...that the first rickshaw was invented in 1869 by an American Baptist minister, the Rev. E. Jonathan Scobie, to transport his invalid wife around the streets of Yokohama?
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| Number | Title | Issue Date |
| 7135475 | Amide substituted xanthine derivatives The present invention is a 1,3,8 substituted xanthine derivative of formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are as defined in the specificat... | 11/14/2006 |
| 6987112 | Organic compound having cyano group and insecticides/miticides The present invention is directed to compounds represented by Formula (1); wherein A, R, X, Y and n are as defined in the description, the salts thereof, and insecticide/acaricide compositions characterized by comprisi... | 01/17/2006 |
| 6649568 | Brassinosteroid biosynthesis inhibitor Compounds represented by the following formula (I): ##STR1## wherein R1 represents a lower alkenyl group or a phenyl group which may be substituted, R2 and R3 independently represent a phenyl group which may be substituted... | 11/18/2003 |
| 6395367 | Pentacyclic anion salts or tetrazapentalene derivatives and their uses as ionic conducting materials The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention includes an anionic portion combined with at least one cationic portion Mm+ in sufficient numbers to ensure overall e... | 05/28/2002 |
| 6359141 | Water soluble prodrugs of azole compounds Water-soluble prodrugs of triazole antifungal compounds having a secondary or tertiary hydroxy group are provided. More particularly, new water-soluble triazole antifungal compounds are provided having the general formula ##STR1## wherein A is the no... | 03/19/2002 |
| 6265584 | Water soluble prodrugs of azole compounds Water-soluble prodrugs of triazole antifungal compounds having a secondary or tertiary hydroxy group are provided. More particularly, new water-soluble triazole antifungal compounds are provided having the general formula ##STR1## wherein A is the no... | 07/24/2001 |
| 6159938 | Serine protease inhibitors comprising -keto heterocycles Provided are methods of inhibiting the activity of a serine protease using protease inhibitors that include an alpha-keto heterocycle in their structure. The methods are useful in the treatment of ischemic heart or treatment of symptoms associated with bl... | 12/12/2000 |
| 6063928 | 5-lipoxygenase inhibitors Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: ##STR1## and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyr... | 05/16/2000 |
| 5922867 | Method and compositions for the synthesis of dioxolane nucleosides with ଲ configuration The present invention relates to methods and compositions for preparing biologically important nucleoside analogues containing 1,3-dioxolane sugar rings. In particular, this invention relates to the stereoselective synthesis of the beta (cis) isomer by gl... | 07/13/1999 |
| 5874585 | Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase.... | 02/23/1999 |
| 5869508 | 1,2,3-Benzothiadiazole derivatives Novel 1,2,3-benzothiadiazole derivatives of the formula ##STR1## in which Het has the meanings set forth in the specification, and addition products thereof with an acid or metal salt are very effective for the control of undesired microorganisms. Novel i... | 02/09/1999 |
| 5840894 | Preparation of 1,2,4-triazolium salts and 1,2,4-triazolines A process for the preparation of 1,2,4-triazolium salts Ia ##STR1## where R1, and R2 and R3 are C-organic radicals, it being possible for R2 and R3 to be connected to give a 5- to 8-membered ring... | 11/24/1998 |
| 5602196 | Bisphenol ester derivatives Stabilisers of formula I ##STR1## wherein R1 and R2 may be C1 -C5 alkyl, the substituents R3 to R8 may be hydrogen, the variable n may be 1 or 2, and, when n is 1, A may be an alkoxy r... | 02/11/1997 |
| 5530117 | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines The disclosure is drawn to novel 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds. These compounds are useful to treat infections caused by a wide spectrum of bacterial organisms, including those which are resistant to tetracyc... | 06/25/1996 |
