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| Number | Title | Issue Date |
| 7365042 | Pyridine-3-sulfonyl compounds as pesticidal agents The present invention describes novel pyridine-3-sulfonyl compounds having the formula (I) wherein R1, R2, R3, R4 and R5 are as defined herein. The present inve... | 04/29/2008 |
| 7342115 | 3-substituted-6-aryl pyridines 3-substituted-6-aryl pyridines of Formula I are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptor. Preferred... | 03/11/2008 |
| 6730668 | 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines The present invention relates to compound which are capable of preventing the extracellular release of inflammatory cytokines, said compounds, including all enantiomeric and diasteriomeric forms and pharmaceutically acceptable salts thereof, have the formula: | 05/04/2004 |
| 6723853 | Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins A method of synthesizing a compound having the formula: from a compound having the formula: wherein R1 is hydrogen, fluorine, chlorine or SiR5R6 | 04/20/2004 |
| 6620827 | PPARγ modulators Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.... | 09/16/2003 |
| 6590103 | Process for preparing alkanesulfonyl pyridines A process for preparing alkanesulfonyl pyridines of the formula 1: ##STR1## is disclosed, wherein R1 is as defined herein. The compounds of formula 1 are useful in the preparation of pyridyl-substituted pyrazoles used in the treatment and allev... | 07/08/2003 |
| 6583161 | Benzenesulfonamides and benzamides as therapeutic agents The invention provides compounds, compositions and methods relating to novel aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particul... | 06/24/2003 |
| 6538016 | -sulfin-and -sulfonamino acid amides The invention relates to -sulfin- and -sulfonamino acid amides of the general formula I ##STR1## including the optical isomers thereof and mixtures of such isomers, wherein n is a number zero or one; R1 is C1 -C12... | 03/25/2003 |
| 6531605 | Process for the manufacture of arylsulfonyl chloride A process is described for the manufacture of a pyridinesulfonyl chloride or a benzenesulfonyl chloride in which the benzene ring bears one or more electron-withdrawing groups, the process comprising reacting a diazonium salt of an aminopyridine or aminob... | 03/11/2003 |
| 6465495 | Preparation of pyridone-based phosphotyrosine mimetics and uses thereof Novel pyridone mimetics are disclosed which are useful for the treatment of SH2 domain related diseases.... | 10/15/2002 |
| 6432880 | Substituted 2-phenylpyridines as herbicides 2-Phenylpyridines I ##STR1## an their salts, wherein R1 to R17, X1 -X3 are as defined in the specification. The compounds are useful as herbicides, desiccants and defoliants.... | 08/13/2002 |
| 6420314 | Substituted 2-phenyl pyridines, their manufacture and use as herbicides Substituted 2-phenylpyridines of the formula I ##STR1## in which the substituents and the index m are defined in the specification.... | 07/16/2002 |
| 6407245 | Substituted thiopyridines Substituted thiopyridines of the general formula I ##STR1## where n is 1 or 2; R1 is chlorine, C1 -C3 -fluoroalkyl, nitro or methylsulfonyl; R2 is a C1 -C10 -alkyl, C2 -C10... | 06/18/2002 |
| 6350876 | 4-chloro-3,5-dimethyl-2-sulfonyl pyridines 2-Sulfonylpyridine derivatives can be industrially produced efficiently by reacting a sulfonyl cyanide derivative with an ,ଲ-unsaturated carbonyl compound and a 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole skeleton can be formed in one step i... | 02/26/2002 |
