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| Number | Title | Issue Date |
| 7511152 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 03/31/2009 |
| 7402606 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle ... | 07/22/2008 |
| 7388006 | Non-steroidal progesting The present invention relates to non-steroidal progestins of the general formula (I) wherein R1 and R2 are independently of each other —H or —F, R3 is —CH | 06/17/2008 |
| 7361767 | N-sulfonyldicarboximide containing tethering compounds Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The s... | 04/22/2008 |
| 7288583 | Method of content protection with durable UV absorbers The contents of clear or lightly colored plastic containers or films are protected from ultraviolet radiation by the incorporation of certain UV absorbers of the class of durable benzotriazoles and tris-aryl-s-triazines in the container or film. Contents to be prote... | 10/30/2007 |
| 7250436 | Indazole-aminoacetonitrile derivatives having special pesticidal activity The invention relates to compounds of the general formula wherein Ar1, Ar2, R4, R5, R6, R7, R8, W, X, a and b have the significances gi... | 07/31/2007 |
| 7157586 | Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith Benzotriazole UV absorbers substituted with a ultra long ester or amide moiety wherein the ester or amide group is a hydrocarbyl group of 25 to 100 carbon atoms or is a group of alkyl of 25 to 100 carbon atoms interrupted by 5 to 39 oxygen atoms and terminated with ... | 01/02/2007 |
| 7097789 | Thermoplastic containers exhibiting excellent protection to various ultraviolet susceptible compounds Novel thermoplastic articles that contain novel ultraviolet absorbing compounds that are liquid in nature, are extremely low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat any discoloring wi... | 08/29/2006 |
| 7084280 | Benzotriazol-1-yl-aminoacetonitrile compounds and their use in the control of parasite disease The invention relates to benzotriazol-1-yl-aminoacetonitrile compounds and optionally the enantiomers thereof. The active ingredients have advantageous pesticidal properties. They are especially suitable for controlling parasites on warm-blooded animals. ... | 08/01/2006 |
| 7019003 | Peptide deformylase inhibitors Novel PDF inhibitors and novel methods for their use are provided. ... | 03/28/2006 |
| 7014797 | Low-color ultraviolet absorbers for high UV wavelength protection applications Novel ultraviolet absorbing compounds that are liquid in nature, are extremely low in color and are highly effective in providing protection in wavelength ranges for which previous attempts at low-color ultraviolet absorbers have failed are provided herein. Such com... | 03/21/2006 |
| 6949556 | Acylated 1,2,3,4-tetrahydronaphthyl amines and their use as pharmaceutical agents The present invention relates to compounds of general formula (I), wherein R1-R4 have the meanings given in the specification, A is CH2, CHOH or CH—(C1-C3-alkyl), B and C a... | 09/27/2005 |
| 6939967 | Non-proteinogenic L-amino acids Process for production of non-proteinogenic L-amino acids by direct fermentation of a microorganism strain known per se having a deregulated cysteine metabolism in a manner known per se, which comprises adding, during the fermentation, a nucleophilic compound to the... | 09/06/2005 |
| 6930136 | Adhesion promoters containing benzotriazoles Benzotriazole adducts contain a benzotriazole segment and a segment with a curable and polymerizable functionality, or an adhesion promoting functionality, particularly suitable for use on metal substrates or in adhesive, sealant or coating compositions for use in p... | 08/16/2005 |
| 6869913 | Pyridazin-3-one derivatives, their use and intermediates for their production Novel pyridazin-3-one derivatives of formula [1] are provided, which are useful as active ingredients of herbicides, wherein R1 is haloalkyl; R2 and R3 are hydrogen, alkyl, haloalkyl, o... | 03/22/2005 |
| 6800676 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith 2H-Benzotriazole UV absorbers substituted at the 3-position and/or the 5-position of the phenyl ring by a phenyl moiety which is substituted by a heteroatom are particularly photostable in automotive coatings, and are of low color and exhibit low volatility in therm... | 10/05/2004 |
| 6790955 | Processes for the preparation of aminophenylsulfonyl-ureas and intermediate products for the processes The invention relates to the preparation of compounds (I) in which A═H or acyl and R1, R2, R3, R, n, X, Y and Z are as defined in claim 1 by halogenation and rearrangement of compounds ... | 09/14/2004 |
| 6703510 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof Compounds of formula I or II ##STR1## where R is an aryl moiety, such as phenyl, naphthyl or biphenylyl, or is phenyl substituted by one or more trifluoromethyl, bromo or cyano, and E1 and E2 are independently hydrogen, alkyl, aralky... | 03/09/2004 |
| 6664395 | Benzotriazoles anti-inflammatory compounds The present invention relates to novel benzotriazoles of the formula I ##STR1## wherein Het is an optionally substituted 5-membered heterocycle containing one to two heteroatoms selected from nitrogen, sulfur and oxygen wherein at least one of said hetero... | 12/16/2003 |
| 6653484 | Polyoxyalkylene substituted and bridged benzotriazole derivatives Triazine, benzotriazole and benzophenone derivatives which are substituted or bridged with polyoxyalkylene groups, according to claim 1, and their use as UV absorbers, especially in photographic materials, in inks, including inkjet inks and printing inks,... | 11/25/2003 |
| 6653308 | 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinas... | 11/25/2003 |
