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Class 546/96 - Additional polycyclo ring system having ring nitrogen (e.g., emetine, etc.)


Subclass of Class 546 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain an additional polycyclo ring system
No. of patents: 23
Last issue date: 08/29/2006


NumberTitleIssue Date
7098219Inhibitors of cellular efflux pumps of microbes
Compounds are described which are efflux pump inhibitors of cellular efflux pumps of microbes. Also described are methods of preparing such compounds, methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds....
08/29/2006
6962925Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors
A fully and partially reduced benzo(c)quinolizine compound of formula (1): ...
11/08/2005
6908931Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists
The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MT2 receptor and are useful as chronobiotic and sleep agents. ...
06/21/2005
6864028Di-hydrazone based charge transport compounds
Improved organophotoreceptors have: (a) a charge transport compound having the formula where R1 and R2 are, independently, an (N,N-disubstituted) arylami...
03/08/2005
6727261Pyrido[2,1-A]Isoquinoline derivatives
The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification, and pharmaceutically accept...
04/27/2004
6333425Malononitrile-derivative anion salts, and their uses as ionic conducting materials
The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M+m in...
12/25/2001
62424505-HT1F antagonists
This invention provides 5-HT1f antagonists of Formula I: ##STR1## where AR1, AR2, R, and R' are as defined in the specification....
06/05/2001
6013653Processes for producing pyridoindole derivatives
A process for producing pyridiondole derivatives represented by general formula (III) or their salts (wherein R1 represents hydrogen, lower alkyl or lower alkenyl; R2 represents hydrogen, lower alkyl or halogeno; and R3 re...
01/11/2000
5837703Amino-alcohol substituted cyclic compounds
Therapeutic compounds have the formula: (X)j-(core moiety), j being an integer from one to three, the core moiety comprising a core moiety, the core moiety being a heterocycle having one ring or two-fused rings, each ring having five or six ring atoms, A being...
11/17/1998
5760029Spirocycle integrin inhibitors
This invention relates to novel heterocycles, including (S)-2-phenylsulfonylamino-3-›››8-(2-pyridinylaminomethyl)-!-1-oxa-2-azaspi ro-›4,5!-dec-2-en-3-yl!carbonylamino! propionic acid, which are useful as antagonists of the ଱v ଲ
06/02/1998
5624929Pyrroloquinoline and pyrrolophenothiazine carboxamides and related compounds
Compounds of the formula ##STR1## wherein the broken line represents an optional double bond; X is O, S, CH2 or CH2 CH2 ; R1 is selected from the group consisting of hydrogen, halogen, C1 -C...
04/29/1997
5173493Pyridoindole derivatives and processes for preparation thereof
The invention relates to compounds for treatment of nausea and vomiting, of the formula ##STR1## wherein R1 is hydrogen, lower alkyl, lower alkenyl or N,N-di(lower)alkylaminomethyl, R2 is hydrogen, lower alkyl or halogen, R...
12/22/1992
5164400Pyrroloquinoline compounds
The invention relates to a compound of the formula: ##STR1## in which R1 and R2 are each hydrogen or lower alkyl, R3 is aryl or unsaturated, 5- or 6-membered heterocyclic group containing a sulfur atom, each of which may b...
11/17/1992
5141945Pyridoindole derivatives and processes for preparation thereof
Compounds of the formula: ##STR1## wherein R1 is hydrogen, lower alkyl or lower alkenyl, R2 is hydrogen, lower alkyl, or halogen, R3 is imidazolyl or pyridyl, each of which may have suitable substituents, and R4
08/25/1992
5097034Triarylmethane color formers
Color formers of the formula ##STR1## in which X1 denotes hydroxyl, alkoxy, alkenyloxy, aralkoxy, cycloalkoxy, aryloxy or acyloxy, R1 denotes hydrogen, halogen, alkyl or alkoxy, R2 denotes hydrogen, alkoxy, aralkoxy, arylo...
03/17/1992
4808567Divinyl compounds and chromogenic recording-material prepared by using thereof
Disclosed herein are novel divinyl compounds represented by the formula (I): ##STR1## and a recording-material prepared by utilizing the divinyl compounds. The present divinyl compound is in itself almost colorless, extremely stable in the atmos...
02/28/1989
4550114Benzoquinolizines as ଱2 -adrenoceptor antagonists
The invention concerns benzoquinolizines of general formula ##STR1## and their pharmaceutically acceptable acid addition salts. In the formula R1 and R2 which may be the same or different each represent hydrogen, lower alkyl, lo...
10/29/1985
4259493Perhalomethylcarbinol-substituted phenol and naphthol sulfamphthaleins
The present invention is concerned with novel 3,3-disubstituted-sulfam(na)phthaleins wherein one of the 3-substituents is derived from a 1-naphthol or a phenol substituted in the 2-position with a perhalomethylcarbinol group and wherein the N atom of the ...
03/31/1981
4257954Novel compounds, processes and marking systems
Mono and bis substituted (arylsulfonyl)alkanes useful as color formers, particularly in carbonless duplicating and thermal marking systems, are prepared by the interaction of the appropriate aldehyde or dialdehyde with the appropriate aryl or heterocyclic...
03/24/1981
4255578Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives
The present invention is concerned with a method of synthesizing certain ##STR1## 3-disubstituted sulfam(na)phthalein compounds useful as pH-sensitive indicator dyes and with intermediates useful in the preparation of said compounds. The subject meth...
03/10/1981
4157914Derivatives of 1,3,4-oxadiazole and electrophotographic elements containing same
1,3,4-OXADIAZOLE DERIVATIVES EXPRESSED BY THE GENERAL FORMULA ##STR1## wherein R represents cyanophenyl, nitrophenyl, dialkylaminophenyl (wherein alkyl has 1-4 carbon atoms), julolidyl, N-alkylcarbazolyl (wherein alkyl has 1-4 carbon atoms) or ferroc...
06/12/1979
4133812Process for producing benzo (a) quinolizine derivatives
Compounds are prepared with anti-amoeba activity of the following formula: ##STR1## wherein R1 equals R2 and each is lower alkyl and R3 and R4 are each lower alkyl, with the proviso that R1 and R...
01/09/1979
4002631Tetrahydroquinoline or jujolidine derivative of a lactone compound of pyridine-carboxylic acid
A lactone compound represented by the following formula ##STR1## or ##STR2## or a mixture thereof, wherein R1, R2, R3, R4 and A are as defined hereinafter and a process for preparing the same are discl...
01/11/1977
 
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