...that two musicians were responsible for the invention of color print film? Fascinated by photography, Leopold Godowsky and Leopold Mannes worked together to produce an easy-to-use, practical color film. They worked full time as music teachers and gave concerts while experimenting during their off hours in Mannes' kitchen. Their success earned them full-time, well-paying jobs at Kodak and their efforts resulted in Kodachrome film, which was introduced in 1935.
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| Number | Title | Issue Date |
| 7947839 | Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use Bis 1,8 naphthalimide compounds including antibody drug conjugate (ADC) are described. Pharmaceutical compositions comprising an effective amount of a 1,8 bis-naphthalimide compound for treatment of hyperproliferative disorders and other disorders are described. Met... | 05/24/2011 |
| 7868173 | Prodrugs of benzoquinolizine-2-carboxylic acid The instant invention relates to novel prodrugs of optically pure benzoquinolizine-2-carboxylic acid and pharmaceutical compositions that include the prodrugs. In particular, the present invention relates to the sulfonic acid salts of L-alanine and L-valine prodrugs... | 01/11/2011 |
| 7410746 | Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition The present invention provides a radical generator having a naphthalimide structure or a crosslinking agent and a photosensitive compound having a function as a radical generator. A photoradical polymerization initiator of the present invention comprises a compound ... | 08/12/2008 |
| 7393956 | Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides A process for preparing perylene-3,4:9,10-tetracarboxylic diimides of the general formula I comprising dimerizing a naphthalene-1,8-dicarboximide of the formula II ... | 07/01/2008 |
| 7358362 | Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis A process for preparing terylene-3,4:11,12-tetracarboximides I where the variables are each defined as follows: R, R′ are each independently hydrogen; if desired substituted alkyl or cyc... | 04/15/2008 |
| 7282575 | Functional peptide nucleic acid monomer and process for producing the same A compound represented by the general formula (I) below: In the formula, A is as defined in the specification and B denotes where n is an integer of 1 to 4, ... | 10/16/2007 |
| 7217465 | Pyran derivative A light-emitting compound that can be easily applied to vacuum vapor deposition and exhibit long wavelength light is disclosed. Further, a light-emitting element without inferior luminescence properties due to the carbonization of a light-emitting compound during va... | 05/15/2007 |
| 7148352 | Method of inhibiting neurotrophin-receptor binding The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor to p75... | 12/12/2006 |
| RE39265 | Heteroarylpiperidines, and their use as antipsychotics and analgetics Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. The compound... | 09/05/2006 |
| 6881842 | Process for producing tricyclic fused heterocyclic derivative A process for easily and industrially advantageously producing both a tricyclic fused heterocyclic derivative having acetylcholinesterase inhibitory activity and an intermediate for the derivative. The process for producing the target compounds comprises the followi... | 04/19/2005 |
| 6844089 | Organic red electro-luminescent device and dopant The invention relates to an electroluminescent device, in which the luminescent layer contains a luminescent compound and a compound of the general formula I as doping agent, wherein B is an unsaturated carbocyclic or heterocyclic 4-8-link ring, which can also conta... | 01/18/2005 |
| 6559306 | Dye compounds This invention relates to new fluorescent or non-fluorescent dye compounds having a terminal hydroxy, carboxylic acid/ester or amino group and a process for their preparation. The new fluorescent or non-fluorescent dye compounds are useful as colorants fo... | 05/06/2003 |
| 6486169 | Botanical drug for treatment and prevention of alzhimer's disease The present invention related to safe botanical drug for treatment and prevention of Alzheimer's disease. Specifically, this invention proves a safe botanical drug, Huperzine (HUE) and Clausenamide (CLE) and their preparation. HUE has the following pharma... | 11/26/2002 |
| 6380193 | Fused tricyclic compounds, methods and compositions for inhibiting PARP activity A compound of formula I: ##STR1## or a pharmaceutically acceptable salt, hydrate, ester, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof.... | 04/30/2002 |
| 6372910 | Process for the manufacture of 1,8-naphthalimide A process for preparing 1,8-naphthalimide by reacting 1,8-naphthalic anhydride with ammonia in an aqueous solution under atmospheric pressure at 60 to 100° C.... | 04/16/2002 |
| 6362181 | Isoquinolones Benzo[de]isoquinoline-1,3-diones which are selective inhibitors of bacterial DNA gyrase and DNA topoisomerase useful in antibacterial agents are described as well as methods for their preparation and formulation. Novel intermediates useful in the preparat... | 03/26/2002 |
| 6288232 | Synthesis of pyrazolinylnaphthalic acid derivatives The invention pertains to a method for preparing derivatives of the pyrazolinylnaphthalic acid having the general formula ##STR1## where Ar1 and Ar2 are unsubstituted or substituted phenyl radicals bearing in the para position an alk... | 09/11/2001 |
| 6210608 | Naphthopyrans and phenanthropyrans annelated in C5-C6 with a bicycle group and compositions and (co) polymer matrices containing them The invention relates to novel naphthopyran- and phenanthropyran-type compounds having a carbobicycle annelated in 5,6-position. These compounds have formula (I) given below: ##STR1## These compounds (I) have interesting photochromic properties. The inven... | 04/03/2001 |