| 5476845 | Use of phosphoric esters as crystallization inhibitors A new process for preventing the crystallization of certain azole derivatives in the spray equipment upon spraying mixtures containing A) certain azole derivatives which have a tendency to crystallize and B) if appropriate one or more other active compounds and add... | 12/19/1995 |
| 5369118 | N-alkyl-lactams as crystallization inhibitors In the spraying of an aqueous liquor comprising at least one of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-yl-methyl)-pentan-3-ol and 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-ol, the improvement which comprises including in ... | 11/29/1994 |
| 5366984 | Methyl -arylacrylates substituted by a heterocyclic radical and their use Methyl -arylacrylates substituted by a heterocyclic radical and having the general formula ##STR1## where R is alkyl, alkenyl, haloalkyl, cycloalkyl, alkoxy, alkylcarbonyl, alkoxycarbonyl, halogen or aryl, the aromatic ring being unsubstituted... | 11/22/1994 |
| 5250555 | 1-halo-1-azolylmethane derivatives and fungicides containing these 1-Halo-1-azolylmethane derivatives of the formula ##STR1## where A and R are each alkyl, benzyl, benzoyl, acyl, biphenylyl, naphthyl, hetaryl or phenyl, it being possible for each of these radicals to be substituted; D is Cl or Br, X is CH or N, and ... | 10/05/1993 |
| 5225550 | Process for the preparation of substituted acyclic nucleosides, and intermediates occurring therein It is possible, by using symmetrical formaldehyde acetals of the formula ##STR1## in which the substituents R1 -R3 have the specified meanings, advantageously to introduce the substituent ##STR2## into nitrogen-containing h... | 07/06/1993 |
| 5206225 | Alkylcarboxylic acid dimethylamides as crystallization inhibitors Crystallization of active material in spraying an aqueous solution of one of ##STR1## and is prevented by incorporation therein of an alkylcarboxylic acid dimethylamide of the formula ##STR2## in which R represents alkyl having 5 to 19 carb... | 04/27/1993 |
| 5199969 | Azolylethane derivatives and fungicides and growth regulators containing them Azolylethane derivatives of the general formula I ##STR1## where A and Z are each alkyl, phenyl, biphenyl, naphthyl, benzyl, cycloalkyl or cycloalkenyl, these radicals being substituted or unsubstituted, D is alkoxy, amino, mercapto, thiophenyl, amin... | 04/06/1993 |
| 5187182 | N-phenoxyphenoxymethyl-triazoles and a method for controlling pests N-substituted azoles of the formula I ##STR1## where R1,R2, R3 are each hydrogen, halogen, C1 -C8 -alkyl, C1 -C8 -alkoxy, C1 -C4 -haloalkyl, C1 | 02/16/1993 |
| 5140036 | 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders A class of 1,3,5-trisubstituted-1,2,4-triazole compounds is described for use in treatment of circulatory disorders. Compounds of particular interest are angiotensin II antagonists of the formula ##STR1## wherein m is one; wherein R1 is se... | 08/18/1992 |
| 5128357 | 1-alkoxy-1-azolylmethyloxiranes and the use thereof as crop protection agents 1-Alkoxy-1-azolylmethyloxiranes of the general ##STR1## where R1 and R2 are identical or different and each is C1 -C8 -alkyl, C3 -C8 -cycloalkyl, C5 -C8 -cycloalk... | 07/07/1992 |
| 5124344 | Compounds containing triazole groups and use thereof as fungicides The invention relates to compounds of formula: ##STR1## A is the group (Y)n Ph--(CH2)m where Ph is a phenyl nucleus and m=0 or 1, preferably 0, Y is a halogen atom or a cyano or nitro group or an optionally halogenated ... | 06/23/1992 |
| 5101059 | Amino acid protecting groups This invention relates to compounds of the formula a compound of the formula ##STR1## wherein X is O, CR7 R8, S or NR9 wherein R7 and R8 are independently hydrogen, or lower alkyl, and R9 | 03/31/1992 |
| 5093346 | Substituted 1,2,4-triazole angiotensin II antagonists Substituted pyrroles, pyrazoles and triazoles such as ##STR1## and their pharmaceutically suitable salts are useful as antihypertensive agents and for treatment of congestive heart failure.... | 03/03/1992 |