| 6310214 | Process for the preparation of chloropyridine sulphonic acid chlorides A process is disclosed for preparing chlorinated pyridinesulphonic acid chlorides of the general formula I ##STR1## from hydroxypyridine-sulphonic acids of the general formula II ##STR2## The process generally entails a) passing chlorine gas into a mixtur... | 10/30/2001 |
| 6262273 | Substituted thiopyridines Substituted thiopyridines of the general formula I ##STR1## where n is 1 or 2; R1 is chlorine, C1 -C3 -fluoroalkyl, nitro or methylsulfonyl; R2 is a C1 -C10 -alkyl, C2 -C10... | 07/17/2001 |
| 6200995 | PPAR-γ modulators Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.... | 03/13/2001 |
| 6197962 | Method for producing 2-sulfonylpyridine derivatives and method for producing 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole derivatives 2-Sulfonylpyridine derivatives can be industrially produced efficiently by reacting a sulfonyl cyanide derivative with an , ଲ-unsaturated carbonyl compound and a 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole skeleton can be formed in one step ... | 03/06/2001 |
| 6130335 | N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides N-(Triazoloazinyl)arylsulfonamide compounds, such as 2,6-dimethoxy-N-(8-chloro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)be nzenesulfonamide, 2-methoxy-4-(trifluoromethyl)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimi din-2-yl)pyridine-3-sulfonamide... | 10/10/2000 |
| 6090787 | Antithrombotic agents This invention relates to peptide derivatives, pharmaceutical formulations containing those compound and methods of their use as thrombin inhibitors.... | 07/18/2000 |
| 5959116 | Pyridine-2, 3-dicarboximides their preparation and their use for controlling undesired plant growth A pyridine-2,3-dicarboxylic acid diester of the formula Va ##STR1## where the radicals R2 and R4 have the meanings set out in the specification and where R8 is a C1 -C4 -alkyl, C3 -C | 09/28/1999 |
| 5760029 | Spirocycle integrin inhibitors This invention relates to novel heterocycles, including (S)-2-phenylsulfonylamino-3-8-(2-pyridinylaminomethyl)-!-1-oxa-2-azaspi ro-4,5!-dec-2-en-3-yl!carbonylamino! propionic acid, which are useful as antagonists of the v ଲ | 06/02/1998 |
| 5670528 | Thioamides and their use as crop protection agents Thioamides of the formula I ##STR1## where A, B, R' are hydrogen, cyano, alkyl, alkoxy or halogen, X is .dbd.CHCH3 or .dbd.N--OCH3, R1, R2 - are hydrogen or alkyl, Y is a group ##STR2## --O--CH2,... | 09/23/1997 |
| 5654429 | Method for the preparation of 3-amino-2-chloro-4-alkylpyridines A process for the preparation of a 3-amino-2-chloro-4-alkylpyridine of the formula: ##STR1## wherein R1 is a linear, branched or cyclic hydrocarbon of from one to eight carbon atoms, optionally substituted with one or more electron stabilizing g... | 08/05/1997 |
| 5461045 | Fused benzeneoxyacetic acid derivatives A fused benzeneoxyacetic acid derivative of the formula: ##STR1## wherein ##STR2## is (i) ##STR3## (ii) ##STR4## (iii) ##STR5## or (iv) ##STR6## A is (i) ##STR7## or (ii) ##STR8## R1 | 10/24/1995 |
| 5410063 | Pyridin-2-yl-sulfonamides useful for the preparation of herbicidally active sulfonylureas A compound of the formula II ##STR1## in which R1 is hydrogen, halogen, C1 -C4 alkyl, C1 -C4 alkoxy, C1 -C4 alkylthio, C1 -C4 haloalkoxy or CF3 | 04/25/1995 |
| 5336772 | Method for preparing N-fluoropyridinium salt N-fluoropyridinium salts of the following formula are prepared by reacting a pyridine compound with a Br nsted acid and fluorine, wherein the reaction solvent contains a greater than equimolar amount of the pyridine compound relative to an amount of the B... | 08/09/1994 |
| 5286867 | Substituted 1-sulfonyloxy-2-pyridones and process for preparing them 1-Sulfonyloxy-2-pyridones of the formula I ##STR1## show good radiation sensitivity over a wide spectral range and are therefore valuable as photoactive compounds in radiation-sensitive mixtures.... | 02/15/1994 |