| 6048869 | Tricyclic compounds The novel compounds of the present invention are those of structural formula I: ##STR1## or a pharmaceutically acceptable salt, ester, or stereoisomer thereof, which are inhibitors of 5-reductase. The compounds of formula I are useful in ... | 04/11/2000 |
| 5998405 | Fused tropane-derivatives as neurotransmitter reuptake inhibitors The present invention discloses compounds of the formula, or any of its enantiomers or any mixture thereof, a pharmaceutically acceptable addition salt thereof or the N-oxide thereof wherein X and Y together forms .dbd.O, .dbd.S, .dbd.NOR2, .dbd.CR | 12/07/1999 |
| 5981752 | Tricyclic compounds having fungicidal activity, their preparation and their use Compounds of formula (I): ##STR1## [wherein: R1 represents halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, cycloalkyl, or cycloalkyloxy; R2 represents hydrogen or halogen; R3 represents hydrogen, alkyl, or cycloalkyl; ... | 11/09/1999 |
| 5854277 | Thiophenebutanoic acid derivatives as matrix metalloprotease inhibitors Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula ##STR1## wherein each T... | 12/29/1998 |
| 5840903 | 4-aminomethyl-1-azaadamantane derived benzamides This invention relates to compounds of the formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein Z is selected from the group consisting of ##STR2## R1 is alkoxy of one to six carbon atoms; R2, R3 | 11/24/1998 |
| 5776963 | 3-(heteroaryl)-1-(2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1-(2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. D... | 07/07/1998 |
| 5773618 | Tricyclic compounds having fungicidal activity, their preparation and their use Compounds of formula (I): ##STR1## wherein: R1 represents halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, cycloalkyl, or cycloalkyloxy; R2 represents hydrogen or halogen; R3 represents hydrogen, alkyl, or cycloalkyl;... | 06/30/1998 |
| 5760029 | Spirocycle integrin inhibitors This invention relates to novel heterocycles, including (S)-2-phenylsulfonylamino-3-8-(2-pyridinylaminomethyl)-!-1-oxa-2-azaspi ro-4,5!-dec-2-en-3-yl!carbonylamino! propionic acid, which are useful as antagonists of the v ଲ | 06/02/1998 |
| 5733648 | Organic compounds suitable as reactive diluents, and binder precursor compositions including same Organic compounds having at least one ethylenically-unsaturated group are described, the organic compounds being suitable for use in coatable compositions as reactive diluents; compounds of the invention preferably have a divalent organic linking moiety d... | 03/31/1998 |
| 5717098 | Process for the preparation of azanoradamantane benzamides A process for the preparation of a γ-lactone of the formula ##STR1## which can be used to produce a single enantiomer of aminoazanoradamantane which is coupled to aromatic acid moieties to produce compounds useful as 5-HT agonists or antagonists.... | 02/10/1998 |
| 5679689 | Quinolone- and naphthyridonecarboxylic acid derivatives Disclosed are new quinolone- and naphthyridonecarboxyclic acid derivatives of the formula: ##STR1## wherein T represents a radical of the formula: ##STR2## and the other radicals are as disclosed herein, for example, the compound 7-(3a-amin... | 10/21/1997 |
| 5663449 | Intermediate compounds in the synthesis of heteroarylpiperidines, pyrrolidines and piperazines Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. D... | 09/02/1997 |
| 5654466 | Process for the preparation of a disubstituted 2,5-diamino-3-hydroxyhexane Intermediates and processes are disclosed which are useful for the preparation of a substantially pure compound of the formula: ##STR1## wherein R6 and R7 are each hydrogen or R6 and R7 are independently se... | 08/05/1997 |
| 5654319 | N-[(4-heteroaryl-1-piperidinyl)alkyl]-2,3-naphthalimides and related compounds and their therapeutic utility Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. D... | 08/05/1997 |
| 5654431 | 5-alkoxy tryptamine derivatives Novel 5-alkoxy tryptamine derivatives are provided, corresponding to the general formula: ##STR1## in which R may be alkaline, X may be amino, and Y is various N-heterocyclic or N-branched chain moieties. The compounds show selective binding to ... | 08/05/1997 |
| 5648363 | N-[(4-heteroaryl-1-piperidinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2H) - diones and related compounds and their therapeutic utility Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents, the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. D... | 07/15/1997 |
| 5639764 | 2-[(4-heteroaryl)-1-piperidinyl)alkyl]-1,3-indandiones and related compound and their therapeutic utility Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents, the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. D... | 06/17/1997 |
| 5637710 | Intermediate compounds in the synthesis of heteroarylpiperidines and piperazines Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. D... | 06/10/1997 |
| 5625092 | Process for the preparation of a substituted 2.5-diamino-3-hydroxyhexane Intermediates and processes are disclosed which are useful for the preparation of a substantially pure compound of the formula: ##STR1## wherein R6 and R7 are each hydrogen or R6 and R7 are independently se... | 04/29/1997 |
| 5622962 | 5-reductase inhibitors A series of benzoquinolin-3-ones are pharmaceuticals effective in treating conditions consequent on both Type I and Type II 5-reductase.... | 04/22/1997 |
| 5622961 | 5-reductase inhibitors A series of benzoquinolin-3-ones are pharmaceuticals effective in treating conditions consequent on both Type I and Type II 5-reductase.... | 04/22/1997 |
| 5616589 | Bis-naphthalimides for the treatment of cancer Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical... | 04/01/1997 |