There are disclosed various compounds of the formula below, ##STR1## where R, R1, W, X, Y and Z are as defined in the specification; which are useful for alleviating various memory dysfunctions such as Alzheimer's disease, as modulators of...
Novel 9-amino-7-(substituted amino)-6-demethyl-6-deoxytetracyclines having activity against a wide spectrum of organisms including organisms which are resistant to tetracyclines are disclosed. Also disclosed are intermediates and methods for making the no...
|5300642||, -disubstituted aromatics and heteroaromatics as cognition enhancers|
Cognitive defeciencies or neurological dysfunction in mammals are treated with ,-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: ##STR1## or a salt thereof wherein X and Y are taken together to form a...
|5286881||Process for producing benzodifuranone compounds useful for dyeing or printing hydrophobic fiber materials|
A benzodifuranone compounds of the formula, ##STR1## wherein R1 and R2 are each independently a naphthyl group or an unsubstituted or substituted phenyl group, which is useful for dyeing or printing hydrophobic fiber materials, ...
1,4-Dihydropyridine derivatives of formula: ##STR1## wherein Ar1 represents an aromatic hydrocarbon group or an aromatic heteromonocyclic or heterobicyclic group containing therein 1 to 3 atoms selected from the group consisting of oxygen,...
|5266707||3,5-dihydroxyheptanoic acid derivatives|
4-hydroxytetrahydropyran-2-one and 3,5-Dihydroxyheptanoic acid derivatives of formula (I) and formula (II) have an inhibition effect on HMG-CoA reductase, a cholesterol value reduction effect, and an antioxidation function, thus serving as cholesterol red...
|5266699||NIR dyes, methods of preparing them and their use|
The compounds of the formula I ##STR1## in which Y and Y1 are each, independently of one another, O, S, NH or N-alkyl, N-cycloalkyl, N-phenyl or N-benzyl, or Y and Y1 are together N-alkylene-N, R and R1 are each, independe...
|5260320||Diaminotrifluoromethylpyridine compounds and phospholipase A2 inhibitor containing them|
A diaminotrifluoromethylpyridine derivative of the formula (I) or its salt: ##STR1## wherein X is --CW1 R1, --COCOR2, --CW1 NHCOR2, --C(.dbd.W1)W2 R3 or --CW1
|5260448||Method for preparing 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease|
A method is provided for preparing 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs which are thromboxane A2 (TXA2) receptor antagonists or combined thromboxane A2 receptor antagonists/thromboxane sy...
|5235072||2-oxabicyclo(2,2,1)heptane derivatives and pharmaceutical|
The invention relates to 2-oxabicyclo[2.2.1]heptane derivatives of formula I ##STR1## as well as their enantiomers, in which, e.g., A means --(CH2)n --, (E)-- or (Z)--CH.dbd.CH--, --C.tbd.C, --O-- or --S--, B means hydrogen, C
|5234900||Herbicidal oxabicyclo ethers|
The present invention relates to novel oxabicyclo ether derivative compounds, compositions containing these ether derivative compounds, and methods of using these compounds or compositions to control the growth of undesired vegetation. More particularly, ...
|5229403||Diaminotrifluoromethylpyridine derivatives and phospholipase A2 inhibitor containing them|
A diaminotrifluoromethylpyridine derivative of the formula (I) or its salt: ##STR1## wherein X is --CW1 R1, --COCOR2, --CW1 NHCOR2, --C(.dbd.W1 (W2 W3 or --CW1
|5223516||3,3,3-trifluoro-2-mercaptomethyl-N-tetrazolyl substituted propanamides and method of using same|
Compounds of the formula ##STR1## wherein Y can be tetrazolyl are disclosed. These compounds are useful as cardiovascular agents....
|5175314||Herbicidal oxatricyclic ethers|
This invention relates to certain herbicidal oxatricyclic ethers, agriculturally suitable compositions thereof and a method for their use as broad spectrum preemergent or postemergent herbicides....
|5166162||Pyridylsulfonylurea and pyridylsulfonylthiourea compounds|
The invention concerns a compound of formula (I) ##STR1## in which: R represents cycloalkyl, bicycloalkyl or polycycloalkyl, X represents oxygen or sulfur, and R1 represents alkyl, cycloalkyl, bicycloalkyl, or polycycloalkyl. Medicaments thereof and use of sam...
|5128348||Bicyclo(3.1.0)hexane amines and bicyclo(4.1.0)-heptane amines as agricultural fungicides|
Certain hexane and heptane amines including geometric and stereoisomers, agricultural compositions containing them and their use as fungicides....
|5089514||3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents|
Certain 3-(phenyl, chroman-2-yl, benzofuran-5-yl, or benzoxazol-5-yl)-2-(hydroxy or mercapto)propionic acid derivatives and analogs are useful as hypoglycemic and hypocholesterolemic agents....
|5075324||Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical composition containing them|
1,4-dihydropyridines of formula I ##STR1## wherein X is --CO2 R1, cyano, nitro, --COCH3 ; each of R and R1, which are the same or different, is a primary, secondary or tertiary, saturated or unsaturated, li...
|5071871||Pharmaceutically useful benzo(ଲ)pyranes and pyranopyridines|
New benz[b]pyranes and pyranopyridines of formula I, ##STR1## wherein the significances of substituents V, T, W, R3 to R5, R9, R10, m, X, Y and Z are given in claim 1 and their N-oxides and their salts and ...
