...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 7291741 | Process of production of n-alkyl-2-benzthiazolysulfeneimides, device for their production and method of their purification The solution concerns a process of production of N-alkyl-2-benzthiazolylsulfeneimides by means of a reaction of 2-benzthiazolylsulfenyl chloride with an excess of a corresponding alkylamine in an anhydrous reaction medium. Removement of water and moisture from the r... | 11/06/2007 |
| 7265088 | Method and compositions for altering mucus secretion Methods and compounds for increasing or decreasing mucus secretion in subjects, and particularly mucus secretion in the airways, are described. Methods of screening compounds for the ability to increase or decrease mucus secretion are also described. ... | 09/04/2007 |
| 7052702 | Conjugates of galactose-binding lectins and clostridial neurotoxins as analgesics A class of novel agents that are able to modify nociceptive afferent function is provided. The agents may inhibit the release of neurotransmitters from discrete populations of neurones and thereby reduce or preferably prevent the transmission of afferent pain signal... | 05/30/2006 |
| 6908726 | Thermally imageable elements imageable at several wavelengths Infrared absorbing compounds that absorb at 800 nm±50 nm and at 1050 nm±50 nm, the two different regions of the infrared spectrum typically used for imaging, are disclosed. Thermally imageable elements that comprise these infrared absorbing compounds can be imaged... | 06/21/2005 |
| 6869913 | Pyridazin-3-one derivatives, their use and intermediates for their production Novel pyridazin-3-one derivatives of formula [1] are provided, which are useful as active ingredients of herbicides, wherein R1 is haloalkyl; R2 and R3 are hydrogen, alkyl, haloalkyl, o... | 03/22/2005 |
| 6281238 | 4-aryl-1-oxa-9-thia-cylopenta[B]fluorenes This invention provides compounds of Formula I having the structure ##STR1## wherein B and D are each, independently, hydrogen, halogen, --CN, alkyl of 1-6 carbon atoms, aryl, or aralkyl of 6-12 carbon atoms; R1 is hydrogen, alkyl of 1-6 carbon atom... | 08/28/2001 |
| 6225331 | Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists This invention involves compounds having the following structure: ##STR1## as described in the claims; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, as well as pharmac... | 05/01/2001 |
| 6184385 | Process for the manufacture of a sulfenimide A process for the manufacture of a sulfenimide by reacting sulfenamide in slurry with a water immiscible organic solvent with an acid to yield a solvent slurry comprising sulfenimide product. The product is recovered from the solvent slurry by a method co... | 02/06/2001 |
| 6180795 | Process for making N-alkyl bis(thiazolyl)sulfenimides There is disclosed a process for the preparation of sulfenimides comprising: mixing, in a hydrocarbon solvent, a sulfenamide of the formula ##STR1## with an aldehyde of the formula R4 CHO where X is a sulfur atom, a --C.dbd.N-- group, or a --C.dbd.C... | 01/30/2001 |
| 6139782 | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes Novel heterocyclic compounds which generate chemiluminescence on reaction with a phosphatase enzyme are provided as well as a process for their preparation and intermediates useful therein. The compounds comprise a nitrogen, oxygen or sulfur-containing he... | 10/31/2000 |
| 6045991 | Compositions and methods for generating red chemiluminescence Compounds which generate red chemiluminescence on reaction with a phosphatase enzyme are provided as well as intermediates useful for their preparation. The chemiluminescent compounds comprise a luciferin ring system and an exocyclic enol phosphate group ... | 04/04/2000 |
| 5942547 | 2-Deoxystreptamine derivatives, pharmaceutical compositions thereof and therapeutic methods using same This invention provides a compound having the formula: ##STR1## wherein R1 and R3 independently are hydrogen, --CHO, --COCH3, --COR7, --A--Ar--(Q)z, etc.; wherein D is a C1-6 linear, C... | 08/24/1999 |
