Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 8188292 | Insecticidal -substituted (heteroaryl)alkyl sulfilimines N-Substituted (heteroaryl)alkyl sulfilimines are effective at controlling insects. ... | 05/29/2012 |
| 7786310 | Small molecule transcriptional activation domains The present invention relates to gene regulation. In particular, the present invention provides small molecule activation domain compositions and methods of making the same. The present invention further provides methods of regulating gene expression using the novel... | 08/31/2010 |
| 7425635 | Prodrugs and conjugates of thiol- and selenol-containing compounds and methods of use thereof Disclosed are compounds having the formula wherein R1 is hydrogen, an alkyl group, an aryl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aralkyl group, or ═O, ... | 09/16/2008 |
| 7413578 | Colorants comprising cationic azacyanine dyes The present invention relates to agents comprising cationic azacyanine dyes of the formula (I) for coloring keratin fibers, such as, for example, wool, silk or furs and in particular human hair (where X1 is N—R1, O or S a... | 08/19/2008 |
| 7410507 | Use of cationic azacyanine dyes for coloring keratin fibers The present invention relates to the use of cationic azacyanine dyes of the formula (Ia) or (Ib) for coloring keratin fibers, and to a method of coloring hair with various degrees of damage. ... | 08/12/2008 |
| 7407972 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade The present invention provides compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thro... | 08/05/2008 |
| 7402677 | Fluorescent through-bond energy transfer cassettes based on xanthine and pyronin derivatives A TBET cassette including at least one xanthine- or pyronin-based compound as a donor or acceptor is disclosed. Also, a method of TBET cassette design in which four criteria may be used is provided. TBET cassettes may be used to label biological molecules, in clothi... | 07/22/2008 |
| 7387887 | Nucleic acid melting analysis with saturation dyes Methods are provided for nucleic acid analysis wherein a target nucleic acid is mixed with a dsDNA binding dye to form a mixture. Optionally, an unlabeled probe is included in the mixture. A melting curve is generated for the target nucleic acid by measuring fluores... | 06/17/2008 |
| 7374583 | Cationic azacyanine dyes and coloring agents containing said dyes The present invention relates to agents containing cationic azacyanine dyes having formula (I) for dyeing fibers, such as, for example, keratin fibers, wool, silk or fleeces, and in particular human hair, as well as to new asymmetrical azacyanine dyes. | 05/20/2008 |
| 7361755 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines This invention pertains to a novel process for preparing sterically hindered N-substituted alkyloxyamines from alkenes by the transition-metal-catalyzed reaction of a intermediate alkylborane with a sterically hindered nitroxyl radical. ... | 04/22/2008 |
| 7323571 | Heterodimeric dye composition This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful ... | 01/29/2008 |
| 7320960 | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, su... | 01/22/2008 |
| 7288624 | Inhibitors of interleukin-1β converting enzyme The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmace... | 10/30/2007 |
| 7285558 | Pyrazolo[3,4-d]pyrimidines inhibiting infections Compounds having the general formula and pharmaceutical compositions containing them, and their use in the treatment or prophylaxis of H. pylori infection. ... | 10/23/2007 |
| 7259179 | Kinase inhibitors A compound of the general formula: or pharmaceutically acceptable salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating protein kinase-associated disease states usin... | 08/21/2007 |
| 7256304 | Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these The present invention is to provide a process for preparing a 3-unsubstituted-5-amino-4-nitrosopyrazole compound represented by the formula (1): wherein R1 represents a hydroge... | 08/14/2007 |
| 7256275 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation This invention pertains to the field of combination oligomers, including the block synthesis of combination oligomers in the absence of a template, as well as related methods, kits, libraries and other compositions. ... | 08/14/2007 |
| 7241897 | Process for preparing cyanine dye labeling reagents This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful ... | 07/10/2007 |
| 7238795 | Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses The present invention is in the field of nucleic acid binding compounds comprising 7-substituted 7-deaza-8aza-2,6-diamino-purine bases, compounds useful for the preparation of such compounds, various uses thereof and methods for the determination of nucleic acids us... | 07/03/2007 |
| 7176164 | 1,3-selenazolin derivatives and process for preparing the same A process for preparing novel 1,3-selanazolin derivatives represented by chemical formula 1 at high yield. This process includes a step of reacting a selenourea and an α-haloacyl halide in a solvent and in the presence of a catalyst | 02/13/2007 |
| 7169529 | Compound, photosensitive composition, lithographic printing plate precursor, and method of forming image A compound having a novel structure and a photo-sensitive composition comprising (i) the novel compound as a sensitizing dye, (ii) an activator compound generating at least one of a radical and an acid by interacting the activator compound with light absorption of t... | 01/30/2007 |