| 5015651 | Treatment of hypertension with 1,2,4-angiotensin II antagonists Substituted pyrroles, pyrazoles and traizoles such as ##STR1## and their pharmaceutically suitable salts are useful as antihypertensive agents and for treatment of congestive heart failure.... | 05/14/1991 |
| 5013854 | Process for preparing acid halides An improved process for preparing trialkylsilyl ester and acid halide derivatives of carboxylic acids is provided along with novel trialkylsilyl ester intermediates of 2-(2-furyl)-2-methoximinoacetic acid.... | 05/07/1991 |
| 4970320 | Preparation of phenoxy-triazolyl-pinacol-ones X represents a halogen, phenyl, phenoxy or halophenoxy moiety, and n is an integer of from 0 to 5, is produced by reacting 1,2,4-triazole with an -halo--phenoxy compound of the formula ##STR2## in which Y represents Br or Cl, in the presenc... | 11/13/1990 |
| 4942244 | Diastereomeric triazolyl glycol ethers-fungicides and growth regulators Diastereomers of the formula ##STR1## Where R1 is hydrogen, alkyl, alkenyl, alkynyl or benzyl, R2 is a alkyl or alkenyl, R3 is alkyl or benzyl, and the asymmetric centers of the molecular have (a) an RR or SS or (b) a... | 07/17/1990 |
| 4931581 | Process and a composition for immunizing plants against diseases A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula ##STR1## in which: X is hydrogen, halogen, hydroxy, methyl, methoxy, HOOC or MOOC; Y is hydrogen, halo... | 06/05/1990 |
| 4925476 | Azole hemiaminal derivatives and their use as nitrification inhibitors Nitrification inhibitors contain azole hemiaminal derivatives of the formula ##STR1## where R1 and R2 are each hydrogen, alkyl, aryl or halogen, R3 is alkyl, cycloalkyl, alkoxy, alkenyl, alkynyl, styryl, aryl, he... | 05/15/1990 |
| 4917720 | Fungicidal and plant-growth regulating azolyl ether ketones and alcohols Azolyl ether ketones and alcohols of the formula ##STR1## in which R1 and R2 each independently represents alkyl with more than one carbon atom, or R1 represents dichloromethyl, trichloromethyl, chlorovinyl or dichlor... | 04/17/1990 |
| 4895586 | Triazolyl glycol ethers, fungicides and bioregulators -triazolyl glycol ethers of the formula I ##STR1## where R1 is alkyl, alkoxy, halogen or phenyl, R2 and R3 are each hydrogen or alkyl, R4 is alkyl or unsubstituted or substituted phenyl, Z is ##STR2## ... | 01/23/1990 |
| 4878939 | Fungicidal and plant-growth regulating azolyl ether ketones and alcohols Azolyl ether ketones and alcohols of the formula ##STR1## in which R1 and R2 each independently represents alkyl with more than one carbon atom, or R1 represents dichloromethyl, trichloromethyl, chlorovinyl or dichlor... | 11/07/1989 |
| 4871389 | Heterocyclic compounds A compound having the general formula: ##STR1## and stereoisomers thereof, wherein R1 is alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, all having up to 8 carbon atoms; or is aryl, aralkyl or heterocyclyl, any of which may be optiona... | 10/03/1989 |
| 4833252 | Herbicidal sulfonylureas Substituted N-phenylsulfonyl-N'-pyrimidinylureas and N-phenylsulfonyl-N'-triazinylureas of the general formula ##STR1## and the salts thereof with amines, alkali metal bases or alkaline earth metal bases, or with quaternary ammonium bases, have good ... | 05/23/1989 |
| 4828603 | Herbicidal oxatricyclo-nonane ethers The present invention relates to novel tricyclo ether derivative compounds, to compositions containing these ether derivative compounds, and to methods of using these compounds or compositions to control the growth of undesired vegetation.... | 05/09/1989 |
| 4806542 | Isohexide pyrimidines triazines, triazoles and imidazoles useful as cytostatic Isohexide nucleosides of the formula I ##STR1## in which R and B have the meaning given in the description, processes for their preparation and their use as medicaments, in particular as cytostatics, virustatics and immunostimulants.... | 02/21/1989 |