| 5216169 | 3-hydroxypyridineazomethine dye A 3-hydroxypyridineazomethine dye represented by general formula (I) ##STR1## wherein R1 represents an aliphatic group, an aromatic group, or a heterocyclic group; R2 represents an aliphatic group, an aromatic group, a heterocyc... | 06/01/1993 |
| 5198439 | Angiotension II antagonizing pyridine derivatives The invention concerns pharmaceutically useful novel compounds of the formula I, in which R1, R2, R3, R4, R5, R6, R7, X and Z have the various meanings defined herein, and their ... | 03/30/1993 |
| 5187176 | 1-phenyl substituted pyrimidone derivatives Phenyl substituted heterocyclic compounds having insecticidal activity have the formula (I): ##STR1## wherein R1 is an optionally substituted pyridone, thiopyridone, pyrimidinthione, pyrimidinone, pyrazole, imidazole or triazole group; ... | 02/16/1993 |
| 5187170 | Thiocarboxylic esters and fungicides containing them Thiocarboxylic esters of the formula I ##STR1## where the substituents have the following meanings: X is oxygen, sulfur, oxymethylene, methyleneoxy, thiomethylene, methylenethio, ethylene, ethenylene or ethynylene, Y,Z are each sulfur or oxygen, but ... | 02/16/1993 |
| 5149359 | Derivatives from 3,4-dehydro-piperidin-5-one exhibiting a herbicidal activity The present invention relates to derivatives of 3,4-dehydropiperidin-5-one having herbicidal activity. The derivatives have the formula ##STR1## as defined in the claims. The present invention further relates to a herbicidal composition and a method ... | 09/22/1992 |
| 5137877 | Bifunctional linking compounds, conjugates and methods for their production The present invention provides novel N-substituted hydrazine bifunctional compounds, novel N-subhstituted hydrazone derivatives of a cytotoxic reagent incorporating the bifunctional compounds, novel conjugates containing at least one cytotoxic reagent mol... | 08/11/1992 |
| 5120869 | Herbicidal compounds A herbicidal compound of formula (I): ##STR1## wherein X is O, S(O)n or NRa where Ra is H or alkyl and n is 0, 1 or 2; R1 is H or halo; R2 is N or CR3 where R3 is halo or NO... | 06/09/1992 |
| 5112386 | Fungicides Acrylic acid derivatives having the formula (I): ##STR1## and stereoisomers thereof, wherein W is R1 O2 C--C.dbd.CH--ZR2, R1 and R2 are alkyl or fluoroalkyl groups, and Z is oxygen or sulphur, A,... | 05/12/1992 |
| 5079366 | Quarternary pyridinium salts The invention provides novel amino acids and peptides containing them which comprise a dihydropyridine.revreaction.pyridinium salt-type redox system and which provide site-specific and sustained delivery of pharmacologically active peptides to the brain. ... | 01/07/1992 |
| 5055582 | Process for preparing thromboxane A2 antagonists This invention relates to a process for preparing useful thromboxane A2 inhibiting (&#b1;)7-[3-[1-[[(phenylamino)thioxomethyl]hydrazono]ethyl]-1 ,4-bicyclo[2.2.1]hept-2ଲ-yl]-heptenoic acids and useful derivatives ... | 10/08/1991 |
| 5049571 | 1-nitro-2,2-diaminoethylene derivatives There are disclosed novel 1-nitro-2,2-diaminoethylene derivatives of formula I ##STR1## wherein X is chlorine, fluorine, unsubstituted or halogen-substituted C1 -C5 alkyl; unsubstituted or halogen-substituted C1 ... | 09/17/1991 |
| 5008276 | Methyl -(2-substituted)pyrid-3-yl-ଲ-methoxyacrylates, compositions containing them and their use as fungicides Fungicidal compounds of the formula (I): ##STR1## and stereoisomers thereof, wherein K is oxygen or sulphur; Z is optionally substituted aryl or optionally substituted heteroaryl; X is O, S(O)n, NR4, CR1 R2... | 04/16/1991 |
