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| Number | Title | Issue Date |
| 7439242 | PPARγ modulators Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity. ... | 10/21/2008 |
| 7371746 | 1,2,4-Thiadiazole compounds and pests controlling composition containing the same The present invention relates to a 1,2,4-thiadiazole compound of the formula (I) represented by the formula (1): wherein R1? represents C3-C7 alkynyl and X represents C4-C7 straight alkylene optionally substituted with one to four of R2?, C4-C7 straight alkenylene o... | 05/13/2008 |
| 7368479 | Alpha-sulfonylamino-acetonitriles The invention relates to α-sulfonylamino-acetonitrile derivatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein Ar1, and Ar2 independently of each other stand for an optionally substitut... | 05/06/2008 |
| 7361675 | 1,2,4-thiadiazole compounds and use thereof 1,2,4-Thiadiazole compounds represented by the formula (1) have excellent control activities against harmful arthropods: wherein R1 represents C3-C7 alkynyl group optionally substituted one or more halogen atom(s... | 04/22/2008 |
| 7342039 | Substituted indole oximes The present invention relates to substituted indole oximes and methods of using them. ... | 03/11/2008 |
| 7342031 | Thiadiazole compound and use thereof The thiadiazole compound represented by the formula (A): wherein R1 represents a C1-C7 alkyl group, a C3-C7 alkenyl group, a C3-C7 alkynyl group and the like; R2 represents a C1-C4 alkyl group substituted with a ... | 03/11/2008 |
| 7301032 | 1,2,4-thiadiazole compounds and arthropod controlling composition containing the same The present invention relates to a novel 1,2,4-thiadiazole compound represented by the formula (1): wherein, R1 represents C3-C7 alkynyl that may be substituted with halogen at... | 11/27/2007 |
| 7273879 | Thiadiazole compounds and use thereof A thiadiazole compound of the formula (A): wherein R1 represents methyl, C3-C7 alkenyl, C2-C7 alkoxyalkyl, C2-C7 alkylthioalkyl, C4-C7 alkoxyalkoxyalkyl, C4-C7 alkylthioalkoxyalkyl, phenyl C1-C2 alk... | 09/25/2007 |
| 7253195 | Compounds for the treatment of neurodegenerative disorders The present invention relates to compounds of the Formula wherein R3, R5, R7, U, X, Y and Z are as defined. Compounds of the Formula I have activity inhibiting production of Aβ-p... | 08/07/2007 |
| 7015329 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 03/21/2006 |
| 6987112 | Organic compound having cyano group and insecticides/miticides The present invention is directed to compounds represented by Formula (1); wherein A, R, X, Y and n are as defined in the description, the salts thereof, and insecticide/acaricide compositions characterized by comprisi... | 01/17/2006 |
| 6872737 | Heterocyclic inhibitors of glycogen synthase kinase GSK-3 Compounds of general formula (I): where A, E, G, X, Y and the bond - - - take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is ... | 03/29/2005 |
| 6861106 | Dichroic dye, composition thereof, and liquid crystal composition and liquid crystal display element containing the same Dichroic dyes, dichroic dye compositions, and liquid crystal composition and liquid crystal display element containing the dichroic dyes. The dichroic dye has increased solubility and stability. ... | 03/01/2005 |
| 6632817 | Fluoromethoximino compounds The invention relates to novel fluoromethoximino compounds, to a process for their preparation and to their use as pesticides, and also to novel intermediates and to a plurality of processes for their preparation.... | 10/14/2003 |
| 6544931 | Substituted heteroaryloxyacetanilides and their use as herbicides The invention relates to novel substituted heteroaryloxyacetanilides of the general formula (I), ##STR1## in which n, R, X, and Z are to intermediates for their preparation and to their use as herbicides.... | 04/08/2003 |
| 6521650 | Amines as pharmaceutical agents Novel gamma aminobutyric acids of formula (I) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorder... | 02/18/2003 |
| 6518289 | 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders Novel amines of formulas (1), (1C), (1F), (1G) and (1H) or a pharmaceutical acceptable salt thereof wherein n is an integer of from 0 to 2; m is an integer of from 0 to 3; R is sulfonamide, amide, phosphonic acid, heterocycle, sulfonic acid, or hydroxamic... | 02/11/2003 |
| 6503934 | Substituted thiadiazolesulfonamides Compounds of the formula (I): ##STR1## are suitable for the preparation of pharmaceuticals for prophylaxis and treatment of all those diseases where an increased concentration of interleukin-1ଲ participates in their course, for example septic s... | 01/07/2003 |
| 6500944 | Sulfurizing reagent: 3-aryl-1,2,4-dithiazoline-5-ones The invention relates to the chemical synthesis of oligonucleotides and to chemical entities useful in such synthesis. More particularly, the invention relates to sulfurization of the internucleotide linkages of oligonucleotides. The invention provides a ... | 12/31/2002 |
| 6495551 | Substituted phenyloxazolidinones and their use as antibiotics The invention concerns compounds of formula (I), ##STR1## wherein, for example, R1 is of the formula --NHC(.dbd.O)Ra wherein Ra is (1-4C)alkyl; R2 and R3 are independently hydrogen or fluoro; R5... | 12/17/2002 |
