Quotables
"This is the patent age of new inventions for killing bodies, and for saving souls. All propagated with the best intentions."
Lord Byron ;
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7745628 | Method for obtaining a pharmaceutically active compound, synthesis intermediates thereof and methods for obtaining them The present invention relates to a method for obtaining Dolasetron that comprises: a) Esterification of the alcohol of formula (IV) with indole-3-carboxylic acid (compound (III)) or a reactive derivative thereof, to give a compound of formula (V), followed by step b... | 06/29/2010 |
| 7608714 | Production of dolasetron The present invention provides an improved process for the preparation of Dolasetron salts, in particularly Dolasetron mesylate. Also provided are intermediates for the process and methods of preparing the intermediates. ... | 10/27/2009 |
| 7101890 | Benzazepine derivatives, drugs containing these and use of the same for producing drugs New derivatives of benzazepine, particularly of benzofuro[3a,3,2,ef][2]benzazepin of the general formula (I) and new compounds of the general formula (III) Dru... | 09/05/2006 |
| 7094786 | Method of treating nausea, vomiting, retching or any combination thereof Methods are disclosed for the treatment of nausea and vomiting in a patient suffering therefrom comprising administering 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine. ... | 08/22/2006 |
| 7045626 | Quinoline derivatives, process for preparing them and use for the treatment of diseases mediated by s-CD23 A compound of formula (I): useful in the treatment and prophylaxis of conditions mediated by s-CD23 ... | 05/16/2006 |
| 7015333 | Process for preparation of imidazolyl compounds A method for preparing an imidazolyl compound corresponding to the formula (I) by reacting a compound corresponding to formula (II) with a compound corresponding to formula... | 03/21/2006 |
| 6908927 | Pyridopyranoazepine derivatives, their preparation and their therapeutic application The invention relates to pyridopyranoazepine derivatives, to pharmaceutical compositions containing them, to process for preparing them, and to the method of use thereof in the treatment or prevention of disorders associated with a dysfunction of the nicotine recept... | 06/21/2005 |
| 6476021 | Compounds having cGMP-PDE inhibitory effect Novel fused tetracyclic heterocyclic compounds having a potent and highly selective effect of inhibiting cyclic GMP phosphodiesterase (cGMP-PDE) and a high safety; a process for producing the same; drugs characterized by containing at least one of these c... | 11/05/2002 |
| 6423842 | Muscarinic agonists and antagonists The present invention provides novel compounds and pharmaceutical compositions thereof useful in the treatment of pain. The compounds of the present invention are azaadamantanes, azanoradamantanes and azahomoadamantanes.... | 07/23/2002 |
| 6365743 | Process for the preparation of enantiomerically pure imidazolyl compounds The invention relates to a method for the preparation of an enantiomerically pure imidazolyl compound of the general formula ##STR1## wherein: n is 0 or 1; m is 1 or 2; R1 is hydrogen, methyl or ethyl; and C* denotes a chiral center; as well as its ... | 04/02/2002 |
| 6346536 | Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same Poly(ADP-ribose) polymerase ("PARP") inhibitors and methods for treating neurodegenerative diseases, neural tissue damage related to cerebral ischemia and reperfusion injury, and cardiovascular in an animal.... | 02/12/2002 |
| 6251916 | Muscarinic agonists and antagonists The present invention provides novel compounds and pharmaceutical compositions thereof useful in the treatment of pain. The compounds of the present invention are azaadamantanes, azanoradamantanes and azahomoadamantanes.... | 06/26/2001 |
| 5886005 | 4-Aza-19-norandrostane derivatives Compounds of the formula ##STR1## are inhibitors of 5-reductase and are useful alone or in combination with other active agents for the treatment of hyperandrogenic disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern ... | 03/23/1999 |
