"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
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| Number | Title | Issue Date |
| 7230020 | 11β-hydroxysteroid dehydrogenase inhibitors A compound having Formula I R1—Z—R2Formula I wherein R1 is an optionally substituted phenyl ring; R2 is or comprises an optionally substituted aromatic ring; and Z is —X—Y—L— or —Y—X—L... | 06/12/2007 |
| 6995262 | Use of acylsulfonamido-substituted polymethine dyes as fluorescene dyes and/or markers The invention relates to a novel polymethine dyes containing at least one acylsulfonamido group of the formula (I) in which n, Y, A and R have the meaning given in the claims, and at least one compound of the formulae ... | 02/07/2006 |
| 6939967 | Non-proteinogenic L-amino acids Process for production of non-proteinogenic L-amino acids by direct fermentation of a microorganism strain known per se having a deregulated cysteine metabolism in a manner known per se, which comprises adding, during the fermentation, a nucleophilic compound to the... | 09/06/2005 |
| 6777418 | Retinoid compounds (I) The current invention provide novel retinoid compounds and methods for their synthesis, methods of treating or preventing emphysema, cancer and dermatological disorders and pharmaceutical compositions suitable for the treatment or prevention of emphysema, cancer and... | 08/17/2004 |
| 6696456 | Beta disubstituted metalloprotease inhibitors Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the compounds have a structure according to the following Formula (I): #... | 02/24/2004 |
| 6586463 | C16 unsaturated FP-selective prostaglandins analogs Compounds having the general structure: ##STR1## which are useful for the treatment of a variety of diseases and conditions, such as bone disorders.... | 07/01/2003 |
| 6362138 | Heterocyclic thioethers as additives for lubricants This invention relates to compounds which are suitable as ash-free antiwear additives and antioxidants, to lubricant compositions comprising said compounds as well as to their use. ##STR1## are particularly preferred. In the preferred compounds I', R... | 03/26/2002 |
| 6319925 | O-benzyl oxime ether derivatives and their use in crop protection compositions ##STR1## Oxime ethers of formula (I) in which a) X is an N atom and Y is an oxygen atom or NH, or b) X is CH and Y is an oxygen atom, in which furthermore R1 is C1 -C4 alkyl; R2 is hydrogen, C1 -C4 | 11/20/2001 |
| 6313289 | Purification process Crystalline 2-(amninothiazol-4-yl)-2-(tert.butoxycarbonylmethoxyimino)acetic acid-S-mercapto-benzo-thiazolylester in form of an N,N-dimethylacetamide solvate; a crystalline salt of a 7-[2-(aminothiazol-4-yl)-2-(carboxymethoxyimino)acetamido]-3-vinyl-... | 11/06/2001 |
| 6255480 | Aminothiazole derivatives useful in the preparation of ଲ-lactam antibiotics Aminothiazole derivatives having the carboxyl activated by means of thioesters, said derivatives being condensable with ଲ-lactam nuclei to yield ଲ-lactam antibiotics... | 07/03/2001 |
| 6204380 | Production pyridazine herbicides Carboxylic acid ester derivatives of formula (1): ##STR1## wherein R is C1 -C6 alkyl, R2 and R3 are independently hydrogen or C1 -C3 alkyl, and Q is optionally substituted phenyl, can be ea... | 03/20/2001 |
| 6150307 | Heterocyclic thioethers as additives for lubricants This invention relates to compounds which are suitable as ash-free antiwear additives and antioxidants, to lubricant compositions comprising said compounds as well as to their use. Compounds of formulae ##STR1## are particularly preferred. In the pre... | 11/21/2000 |
| 6100406 | Benzothiazolylthio or thiadiazolylthio substituted phenols as multifunctional additives for lubricants Suitable lubricant additives are the compounds of formulae wherein the substituents and groups have the following preferred meanings: R1 =H; R2 =methyl or tert-butyl; R3 =tert-butyl; s=0, 1 or 2; R4 =--A--[(C6 ... | 08/08/2000 |
