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| Number | Title | Issue Date |
| 7098219 | Inhibitors of cellular efflux pumps of microbes Compounds are described which are efflux pump inhibitors of cellular efflux pumps of microbes. Also described are methods of preparing such compounds, methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.... | 08/29/2006 |
| 6962925 | Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors A fully and partially reduced benzo(c)quinolizine compound of formula (1): ... | 11/08/2005 |
| 6908931 | Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MT2 receptor and are useful as chronobiotic and sleep agents. ... | 06/21/2005 |
| 6864028 | Di-hydrazone based charge transport compounds Improved organophotoreceptors have: (a) a charge transport compound having the formula where R1 and R2 are, independently, an (N,N-disubstituted) arylami... | 03/08/2005 |
| 6727261 | Pyrido[2,1-A]Isoquinoline derivatives The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification, and pharmaceutically accept... | 04/27/2004 |
| 6333425 | Malononitrile-derivative anion salts, and their uses as ionic conducting materials The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M+m in... | 12/25/2001 |
| 6242450 | 5-HT1F antagonists This invention provides 5-HT1f antagonists of Formula I: ##STR1## where AR1, AR2, R, and R' are as defined in the specification.... | 06/05/2001 |
| 6013653 | Processes for producing pyridoindole derivatives A process for producing pyridiondole derivatives represented by general formula (III) or their salts (wherein R1 represents hydrogen, lower alkyl or lower alkenyl; R2 represents hydrogen, lower alkyl or halogeno; and R3 re... | 01/11/2000 |
| 5837703 | Amino-alcohol substituted cyclic compounds Therapeutic compounds have the formula: (X)j-(core moiety), j being an integer from one to three, the core moiety comprising a core moiety, the core moiety being a heterocycle having one ring or two-fused rings, each ring having five or six ring atoms, A being... | 11/17/1998 |
| 5760029 | Spirocycle integrin inhibitors This invention relates to novel heterocycles, including (S)-2-phenylsulfonylamino-3-8-(2-pyridinylaminomethyl)-!-1-oxa-2-azaspi ro-4,5!-dec-2-en-3-yl!carbonylamino! propionic acid, which are useful as antagonists of the v ଲ | 06/02/1998 |
| 5624929 | Pyrroloquinoline and pyrrolophenothiazine carboxamides and related compounds Compounds of the formula ##STR1## wherein the broken line represents an optional double bond; X is O, S, CH2 or CH2 CH2 ; R1 is selected from the group consisting of hydrogen, halogen, C1 -C... | 04/29/1997 |
| 5173493 | Pyridoindole derivatives and processes for preparation thereof The invention relates to compounds for treatment of nausea and vomiting, of the formula ##STR1## wherein R1 is hydrogen, lower alkyl, lower alkenyl or N,N-di(lower)alkylaminomethyl, R2 is hydrogen, lower alkyl or halogen, R... | 12/22/1992 |
| 5164400 | Pyrroloquinoline compounds The invention relates to a compound of the formula: ##STR1## in which R1 and R2 are each hydrogen or lower alkyl, R3 is aryl or unsaturated, 5- or 6-membered heterocyclic group containing a sulfur atom, each of which may b... | 11/17/1992 |
| 5141945 | Pyridoindole derivatives and processes for preparation thereof Compounds of the formula: ##STR1## wherein R1 is hydrogen, lower alkyl or lower alkenyl, R2 is hydrogen, lower alkyl, or halogen, R3 is imidazolyl or pyridyl, each of which may have suitable substituents, and R4 | 08/25/1992 |
| 5097034 | Triarylmethane color formers Color formers of the formula ##STR1## in which X1 denotes hydroxyl, alkoxy, alkenyloxy, aralkoxy, cycloalkoxy, aryloxy or acyloxy, R1 denotes hydrogen, halogen, alkyl or alkoxy, R2 denotes hydrogen, alkoxy, aralkoxy, arylo... | 03/17/1992 |
| 4808567 | Divinyl compounds and chromogenic recording-material prepared by using thereof Disclosed herein are novel divinyl compounds represented by the formula (I): ##STR1## and a recording-material prepared by utilizing the divinyl compounds. The present divinyl compound is in itself almost colorless, extremely stable in the atmos... | 02/28/1989 |
| 4550114 | Benzoquinolizines as 2 -adrenoceptor antagonists The invention concerns benzoquinolizines of general formula ##STR1## and their pharmaceutically acceptable acid addition salts. In the formula R1 and R2 which may be the same or different each represent hydrogen, lower alkyl, lo... | 10/29/1985 |
| 4259493 | Perhalomethylcarbinol-substituted phenol and naphthol sulfamphthaleins The present invention is concerned with novel 3,3-disubstituted-sulfam(na)phthaleins wherein one of the 3-substituents is derived from a 1-naphthol or a phenol substituted in the 2-position with a perhalomethylcarbinol group and wherein the N atom of the ... | 03/31/1981 |
| 4257954 | Novel compounds, processes and marking systems Mono and bis substituted (arylsulfonyl)alkanes useful as color formers, particularly in carbonless duplicating and thermal marking systems, are prepared by the interaction of the appropriate aldehyde or dialdehyde with the appropriate aryl or heterocyclic... | 03/24/1981 |
| 4255578 | Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives The present invention is concerned with a method of synthesizing certain ##STR1## 3-disubstituted sulfam(na)phthalein compounds useful as pH-sensitive indicator dyes and with intermediates useful in the preparation of said compounds. The subject meth... | 03/10/1981 |
| 4157914 | Derivatives of 1,3,4-oxadiazole and electrophotographic elements containing same 1,3,4-OXADIAZOLE DERIVATIVES EXPRESSED BY THE GENERAL FORMULA ##STR1## wherein R represents cyanophenyl, nitrophenyl, dialkylaminophenyl (wherein alkyl has 1-4 carbon atoms), julolidyl, N-alkylcarbazolyl (wherein alkyl has 1-4 carbon atoms) or ferroc... | 06/12/1979 |
| 4133812 | Process for producing benzo (a) quinolizine derivatives Compounds are prepared with anti-amoeba activity of the following formula: ##STR1## wherein R1 equals R2 and each is lower alkyl and R3 and R4 are each lower alkyl, with the proviso that R1 and R... | 01/09/1979 |
| 4002631 | Tetrahydroquinoline or jujolidine derivative of a lactone compound of pyridine-carboxylic acid A lactone compound represented by the following formula ##STR1## or ##STR2## or a mixture thereof, wherein R1, R2, R3, R4 and A are as defined hereinafter and a process for preparing the same are discl... | 01/11/1977 |