Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
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| Number | Title | Issue Date |
| 8101759 | Acenaphthopyridine derivative, material of light-emitting element, light-emitting element, light-emitting device, and electronic appliance It is an object to provide a new compound which is suitable for a material of an electron-transporting layer of a light-emitting element. In particular, it is an object to provide a compound which can be used for forming a light-emitting element capable of emitting ... | 01/24/2012 |
| 7408072 | Heteropolycyclic compound and dye The present invention provides heteropolycyclic compounds represented by General Formulae (1) and (2): wherein R1 is a straight- or branched-chain C1-C10 alkyl group or the like; R2 | 08/05/2008 |
| 7354926 | Molecules derived from noraporphine The invention concerns novel molecules derived from noraporphine, as well as cosmetic and dermopharmaceutical compositions containing one or several of said derivatives, alone or combined with a plant extract, in particular glaucium flavum, and particularly p... | 04/08/2008 |
| 7332503 | Aporphine esters and their use in therapy New aporphine derivatives are disclosed which have formula (I) and the physiologically acceptable salts thereof. Said derivatives may be used for the treatment of Parkinson's disease, hemicrania, restless legs syndrome (RLS), sexual dysfunction in men and women, hyp... | 02/19/2008 |
| 7323566 | Radiopharmaceutical and methods of synthesis and use thereof A novel group of apomorphine derivatives are provided that are well suited as radioimaging agents upon incorporation of radionuclides. Through reaction of D ring sites, the less reactive sites of the apomorphine A ring is modified in ways previously unattainable. | 01/29/2008 |
| 7291429 | Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives Naphthalenetetracarboxylic acid diimide derivatives and an electrophotographic photoconductive material containing the naphthalenetetracarboxylic acid diimide derivatives. The naphthalenetetracarboxylic acid diimide derivatives have a structure represented by the fo... | 11/06/2007 |
| 7262298 | 4-hydroxybenzomorphans 4-Hydroxybenzomorphans containing carboxamide or thiocarboxamide at the 3-position are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. ... | 08/28/2007 |
| 7238705 | Aporphine esters and their use in therapy New aporphine derivatives are disclosed which have formula (I) and the physiologically acceptable salts thereof. Said derivatives may be used for the treatment of Parkinson's disease, hemicrania, restless legs syndrome (RLS), sexual dysfunction in men and women, hyp... | 07/03/2007 |
| 7220754 | Mono-ester and asymmetrically substatuted di-ester pro-drugs of dopamide D1 receptor agonists Mono-ester and asymmetrically substituted diesters of dihydrexidine, dinapsoline and A-86929 and substituted derivatives thereof are described. The novel ester/diester derivatives exhibit improved pharmacokinetic characteristics relative to their unesterified parent... | 05/22/2007 |
| 7060829 | Colorant compounds containing copolymerizable vinyl groups Disclosed are novel colorant compounds which contain one or more ethylenically-unsaturated (vinyl), photopolymerizable radicals which may be copolymewrized (or cured) with ethylenically-unsaturated monomers to produce colored compositions such as colored acrylic coa... | 06/13/2006 |
| 7057044 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof The invention provides aporphine and oxoaporphine compounds that have endothelial nitric oxide synthase (eNOS) maintaining or enhancing activities and may be used to manufacture a medicaments for preventing or treating ischemic diseases in human and mammal, and the ... | 06/06/2006 |
| 7030244 | Colorant compounds containing copolymerizable vinyl groups Disclosed are novel colorant compounds which contain one or more ethylenically-unsaturated (vinyl), photopolymerizable radicals which may be copolymewrized (or cured) with ethylenically-unsaturated monomers to produce colored compositions such as colored acrylic coa... | 04/18/2006 |
