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| Number | Title | Issue Date |
| 7678920 | Insecticidal -substituted sulfoximines N-Substituted sulfoximines are effective at controlling insects. ... | 03/16/2010 |
| 7241782 | Polymorph V of torasemide The invention relates to a novel polymorph V of torasemide, to a process for its preparation, to its use as a raw material for the preparation of crystalline modifications I and III of torasemide, to amorphous torasemide modifications and to pharmaceutically accepta... | 07/10/2007 |
| 7105549 | Aryl substituted pyridines and the use thereof This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1–R4 are set in the specification. The in... | 09/12/2006 |
| 6936597 | Prodrugs of anticancer agents employing substituted aromatic acids Polymeric prodrugs of the formula: wherein B is selected from the group consisting of OH, leaving groups, residues of amine-containing moieties and a residues of hydroxyl-containing m... | 08/30/2005 |
| 6930130 | Citrullimycines, a process for their production and their use as pharmaceuticals The present invention relates to novel active compounds named Citrullimycines, which are obtainable by cultivation of Streptomyces sp. ST 101396 (DSM 13309), and to their pharmaceutically acceptable salts and derivatives. The present invention further relates... | 08/16/2005 |
| 6852863 | Metabolites of (3-{[4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid The present invention relates to metabolites of (3-{[4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid. ... | 02/08/2005 |
| 6825221 | Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain According to the invention there is provided a compound the formula I; wherein A, X, B, R1, R2, R3 and R4 are as defined in the specification. ... | 11/30/2004 |
| 6747041 | Heterocyclic dicarboxylic acid diamide derivatives, agricultural/horticultural insecticides and method of using the same Heterocyclic dicarboxylic acid diamide derivative represented by the general formula (I): wherein R1, R2 and R3 represent each H, optionally halogenated C3-6 cycloalkyl, etc.; ... | 06/08/2004 |
| 6521626 | Thiocarboxamide derivatives Compounds of formula (1): ##STR1## wherein R1 is a hydrogen atom or an optionally substituted cycloaliphatic, polycycloaliphatic, heterocycloaliphatic, polyheterocycloaliphatic, aromatic or heteroaromatic group; Alk1 is an optionally... | 02/18/2003 |
| 6511993 | Metalloprotease inhibitors ##STR1## Compounds of formula (I) and pharmaceutically-acceptable derivatives thereof, are matrix metalloprotease inhibitors, useful in treatment of conditions mediated by matrix metalloproteases, such as chronic dermal ulcers.... | 01/28/2003 |
| 6465471 | Cinnamic acid derivatives Compounds of formula (1) are described: ##STR1## in which Het is a heteroaromatic group, Alk1 is an optionally substituted aliphatic or heteroaliphatic chain and R is a carboxylic acid or a derivative thereof. The compounds are able to inhibit ... | 10/15/2002 |
| 6339045 | N-(unsubstituted or substituted)-4-substituted-6-(unsubstituted or substituted)phenoxy-2-pyridinecarboxamides or thiocarboxamides, processes for producing the same, and herbicides N-(substituted or unsubstituted)-4-substituted-6-(substituted or unsubstituted) phenoxy-2-pyridine carboxamide or thiocarboxamide represented by the general formula (I) and a process for producing the compound. A herbicide containing as an effective ingre... | 01/15/2002 |
| 6214835 | Dihalopropene compounds insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are independentl... | 04/10/2001 |
| 6191280 | Method for producing substituted thiopyridines A process for preparing thiopyridines of the formula I ##STR1## where the substituents are as defined in the description.... | 02/20/2001 |
| 6121273 | N-linked sulfonamides of heterocyclic thioesters This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin pr... | 09/19/2000 |
| 6110945 | Aromatic amine derivatives Aromatic amines of formula (1) are described: ##STR1## wherein Az is an optionally substituted monocyclic six-membered nitrogen-containing aromatic group; L1 is a linker atom or group; R is a carboxylic acid or a derivative thereof; and R5... | 08/29/2000 |
| 6005112 | Process for producing pyridinecarboxamides or thiocarboxamides A process for producing N-substituted pyridine carboxamide or thiocarboxamide, comprising reacting a substituted or unsubstituted pyridine metal compound with substituted isocyanate or isothiocyanate to obtain an addition reaction product thereof, and the... | 12/21/1999 |
| 5919792 | Integrin antagonists This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are v댣 antagonists, ... | 07/06/1999 |
| 5834467 | HIV protease inhibitors HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain the... | 11/10/1998 |
| 5705513 | Fungicides for the control of take-all disease of plants A compound, composition, and method for controlling Take-all disease of plants by applying to the seed prior to planting, a fungicide of the formula: ##STR1## wherein Z1 and Z2 are C and are part of an aromatic ring which i... | 01/06/1998 |
| 5597839 | Di(aromatic) compounds and their use in human and veterinary medicine and in cosmetics Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## X represents a divalent radical, Z represents O, S or a divalent radical, and R1, R2, R3, R4 a... | 01/28/1997 |
