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| Number | Title | Issue Date |
| 7439366 | Phenacylamine derivatives, process for their production and pesticides containing them The present invention relates to a phenacylamine derivative of the formula (I) or a salt thereof: wherein A is alkyl, cycloalkyl, phenyl which may be substituted by Y, pyridyl which may be substituted by Y, or pyrazolyl whi... | 10/21/2008 |
| 7189383 | Radioactively labelled amino acid analogues, their preparation and use The present invention relates to Halogenated amino acid analogues for use in diagnosis, which compounds have the general formula (I) wherein: R is (C1–C6) alkyl optionally substituted with thioether or ether oxygen atom when n=0, or a substit... | 03/13/2007 |
| 7002018 | Process for the preparation of amorphous form of torsemide The present invention relates to a simple and efficient process for the preparation of amorphous form of torsemide. The process includes recovering amorphous torsemide from a solution thereof in a suitable solvent comprising alcohols, ketones, chlorinated hydrocarbo... | 02/21/2006 |
| 6943258 | Polymer compounds containing oxetane and cinnamyl functionality These compounds contain an oxetane functionality and a cinnamyl functionality. The oxetane functionality is homopolymerizable in reactions that can undergo cationic or anionic ring opening, and the cinnamyl functionality is polymerizable with compounds such as elect... | 09/13/2005 |
| 6919460 | Processes and intermediates useful in preparing β3-adrenergic receptor agonists The present invention provides processes useful in the preparation of certain β3-adrenergic receptor agonists of the structural formula the pharmaceutically acceptable salts thereof, and the hydrates of sai... | 07/19/2005 |
| 6855850 | Method of manufacturing fluorine compounds, and a method of recovering or regenerating precursors of fluorinating agents To provide a practical method of manufacturing fluorine compounds in a small number of steps that can carry out fluorination reaction of substrates using easily available fluorinating agents that can be inexpensively produced industrially, and recover precursors of ... | 02/15/2005 |
| 6844441 | Process for preparing substituted pyridines A process for preparing a compound of the formula: wherein n, R1, R2, R3 and X are as defined above, used as an intermediate in the synthesis of β-adrenergic receptor agonists. ... | 01/18/2005 |
| 6770463 | Process for the preparation of chiral isofluoroenes There is provided a process for the preparation of a chiral insecticidal and acaricidal compound of formula I. Also provided are intermediate compounds useful in the process of the present invention. ... | 08/03/2004 |
| 6699853 | 4-HALOALKYL-3-HETEROCYCLYLPYRIDINES, 4-HALOALKYL-5-HETEROCYCLYL-PYRIMIDINES AND 4-TRIFLUOROMETHYL-3-OXADIAZOLYLPYRIDINES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PESTICIDES The present invention relates to 4-Haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, Processes for Their Preparation, Compositions Comprising Them, and Their Use as Pesticides More part... | 03/02/2004 |
| 6667401 | Method for producing heterocyclic compounds The present invention relates to a process for the preparation of compounds of the formula (I) ##STR1## in which R1, A, D, X and Z have the meanings given in the description, by reacting compounds of the formula (II) ##STR2## in wh... | 12/23/2003 |
| 6656957 | Pyridine derivatives A compound of formula I ##STR1## wherein X represents an optionally halo-substituted (C2-4)alkynylene group bonded via vicinal unsaturated carbon atoms.... | 12/02/2003 |
| 6491989 | Fluorinated naphthalene derivatives and their use in liquid crystal mixtures Fluorinated naphthalene derivatives of the formula (I) R1 (--A1 --M1)a (--A2 --M2)b --B--(--M3 --A3)c --(M4 --A4)d --R | 12/10/2002 |
| 6489334 | Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms The invention relates to a method of crystallizing a tetrahydropyridine derivative, to the novel crystalline forms thereby obtained and to the pharmaceutical compositions containing said tetrahydropyridine derivative in a given crystalline form as the act... | 12/03/2002 |