| 5716756 | Sulfonic acid esters, radiation-sensitive mixtures prepared therewith and their use Sulfonic acid esters are used as (a) compounds for forming a strong acid on irradiation in radiation-sensitive, positive or negative working mixtures also comprising (b) either a compound with at least one acid-decomposable C--O--C or C--O--Si bond (for p... | 02/10/1998 |
| 5424442 | Water-soluble methine compounds useful in photographic silver halide emulsion containing the same A water-soluble methine compound represented by the following general formula (I): ##STR1## wherein Z1 and Z2, which may be the same or different, each represents a non-metallic atomic group required for forming a 5-membered ... | 06/13/1995 |
| 5371222 | Alkoxyiminoacetamide derivatives and their use as fungicides A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R1 and R2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R3 is lower alkyl or cyclo(lower)alkyl; R4... | 12/06/1994 |
| 5371223 | Alkoxyiminoacetamide derivatives and their use as fungicides A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R1 and R2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R3 is lower alkyl or cyclo(lower)alkyl; R4... | 12/06/1994 |
| 5349001 | Cyclic imide thione activated polyalkylene oxides Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.... | 09/20/1994 |
| 5286870 | Process for the production of bis-benzthiazolyl alkyl sulfenimides Bis-benzthiazolyl alkyl sulfenimides are produced by a process in which alkyl amines are reacted with optionally substituted 2-mercaptobenzthiazoles in the presence of oxygen or oxygen-containing gases and copper and/or copper compounds and in the presenc... | 02/15/1994 |
| 5204481 | Process for preparing benzothiazole sulfenimides using an aliphatic hydrocarbon solvent An improved process for producing N-alkyl or N-cycloalkyl-2-benzothiazole sulfenimides uses aliphatic hydrocarbons as a reaction medium in converting N-alkyl or N-cycloalkyl-2-benzothiazole sulfenamides to the corresponding sulfenimides by reaction with a... | 04/20/1993 |
| 5185342 | Alkoxyiminoacetamide derivatives and their use as fungicides A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R1 and R2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R3 is lower alkyl or cyclo(lower)alkyl; R4... | 02/09/1993 |
| 5169950 | Processes for preparing phenolic benzothiazole derivatives Compounds of the formula I ##STR1## wherein R, R1, R2, R3, and R5 have the meaning given in claim 1 are formed by thermal rearrangement of the isomers of formula V ##STR2## especially in the presence o... | 12/08/1992 |
| 5110941 | Methods of producing 1H-pyraolo(5,1-c)-1,2,4-triazoles and pyrazole derivatives A method of producing 1H-pyrazolo[5,1-c]-1,2,4-triazoles represented by general formula (II): ##STR1## (wherein R1, R2 and R3 each represents a hydrogen atom or a substituent group) which comprises making a compound r... | 05/05/1992 |
| 5103007 | Lipids Lipid derivatives represented by the formula: ##STR1## wherein R1 stands for an optionally substituted higher alkyl group, R2 stands for an optionally substituted lower alkyl group or an optionally substituted nitrogen-containin... | 04/07/1992 |
| 5081245 | Carboxylic acid derivatives A compound represented by the formula: ##STR1## wherein R represents a hydrogen atom or a lower alkyl group; R1 represents a higher alkyl group which may be substituted; R2 represents a hydrogen atom or a lower alkyl group, a lower alkano... | 01/14/1992 |
| 5073279 | Sulfur coupled hydrocarbyl derived mercaptobenzothiazole adducts as multifunctional antiwear additives and compositions containing same Sulfur-coupled hydrocarbyl derived mercaptobenzothiazole adducts have been found to be effective multifunctional antiwear additives for fuels and lubricants.... | 12/17/1991 |
| 5055477 | Pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection A pyrazolyl acrylic acid derivative having plant fungicidal activity of formula (I): ##STR1## wherein: R1 and R2 are independently hydrogen or C1 -C5 alkyl; A is a group of the formula: ##STR2## w... | 10/08/1991 |
| 5055582 | Process for preparing thromboxane A2 antagonists This invention relates to a process for preparing useful thromboxane A2 inhibiting (b1;)7-[3-[1-[[(phenylamino)thioxomethyl]hydrazono]ethyl]-1 ,4-bicyclo[2.2.1]hept-2ଲ-yl]-heptenoic acids and useful derivatives ... | 10/08/1991 |
