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| Number | Title | Issue Date |
| 7696355 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants Novel isothiazolecarboxamides of the formula in which R is as defined in the description, a plurality of processes for preparing the novel compounds and their use for protecting plants against attack by ... | 04/13/2010 |
| 7595404 | Thiazolyl-substituted carbocyclic 1,3-diones as pesticidal agents The present invention relates to novel hetaryl-substituted carbocyclic 1,3-diones of the Formula (I) in which A, B, Q1, Q2, Q3, Q4, G, m and Het are as defined in the de... | 09/29/2009 |
| 7396846 | Growth hormone secretagogues This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in thes... | 07/08/2008 |
| 7384929 | N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are N-aryl or heteroaryl azaspiroalkene/alkane compounds, prodrugs or metabolites of these compounds, or pharmaceutically acceptab... | 06/10/2008 |
| 7271184 | Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides Novel pesticides of formula (I) wherein the substituents, R, R1, R2, R2′, T, U, X and Y are as defined in claim 1, are described. Also described are compositions suitable... | 09/18/2007 |
| 7229988 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses The present invention provides novel dialkylhydroxybenzoic acid derivatives containing metal chelating groups and the use of the novel compounds as therapeutics for treating and/or preventing various medical dysfunctions and diseases arising from reactive oxygen spe... | 06/12/2007 |
| 7205323 | Dipeptidyl peptidase IV inhibitors pharmaceutical compositions containing them, and process for their preparation The present invention relates to novel compounds useful as dipeptidyl peptidase IV (DPP-IV) inhibitors of the formula: wherein X, Y, a, R1, and R2 are as defined herein. ... | 04/17/2007 |
| RE39575 | Substituted thioacetamides The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases. ... | 04/17/2007 |
| 7183303 | Gamma-secretase inhibitors Compounds of formula I: inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease. ... | 02/27/2007 |
| 7169933 | N-sulfonylaminocarbonyl containing compounds Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The s... | 01/30/2007 |
| 7157481 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants Novel isothiazolecarboxamides of the formula in which R is as defined in the description, a plurality of processes for preparing the novel compounds and their use for protecting plants a... | 01/02/2007 |
| 7148240 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives of general formula: These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes of the cardiovascular... | 12/12/2006 |
| 7125863 | Inhibitors of dipeptidyl peptidase IV Compounds according to formula (1), wherein R1 is H or CN, X1 is S, O, SO2 or CH2, X2 is CO, CH2 or a covalent bond, Het is a nitrogen-containing heterocycle and n is 1–5 are new. The compounds of t... | 10/24/2006 |
| 7119112 | Sulfonamides as potassium channel blockers Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides sulfonamides, and compositions and met... | 10/10/2006 |
| 7105556 | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method Compounds are provided which have the structure wherein Q is C or N, X1 is C or N, and R1, R2, R2a, R2b, R2c, R3, Y, A, m, n, X2 | 09/12/2006 |
| 7067538 | MCP-1 receptor antagonists and methods of use thereof The present invention relates to sulfones that are useful in the treatment of chemokine-mediated disorders. In certain embodiments, the present invention concerns the compounds that are MCP-1 receptor antagonists. ... | 06/27/2006 |
| RE39140 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/20/2006 |
| RE39130 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/13/2006 |
| RE39127 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/13/2006 |
| RE39129 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/13/2006 |
| RE39131 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atoms or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted b... | 06/13/2006 |
| 7041670 | Florfenicol-type antibiotics The present invention relates to novel florfenicol compounds having the chemical structure: wherein the compounds are useful for the treatment and/or prevention of bacterial infections in a broad range of patients such... | 05/09/2006 |
| 7030239 | Compounds to treat Alzheimer's disease The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer's disease and other similar diseases. ... | 04/18/2006 |
| 6989451 | Heterocyclic compounds and uses thereof Substituted isothiazole compounds and compositions are provided, wherein particularly preferred compositions and methods are directed towards inhibition of various protein kinases (especially MEK and/or ERK). Consequently, particularly preferred methods include trea... | 01/24/2006 |
| 6987112 | Organic compound having cyano group and insecticides/miticides The present invention is directed to compounds represented by Formula (1); wherein A, R, X, Y and n are as defined in the description, the salts thereof, and insecticide/acaricide compositions characterized by comprisi... | 01/17/2006 |
| 6982336 | 1,2-dioxetane derivatives, luminescent reagents, luminescence methods and measuring methods A 1,2-dioxetane derivative of the formula (I): wherein R1–R3 and Ar are defined in the claims is provided. ... | 01/03/2006 |
| 6969749 | Azlactone initiators for atom transfer radical polymerization Initiators for atom transfer radical polymerizations are described. The initiators have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 11/29/2005 |
| 6967213 | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same The present invention relates to an isothiazole derivative of the following formula 1 or nontoxic salt thereof: wherein, R1 is hydrogen, alkoxy group or halogen group; R2 ... | 11/22/2005 |
| 6964975 | Isoxazole and thiazole compounds and use thereof as medicine The present invention relates to novel isoxazole and thiazole compounds having an excellent lysophosphatidic acid (LPA) receptor antagonistic activity represented by general formula [1] or salts thereof: wherein R1 and... | 11/15/2005 |
| 6951945 | Heteroaromatic glucokinase activators 2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 3-position being a substituted phenyl group and at the 2-position being a methyl cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secretion in the ... | 10/04/2005 |
| 6949536 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents This invention provides a compound of the formula: or its pharmaceutically acceptable salt thereof, wherein A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated ... | 09/27/2005 |
| 6936630 | Substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents Antiatherosclerotic agents are provided which are represented by Formulas I or II: wherein R is wherein R9, R10, R11 | 08/30/2005 |
| 6927216 | Cyclic sulfonyl compounds as inhibitors of metalloproteases The present application describes novel cyclic sulfonyl derivatives of formula I: or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms select... | 08/09/2005 |
| 6894041 | Oxazolyl-acid amide derivatives useful as inhibitors of PDE4 isozymes This application is directed to compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructuive pulmonary disease, of the formula: | 05/17/2005 |
| 6894133 | Azlactone initiators for atom transfer radical polymerization Initiators for atom transfer radical polymerizations are described. The initiators have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 05/17/2005 |
| 6894173 | Intermediates useful for synthesis of heteroaryl-substituted urea compounds, and processes of making same Disclosed are novel processes and novel intermediate compounds for preparing aryl-and heteroaryl-substituted urea compounds of the formula(I) wherein Ar1, Ar2, L, Q and X are described herein. The product compounds are useful in pharmaceutic co... | 05/17/2005 |
| 6884821 | Carboxylic acid derivatives and drugs containing the same Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R1 is hydro... | 04/26/2005 |
| 6875783 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants Novel isothiazolecarboxamides of the formula in which R is as defined in the description, a plurality of processes for preparing the novel compounds and their us for ... | 04/05/2005 |
| 6861561 | Substituted aromatic policyclic tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aromatic polycyclic tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and o... | 03/01/2005 |
| 6833370 | Heterocycle substituted aminoazacycles useful as central nervous system agents Heterocyclic substituted aminoazacyclic compounds of formula I Z—R3 I, wherein Z is a defined aminoazacycle and R3 is a defined heterocycle moiety, pharmaceutical compositions of these compounds, and use of said comp... | 12/21/2004 |
