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| Number | Title | Issue Date |
| 7435818 | Crystal forms of irinotecan hydrochloride The present invention provides for novel crystalline forms of irinotecan hydrochloride and processes for their preparation, pharmaceutical compositions containing the novel forms and methods for treating metastatic carcinoma of the colon or rectum using same. ... | 10/14/2008 |
| 7396837 | Antitumoral analogs of lamellarins New lamellarins are provided of the general formula III or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof ... | 07/08/2008 |
| 7199130 | Substituted 5,6,6a, 11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid compounds as NMDA-antagonists Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid compounds, and processes for the production thereof, pharmaceutical compositions containing these compounds and the use thereof in treatment methods and for the production of pharmaceut... | 04/03/2007 |
| 7148351 | Fluorescent monomers and tagged treatment polymers containing same for use in industrial water systems Fluorescent monomers are described and claimed which are synthesized by reacting a substituted or non-substituted naphthalic anhydride with an amine and with a moiety containing a polymerizable group. Such monomers are useful for the preparation of tagged treatment ... | 12/12/2006 |
| 7144891 | Benzo[b ]pyrano[3,2- h ]acridin-7-one cinnamate compounds A compound selected from those of formula (I): wherein: X and Y represent a group selected from hydrogen, halogen, alkoxy, nitro, cyano, alkyl, alkenyl, polyhaloalkyl and —NR | 12/05/2006 |
| 7109043 | Fluorescent probe for magnesium ion determination A fluorescent probe for measuring magnesium ion, which can selectively form a complex with magnesium ion in aqueous system is disclosed. The fluorescent probe for measuring magnesium ion according to the present invention has the structure represented by the followi... | 09/19/2006 |
| 7057045 | Process for obtaining 17β-(substituted)-3-oxo-Δ-4-azasteroids and intermediates The 17β-(substituted)-3-oxo-Δ1,2-4-azasteroids (I), wherein R1 is C1–C4 alkyl, OR2, wherein R2 is a C1–C4 alkyl radical, or NR3R4, wherein R3 | 06/06/2006 |
| 6930184 | Functional fluorescent dyes Fluorescent functional dyes represented by the following formulas: wherein R1 is hydrogen or methyl; R2, R3, R4, R5, and R6 are each independently selec... | 08/16/2005 |
| 6867301 | Oxidation process for highly dispersible quinacridone pigments A process for the preparation of a quinacridone comprises oxidation of a 6,13-dihydroquinacridone using hydrogen peroxide, wherein a polymeric dispersant is present in the oxidation reaction mixture. The resulting pigment products exhibit greatly improved dispersibi... | 03/15/2005 |
| 6858733 | Compounds for generating chemiluminescence with a peroxidase Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a peroxidase enzyme and a pe... | 02/22/2005 |
| 6824766 | Biodegradable high molecular weight polymeric linkers and their conjugates The present invention includes polymeric transport systems corresponding to the formula: wherein: R31 is a linear or branched polymer residue; Y10 and Y11 | 11/30/2004 |
| 6784187 | 8-carboxamido-2,6-methano-3-benzazocines 8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is —CH2—OH, —CH2NH2, —NHSO2CH3, and Y is O, S or NOH are useful as analgesi... | 08/31/2004 |
| 6642248 | Benzo[b]pyrano[3,2-h]acridin-7-one compounds A compound selected from those of formula (I): ##STR1## wherein: X and Y represent group selected from hydrogen, halogen, mercapto, cyano, nitro, alkyl, trihaloalkyl, trihaloalkylcarbonylamino, --ORa, --NRaRb, --NRa--C(O)--T1, --O--C(O)--T | 11/04/2003 |
| 6608076 | Camptothecin derivatives and polymeric conjugates thereof Polymeric conjugates of camptothecin derivatives having increased circulating half-lives are disclosed. In preferred aspects, the E ring lactone of the camptothecin derivative is opened and functionalized to allow attachment of a polymer such as PEG in th... | 08/19/2003 |
| 6559306 | Dye compounds This invention relates to new fluorescent or non-fluorescent dye compounds having a terminal hydroxy, carboxylic acid/ester or amino group and a process for their preparation. The new fluorescent or non-fluorescent dye compounds are useful as colorants fo... | 05/06/2003 |
| 6548515 | Dihydrofuro[3,4-b]quinolin-1-one compounds The invention relates to compound of formula (I): ##STR1## wherein: {character pullout} represents a single or double bond, R0 represents hydrogen or hydroxy or alkoxy, R1 and R2, which are identical or different, each represents ... | 04/15/2003 |
| 6521757 | Preparation of fused polycyclic alkaloids by ring closure of azomethine ylides, novel compounds thereof and their use as chemotherapeutic agents A method for the preparation of a compound of general Formula: ##STR1## or pharmaceutically acceptable derivatives and salts, racemates, isomers and/or tautomers thereof comprising cyclizing an azomethine ylide of general Formula: ##STR2## wherein, A... | 02/18/2003 |
| 6503919 | Compounds of 7-oxo-2,3,7,14-tetrahydro-1H-benzo[b]pyrano[3,2-h]acridin carboxylate A compound selected from those of formula (I): ##STR1## wherein: X and Y represent hydrogen, halogen, hydroxy, mercapto, cyano, nitro, alkyl, alkoxy, trihaloalkyl, optionally substituted amino, methylenedioxy, or ethylenedioxy, R1 represents hy... | 01/07/2003 |
| 6379591 | Naphthopyrans annelated in C5-C6 with a lactam-type C6 ring and compositions and (co)polymer matrices containing them The invention relates to novel naphthopyran-type compounds having a lactam-type 6-membered ring annelated in position C5 -C6. These compounds have the formula (I) given below: ##STR1## These compounds (I) have interesting photochromi... | 04/30/2002 |