| 6485797 | 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same A ferroelectric liquid crystal mixture, especially useful for operation in the ͌Vmin -mode, comprises a 5-Arylindane derivative of the formula (I), ##STR1## wherein Y is CH, CF or N and R1 (--A1 --M1)a | 11/26/2002 |
| 6417361 | Fluorination agent and preparation and use of same The invention disclose a hydrogen fluoride containing composition comprising hydrogen fluoride and a compound which is liquid in the standard state (25° C., 1 atmosphere) and has a boiling point of 120° C. or more and pka of 12 or more at 25° C., and u... | 07/09/2002 |
| 6392050 | Process for preparing substituted pyridines The invention relates to a process for preparing substituted pyridines in a simple and cost-effective manner in good yields by reacting substituted 1,4-dihydropyridines with methyl nitrite in the presence of an acid that contains less than 20% by weight o... | 05/21/2002 |
| 6309561 | Liquid crystal compounds having a chiral fluorinated terminal portion Fluorine-containing, chiral liquid crystal compounds comprise (a) a chiral fluorochemical terminal portion comprising (i) at least one chiral center, which can optionally be heteroatom-substituted; (ii) a terminal fluoroalkyl, fluoroether, perfluoroalkyl,... | 10/30/2001 |
| 6268503 | 2-phenylpyridine derivative and production method thereof A series of compounds capable of deriving an intermediate for the production of compound (A) of the following formula, ##STR1## which is an anti-HIV drug, and a production method thereof. To be specific, 4-(pyridin-2-yl)benzaldehyde hydrazone, a productio... | 07/31/2001 |
| 6184384 | Dechlorination of pyridines in acidic, zinc-containing mediums Described are preferred processes for preparing 3,5-dichloropyridines by dechlorinating higher-chlorinated pyridine compounds such as 2,3,5,6-tetrachloropyridine in an acidic medium in the presence of zinc and optionally a quaternary ammonium catalyst.... | 02/06/2001 |
| 6184425 | Process for preparing fluorine-containing compounds The present invention relates to a process for preparing fluorine-containing compounds by reacting a compound which contains fluorine-exchangeable halogen with a fluoride or a mixture of fluorides with the formula I MeF (I), in which Me is an alkaline ea... | 02/06/2001 |
| 6162810 | Inadone and tetralone compounds for inhibiting cell proliferation A new family of inadone and tetralone tubulin-binding compounds (TBs) is disclosed. Unlike classical TBs, which inhibit mitosis among affected dividing cells, the TBs of the invention possess two unique properties: (1) they induce apoptosis among stationa... | 12/19/2000 |
| 6147082 | Chalcones having antiproliferative activity The invention relates to a novel class of compounds that have structures related to certain naturally occurring or synthetic chalcones. The invention also relates to pharmaceutical compositions comprising the compounds and methods for treating certain dis... | 11/14/2000 |
| 6118006 | Method for preparing a tetrahydropyridin derivative The invention relates to a method for the preparation of 1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyri dine and its pharmaceutically acceptable salts by reacting 2-(2-bromoethyl)naphthalene with 4-(3-trifluoromethylphenyl)... | 09/12/2000 |
| 6066766 | Process for the preparation of 4-chlorobiphenyls 4-Chlorobiphenyls are prepared by reacting a haloaromatic with an aryl Grignard compound, where halogen is chlorine, bromine or iodine, in the presence of a palladium catalyst of the formula (IV) ##STR1##... | 05/23/2000 |
| 6051288 | Fluorine-substituted liquid-crystal compound, liquid-crystal composition and liquid-crystal display device An object of the present invention is to provide a novel liquid crystalline compound having a large dielectric anisotropy, small change in threshold voltage depending on temperature, and an improved solubility to other liquid crystal materials at low temp... | 04/18/2000 |
| 6034090 | 1-Phenylalkyl-1,2,3,6-tetrahydropyridines for treating Alzheimer's disease The invention relates to compounds of the formula in which: Y is --CH-- or --N--; R1 is hydrogen, a halogen or a CF3, (C1 -C4)alkyl or (C1 -C4)alkoxy group; R2 is a methyl or eth... | 03/07/2000 |