| 7015327 | Anthrapyridone compounds, water-base magenta ink compositions and method of ink-jet recording New anthrapyridone compounds represented by the general formula (14): {wherein R represents a hydrogen atom, an alkyl group (optionally substituted with mono- or di-alkylamino group), a lower alkyl group (optionally subst... | 03/21/2006 |
| 7011701 | Dye and ink jet printing ink A dye is disclosed, which is represented by the following formula: wherein Z is an atomic group necessary to form a 6-membered nitrogen containing aromatic ring; R11 is a hydrogen bonding group; R12 | 03/14/2006 |
| 6902607 | Anthrapyridone compound, water-based magenta ink composition, and method of ink-jet recording The ink composition comprises as its coloring matter component a water-based magenta composition containing anthrapyridone compound represented by the formula (1): wherein R represents hydrogen atom or methyl gr... | 06/07/2005 |
| 6858733 | Compounds for generating chemiluminescence with a peroxidase Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a peroxidase enzyme and a pe... | 02/22/2005 |
| 6645975 | Process for the preparation of dinaposoline The present invention relates to a novel process for the preparation of compounds of the formula ##STR1## wherein R1, R2, R4, R5, R6 and A are as defined herein, and to certain derivations of Formula ... | 11/11/2003 |
| 6433172 | Steroespecific preparation of chiral 1-aryl- and 1-heteroaryl-2-substituted ethyl-2-amines This invention is directed to methods for stereospecifically preparing [(1-optionally substituted aryl)- or (1-optionally substituted heteroaryl)]-2-substituted ethyl-2-amines, having chirality at the 2-position, and to intermediates to the substituted et... | 08/13/2002 |
| 6372756 | Epimorphian compound and its use A novel compound N-demethyl-sinomenine, a metabolite of the anti-arthritic alkaloid sinomenine, has been identified and characterized. The compound may be incorporated in a pharmaceutical composition and may be administered to patients for treatment of va... | 04/16/2002 |
| 6348596 | Non-fluorescent asymmetric cyanine dye compounds useful for quenching reporter dyes The invention provides asymmetric cyanine dye compounds having the general formula: ##STR1## including substituted forms thereof, which are non-fluorescent quencher molecules. The invention further provides reporter-quencher dye pairs, wherein the as... | 02/19/2002 |
| 6313134 | Uses of thaliporphine or its derivatives in treatment of cardiac diseases and preparation of same The present invention discloses thaliporphine and its derivatives for the treatment and/or prophylaxis of cardiac diseases, including cardiac arrhythmia, myocardial ischemia or myocardial infarction, and sudden death caused by cardiac arrhythmia or acute ... | 11/06/2001 |
| 6248884 | Extended rhodamine compounds useful as fluorescent labels Extended rhodamine compounds exhibiting favorable fluorescence characteristics having the structure ##STR1## are disclosed. In addition, novel intermediates for synthesis of these dyes are disclosed, such intermediates having the structure ##STR2## I... | 06/19/2001 |
| 6174891 | Antipruritic agent This invention provides an antipruritic comprising an opiate .kappa. receptor agonist as an effective component, a new morphinan quaternary ammonium salt derivative and a new morphinan-N-oxide derivative which are useful in treating pruritus complicated w... | 01/16/2001 |
| 6136818 | Combination of phentolamine and apomorphine for the treatment of human sexual function and dysfunction A method of treating sexual dysfunction comprising administering a therapeutically effective amount of a combination of phentolamine and apomorphine, as well as pharmaceutical compositions and kits useful in those methods, are disclosed.... | 10/24/2000 |
| 5959110 | Fused isoquinolines as dopamine receptor ligands The present invention is directed to a novel dopamine receptor ligands of the formula: ##STR1## pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction o... | 09/28/1999 |
| 5717098 | Process for the preparation of azanoradamantane benzamides A process for the preparation of a γ-lactone of the formula ##STR1## which can be used to produce a single enantiomer of aminoazanoradamantane which is coupled to aromatic acid moieties to produce compounds useful as 5-HT agonists or antagonists.... | 02/10/1998 |