| 5840903 | 4-aminomethyl-1-azaadamantane derived benzamides This invention relates to compounds of the formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein Z is selected from the group consisting of ##STR2## R1 is alkoxy of one to six carbon atoms; R2, R3 | 11/24/1998 |
| 5831095 | Synthesis of 5-aminocarbonyl-5H-dibenzoa,d!cyclohepten-5,10-imine A powerful new anti-convulsant and anti-ischemic pharmaceutical, 5-aminocarbonyl-5H-dibenzoa,d!cycloheptene-5,10-imine is prepared according to a novel synthesis which converts the starting material, commercially available dibenzosubernone to ADCI witho... | 11/03/1998 |
| 5814642 | Tetracyclic condensed heterocyclic compounds their production, and use A novel compound of the formula ##STR1## wherein Ar represents a tetracyclic fused heterocyclic group which may be substituted; R1 represents H or a hydrocarbon group which may be substituted; Y represents an amino acid or nitrogen-contain... | 09/29/1998 |
| 5739337 | Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo3.2.1!octanes Disclosed are a process and novel compounds useful for preparing compounds of formula I ##STR1## wherein R1 and R2 independently represent hydrogen, inorganic or optionally substituted organic substituents; and R3 is ... | 04/14/1998 |
| 5731317 | Bridged piperidines promote release of growth hormone The present invention is directed to certain novel compounds identified as bridged piperidines of the general structural formula: ##STR1## wherein R1, R1a, R2a, R3, R3a,R4, R5, ... | 03/24/1998 |
| 5686614 | Preparation of chiral 5-aminocarbonyl-5H-dibenzoa,d!cyclohepten-5,10-imines by optical resolution Disclosed are processes for resolving a racemic mixture of 5-aminocarbonyl-5H-dibenzoa,d!cyclohepten-5,10-imines into component enantiomers comprising recrystallizaton of diasteriomeric tartrate salts.... | 11/11/1997 |
| 5663343 | Process for the preparation of enantiomerically pure imidazolyl compounds The invention relates to a method for the preparation of an enantiomerically pure imidazolyl compound of the general formula ##STR1## wherein n is 0 or 1; m is 1 or 2; R1 is hydrogen, methyl or ethyl; and C* denotes a chiral centre; as well as ... | 09/02/1997 |
| 5631264 | Substituted 6,11-ethano-6,11-dihydrobenzo[B]quinolizinium salts and compositions and methods of use thereof Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.... | 05/20/1997 |
| 5624929 | Pyrroloquinoline and pyrrolophenothiazine carboxamides and related compounds Compounds of the formula ##STR1## wherein the broken line represents an optional double bond; X is O, S, CH2 or CH2 CH2 ; R1 is selected from the group consisting of hydrogen, halogen, C1 -C... | 04/29/1997 |
| 5620973 | Tetracyclic condensed heterocyclic compounds and their use A novel compound of the formula ##STR1## wherein Ar represents a tetracyclic fused heterocyclic group which may be substituted; R1 represents H or a hydrocarbon group which may be substituted; Y represents an amino or nitrogen-containing s... | 04/15/1997 |
| 5554620 | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment of neurodegenerative disorders or neurotoxic injuries utilizing them, wherein the substituted 6,11-ethano-6,11-dihy... | 09/10/1996 |
| 5534521 | Benzimidazole compounds This invention relates to compounds useful in treating HT4 and/or HT3 mediated conditions of the formula ##STR1## or a pharmaceutically acceptable salt thereof; pharmaceutical compositions containing the compounds and a method f... | 07/09/1996 |
| 5461057 | Hydro-ethano-indeno-pyridines A compound of formula I ##STR1## wherein X, V, W, Y, Z, R, a, b, c, and d are as described herein. These compounds are useful in the treatment of tumors, allergies, bronchoconstriction and CNS diseases and conditions.... | 10/24/1995 |
| 5196415 | 5-aminocarbonyl-5H-dibenzo[a.d]cyclohepten-5,10-imines for treatment of epilepsy and cocaine addiction This invention is in the field of clinical neurology and relates specifically to compounds, compositions and methods for treatment of patients with generalized epilepsy or partial (symptomatic) epilepsy using compounds of the formula: ##STR1## T... | 03/23/1993 |