| 6342245 | Compositions of lipid lowering agents The present invention is concerned with novel pharmaceutical compositions of lipid lowering agents which can be administered to a mammal suffering from hyperlipidemia, obesitas or atherosclerosis, whereby a single such dosage form can be administered once... | 01/29/2002 |
| 6323315 | Dolastatin peptides The present invention provides compounds of the formula ##STR1## where R1 -R5 are each, independently, a hydrogen atom or a normal or branched C1 -C6 -alkyl group; A is a methionyl, phenylalanyl or phenylglycyl ... | 11/27/2001 |
| 6306855 | Fluoromethoximino compounds The invention relates to novel fluoromethoximino compounds, to a process for their preparation and to their use as pesticides, and also to novel intermediates and to a plurality of processes for their preparation.... | 10/23/2001 |
| 6218412 | Substituted thiadiazolesulfonamides Compounds of the formula (I): ##STR1## are suitable for the preparation of pharmaceuticals for prophylaxis and treatment of all those diseases where an increased concentration of interleukin-1ଲ participates in their course, for example septic s... | 04/17/2001 |
| 6114537 | Process for scavenging thiols Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing a 1,2,4-thiadiazole ring structure carrying a substituent at position 3 of the thiadiazole ring, and being unsubstituted at position N-2. The... | 09/05/2000 |
| 6096895 | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful as fungicides ##STR1## In said formula, E is a ring system selected from certain 5- to 12-membered monocyclic and fused bicyclic aromatic het... | 08/01/2000 |
| 6031107 | Fluoromethoxyacrylic acid derivatives and their use as pest control agents The invention relates to new fluoromethoxyacrylic acid derivatives, a process for their preparation and their use as pesticides, as well as to new intermediates and a plurality of processes for their preparation. It has already been disclosed that certain fluo... | 02/29/2000 |
| 6022868 | Substituted azacyclic or azabicyclic compounds Disclosed are compounds of formula (I) selected from the following ##STR1## wherein Y is ##STR2## and wherein A, B, C, D, R, k, m, n, o, p, s, t and u are as defined in the specification. These compounds are useful in treating diseases in the ... | 02/08/2000 |
| 5981556 | 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors 1,3-diazolino and 1,3-diazolidino heterocycle derivatives useful as nitric oxide synthase inhibitors.... | 11/09/1999 |
| 5977149 | Dihydrotriazole compounds and their use for controlling fungal plant diseases Cyclic amides of Formula (I) which are useful as fungicides wherein: A is O; S; N; NR5 ;or CR14--, G is C or N; W is O or S; X is OR1, S(O)m R1 or halogen; R1, R2, and R5 a... | 11/02/1999 |
| 5977123 | Oximether and acrylic acid derivatives and their use as fungicides The invention relates to novel oximether and acrylic acid derivatives of the formula (I) ##STR1## in which Z, G, Ar, E, R1 and R2 have the meanings as given in the specification, to processes for their preparation and to their u... | 11/02/1999 |
| 5972978 | Modulators of molecules with phosphotyrosine recognition units The present invention relates to novel organic compounds, to methods for their preparation, to compositions containing them, to their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their... | 10/26/1999 |
| 5958958 | 1,2,4-oxa diazolino and 1,24-oxa diazolidion heterocycles as useful nitric oxide synthase inhibitors 1,2,4-oxa-diazolino and 1,2,4-oxa-diazolidino heterocycle derivatives useful as nitric oxide synthase inhibitors.... | 09/28/1999 |
| 5958957 | Modulators of molecules with phosphotyrosine recognition units The present invention relates to novel organic compounds, to methods for their preparation, to compositions containing them, to their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their... | 09/28/1999 |
| 5929075 | Apolipoprotein-B synthesis inhibitors The present invention provides novel compounds of formula ##STR1## the N-oxides, the stereochemically isomeric forms thereof, and the pharmaceutically acceptable acid addition salts thereof, wherein A and B taken together form a bivalent radical of f... | 07/27/1999 |
| 5852168 | Sulfurization of phosphorus-containing compounds The present invention provides a method for sulfurizing a phosphorus-containing compound, such as a trivalent phosphorus compound, using a disulfide-containing five-membered heterocycle.... | 12/22/1998 |
| 5849216 | Compounds for use in liquid-crystal mixtures Compounds of the formula (I) R1 --(A1)a (--M1)b --(--A2)c (--M2)d (--A3)e (--M3)f (--A4)g --H(I... | 12/15/1998 |
| 5827800 | Alkyl sulphinyl and alkyl sulphonyl-1,2,4-thiadiazolyloxy acetamides and their use as herbicides The invention relates to novel alkyl sulphinyl and alkyl sulphonyl-1,2,4-thiadiazolyloxy acetamides of formula (I) ##STR1## in which n is the numbers 1 or 2, R1 is hydrogen or possibly substituted alkyl, alkenyl, alkinyl or aralkyl, R... | 10/27/1998 |
| 5736555 | Heterocyclic compounds and their use as angiotensin antagonists | 04/07/1998 |
| 5736561 | Vascular hypertrophy suppressor This invention relates to a method for the prophylaxis or treatment of vascular hypertropy in a mammal by administering a pharmaceutically effective amount of a compound represented by the formula (I): ##STR1## wherein ring W is a nitrogen-containing... | 04/07/1998 |
