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| Number | Title | Issue Date |
| 7994337 | Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors A compound of Formula (I) an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, wherein A is independently selected from: further wherein R1, R | 08/09/2011 |
| 7473784 | Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors A compound of Formula (I) an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, wherein A is as described herein. Also disclosed is a compound of Formula (II) ... | 01/06/2009 |
| 7390908 | Compounds effecting glucokinase The invention relates to the use of a compound of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, in the preparation of a medicament for the treatment or preventio... | 06/24/2008 |
| 7351481 | Imidazole ring-containing compound and organic electroluminescence display device The present invention is related to an imidazole ring-containing compound and an organic electroluminescence (EL) display device using the same. In particular, the imidazole ring-containing compound may be used alone or in combination with a dopant as a material for... | 04/01/2008 |
| 7348347 | Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds Substituted 4,5,6,7-tetrahydrobenzothiazol-2-ylamine compounds, a method for their production; pharmaceutical compositions comprising them, and methods of use for modulating biological functions and/or treating or inhibiting various medical conditions such as, e.g.,... | 03/25/2008 |
| 7329288 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof The present disclosure relates to a novel family of N-heteroaryl secondary para-phenylenediamines, to their preparation, to their use for dyeing the hair and to a dye composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprisi... | 02/12/2008 |
| 7304086 | Inhibitors of glutaminyl cyclase The present invention relates to novel inhibitors of glutaminyl cyclase and combinations thereof for the treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophre... | 12/04/2007 |
| 7304058 | Carbamic acid esters of benzothiazoles The present invention relates to a compound of formula I wherein R, X and n are defined hereinabove, and to a pharmaceutically acceptable salt thereof. The compound may be used for the treatment of diseases relat... | 12/04/2007 |
| 7282608 | Inhibitors of histone deacetylase The invention provides compoods and methods for treating cell proliferative-diseases. The invention provides new inhibitors of histone deacetylase enzymatic activity, compositions of the compounds comprising the inhibitors and a pharmaceutically acceptable carrier, ... | 10/16/2007 |
| 7244278 | Agent and method for oxidative coloring of keratin fibers The object of the present invention is a ready-to-use agent for coloring keratin fibers containing (i) at least one heterocyclic hydrazone derivative of formula (I), (ii) at least one aromatic enamine of formula (IIa) or an acid addition compound thereof (IIb) and (... | 07/17/2007 |
| 7153815 | Insecticide containing hydrazone derivative as the active ingredient and novel hydrazone derivative A insecticide characterized by containing as active ingredient a hydrazone derivative of formula (I) wherein A and Q are an aryl or a heterocyclic group, W is oxygen atom, an aminylene, an alkylene group, an oxya... | 12/26/2006 |
| 7141594 | Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particula... | 11/28/2006 |
| 7141595 | Amino benzothiazole compounds with NOS inhibitory activity The present invention provides novel amino benzothiazole compounds, compositions comprising these compounds and methods of using these compounds as neuroprotectants. In particular, the compounds described in the present invention are useful for treating stroke and n... | 11/28/2006 |
| 7125893 | 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations This invention describes the new 6-alkenyl- and 6-alkinyl-epothilone derivatives of general formula I in which R1a, R1b, R2a, R3a, R3b, R4, R... | 10/24/2006 |
| 7091227 | Benzothiazole derivatives The present invention is directed to a compound of formula (I), racemic-diastereomeric mixtures thereof, optical isomers thereof, prodrugs thereof, isotopes thereof or pharmaceutically-acceptable salts of said co... | 08/15/2006 |
| 7091228 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases. ... | 08/15/2006 |
| 7041691 | Compounds for the modulation of PPARγ activity Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity. ... | 05/09/2006 |
| 7030135 | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 The present invention relates to using a compound having the formula (I) wherein T is I) thienyl, which optionally is substituted with halogen, or II) phenyl optionally substituted with halogen and/or C1-6-alkyl; E is a bond, —CH2— or —CO... | 04/18/2006 |
| 7022823 | Diazonium salt, its synthesizing method and recording material The present invention relates to a diazonium salt represented by the following general formula (1) and a synthesizing method thereof, as well as a recording material using the diazonium salt. In general formula (1), R1 represents a hydrogen atom, a... | 04/04/2006 |
