Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8399680 | Arylamine synthesis method The invention relates to a method for preparing arylamines and, in particular, a method for preparing aniline and anilines substituted on the aromatic ring from ammonia, under easily-industrialized mild conditions with good selectivity and yields, in the presence of... | 03/19/2013 |
| 8063226 | Process for preparing 2-amino-4-(haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds A process in which a 2-aminopyridine derivative of the general formula II is obtained from open-chain nitrile precursor I or III by reaction with a nitrogen compound in a cyclization reaction is described. ... | 11/22/2011 |
| 7435743 | Pyridine derivatives Pyrimidine compounds of general formula: wherein —R1 represents in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy,... | 10/14/2008 |
| 7432227 | 6-alkyl or alkenyl-4-aminopicolinates and their use as herbicides 4-Aminopicolinic acids having alkyl or alkenyl substituents in the 6-position and their amine and acid derivatives are potent herbicides demonstrating a broad spectrum of weed control. ... | 10/07/2008 |
| 7342115 | 3-substituted-6-aryl pyridines 3-substituted-6-aryl pyridines of Formula I are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptor. Preferred... | 03/11/2008 |
| 7320985 | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid A method for stabilizing an arylcarboxylic acid, which comprises adding a heterocyclic base to the arylcarboxylic acid or a pharmacologically acceptable salt thereof, a stabilizer thereof and an aqueous solution containing a stabilized arylcarboxylic acid. According... | 01/22/2008 |
| 7220863 | Process for preparing 2-aminopyridine derivatives A method for preparing 2-aminopyridine derivatives, which comprises substituting of fluorine for hydrazine moiety and reducing with hydrogen using 3-substituted-2,5,6-trifluoropyridine as a starting material, provides 2-aminopyridine derivatives having a purity over... | 05/22/2007 |
| 7148229 | Sulfonamide substituted xanthine derivatives The present invention is a sulfonamide substituted xanthine derivative of formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is lower alkyl, lower alkyl substituted by phenyl, or lower alkyl sub... | 12/12/2006 |
| 7129238 | Mandelic acid derivatives The invention is concerned with novel mandelic acid derivatives of formula (I) wherein R1 to R10, X and Y are as defined in the description and in the claims, as well as pharmaceutically acc... | 10/31/2006 |
| 7067541 | 2-amino-pyridine derivatives useful for the treatment of diseases The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds accord... | 06/27/2006 |
| 7056909 | Alpha v integrin receptor antagonists The present invention relates to novel chain-fluorinated alkanoic acid derivatives thereof, their synthesis, and their use as αv integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors αvβ... | 06/06/2006 |
| 7034044 | Conjugated aromatic compounds with a pyridine substituent The present invention relates to compounds of formulae The compounds of the present invention are NMDA (N-methyl-D-aspartate)-receptor subtype blockers and are used in the treatment of diseases related to this receptor. | 04/25/2006 |
| 7022718 | Pyridine and pyrimidine derivatives The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The co... | 04/04/2006 |
| 7012078 | 2-aminopyridines containing fused ring substituents The present invention relates to 2-aminopyridine derivatives of the formula wherein G, R1 and R2 are defined as in the specification, that exhibit activity as nitric oxide synthase (NOS) inhibitor... | 03/14/2006 |
| 6984649 | Pyridine derivatives Pyridine compounds of general formula: wherein —R1 represents in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 ... | 01/10/2006 |
| 6951875 | Conjugated aromatic compounds with a pyridine substituent The present invention relates to compounds of formulae The compounds of the present invention are NMDA (N-methyl-D-aspartate)-receptor subtype blockers and are used in the treatment of diseases related to this receptor... | 10/04/2005 |
| 6803470 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines The present invention relates to the compounds 6-[4-(N-methyl-3-azetidinoxy)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine, 6-[4-(N,N-dimethylaminomethyl)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine, 6-[4-(N-methylaminomethyl)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylami... | 10/12/2004 |
| 6800650 | Pyridine and quinoline derivatives The present invention provides compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compou... | 10/05/2004 |
| 6800784 | Process for preparing a polyaromatic compound The present invention concerns a process for preparing a polyaromatic compound comprising a concatenation of two aromatic cycles and carrying at least one amino group on one of the aromatic cycles. The process of the invention is characterized in that it consists of... | 10/05/2004 |
| 6589967 | Oxime O-ether compounds and fungicides for agricultural and horticultural use The present invention relates to novel oxime O-ether compounds represented by a general formula [I]; ##STR1## wherein R1 represents C1-6 alkyl, C3-6 cycloalkyl, C1-6 alkoxy, etc., m represents an integer of 1 to... | 07/08/2003 |
| 6492515 | 4,4-disubstituted-1, 4-dihydro-2H-3, 1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same The present invention relates to benzoxazinones of formula I: ##STR1## or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions ... | 12/10/2002 |