| 5098820 | Solid particle dispersions of filter dyes for photographic elements Solid particle dispersions of dyes according to the formula: ##STR1## are disclosed as filter dyes for photograhic elements. In this formula, m is 0 or 1. R1 and R2 are each independently substituted or unsubstituted alkyl or substit... | 03/24/1992 |
| 5082942 | Novel derivatives of tetrahydro-2,3,6,7,1H,5H,11H-(1)benzopyrano(6,7,8,ij)quinolizinone-11 usable as markers of organic compounds for the detection of said compounds by chemiluminescence or fluorescence The invention concerns new derivatives of tetrahydro-2,3,6,7,1H,5H,11H-(1)benzopyrano(6,7,8, ij)quinolizinone in accordance with formula: ##STR1## in which R1 represents a radical having formula: ##STR2## wherein m is equal to 0 ... | 01/21/1992 |
| 5045545 | [(Imidazol-4(and 5)-yl)methyl] tetracyclic ketones having 5-HT3 antagonist activity The invention relates to tetracyclic ketones of the general formula (I) ##STR1## wherein n represents 1, 2 or 3; Im represents an imidazolyl group of the formula: ##STR2## wherein one of the groups represented by R1, R2 and R | 09/03/1991 |
| 4996211 | Substituted dibenzocycloheptenimines The present invention provides a compound of formula (I): ##STR1## or a pharmaceutically acceptable salt thereof, wherein one of R1, R2, R3 and R4 represents a hydrocarbon or hydrocarbyloxycarbonyl group an... | 02/26/1991 |
| 4939136 | New anellated indole derivatives The invention relates to new anellated indole derivatives of general formula 2, ##STR1## wherein p1 R0 is alkyl or alkoxy having 1-4 C-atoms, phenylalkoxy having 1-3 C-atoms in the alkoxy group, hydroxy, halogen, trifluoromethyl, trif... | 07/03/1990 |
| 4906755 | Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds The present invention is directed to a group of esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(3H)-ones and related compounds. The compounds are prepared from the appropriate carboxylic acids and alcohols by standard procedures or, where steric... | 03/06/1990 |
| 4870079 | Derivatives of 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine Fluoro-and hydroxy-derivatives of 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines wherein the substituents are on non-benzenoid carbons are active anticonvulsants and antagonists of N-methyl-D-aspartate.... | 09/26/1989 |
| 4870080 | Polyhydro derivatives of 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine 10,11-Dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imines and derivatives thereof wherein one or the other or both benzo rings are hydrogenated are active anticonvulsants and atagonists of N-methyl-D-aspartate.... | 09/26/1989 |
| 4868191 | Alkaloid compounds, and pharmaceutical compositions containing them Novel alkaloid compounds that are derivatives of methaniminoetheno[d,e]acridine are derived from marine sponges of the genus Dercitus. These compounds and pharmaceutical compositions containing therapeutic effective amounts thereof are useful as antitumor... | 09/19/1989 |
| 4762831 | Antibacterial 1,8-bridged 4-quinolone-3-carboxylic acids A process for the preparation of a 1,8-bridged 4-quinolone-3-carboxylic acid of the formula ##STR1## wherein the substituents are defined hereinbelow. Some of the compound are new. The old and new compounds are antibacterials and promote animal ... | 08/09/1988 |
| 4668803 | Benzafuran derivatives Novel organic compound of the basic formula ##STR1## which have substantial luminescent emission characteristics and advantages.... | 05/26/1987 |
| 4578382 | 4-acylamino-1-azaadamantanes, and compositions for use thereof in medicine The invention relates to 4-acylamino-1-azaadamantanes represented by general formula (I): ##STR1## wherein R represents an alkyl group, a substituted alkyl group, an aryl group or a substituted aryl group, useful in particular, for the treatment ... | 03/25/1986 |
| 4477668 | Process for 5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine (+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine, and its pharmaceutically acceptable salts is useful as an anxiolytic, antidepressant, anticonvulsant, muscle relaxant and in the treatment of mixed anxiety-depression, minimal brain dysfun... | 10/16/1984 |