| 7166715 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds The invention provides an asymmetric cyanine dye compound having the structure including substituted forms thereof, wherein, at least one of R1 and R2 is linking group, X is O, S, or Se, and... | 01/23/2007 |
| 7151104 | Pyrazolopyridines as cyclin dependent kinase inhibitors In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyridine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of p... | 12/19/2006 |
| 7138483 | Monomers, conjugated polymers and electronic devices using such polymers The energy levels (HOMO, LUMO) of the conjugated polymer are tuned independently, so that an energy match on both sides of the device can be accomplished while keeping the emission color in the blue region. Such polymers can be formed by polymerization of a mixture ... | 11/21/2006 |
| 7094896 | Diaminothiazoles having antiproliferative activity Disclosed are novel diaminothiazoles that are selective inhibitors of Cdk4. These compounds and their pharmaceutically acceptable salts and esters are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and... | 08/22/2006 |
| 7045360 | Method for analysis of reaction products The present invention provides methods, compounds, and kits useful in the analysis of reaction products and components of reaction mixtures, and in certain embodiments for the rapid and simultaneous determination of enantiomeric ratios, percent conversions, and abso... | 05/16/2006 |
| 7041145 | Fuel comprising an emulsion between water and a liquid hydrocarbon Fuel made from an emulsion between water and a liquid hydrocarbon and polymeric surfactant, used to stabilize the emulsion, obtainable by (a) reacting (i) at least one polyolefin oligomer functionalized with at least one group deriving from a dicarboxylic acid, or a... | 05/09/2006 |
| 7006215 | Shaped illumination geometry and intensity using a diffractive optical element A method and apparatus to illuminate a target. The apparatus can comprise a first lens configured to receive light from the light source, a diffractive optical element configured to receive the light from the first lens and to regulate the light into regulated light... | 02/28/2006 |
| 6936597 | Prodrugs of anticancer agents employing substituted aromatic acids Polymeric prodrugs of the formula: wherein B is selected from the group consisting of OH, leaving groups, residues of amine-containing moieties and a residues of hydroxyl-containing m... | 08/30/2005 |
| 6926885 | In-vivo diagnostic method by means of near infrared radiation This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluoresc... | 08/09/2005 |
| 6921525 | Contrast agents The invention provides a composition of matter of the formula (I): V-L-R where V is an organic group having binding affinity for an angiotensin II receptor site, L is a linker moiety or a bond, and R is a moiety detectable in in vivo imaging of a human or animal bod... | 07/26/2005 |
| 6903125 | Tetrahydro-2H-thiopyran-4-carboxamide derivative A pharmaceutical drug, particularly a novel compound useful for the prophylaxis or therapeutic treatment of various diseases involving infections with viruses of the Herpesviridae family, specifically various herpesvirus infections such as varicella (chicken pox) vi... | 06/07/2005 |
| 6897208 | Benzimidazoles The invention is directed to physiologically active compounds of the general formula (Ix) and compositions containing such compounds, and their prodrugs, and pharmaceutically acceptable salts and solvates of such compo... | 05/24/2005 |
| 6867298 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or a... | 03/15/2005 |
| 6852885 | Production method of high purity organic compound There is provided a method for obtaining a target organic compound such as an alkyladamantyl ester efficiently by purifying a crude organic compound which contains, as impurities, sublimable materials which start to sublime at temperatures lower than a boiling point... | 02/08/2005 |
| 6838439 | Heterocytes as inhibitors of leucocyte adhesion and as VLA-4 antagonists The present invention relates to compounds of the formula I which are inhibitors of the adhesion and migration of leucocytes and/or antagonists of the adhesion receptor VLA-4 which belongs to the group of integrins. Th... | 01/04/2005 |
| 6800380 | Organometallic luminescent materials and organic electroluminescent device containing same An organometallic luminescent material comprising the compound of formula (I) of the present invention can emit pure blue light and have high thermal stability: wherein, M1 is a monovalent or tetravalen... | 10/05/2004 |
| 6797522 | Synthetic receptors The invention is directed to synthetic receptor(s) which comprises a polyfunctional organic template covalently linked to two or more oligomers which may independently be the same or different and may independently be straight chain, cyclic or branched. The template... | 09/28/2004 |
| 6790953 | Ether compounds The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a compo... | 09/14/2004 |
| 6755872 | Dyeing agent for keratinous fibers A coloring composition and a method of coloring keratin-containing fibers are provided. The coloring composition contains a mixture of and/or a reaction product of at least one heteroaromatic aldehyde or ketone and at least one aromatic and/or heteroaromatic nitroam... | 06/29/2004 |