| 6562972 | Method for preparing heterocyclic-carboxylic acids The present invention relates to a method for preparing quinoxaline-5- and 6-carboxylic acids. The method comprises contacting an aqueous alkaline suspension of a 5- or 6-halomethyl quinoxaline with oxygen in the presence of a transition metal catalyst, t... | 05/13/2003 |
| 6559308 | Method for preparing heterocyclic-carboxylic acids The present invention relates to a method for preparing quinoxaline-5- and 6-carboxylic acids. The method comprises contacting an aqueous suspension of a 5- or 6-hydroxymethyl quinoxaline with oxygen in the presence of a transition metal catalyst, to form... | 05/06/2003 |
| 6548525 | Nitrogen containing heteroaromatics with ortho-substituted P1's as factor Xa inhibitors The present application describes nitrogen containing heteroaromatics with ortho-substituted P1's and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D is substituted ortho ... | 04/15/2003 |
| 6548678 | Method for producing 5-phenoxycarbonylbenzotriazole Disclosed is a method for producing 5-phenoxycarbonylbenzotriazole (I): ##STR1## by reacting 1H-benzotriazole-5-carboxylic acid (II): ##STR2## with diphenyl carbonate (III): ##STR3##... | 04/15/2003 |
| 6541423 | 4-(3',4'-heterocyclyl benzoyl) pyrazoles as herbicidal agents The invention relates to pyrazolyl derivatives of benzo-condensated, unsaturated 5-membered nitrogen heterocycles of the general formula (I), wherein X represents N or a group C--R3 ; Y is O, S, SO, SO2 or NR4 or X--Y is S... | 04/01/2003 |
| 6515124 | Dehydroamino acids Aromatic dehydroamino acids are disclosed that are active as LFA-1 arnagonists This activity enables these compounds to prevent inflammation which is a consequence of T cell activation and accordingly reduce or eliminate inflammatory skin disease psoriasi... | 02/04/2003 |
| 6500851 | Antithrombotic agents This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well a... | 12/31/2002 |
| 6498004 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity This invention provides a photographic element comprising at least one silver halide emulsion layer in which the silver halide is sensitized with a compound of the formula (a): Ɗ-(t)m -XY' (a) XY'-(t)m -Ɗ (b) Ɗ-(t)m -XY'-(... | 12/24/2002 |
| 6489383 | 2H-benzotriazole UV absorbers substituted with 1,1-diphenylalkyl groups and compositions stabilized therewith 2H-Benzotriazole UV absorbers substituted at the 3-position or at the 5-position of the phenyl ring by a 1,1-diphenylalkyl moiety, particularly a 1,1-diphenylethyl group, are particularly photostable in automotive coatings, and are of low color and exhibi... | 12/03/2002 |
| 6469004 | Benzoheterocycles and their uses as MEK inhibitors The invention provides compounds having formula (I), wherein W is OH, or derivatives of the carboxylic acid, and Q is a heterocyclo-condensed ortho-phenylene residue. These compounds are useful as MEK inhibitors, particularly in the treatment of prolifera... | 10/22/2002 |
| 6451887 | Benzotriazoles containing -cumyl groups substituted by heteroatoms and compositions stabilized therewith 2H-Benzotriazole UV absorbers substituted at the 3-position and/or the 5-position of the phenyl ring by -cumyl moiety which is substituted by a heteroatom are particularly photostable in automotive coatings, and are of low color and exhibit low vol... | 09/17/2002 |
| 6452018 | 2-(2'-hydroxyphenyl) benzotriazoles containing a 2,4-imidazolidinedione group and process for their preparation 2-(2'-hydroxyphenyl)benzotriazoles having general formula (I). The above 2-(2'-hydroyzphenyl)benzotriazoles having general formula (I) are useful as heat, oxygen and light stabilizers for organic polymers. In particular they are useful as UV stabilizers f... | 09/17/2002 |
| 6407254 | 2-(2'-hydroxyphenyl)benzotriazoles used as U.V. stabilizers 2-(2'-hydroxyphenyl)benzotriazoles having general formula (I). The above 2-(2'-hydroxyphenyl)benzotriazoles are useful as light stabilizers for organic polymers. ##STR1##... | 06/18/2002 |
| 6392056 | 2H-benzotriazole UV absorders substituted with 1,1-diphenylalkyl groups and compositions stabilized therewith 2H-Benzotriazole UV absorbers substituted at the 3-position or at the 5-position of the phenyl ring by a 1,1-diphenylalkyl moiety, particularly a 1,1-diphenylethyl group, are particularly photostable in automotive coatings, and are of low color and exhibi... | 05/21/2002 |
| 6387992 | Substituted 5-heteroaryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, a process for preparation thereof and compositions stabilized therewith Compounds of formula I or II ##STR1## where R is a heteroaryl moiety, such as 3-pyridyl, or T is a heteroaryl moiety, such as thien-2,5-diyl, and E1 and E2 are independently hydrogen, alkyl, aralkyl and the like, are prepared by reac... | 05/14/2002 |
| 6376065 | Fluorochemical benzotriazoles The invention provides compounds having the formula: ##STR1## wherein Rf is Cn F2n+1 --(CH2)m --, wherein n is 1 to 22 and m is 0, or an integer from 1 to 3; X is --CO2 --, --SO3... | 04/23/2002 |
| 6372759 | Antithrombotic agents This application relates to a compound of formula (I), a pharmaceutically acceptable salt of the compound, or a prodrug thereof, as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its... | 04/16/2002 |
| 6344454 | Nonsteroidal gestagens This invention describes the new, nonsteroidal gestagens of general formula I ##STR1## in which A, B, Ar, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very ... | 02/05/2002 |
| 6337402 | Asymmetrical bisbenzotriazoles substituted by a perfluoroalkyl moiety and compositions stabilized therewith Asymmetrical bisbenzotriazoles of the formula I ##STR1## where G2 ' is perfluoroalkyl of 1 to 12 carbon atoms, preferably CF3, and where G2 does not contain said group are red-shifted and due to the asymmetry are particula... | 01/08/2002 |
