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| Number | Title | Issue Date |
| 7351731 | Azole derivatives and methods for making the same The present invention is broadly directed to azole derivatives that exhibit antifungal activity and methods for making the same. In one aspect, the invention includes carboxylic acid and phosphate ester derivatives of fluconazole that exhibit antifungal activity. In... | 04/01/2008 |
| 7230023 | Water-soluble triazole fungicide A triazole compound of the formula (I) or a pharmacologically salt thereof: wherein X represents a group of formula X—OH which has antifungal activity, L represents an -(adjacently substituted C6-C | 06/12/2007 |
| 7169929 | Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor The present invention relates to a novel diaryl 1,2,4-triazole derivative of the following formula (1) as a highly selective cyclooxygenase-2 inhibitor, wherein R1, R2, R3, R4, R5, W and A is as defined in this ... | 01/30/2007 |
| 6969697 | Substituted benzoylcyclohexenones The invention relates to novel substituted benzoylcyclohexenones of the formula (I), in which n, A, R1, R2, R3, R4, Y and Z are each as defined in the descriptio... | 11/29/2005 |
| 6919299 | Synergistic herbicidal compositions Herbicidal compositions comprising A) 2-[2-chloro-3-(2,2,2-trifluoroethoxymethyl)-4-methylsulfonyl-benzoyl]cyclohexane-1,3-dione and B) at least one compound from the group consisting of ethoxysulfuron, flumetsulam... | 07/19/2005 |
| 6844444 | 1H-1,2,4-triazole-5-yl-acetic ester compound There is disclosed a 1H-pyrrole-[1,2-b][1,2,4]triazole compound represented by formula (I): wherein R is an alkyl group; R1, R2, R3, R1′, R2′, and R3 | 01/18/2005 |
| 6803380 | 5-aryl-1h-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them 5-aryl-1H-triazole compounds of the formula are potent and selective COX-2 inhibitors. The invention further relates to pharmaceutical compositions containing these compounds. ... | 10/12/2004 |
| 6723742 | Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I in which R1-R5 are as defined in the description. The compounds have useful pharmaceutical properties and are particularly activ... | 04/20/2004 |
| 6653330 | Amide-type triazole compounds A compound of formula (I) or a pharmacologically acceptable prodrug or salt thereof which exhibits excellent antifungal activity: ##STR1## wherein Ar1 represents a phenyl group or the like; Ar2 represents a phenylene group or the lik... | 11/25/2003 |
| 6566383 | Sulfonyltriazol derivatives and their use for combating micro-organisms Sulphonyltriazoles of the formula ##STR1## wherein Hal, R1, R2 are as defined in the specification are provided along with a process for preparing these compounds and a process using these compounds to control the growth of microorga... | 05/20/2003 |
| 6528500 | Azole derivatives or salts thereof Described is an azole derivative represented by the following formula (1): ##STR1## wherein, R1 represents a substituted phenyl group, R2 and R3 each represents a fluorine atom, an alkyl group or the like, and R4 ... | 03/04/2003 |
| 6486159 | Water soluble prodrugs of azole compounds Water-soluble prodrugs of triazole antifungal compounds having a secondary or tertiary hydroxy group are provided. More particularly, new water-soluble triazole antifungal compounds are provided having the general formula ##STR1## wherein A is the no... | 11/26/2002 |
| 6465504 | Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I ##STR1## in which R1 -R5 are as defined in the description. The compounds have useful pharmaceutical properties and are particularly active as iron chelators. They... | 10/15/2002 |
| 6440899 | Cyclohexenonedioxothiochromanoyl derivatives Cyclohexenonedioxothiochromanoyl derivatives of the formula I ##STR1## where X is oxygen, sulfur, S.dbd.O, S(.dbd.O)2, CR4 R5, C.dbd.O or C.dbd.NR6, the other substituents are as defined in the specification, an... | 08/27/2002 |
| 6359141 | Water soluble prodrugs of azole compounds Water-soluble prodrugs of triazole antifungal compounds having a secondary or tertiary hydroxy group are provided. More particularly, new water-soluble triazole antifungal compounds are provided having the general formula ##STR1## wherein A is the no... | 03/19/2002 |
| 6300357 | Triazole antifungal agent A triazole compound having the formula: ##STR1## wherein Ar1 represents a phenyl group which may be substituted, Ar2 represents a heterocyclic group which may be substituted, R0 represents a hydrogen atom or a lower alkyl;... | 10/09/2001 |
| 6265584 | Water soluble prodrugs of azole compounds Water-soluble prodrugs of triazole antifungal compounds having a secondary or tertiary hydroxy group are provided. More particularly, new water-soluble triazole antifungal compounds are provided having the general formula ##STR1## wherein A is the no... | 07/24/2001 |
| 6262099 | 3-(substituted phenyl)-5-(substituted cyclopropyl)-1,2,4-triazole compounds 3-(Substituted phenyl)-5-(substituted cyclopropyl)-1,2,4-triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and methods of ... | 07/17/2001 |
| 6194584 | Process for preparing triazole antimycotic compounds Process for the preparation of a compound of formula (VII) wherein R1 is Cl, F or CF3 ; R2 is H, Cl, F or CF3 ; and R3 is C1-4 alkyl; characterized in that an olefin of formula (II) is epox... | 02/27/2001 |
| 6114539 | Mercapto-imidazolyl derivatives The present invention provides mercapto-imidazolyl compounds, and the acid addition salts and metal salt complexes thereof; a process for their preparation; and a method for their use as microbicides.... | 09/05/2000 |