| 5571897 | Luminescent lanthanide chelates Lanthanide chelates which contain three heterocyclic rings covalently coupled to each other (either one 2,6-pyridylene and two five-membered unsaturated heterocyclic ring moieties or two 2,6-pyridylene and one five-membered unsaturated heterocyclic ring m... | 11/05/1996 |
| 5439925 | Di(aromatic) compounds and their use in human and veterinary medicine and in cosmetics Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## n=1 or 2 or: ##STR3## X represents a divalent radical, Z represents O, S or a divalent radical, and R1, R2 | 08/08/1995 |
| 5389653 | Catechol derivatives Catechol derivatives of the formula ##STR1## wherein Ra, Rb and Rc have the significance given herein, the ester and ether derivatives thereof which are hydrolyzable under physiological conditions and the pharmaceutically acceptable salts thereof are... | 02/14/1995 |
| 5225545 | Disazo dyes containing a 1-hydroxy-3-sulfo-acylaminophenyl-amino-naphthalene coupling component The compounds of the formula (1) indicated in claim 1 are suitable for use as direct dyes for dyeing and printing a wide range of materials, in particular cellulose-containing fibre materials, producing dyeings and prints having good fastness properties.... | 07/06/1993 |
| 5169432 | Substituted 2,6-substituted pyridine herbicides Substituted pyridines having at the 3 or 5 position a carbonyl oxy(thio)ester or a heterocyclocarbonyl and at the other a substituted alkyl group, herbicidal compositions and methods of use thereof.... | 12/08/1992 |
| 5142057 | Process for producing carboxylic acid amides A process for producing a carboxylic acid amide or ester, which comprises reacting an organic chloride having at least one chlorine atom on its ring of a substituted or unsubstituted, aromatic or heterocyclic hydrocarbon with carbon monoxide and an amine ... | 08/25/1992 |
| 5129943 | Substituted pyridine compounds Disclosed herein are 2- or 6-fluoromethyl-3-pyridinecarboxylate derivatives with 5-[(heterocyclic)ylidene]amino substitution useful as herbicides and herbicide intermediates.... | 07/14/1992 |
| 5099023 | Process for preparation of fluoromethyl-substituted pyridine carbodithioates A process for dehydrofluorination of a 2,6-(bis) trifluoromethyl-dihydropyridine-3,5-dicarbothioic acid ester.... | 03/24/1992 |
| 5099024 | Process for preparation of fluoromethyl-substituted pyridine carbodithioates A process for dehydrofluorination of a 2,6-(bis)trifluoromethyl-dihydropyridine-3,5-dicarbothioic acid ester.... | 03/24/1992 |
| 5008276 | Methyl -(2-substituted)pyrid-3-yl-ଲ-methoxyacrylates, compositions containing them and their use as fungicides Fungicidal compounds of the formula (I): ##STR1## and stereoisomers thereof, wherein K is oxygen or sulphur; Z is optionally substituted aryl or optionally substituted heteroaryl; X is O, S(O)n, NR4, CR1 R2... | 04/16/1991 |
| 4973429 | Organic materials with non-linear optical properties A material in the form of a film is described which contains, in an orientated arrangement which does not display point symmetry, compounds of formula I ##STR1## wherein X is .dbd.CH-- or .dbd.N--, R1 is C12 -C30 -alk... | 11/27/1990 |
| 4950762 | 2-pyridinecarbothioamides, processes for preparation thereof There are provided gastric antiulcer and cytoprotective substituted N-phenyl-2-pyridinecarbothioamides. The process for their production and formulation is disclosed.... | 08/21/1990 |
| 4886821 | 2-pyridinecarbothioamides and pharmaceutical compositions comprising the same useful as anti ulcer agents There are provided gastric antiulcer and cytoprotective substituted N-phenyl-2-pyridinecarbothioamides. The process for their production and formulation is disclosed.... | 12/12/1989 |
| 4873238 | 2-Pyridinecarbothioamides and pharmaceutical compositions comprising the same There are provided gastric antiulcer and cytoprotective substituted N-phenyl-2-pyridinecarbothioamides. The process for their production and formulation is disclosed.... | 10/10/1989 |
| 4835279 | 2,6-substituted pyridine compounds Disclosed herein are 3,5-pyridinedicarboxylic acid derivatives having halogen substitution at the 4 position which are useful as herbicides and herbicide precursors.... | 05/30/1989 |
| 4782074 | Fungicidal N,N-disubstituted-heterocyclic carboxamides The substituted heteroaryl compounds of this invention are good fungicides. In particular, they possess especially good activity against Bean Powdery Mildew.... | 11/01/1988 |
| 4692184 | 2,6-substituted pyridine compounds There are disclosed novel 2,6-substituted-3,5-pyridinedicarboxylic acids, esters, salts, amides, halides, and cyano compounds useful as herbicides, and as intermediates which provide herbicides.... | 09/08/1987 |
| 4654346 | Fungicidal N,N-disubstituted-heterocyclic carboxamides The substituted heteroaryl compounds of this invention are good fungicides. In particular, they possess especially good activity against Bean Powdery Mildew.... | 03/31/1987 |
| 4613356 | Aryloxyphenoxy propionylthioureas which are useful as herbicides Substituted aryloxyphenoxy propionyl thiourea compounds useful as herbicides, and their methods of use, a representative one of which has the structural formula ##STR1## The method comprises applying the above referenced compound to the locus wh... | 09/23/1986 |
