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| Number | Title | Issue Date |
| 8115007 | Synthesis of diaminodinitropyridine A process for the preparation of diaminodinitropyridine or diaminodinitrobenzene by contacting an aminopyridine or aminobenzene with oleum and nitric acid, wherein the improvement comprises adding at least about 1% molar excess of nitric acid, based upon the aminopy... | 02/14/2012 |
| 7687633 | Filters for electronic display devices The present invention provides a filter for electronic display devices, comprising a squarylium compound represented by General Formula (I): [wherein X represents a group represented by following Formula (A): | 03/30/2010 |
| 7449584 | N-(2((4-Hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide Crystalline Form 1 N-(2-((4-Hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide Crystalline Form 1, ways to make it, compositions containing it and methods of treatment of diseases using it are disclosed. ... | 11/11/2008 |
| 7446206 | N-((2Z)-2-((4-hydroxyphenyl) amino)-1,2-dihydro-3-pyridinyl)-4-methoxybenzenesulfonamide crystalline form 2 N-((2Z)-2-((4-Hydroxyphenyl)imino)-1,2-dihydro-3-pyridinyl)-4-methoxybenzenesulfonamide Crystalline Form 2, ways to make it, compositions containing it and methods of treatment of diseases using it are disclosed. ... | 11/04/2008 |
| 7435743 | Pyridine derivatives Pyrimidine compounds of general formula: wherein —R1 represents in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy,... | 10/14/2008 |
| 7342115 | 3-substituted-6-aryl pyridines 3-substituted-6-aryl pyridines of Formula I are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptor. Preferred... | 03/11/2008 |
| 7317112 | Catalysts for selective isocyanate dimerization A method of dimerizing isocyanates using sulphonamide anions as a dimerization catalyst for the isocyanates and also to a process for preparing oligomeric isocyanates using such catalysts. ... | 01/08/2008 |
| 7288493 | Body armor with improved knife-stab resistance formed from flexible composites Flexible body armor formed from flexible composites which have improved knife-stab resistance. The body armor is formed from composites which include layers of a fabric base, formed from high tenacity fibers, and a rubber layer bonded to the fabric base. A thermopla... | 10/30/2007 |
| 7226936 | Pyridinic sulfonamide derivatives method of production and use thereof New pyridinic sulfonamide derivatives represented by a general formula (I), wherein R1, represents a mono- or polyhalogenated C1–12-alkyl or a mono- or poly-halogenated C3–8-cycloalkyl group. The method of production of such derivatives and their use as active t... | 06/05/2007 |
| 7223778 | 5-substituted-2-arylpyridines Novel 5-substituted-2-arylpyridine compounds are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyridine compounds provided herein are useful in the treatment of a number of CNS and periphereal disorders, particula... | 05/29/2007 |
| 7223868 | Heteroaromatic glucokinase activators 2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 3-position being a substituted phenyl group and at the 2-position being a methyl cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secretion in the ... | 05/29/2007 |
| 7208507 | Pyridines and uses thereof The invention relates to pyridines and uses thereof, including to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity and/or proliferation of cells such as tumor cells. ... | 04/24/2007 |
| 7176312 | Kinase inhibitor scaffolds and methods for their preparation General methods for the solution phase as well as solid phase synthesis of various substituted heteroaryls has been demonstrated. These substituted heteroaryls can be further elaborated by aromatic substitution with amines at elevated temperature or by anilines, bor... | 02/13/2007 |
| 7138418 | Pentafluorobenzenesulfonamides and analogs The invention provides methods and compositions relating to novel pentafluorophenylsulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states... | 11/21/2006 |
| 7132546 | Aniline derivatives or salts thereof and cytokine production inhibitors containing the same The present invention provides a cytokine production inhibitor containing as an active ingredient an aniline derivative of the formula (I) or a salt thereof: [wherein A is CO or SO2; Cy is an aryl grou... | 11/07/2006 |
| 7132425 | 5-substituted-six-membered heteroaromatic glucokinase activators The present invention provides a compound according to formula I where the substituent designations are provided in the specification. Pharmaceutical compositions comprising a compound according to formula I are ... | 11/07/2006 |
| 7109220 | Amino substituted pyridinyl methanone compounds useful in treating kinase disorders The present invention provides amino substituted pyridinyl methanone compounds; pharmaceutical compositions comprising the compounds and methods of synthesis thereof. The compounds, which are cyclin dependent kinase (CDK) inhibitors, can be used to treat or ameliora... | 09/19/2006 |
| 7052936 | Use of polybenzoxazoles (PBOS) for adhesion The present invention describes the use of polybenzoxazoles (PBOs) for adhesively bonding articles or materials, especially components used in the semiconductor industry, such as chips and wafers, a process for adhesively bonding materials, especially chips and wafe... | 05/30/2006 |
| 7034044 | Conjugated aromatic compounds with a pyridine substituent The present invention relates to compounds of formulae The compounds of the present invention are NMDA (N-methyl-D-aspartate)-receptor subtype blockers and are used in the treatment of diseases related to this receptor. | 04/25/2006 |