| 6465491 | 6-phenylpyridyl-2-amine derivatives The present invention relates to certain 6-phenyl-pyridin-2-ylamine derivatives that exhibit activity as nitric oxide synthase (NOS) inhibitors, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central ner... | 10/15/2002 |
| 6433214 | Process for the preparation of 2-(4-methylphenyl)-benzoic acid derivatives A process for the preparation of 2-(4-methylphenyl)benzoic acid C1-6 alkyl esters by reaction of a sulfonic derivative of formula ##STR1## wherein R is C1-6 alkyl and R1 is optionally perfluorinated C1-6 alkyl o... | 08/13/2002 |
| 6410737 | Processes for preparing pesticidal intermediates Compounds of formula (I) are prepared by hydrogenolysis of a compound of formula (II): ##STR1## where R1 is haloalkyl, haloalkoxy or -SF5 ; W is N or CR3 ; and R2 and R3 are H or Cl. The compounds of ... | 06/25/2002 |
| 6399781 | Process for making 3-amino-2-chloro-4-methylpyridine A method for making 3-amino-2-chloro-4-methylpyridine, as shown in Scheme 12, below. ##STR1##... | 06/04/2002 |
| 6372768 | 2-aminopyridines containing fused ring substituents The present invention relates to 2-aminopyridine derivatives of the formula I: ##STR1## or pharmaceutically acceptable salts thereof, wherein A and B are each independently H, or together, A and B form a ring fused to the phenyl ring, said ring being satu... | 04/16/2002 |
| 6323366 | Arylamine synthesis The present invention provides a method for the preparation of a wide range of primary arylamines. The arylamines are prepared in two efficient, straightforward transformations: 1) an activated aryl group and an imine group are combined, in the presence o... | 11/27/2001 |
| 6297197 | 4-aminopicolinates and their use as herbicides 4-Aminopicolinic acids, having halogen, alkoxy, alkylthio, aryloxy, heteroaryloxy or trifluoromethyl substituents in the 3-, 5- and 6-positions, and their amine and acid derivatives are potent herbicides demonstrating a broad spectrum of weed control.... | 10/02/2001 |
| 6211208 | 2-aminopyridines containing fused ring substituents The present invention relates to 2-aminopyridine derivatives of the formula I: ##STR1## or pharmaceutically acceptable salts thereof, wherein A and B are each independently H, or together, A and B form a ring fused to the phenyl ring, said ring being satu... | 04/03/2001 |
| 6194599 | Process for preparing biaryl compounds The present invention provides a process for preparing biaryl compounds comprising reacting an arylzinc reagent with an arylchloride in the presence of a nickel catalyst or a palladium catalyst. The present invention specifically provides a process for th... | 02/27/2001 |
| 6156903 | Pyridonecarboxylic acid derivatives or their salts, and antibacterial agents containing the same as their effective components A pyridonecarboxylic acid derivative represented by the following general formula (1): ##STR1## [wherein R1 represents hydrogen atom or a carboxyl protective group; R2 represents hydroxyl group, a lower alkoxy group, or a substi... | 12/05/2000 |
| 6124457 | Process and intermediates for a ଲ3 -adrenergic receptor agonist The instant invention relates to intermediates of Formula II, ##STR1## wherein R1, R2 and R3 are as defined in the specification, and to processes for preparing such intermediates. This invention also relates to proce... | 09/26/2000 |
| 6034241 | Process for converting hydroxy heteroaromatics to arylamines A process of converting a hydroxy heteroaromatic compound to an arylamine, comprising the steps of: (1) treating a salt of a hydroxy heteroaromatic compound with an alkylating agent; and (2) treating the reaction mixture with a Smiles solvent system and raisin... | 03/07/2000 |
| 6001856 | ଲ-adrenergic agonists to reduce a wasting condition The present invention relates to the use of certain ଲ-adrenergic agonists to reduce a wasting condition in a mammal (e.g., human).... | 12/14/1999 |
| 5972975 | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders. ##STR1##... | 10/26/1999 |
| 5969140 | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor Naphthalene derivatives of the formula [I]: ##STR1## wherein R1 and R2 are the same or different and are each H, protected or unprotected OH, one of R3 and R4 is protected or unprotected hydroxymethyl, and ... | 10/19/1999 |
| 5959116 | Pyridine-2, 3-dicarboximides their preparation and their use for controlling undesired plant growth A pyridine-2,3-dicarboxylic acid diester of the formula Va ##STR1## where the radicals R2 and R4 have the meanings set out in the specification and where R8 is a C1 -C4 -alkyl, C3 -C | 09/28/1999 |
| 5922898 | Process for preparing biaryl compounds The present invention provides a process for preparing biaryl compounds comprising reacting an arylmetal reagent selected from arylmagnesium reagents and aryllithium reagents with an arylhalide in the presence of a catalyst system comprising a catalyst se... | 07/13/1999 |
| 5919792 | Integrin antagonists This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are v댣 antagonists, ... | 07/06/1999 |
| 5886186 | Synthesis of substituted N-heteroaromatic compounds and methods of use thereof The subject invention features substituted N-heteroaromatic compounds, libraries of substituted N-heteroaromatic compounds, and methods of synthesis thereof. For example, the present invention provides methods for synthesizing substituted N-heteroaromatic... | 03/23/1999 |