Novel compounds have a formula (I) ##STR1## wherein ##STR2## represents a bicyclo [2,2,1] hept-2Z-ene, bicyclo [2,2,1]heptane, 7-oxa-bicyclo [2,2,1] hept-2Z-ene, 7-oxa-bicyclo [2,2,1] heptane, bicyclo [2,2,2] oct-2Z-ene or bicyclo [2,2,2] o...
|5006549||Novel 7-aroyl-4-hydroxy-3-methyl-benzofurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase|
Novel 7-Aroyl-4-Hydroxy-3-Methyl-Benzofurans of the following general formula (I) are disclosed: ##STR1## The compounds are found to be potent dual inhibitors of cyclooxygenase and 5-lipoxygenase....
|4999362||2-thiomethyl-substituted-1,4-dihydropyridines, method for their preparation and pharmaceutical compositions containing them|
Compounds of formula I ##STR1## wherein R1 is an alkoxycarbonyl group, acetyl, benzoyl, cyano, nitro or aminocarbonyl; R2 is an optionally substituted aryl or hetaryl group; R3 is an alkoxycarbonyl group; $c; is a thio ...
The present invention relates to a compound of the formula: ##STR1## wherein R1 is hydrogen or a lower alkyl; R2 is methyl which is substituted by a carboxy, alkoxycarbonyl, cyano, halogen, aryl or heterocyclic group of C2-...
|4978385||4-halopyridine-3-carboxamide compounds and herbicidal compositions thereof|
A compound of the formual (I) ##STR1## or 1-oxide or salt thereof, wherein R1 is a C1-11 alkyl group, a lower alkenyl group, a phenyl or group which may be substituted, an aralkyl group whose nucleus may be substituted, a haloal...
|4966973||2-substituted coumaran derivatives|
The present invention relates to a compound of the formula ##STR1## wherein R1 stands for hydrogen or a lower alkyl; n denotes an integer of 1 to 6; X stands for an optionally oxidized sulphur atom, oxygen atom or an optionally substituted...
|4966896||Derivative of N-methylcarbamate and insecticide containing the same|
An insecticide having high insecticidal activities against various harmful insects, which is low in toxicity to warm-blooded animals and fishes to be used safely. The insecticide comprises a derivative of 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-(substit...
|4966907||6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis|
Novel position-4 and/or position-6 substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs of the following general structural formula (I) are disclosed: ##STR1## These compounds are found to be potent inhibitors of leukotriene biosynthesis....
|4960909||7-oxabicyclo[2.2.1] heptane sulfonamide derivatives|
Bicyclic sulfonamido derivatives represented by the formula: ##STR1## wherein R1 is a hydrogen or lower alkyl; R2 is an alkyl, substituted or unsubstituted aryl, aralkyl or hetelocycle; R3 is a hydrogen or methyl; X i...
|4959092||Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient|
The present invention relates to a substituted phenyl(or pyridyl)urea compound and a herbicidal composition containing the substituted phenyl(or pyridyl)urea compound as an active ingredient. The compound has the formula: ##STR1## wherein A represent...
Prostaglandin analogues exhibiting activity at thromboxane receptor sites have been prepared....
|4943314||Pyridine-3-carboxamide derivatives having plant growth inhibiting activity|
A compound of the formula (I) ##STR1## or a salt thereof, wherein R is hydrogen atom, phenyl group which may be substituted freely or a group of --(CH2)n --R1 wherein n is an interger from 1 to 3 and R1 is ...
All possible isomeric forms of a compound of the formula ##STR1## wherein A has a structure selected from the group consisting of ##STR2## wherein Y1 and Y2 are individually selected from the group consisting of hydrogen, f...
|4933351||Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis|
Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit the mammalian 5-lipoxygenase enzyme, thus preventing the metabolism of arachidonic acid to the...
|4927838||Pyridine compounds which are useful in treating a disease state characterized by an excess of platelet activating factors|
The invention relates to compounds of the formula ##STR1## wherein Y and Y' are hydrogen or taken together are O or S, *A is paraphenylene or *----(CH2)n --(X)s --(CH2)r ----, X is O, S or --CH.d...
|4923882||Novel amine derivatives, salts thereof and an anti-ulcer agent containing the same|
This invention relates to amine derivatives and salts thereof. These compounds have an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such compound, a process for the preparation thereof and an anti-ulcer ag...
|4920225||Resolution of 1,4-dihydropyridine derivatives|
Optically active compounds of formula 1 ##STR1## wherein R1 is H or lower alkyl; R2 and R6 are each independently lower alkyl, aryl, or arylalkyl; R3 is CN, NO2, CO2 R5, CONHR5
|4916240||Hetero-polycyclic aromatic compounds|
Compounds of the general formula: ##STR1## wherein Z1 and Z2 are each independently --O--, --S-- or --NR5 -- in which R5 is hydrogen, an optionally substituted hydrocarbon group or an acyl group; X1
|4911754||Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds|
This invention relates to aryloxy dihydrobenzofuran, oxoindole or benzofuranone derivatives having herbicidal activity and to the use of such compounds to control the growth of noxious plants, i.e., weeds....
|4906288||Herbicidal pyridyl sulfonamides|
Certain N-[(pyridyl or pyrimidyl)aminocarbonyl]arylsulfonamides, such as the compound methyl 2-[[N-(3-cyano-4,6-dimethylpyridin-2-yl)aminocarbonyl]aminosulfonyl]benzoa te, possess herbicidal activity....
|4886799||Acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone|
The invention relates to new acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone, of general formula I ##STR1## in which: R1 denotes a hydrogen or halogen atom, R2 and R3, which may be identical or different, each...