine kinase inhibitors to treat tryrosine kinase-dependent diseases/conditions such ... | 10/15/2002 |
| 6440401 | 2-phenyl-benzimidazolesulfonic acids as UV-B filters Disclosed is a 2-phenyl-benzimidazolesulfonic acid according to the formula ##STR1## in which n is 0, 1 or 2 and m is 2 or 3, R1, R2, R3, R4 and R5, are each a radical such as H, C1-8 -alkyl, C1-8 -alkoxy, hydroxyl, sulfate, nitro, F, Cl,... | 08/27/2002 |
| 6387938 | Benzimidazole derivatives This invention provides novel benzimidazole derivatives represented by the formula (I); a process for producing the same; a drug containing at least one of such compounds as its active ingredient, in particular, a drug for preventing and/or treating disea... | 05/14/2002 |
| 6369235 | Substituted benzimidazoles, and methods of use thereof, for the inhibition of HIV reverse transcription and for the treatment of HIV infection The present invention provides compositions and methods for the treatment of HIV infection. In particular, the present invention provides non-nucleoside inhibitors of reverse transcriptase (RT), as well as methods to treat HIV infection using these non-nu... | 04/09/2002 |
| 6316620 | Electronically tuned ligands A new class of chiral bidentate ligands to transition metals is disclosed which compounds have the following structure: ##STR1## wherein the substituents are as defined herein.... | 11/13/2001 |
| 6310082 | Benzimidazole compounds Benzimidazole-4-carboxamide compounds (I) which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC 2.4.2.30), and which thereby can provide useful therapeutic compounds for use in conjunction with DNA-dama... | 10/30/2001 |
| 6271390 | Suppression of the IgE-dependent allergic response by benzimidazole analogs The present invention is directed to small molecule inhibitors of the IgE response to allergens which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.... | 08/07/2001 |
| 6251689 | Methods for the solid phase synthesis of combinatorial libraries of benzimidazoles benzoxazoles benzothiazoles and derivatives thereof The present invention provides an efficient and versatile method for the synthesis and screening of combinatorial libraries of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof. In order to expedite the synthesis of large arrays of com... | 06/26/2001 |
| 6222044 | Process for making 2-aryl benz (ox, thi, imid) azoles and 2-aminoaryl aminobenz (ox, thi, imid) azoles 2-(aryl)-benz(ox, thi, imid)azoles are prepared by reacting an aromatic aldehyde with hydroxylamine to form an aromatic aldehyde oxime, halogenating the oxime to form an aromatic hydroxamoyl halide, and then reacting this halide with certain aromatic amin... | 04/24/2001 |
| 6194396 | Benzimidazole compounds as bradykinin antagonists This invention relates to a heterocyclic compound of the formula ##STR1## wherein a group of the formula: ##STR2## is a group of the formula ##STR3## X is O, S or N-R5, R1 is lower alkyl, etc., R5 is hydrogen, lower alkyl,... | 02/27/2001 |
| 6184235 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists The present invention relates to novel compounds and medical methods of treatment of inflammation, atherosclerosis, restenosis, and immune disorders especially those associated with lymphocyte or monocyte accumulation such as arthritis and transplant reje... | 02/06/2001 |
| 6162804 | Tyrosine kinase inhibitors The present invention relates to benzinidazole compounds which inhibit tyrosine kinase enzymes, compositions which contain tyrosine kinase inhibiting compounds and methods of using tyrosine kinase inhibitors to treat tyrosine kinase-dependent diseases/con... | 12/19/2000 |
| 6100283 | Benzimidazole compounds Benzimidazole-4-carboxamide compounds (I) which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC 2.4.2.30), and which thereby can provide useful therapeutic compounds for use in conjunction with DNA-dama... | 08/08/2000 |