| 6020339 | Aryl furan derivatives as PDE IV inhibitors The invention encompasses the novel compound of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). ##STR1## ... | 02/01/2000 |
| 5980779 | Liquid crystalline compound and use thereof A process for producing a liquid crystalline compound represented by the following general formula (A): ##STR1##... | 11/09/1999 |
| 5942535 | a!-Annelated pyrrole derivatives and pharmaceutical use thereof The present invention relates to heterocyclic compounds of the formula ##STR1## in which R1 -R7, B, a and X have the meanings recited in the specification. These compounds are usable in the treatment of diseases of the rheumatoi... | 08/24/1999 |
| 5777162 | Intermediates for the preparation of fungicides Described herein are compounds of Formula (XX) and Formula (XXIV), shown below, and processes of making same. ##STR1## wherein p is 0 ##STR2## wherein p is 1, and Y is chlorine or bromine.... | 07/07/1998 |
| 5700819 | 2-substituted benzothiazole derivatives and prophylactic and therapeutic agents for the treatment of diabetic complications Unique benzothiazole derivatives which exert superior aldose redactase inhibiting actions are unexpectedly and advantageously useful in the prophylactic and therapeutic treatment of diabetic complications. A benzothiazole derivative compound of the formul... | 12/23/1997 |
| 5674811 | Cyanoketone derivative and herbicide containing it as an active component A cyanoketone derivatives of the following formula (1) ##STR1## which are characterized by excellent herbicidal activity and effectiveness against a variety of broad leafed weeds, including barnyard grass, green foxtail, velvet leaf, livid amaranth a... | 10/07/1997 |
| 5648370 | 7-(2-aminoethyl) benzothiazolones There are disclosed compounds of formula I, Ar--CH2 CH2 --NH--CR1 R2 --X--Y I in which Ar represents a group, ##STR1## X represents a C1-12 alkylene chain optionally interrupted or terminated b... | 07/15/1997 |
| 5618775 | Mixtures of optically active cyclohexenone oxime ethers, their preparation, intermediates for this purpose and their use as herbicides Mixtures of optically active cyclohexenone oxime ethers having R- and S-configuration in the oxime ether moiety of the formula I ##STR1## (R1 =C1 -C6 -alkyl; ##STR2## X=C1-C.sub.4 -alkyl, C1... | 04/08/1997 |
| 5597819 | Phenothiazine cytokine inhibitors New benzothiazine derivatives corresponding to the general formula I: ##STR1## in which: X represents halogen, n represents 0, 1, or 2, B represents the following formula: ##STR2## in which: R1 & R2 together with the carbons to ... | 01/28/1997 |
| 5563168 | O-Benzyloxime ethers and crop protection agents containing these compounds O-Benzyloxime ethers of the formula I ##STR1## where 5 X is substituted or unsubstituted CH2, NOalkyl Y is O, S, NR5 R1, R2, R5 are H, alkyl Z1, Z2 are H, halogen, methyl, methoxy, cy... | 10/08/1996 |
| 5556990 | Polyarylcarbamoylaza- and -carbamoylalkanedioic acids This invention relates to a class of novel dicarboxy amide derivatives of lipophilic amines which exhibit squalene synthase inhibition properties. More specifically the compounds are bis-aryl and/or heteroaryl alkyl or cycloalkylamino dicarboxy amides. Co... | 09/17/1996 |
| 5550143 | Heterocyclic compounds A compound of formula (I): ##STR1## in which X, n, B and Y are as defined in the description. useful as cytokine inhibitors.... | 08/27/1996 |
| 5550229 | Alkylation process for preparing azetidinone compound and starting compound therefor Novel process for preparing azetidinone compound of the formula [III]: ##STR1## wherein R1 is H or lower alkyl, R2 and R3 combine together with the adjacent nitrogen to form heterocyclic group, and R4 is pr... | 08/27/1996 |