| 6825355 | Benzothiazole protein trosine kinase inhibitors Novel benzothiazoles and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic disorders. ... | 11/30/2004 |
| 6825223 | Anilide compounds and pharmaceutical compositions comprising them The invention provides novel anilide compounds and pharmaceutical compositions comprising them. The invention relates to compounds of a formula: wherein Ar is an optionally-substituted aryl group; ... | 11/30/2004 |
| 6770761 | Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles A new process to obtain pramipexole and related products is described. The process involves the reaction of new compounds of formula (6), wherein R is hydrogen or acyl group, R3 and R4 are either the same and each of them represents an alkoxy g... | 08/03/2004 |
| 6673822 | Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, mor... | 01/06/2004 |
| 6656939 | Pyrazole compounds useful as protein kinase inhibitors This invention describes novel pyrazole compounds of formula III: ##STR1## wherein Z1, Z2, and Z3 are as described in the specification; Q is --S--, --O--, --N(R4)--, or --CH(R6)--; R1 is T... | 12/02/2003 |
| 6518291 | Inhibitors of IMPDH enzyme The present invention relates to a novel class of compounds which are IMPDH inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly... | 02/11/2003 |
| 6495693 | N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting ଲ-amyloid peptide release and/or its synthesis by use of such compounds Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid... | 12/17/2002 |
| 6441184 | Fused heteroaromatic glucokinase activators Glucokinase activating amides are useful for increasing insulin secretion in the treatment of type II diabetes.... | 08/27/2002 |
| 6441012 | Chemical compounds ##STR1## Compound of formula (I) wherein: A is a bicyclic heteroaryl, optionally substituted with one or more substituents; B is linker group connecting group A to group D and comprising a 3 or 4 atom linker where each atom is independently selected from ... | 08/27/2002 |
| 6433188 | Fused heteroaromatic glucokinase activators Glucokinase activating amides as herein disclosed are useful for increasing insulin secretion in the treatment of type II diabetes.... | 08/13/2002 |
| 6432962 | Benzophenones as inhibitors of IL-1ଲ and TNF- Heteroaryl aminobenzophenones of general formula I inhibit interleukin-1ଲ and TNF- and may therefore be useful in the therapy of inflammatory diseases and conditions.... | 08/13/2002 |
| 6399628 | N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting alpha- amyloid peptide release and/or its synthesis by use of such compounds Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid... | 06/04/2002 |
| 6362208 | Anilide compounds and drugs containing the same The invention relates to a novel anilide compound and a pharmaceutical composition comprising the same. The invention relates to a compound represented by the following general formula: ##STR1## represents a divalent residue of benzene with a substituent(... | 03/26/2002 |
| 6353006 | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and t... | 03/05/2002 |
| 6303643 | Substituted indoles and uses thereof This invention is directed to indole and benzothiazole compounds which are selective for cloned human alpha 2 receptors. This invention is also related to uses of these compounds for any indication where use of an alpha 2 agonist may be appropriate. Speci... | 10/16/2001 |
| 6268313 | Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production The dihalopropene compounds of the general formula [I] have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks.... | 07/31/2001 |
| 6232470 | Substituted pyrazol-3-ylbenzazoles, their use as herbicides or desiccants/defoliants, and their preparation Substituted Pyrazol-3-ylbenzazoles I ##STR1## salts thereof, and their use as herbicides or for the desiccation/defoliation of plants.... | 05/15/2001 |
| 6204278 | Anilide compounds, including use thereof in ACAT inhibitition The invention provides novel anilide compounds and pharmaceutical compositions comprising them. The invention relates to compounds of a formula: ##STR1## where Ar is an optionally-substituted aryl group; R4 and R5 are the same or differen... | 03/20/2001 |
| 6201126 | Isoindolenineamide dyestuffs Compounds of the formula (I) ##STR1## in which A represents N or a cyanomethylene radical, B represents S, O or NH and R1, R2, R3 and x have the meaning given in the description, are highly suitable for dyeing and printing high... | 03/13/2001 |
| 6124242 | Herbicidal compositions and processes based on ferrodoxin:NADP reductase inhibitors There are described ferredoxin:NADP reductase inhibitors, an assay system for the search for such inhibitors, and their use as herbicides.... | 09/26/2000 |
| 6084101 | Naphtol derivative and process for producing the same The present invention relates to a novel 2-hydroxy-naphthalene-3,6-dicarboxylic acid derivative. The compound is useful as a raw material for dyes, pigments, photosensitive materials and the like.... | 07/04/2000 |