| 5032590 | Substituted hydroxylamines Substituted hydroxylamines of the formula ##STR1## in which R1 stands for an aromatic or heterocyclic radical, are especially useful in the treatment of hyperlipoproteinaemia, lipoproteinaemia and atherosclerosis.... | 07/16/1991 |
| 4914206 | Lankacidin derivatives and production thereof The present invention provides lankacidin derivatives of the formula ##STR1## and procedures for the production thereof. The lankacidin derivatives [1] show excellent antimicrobial activities and thus can be used for prophylaxis and treatment of infe... | 04/03/1990 |
| 4873346 | Substituted benzothiazoles, benzimidazoles, and benzoxazoles The present invention provides certain novel substituted benzothiazoles, benzimidazoles and benzoxazoles which are useful as inhibitors of leukotriene biosynthesis and/or as inhibitors of the action of lipoxygenase and/or as inhibitors of mucus secretion ... | 10/10/1989 |
| 4746351 | Herbicidally active substituted phenoxy benzoxazole (or benzothiazole) This invention relates to herbicidally active substituted benzoxazole (or benzothiazole) compounds and to the use of such compounds to control the growth of noxious plants, i.e., weeds.... | 05/24/1988 |
| 4724201 | Photoresponsive material A photoresponsive material containing a dye compound having a cyclodextrin or its derivative as a substituent. The photoresponsive material exhibits increased light absorptivity by increasing the amount of spectral sensitizer, the dye compound. The photor... | 02/09/1988 |
| 4701512 | Isocyanate adducts with benzoxazolones or benzoxazinediones and use thereof as latent chain extenders or cross-linkers for epoxides The adducts of isocyanates wtih benzoxazolones or benzoxazinediones are novel compounds which may be employed as blocked isocyanates and are particularly useful as latent, epoxide curing agents. At typical epoxide curing temperatures, the isocyanate is ox... | 10/20/1987 |
| 4591647 | Process for the production of 2,2'-dibenzothiazolyl disulphide 2,2'-dibenzothiazolyl disulphide produced from an alkali metal salt of 2-mercaptobenzothiazole by oxidation using chlorine is obtained substantially free from acid by-products if oxidation is carried out under such conditions that the reaction mixture sti... | 05/27/1986 |
| 4585575 | 2-substituted-6-(5-substituted-2-pyrimidinyl)naphthalenes Novel liquid crystal compounds having superior properties and liquid crystal compositions containing the same are provided, which compounds are expressed by the general formula ##STR1## wherein R1 represents an alkyl group or an alkoxy gro... | 04/29/1986 |
| 4524128 | Spectrally sensitized silver halide photothermographic material Photographic silver halide is spectrally sensitized by means of at least one bleachable spectral sensitizing dye comprising a cyanine dye nucleus and a particular N-methylene substituent. The spectrally sensitized photographic silver halide is useful in a... | 06/18/1985 |
| 4413999 | Amidoxime derivatives, processes for the preparation The invention provides amidoxime derivatives of the general formula ##STR1## wherein R1 is an alkyl group of 1 to 8 carbon atoms, phenyl, a heterocyclic ring structure of 5 to 8 atoms containing one or more nitrogen or oxygen atoms or comb... | 11/08/1983 |
| 4374142 | Bisdithiocarbamate esters of di-lower alkyl formals Bisdithiocarbamate esters of di-lower alkyl formals and related compounds are disclosed. The final products are useful as rubber cure accelerators, biocides, antioxidants, corrosion inhibitors, and sulfur bearing oil additives.... | 02/15/1983 |
| 4371388 | 3-Substituted aminoalkyl-2-benzothiazolinones as plant growth regulants This disclosure relates to 3-substituted aminoalkyl-2-benzothiazolinones which are useful as plant growth regulants. More specifically, this disclosure relates to 3-substituted aminoalkyl-2-benzothiazolinones and compositions containing said compounds and... | 02/01/1983 |
| 4187097 | N-hydrazides of 2-benzothiazolinone as plant growth regulants N-hydrazides of 2-benzothiazolinone have been found to be effective in regulating the growth of leguminous plants.... | 02/05/1980 |