| 5622958 | Enediyne quinone imines and methods of preparation and use thereof A quinone imine enediyne possessing cytotoxic activity towards cancer cells having the general structure: ##STR1## wherein R1, R2 and R3 are independently the same or different and are H, Br, Cl, F, NH2, CO... | 04/22/1997 |
| 5534521 | Benzimidazole compounds This invention relates to compounds useful in treating HT4 and/or HT3 mediated conditions of the formula ##STR1## or a pharmaceutically acceptable salt thereof; pharmaceutical compositions containing the compounds and a method f... | 07/09/1996 |
| 5457206 | Process for preparing intermediates to nizatidine and related compounds The present invention provides a process for preparing a 2-(aminomethyl)-4-thiazolemethanol. The compounds produced by the process of the present invention are useful for synthesizing anti-ulcer compounds such as Nizatidine.... | 10/10/1995 |
| 5258384 | S-11-hydroxy-10-methylaporphine and its biologically active salt forms as 5HT1A inhibitors S-11-hydroxy-10-methylaporphine and its biologically active salt forms are used as 5-HT1A inhibitors. Since these compounds function as 5-HT1A they can be used as an antidote for effects of cocaine and as appetite suppressants. S-11 ... | 11/02/1993 |
| 5245028 | Process for preparing tetracyclic amines useful as cerebrovascular agents Processes for the preparation of a series of tetracyclic amines useful in the treatment and/or prevention of cerebrovascular disorders are disclosed.... | 09/14/1993 |
| 5154887 | Phenalenimine fluorescent dyes and their use in analytical compositions, elements and methods Certain phenalenimine fluorescent compounds represented by the structure ##STR1## wherein R' and R" are independently hydrogen, alkyl, cycloalkyl, aryl or a heterocycle, or R' comprises the carbon and heteroatoms which form a fused ring with the comp... | 10/13/1992 |
| 5109136 | Tetracyclic amines useful as cerebrovascular agents A novel series of tetracyclic amines, methods of preparation, compositions containing the amines, and methods for using them in the treatment and/or prevention of cerebrovascular disorders are disclosed.... | 04/28/1992 |
| 5070093 | Tetracyclic amines useful as cerebrovascular agents A novel series of tetracyclic amines, methods of preparation, compositions containing the amines, and methods for using them in the treatment and/or prevention of cerebrovascular disorders are disclosed.... | 12/03/1991 |
| 5001115 | Prodrugs of biologically active hydroxyaromatic compounds Prodrugs of bio-active hydroxyaromatic drugs having the structural formula: A pharmaceutically acceptable prodrug of a biologically active, therapeutically effective hydroxyaromatic drug, said prodrug being selected from the group consisting of, (A) compounds ... | 03/19/1991 |
| 4933324 | Fatty acid-neuroactive drug conjugate as a prodrug The invention involves the formation of a prodrug from a fatty acid carrier and a neuroactive drug. The prodrug is stable in the environment of both the stomach and the bloodstream and may be delivered by ingestion. The prodrug passes readily through the ... | 06/12/1990 |
| 4873349 | Ruthenium catalyst for biarylic coupling; new steganolides A method for forming bridged biaryl compounds via the intramolecular oxidative biarylic coupling of precursor compounds containing two aromatic rings linked via a hydrocarbon chain is disclosed along with the ruthenium catalyst for its implementation and ... | 10/10/1989 |
| 4687773 | (+)-N-N-propylnorapomorphine and selective limbic activity Antidopaminergic agents having selective limbic activity, comprising (S)-enantiomers of aporphine compounds of either the following structures: ##STR1## wherein R1 is lower alkyl, alkyl substituted lower alkyl, alkyl substituted cycloalkyl... | 08/18/1987 |
| 4591587 | Cyclopropyl pyridine compounds useful as calcium channel blockers Novel cyclopropyl pyridine compounds useful as calcium channel blockers, pharmaceutical compositions thereof, and methods of treatment are disclosed.... | 05/27/1986 |
| 4590276 | Process for the preparation of cyclopropyl pyridine compounds useful as calcium channel blockers A novel process for the preparation of cyclopropyl pyridine compounds, which are useful as calcium channel blockers, is disclosed.... | 05/20/1986 |