| 5529998 | Benzoxazolyl- and benzothiazolyloxazolidinones The invention relates to benzoxazolyl- and benzothiazolyloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.... | 06/25/1996 |
| 5521145 | Iminothiazoline derivatives and herbicides containing them as active ingredients There is disclosed an iminothiazoline derivative of the general formula: ##STR1## wherein R1 is (halo)alkyl, (halo)alkenyl, (halo)alkynyl or the like; R2 is (halo)alkyl, optionally substituted aryl, formyl, cyano or the like; R | 05/28/1996 |
| 5519136 | Radiation sensitive compounds A radiation-sensitive compound has the general formula ##STR1## wherein A represents the ring members required to complete a 5- or 6-membered heterocyclic ring which may optionally be fused to an optionally substituted aromatic nucleus, B represents ... | 05/21/1996 |
| 5492925 | Thienyl-and furylpyrrole insecticidal and acaricidal agents There are provided thienyl- and furylpyrrole compounds of formula I ##STR1## and their use for the control of insects and acarina. Further provided are compositions and methods comprising those compounds for the protection of plants from attack by in... | 02/20/1996 |
| 5470863 | Oximic derivatives with a fungicide activity A description follows of oximic derivatives with a fungicide activity, for agricultural use, having the formula (I): ##STR1## wherein: A, B, D, are N, or .dbd.C--G; G is H, halogen, NO2, CN, --COOR4, C1 -C6 (hal... | 11/28/1995 |
| 5451594 | Heterocyclic compounds The invention provides compounds of formula (I) having nematicidal, insecticidal, acaricidal and fungicidal properties, compositions comprising them and processes and intermediates for their preparation: ##STR1## wherein: X is oxygen or sulphur; n is... | 09/19/1995 |
| 5380735 | Benzothiazole derivatives and methods of use The present invention relates to a novel benzothiazole derivative of the following general formula (I) or its (E) , (Z)isomer, and processes for preparation thereof, ##STR1## in which R1, R2 and R3 independently of on... | 01/10/1995 |
| 5374644 | Fungicides Compounds of formula: ##STR1## and stereoisomers thereof, wherein X, Y and Z, which are the same or different, are hydrogen, halogen, hydroxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted aryl, optionally ... | 12/20/1994 |
| 5347008 | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents Compounds of the formula ##STR1## in which X is --S--, --O-- or --NH--, R is H or a monovalent substituent, n is 0 or 1 and R1, R2, R3 and R4 are H, alkyl, alkyl which is substituted by OH, halogen, COOH or... | 09/13/1994 |
| 5338844 | 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient A 2-substituted-2-cyclopentenone compound represented by the following formula (I) and an anticancer agent and a bone formation accelerator comprising the same as an effective active ingredient: ##STR1##... | 08/16/1994 |
| 5300521 | Pyrazoles, fungicidal compositions and use The invention compounds of formula I ##STR1## wherein R is H, C1-4 alkyl; optionally substituted aryl or CF3 ; Y is C1-4 alkyl or optionally substituted aryl; A is nitrogen or CH; and Z is optionally substituted hydrocarbyl or ... | 04/05/1994 |
| 5258521 | Process of producing optically active propionic acid ester derivatives Processes for producing optically active ester derivatives are disclosed. According to the present invention an optically active aryloxyphenoxy propionate derivative is produced by reacting a chlorinated heterocyclic aromatic compound with (2R)-2-(4-hydro... | 11/02/1993 |
| 5258395 | Thiazole compounds as inhibitors of SRS-A Novel heterocyclic compounds shown by the general formula ##STR1## or the pharmaceutically acceptable salts thereof useful as medicament in particular as antagonist of slow reacting substance of anaphylaxis (SRS-A).... | 11/02/1993 |
| 5240919 | Benzthiazolinonyl-substituted alkylamides Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.... | 08/31/1993 |