| 6989382 | Carbocycle based inhibitors of glycogen synthase kinase 3 New carbocyclic compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alon... | 01/24/2006 |
| 6962929 | Pentafluorobenzenesulfonamides and analogs The invention provides methods and compositions relating to novel pentafluorophenylsulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states... | 11/08/2005 |
| 6953805 | Excitatory amino acid receptor antagonists The present invention provides novel compounds of Formula I or Formula II, or the pharmaceutically acceptable salts or prodrugs thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I or Formula II in combination with a suitabl... | 10/11/2005 |
| 6919460 | Processes and intermediates useful in preparing β3-adrenergic receptor agonists The present invention provides processes useful in the preparation of certain β3-adrenergic receptor agonists of the structural formula the pharmaceutically acceptable salts thereof, and the hydrates of sai... | 07/19/2005 |
| 6911595 | Charge transfer material, and photoelectric conversion device and photoelectric cell using same, and pyridine compound A charge transfer material comprising a basic compound having negative charge and represented by the following general formula (I): (A1-L)n1-A2·M (I), wherein A1 represents a group having negativ... | 06/28/2005 |
| 6903088 | Compounds which inhibit leukocyte adhesion mediated by VLA-4 Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, su... | 06/07/2005 |
| 6833378 | Corticotropin releasing factor antagonists Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined... | 12/21/2004 |
| 6809109 | 2, 4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors The present invention relates to 2,4-disubstituted pyridine-N-oxide compounds of formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhib... | 10/26/2004 |
| 6794377 | Ortho, ortho-substituted nitrogen-containing bisaryl compounds, processes for their preparation, their use as medicaments, and pharmaceutical preparation comprising them Ortho, ortho-substituted nitrogen-containing bisaryl compounds, processes for their preparation, their use as medicaments, and pharmaceutical preparations including their use as antiarrhythmic active compounds, for example, for the treatment and prophylaxis of atria... | 09/21/2004 |
| 6747048 | Pyridine-based thyroid receptor ligands Novel pyridine-based thyroid receptor ligands are provided which have the general formula I wherein: X is oxygen (—O—), sulfur (—S—), sulfoxide (—S(O)—), sulfonyl (—SO2—), CR8... | 06/08/2004 |
| 6699990 | 3-(2,5-diaminophenyl)-acrylamide derivatives and coloring agents containing said compounds The present patent application relates to 3-(2,5-diaminophenyl)acrylamide derivatives of general formula (I) or to physiologically tolerated, water-soluble-salts thereof ##STR1## and to agents containing said compounds and used for oxidative dyeing of ... | 03/02/2004 |
| 6645991 | v댣 integrin inhibitors The invention describes novel compounds of the formula I which are biologically active as ligands of integrin vଲ.sub.3 in which X, Y, Z, R1, R2, R4 and R5 are as defined in claim 1, and their ... | 11/11/2003 |
| 6632823 | Substituted pyridine compounds useful as modulators of acetylcholine receptors In accordance with the present invention, a novel class of substituted pyridine compounds (optionally containing ether, ester, amide, ketone or thioether substitutions) that promote the release of ligands involved in neurotransmission have been discovered... | 10/14/2003 |
| 6630004 | Oxidation dye composition for keratinous fibers An oxidation dyeing composition for keratinous fibers, in particular hair, comprising, as oxidation base, at least one compound of the formula: ##STR1## where n=0-11, R represents H, amino, a saturated or unsaturated, linear or branched C1 -C | 10/07/2003 |
| 6589967 | Oxime O-ether compounds and fungicides for agricultural and horticultural use The present invention relates to novel oxime O-ether compounds represented by a general formula [I]; ##STR1## wherein R1 represents C1-6 alkyl, C3-6 cycloalkyl, C1-6 alkoxy, etc., m represents an integer of 1 to... | 07/08/2003 |
| 6555561 | Diaminopyridine-containing thiourea inhibitors of herpes viruses This invention provides compounds of formula I having the structure ##STR1## Wherein substitutions at X, G, R1, R2, R3, R4, R5 are set forth in the specification.... | 04/29/2003 |
| 6503933 | 2-pyridylmethylamine derivatives useful as fungicides Compounds of formula (I) and salts thereof as phytopathogenic fungicides wherein A1 is substituted 2-pyridyl; A2 is optionally substituted phenyl; L is --(C.dbd.O)--, --SO2 -- or --(C.dbd.S)--; R1 is hydrogen, o... | 01/07/2003 |
| 6432990 | 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring The present invention provides novel 2-methoxyimino-2-(pyridinyloxymethyl)phenyl acetamide compounds with polyether substituents on the pyridine ring, their use as fungicidal compounds, and their use in fungicidal compositions comprising at least one... | 08/13/2002 |
| 6403617 | Diaminopyridine-containing thiourea inhibitors of herpes viruses Compounds of the formula ##STR1## Useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, humanherpesviruses-6 and -7, and Kaposi herpesvi... | 06/11/2002 |
| 6335354 | Aminopyridines and methods of using thereof This invention relates to aminopyridines of Formula I: ##STR1## or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein R1 -R8, X and m are set in the specification. The invention is also directed to the use of com... | 01/01/2002 |
| 6221886 | Thio acid derived monocyclic N-heterocyclics as anticoagulants This invention is directed to monocyclic N-heterocyclics which are substituted by acyclic or cyclic thio derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invent... | 04/24/2001 |