| 6022492 | Difluorophenyl pyrimidyl pyridine derivatives and the use thereof in liquid crystal mixtures Difluorophenylpyrimidylpyridine derivatives of the formula (I) ##STR1## wherein X is N and Y is CH or X is CH and Y is N; R1 and R2 are identical or different and are a) an unbranched or branched alkyl chain having 1 to 20 carbon atoms, w... | 02/08/2000 |
| 6010980 | Substituted 2-phenylpyridines as herbicides Substituted 2-phenylpyridines I and their salts ##STR1## where n=0, 1; R1 =halogen, C1 -C4 -haloalkyl; R2 and R3 =H, halogen; R4 =CN, halogen; R5 =--CO--O-(C1 -C4 | 01/04/2000 |
| 5990314 | Pharmaceutical pyridine compounds This invention relates to a compound of formula I ##STR1## These compounds are leukotriene antagonists and as such can be used in treating various diseases associated with leukotrienes.... | 11/23/1999 |
| 5972241 | Liquid crystal compounds having a chiral fluorinated terminal portion Fluorine-containing, chiral liquid crystal compounds comprise (a) a chiral fluorochemical terminal portion containing at least one methylene group and optionally containing at least one catenary ether oxygen atom; (b) a saturated, chiral or achiral, hydro... | 10/26/1999 |
| 5961958 | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth The present invention discloses compositions containing a transfer agent and/or bactericidal compounds, and hydrophobic materials which form, upon application to dental surfaces, adhesive, protective and bacteria-inhibiting barriers.... | 10/05/1999 |
| 5942625 | Preparation of chloromethylpyridine hydrochlorides Chloromethylpyridine hydrochlorides such as 3-chloromethylpyridine hydrochloride, an important pharmaceutical intermediate, are prepared in high yield and high purity by reacting the corresponding pyridyl carbinol with a slight excess of thionyl chloride,... | 08/24/1999 |
| 5925645 | 2-aryl-substituted pyridines The 2-aryl-substituted pyridines are prepared by reacting pyridylaldehydes with organometallic compounds and then selectively reducing the products. The 2-aryl-substituted pyridines are suitable as active compounds in medicaments, in particular in medicam... | 07/20/1999 |
| 5922880 | Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production The dihalopropene compounds of the general formula I! have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks.... | 07/13/1999 |
| 5886186 | Synthesis of substituted N-heteroaromatic compounds and methods of use thereof The subject invention features substituted N-heteroaromatic compounds, libraries of substituted N-heteroaromatic compounds, and methods of synthesis thereof. For example, the present invention provides methods for synthesizing substituted N-heteroaromatic... | 03/23/1999 |
| 5869506 | Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof The present invention provides a fluoropropene compound represented by Formula I: ##STR1## wherein R1 represents a C1 -C10 alkyl group or other groups, Z represents an oxygen atom or other groups, R2, R | 02/09/1999 |
| 5861109 | Liquid crystal materials, mixtures and devices Liquid crystal compounds of formula I may be used by themselves or they may be mixed with other liquid crystal compounds to give useful liquid crystal mixtures which may then be used in liquid crystal devices. The materials exhibit smectic mesophases and ... | 01/19/1999 |
| 5856286 | Surfactants for use in drying and dry cleaning compositions The invention provides a fluorinated surfactant for use with halocarbon and hydrofluoroether solvents. Additionally, the invention provides drying, dry cleaning, and soil repellency compositions containing a halocarbon or hydrofluoroether and a fluorinate... | 01/05/1999 |
| 5852189 | Tertiaryaminoalkyllithium initiators and the preparation thereof Relatively pure tertiaryaminoalkyllithium initiators suitable for anionic polymerization reactions are prepared at low temperatures in an organic ether by reacting an equivalent excess of lithium metal with a tertiaryaminoalkylhalide. The lithium initiato... | 12/22/1998 |
| 5756497 | Tocolytic oxytocin receptor antagonists This invention relates to certain novel benzoxazinone compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans... | 05/26/1998 |