| 6365594 | Heterocycle-condensed morphinoid derivatives (II) Heterocycle-condensed morphinoid derivatives of formula (I), or solvates or salts thereof, ##STR1## are potent and selective delta opioid agonists and antagonists and are useful as i.a. analgesics. Pharmaceutical compositions containing such compound... | 04/02/2002 |
| 6288073 | Acronycine derivatives, preparation method and pharmaceutical compositions A compound selected from those of formula (I): ##STR1## in which: X and Y represent hydrogen, halogen, hydroxy, mercapto, cyano, nitro, alkyl, alkoxy, trihaloalkyl, optionally substituted amino, methylenedioxy, or ethylenedioxy, R1 represents h... | 09/11/2001 |
| 6277536 | Heterocyclic compounds Compounds of the formula (I) ##STR1## in which the substituents are as defined in claim 1 are valuable colorants for the mass coloring of polymers, with fluorescence property, in electrophotographics toners and developers, in powders coating materials ... | 08/21/2001 |
| 6207084 | Naphthopyrans annelated in C6-C7, their preparation and compositions and (CO)polymer matrices containing them The present invention relates to novel naphthopyrans having a cyclic group annelated in position 6,7. These naphthopyrans have formula (I) given below: ##STR1## These compounds (I) have advantageous photochromic properties. The invention also covers ... | 03/27/2001 |
| 6177567 | Method for preparing oxycodone A method for the preparation of oxycodone, and salts thereof, from codeine comprising oxidation of codeine to codeinone, formation of an dienolsilyl ether congener of codeinone in strong amine base, oxidation of the dienolsilyl ether congener using perace... | 01/23/2001 |
| 6156236 | Conductive organopolysiloxane composition A conductive organopolysiloxane composition is provided which includes (A) 100 parts by weight of an organopolysiloxane; and (B) 0.1 to 800 parts by weight of a conductive material obtained by subjecting a member selected from the group consisting of a co... | 12/05/2000 |
| 6020341 | Enediyne quinone imines and methods of preparation and use thereof A quinone imine enediyne possessing cytotoxic activity towards cancer cells having general structure (I) wherein R1, R2 and R3 are independently the same or different and are H, Br, Cl, F, NH2, CO2 H,... | 02/01/2000 |
| 6013802 | Fluorescent conjugates of metal-chelating nitrogen heterocycles The present invention describes a family of fluorescent indicators for metal cations. The indicators are fluorophore conjugates of pyridyl-based metal ion chelators. The indicators are very sensitive detection as quantification reagents for a variety of m... | 01/11/2000 |
| 5861411 | 4-Acylaminopyridine derivative A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and... | 01/19/1999 |
| 5723625 | Process for the production of specific isomer mixtures from oxindole alkaloids To produce defined isomer mixtures of compounds with spirocyclic beta-aminocarboxyl and/or beta-aminocarbonyl systems the invention supposes that they be dissolved in solvents which have good dissolving power for these compounds, whose relative permittivi... | 03/03/1998 |
| 5536728 | 4-acylaminopyridine derivative A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and... | 07/16/1996 |
| 5530139 | Condensed heterocyclic compound with a sulfonic acid group and process for producing the same A condensed heterocyclic compound having a structure represented by formula (I): ##STR1## wherein the substituents are as defined in the specification herein.... | 06/25/1996 |
| 5527805 | Dynemicin analogs: syntheses, methods of preparation and use A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growth-inhibiting prope... | 06/18/1996 |
| 5416089 | Polycyclic and heterocyclic chromophores for bis-imide tumoricidals Anticancer compounds of formula I: ##STR1## and pharmaceutically acceptable salts thereof, wherein: R1, R2 and R3 are independently selected H, CH3, NH2, NO2, and CN; R9 and... | 05/16/1995 |
| 5397785 | 4-acylaminopyridine derivative A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and... | 03/14/1995 |
| 5276053 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 01/04/1994 |
| 5227487 | Certain tricyclic and pentacyclic-hetero nitrogen rhodol dyes Novel fluorescent dyes based on the rhodol structure are provided. The new reagents contain functional groups capable of forming a stable fluorescent product with functional groups typically found in biomolecules or polymers including amines, phenols, thi... | 07/13/1993 |
| 5071853 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 12/10/1991 |
| 4766055 | Photopolymerizable composition containing a certain xanthene or thioxanthene dyestuff Disclosed is a photopolymerizable composition which is very sensitive to visible light. The composition comprises a polymerizable compound and a photopolymerization initiator wherein the photopolymerization initiator comprises (a) a particular xanthene or... | 08/23/1988 |
| 4547579 | Substituted benzopyran compounds There are described novel dyes of the formulae ##STR1## in which R1 and R2 independently of one another are each hydrogen, unsubstituted or substituted alkyl, cycloalkyl, aralkyl or aryl, and R1 and R2 toge... | 10/15/1985 |
| 4242139 | Water soluble benzoxanthene dyestuffs for fluorescent inks Water-soluble dyestuffs of the formula ##STR1## in which Y is oxygen or an imino group, R1 and R2 are hydrogen, halogen or lower alkyl or lower alkoxy, n is 1 to 3 and Z is a cation, are useful for fluorescent inks.... | 12/30/1980 |