| 6103909 | Azole compounds endowed with antimycotic activity for human and veterinary use Compounds of formula ##STR1## wherein R1 is chloro, fluoro, bromo or trifluoromethyl; R2 is hydrogen, chloro , fluoro, bromo or trifluoromethyl; Z is CH or N; R3, R4 and R5, which are the same or different... | 08/15/2000 |
| 6083968 | Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient Described is a triazole derivative represented by the formula (1): ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently re... | 07/04/2000 |
| 6057353 | Triazolyl-mercaptides and their use as microbicides Triazoyl mercaptides of the formula (I) ##STR1## in which M is an alkaline metal cation, an equivalent of an alkaline earth cation, an equivalent of a copper zinc, iron or nickel cation or an ammonium cation and R1 is various radicals, a p... | 05/02/2000 |
| 6048984 | Intermediates to herbicidal 2-benzoylcyclohexane-1,3-diones and related compounds The invention relates to compounds of formula (I): and to their use as herbicides, and to intermediates useful in their preparation.... | 04/11/2000 |
| 6040325 | Triazole derivative or salt thereof preparation process thereof, and pharmaceutical containing said compound as an effective ingredient Described is a triazole derivative represented by the formula (1): wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represents a hyd... | 03/21/2000 |
| 6022937 | Polyether polyols based on triazole group containing compounds and a process for their production This invention relates to novel polyether polyols and to a process for their production. These polyether polyols are prepared by forming a polyhydroxyl group containing component in a first step by the reaction of a triazole-group containing compound with... | 02/08/2000 |
| 6008239 | Triazole derivative or salt thereof Described is a triazole derivative represented by the formula (1): ##STR1## wherein R1 represents a lower alkyl group or an aralkyl group, R2 represents a hydrogen atom, a lower alkyl group, an aralkyl group or an acyl group, X | 12/28/1999 |
| 5981560 | Triazole antifungal agents An antifungal compound of formula (I): ##STR1## or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of either entity, wherein X is CH or N; R1 is phenyl substituted with 1 to 3 substituents each independ... | 11/09/1999 |
| 5977152 | Triazole antifungal agent A triazole compound having the formula: ##STR1## wherein Ar1 represents an optionally substituted phenyl, Ar2 represents an optionally substituted phenyl, R0 represents a hydrogen atom or a lower alkyl; R1 ... | 11/02/1999 |
| 5977376 | Herbicidal 2-benzoylcyclohexane-1,3-diones and related compounds The invention relates to compounds of formula (I): ##STR1## and to their use as herbicides.... | 11/02/1999 |
| 5945438 | Triazole derivative and pharmaceutical comprising the same as an effective ingredient Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) ... | 08/31/1999 |
| 5939448 | Triazole derivative or salt thereof Described is a triazole derivative represented by the formula (1): wherein R represents a hydrogen atom, an alkyl group, an aralkyl group or an acyl group, n stands for 0 to 2 and m stands for 1 to 5 or salt thereof, and a pharmaceutical containing the de... | 08/17/1999 |
| 5912355 | Chiral synthesis of tertiary alcohols with a hydrolase Method of preparing an optically active compound of formula, wherein R and R1 are independently alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, cycloalkyl, aryl, aralkyl, a heterocyclic group or a C1 -C4 alkyl-heterocycle, e... | 06/15/1999 |
| 5872258 | Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof A process for making Fluconazole is provided comprising carrying out the following scheme of reaction: ##STR1##... | 02/16/1999 |
| 5869512 | Azole compounds with antimycotic activity for human and veterinary use Compounds of formula ##STR1## wherein R1 is chloro, fluoro, bromo or trifluoromethyl; R2 is hydrogen, chloro, fluoro, bromo or trifluoromethyl; Z is CH or N; R3, R4 and R5, which are the same or different,... | 02/09/1999 |
| 5856350 | 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants This invention relates to the treatment of depression by administration of novel 3-(Rn -phenyl)-1,4-dialkyl-1,2,4-triazolium salts of the formula ##STR1## wherein R is halogen, trifluoromethyl, C1-4 lower alkyl or C1-4 | 01/05/1999 |
| 5840894 | Preparation of 1,2,4-triazolium salts and 1,2,4-triazolines A process for the preparation of 1,2,4-triazolium salts Ia ##STR1## where R1, and R2 and R3 are C-organic radicals, it being possible for R2 and R3 to be connected to give a 5- to 8-membered ring... | 11/24/1998 |
| 5814651 | Catechol diethers as selective PDEIV inhibitors This invention relates to 4-substituted catechol diether compounds which are selective inhibitors of phosphodiesterase (PDE) type IV. The compounds of the present invention are useful in inhibiting PDEIV and in the treatment of AIDS, asthma, br... | 09/29/1998 |
| 5786375 | Hydroxyethyl-azolyl derivatives Hydroxyethyl-azolyl derivative of the formula (I): ##STR1## in which x represents hydrogen, halogen, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms, z represents halogen, alkyl having 1 to 4 carbon atoms, halogenoalkyl having 1... | 07/28/1998 |
| 5760067 | Halogen alkenyl azolyl microbicides Novel halogenoalkenyl-azolyl derivatives of the formula ##STR1## in which R1 represents optionally substituted alkyl, optionally substituted alkenyl, optionally substituted cycloalkyl, optionally substituted aryl or represents optionally ... | 06/02/1998 |
