Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7432288 | Pyrrole-2,5-dione derivatives as Liver X receptor modulators The present invention relates to certain novel compounds of the Formula I to processes for preparing such compounds, to their the utility in modulation of nuclear hormone receptors Liver X Receptor (LXR)α(NR1H3) and/or β(... | 10/07/2008 |
| 7390907 | Vanilloid receptor ligands and their use in treatments Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascu... | 06/24/2008 |
| 7319149 | Chelants and macrocyclic metal complex radiopharmaceuticals thereof Chelants and macrocyclic metal complexes thereof, methods of preparing the chelants and macrocyclic metal complexes, and radiopharmaceutical compositions comprising the macrocyclic metal complexes are disclosed. Methods of using the macrocyclic metal complexes as ra... | 01/15/2008 |
| 7317104 | Chelants and macrocyclic metal complex radiopharmaceuticals thereof Chelants and macrocyclic metal complexes thereof, methods of preparing the chelants and macrocyclic metal complexes, and radiopharmaceutical compositions comprising the macrocyclic metal complexes are disclosed. Methods of using the macrocyclic metal complexes as ra... | 01/08/2008 |
| 7192967 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents The invention relates to new pyridylalkane, alkene, and alkine carboxamides substituted with an imide with a saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group according to general formula (I), wherein the residue E is a cy... | 03/20/2007 |
| 7157561 | Methods of inhibiting transmission of a costimulatory signal of lymphocytes Activated haptens useful for generating immunogens to the HIV protease inhibitor atazanavir, immunogens useful for producing antibodies to atazanavir, and antibodies and labeled conjugates useful in immunoassays for determination of atazanavir. The haptens feature a... | 01/02/2007 |
| 7109186 | HIV integrase inhibitors The present invention describes novel compounds of Formula I which inhibit HIV integrase. The invention also describes compositions and treatments of AIDS or ARC by using these compounds ... | 09/19/2006 |
| 7094860 | Maleimide group-containing polymer particles and method of producing the same The present invention relates to a maleimide group-containing polymer particle containing a crosslinked polymer particle containing a group represented by the following formula (1) and to a method of producing the maleimide group-containing crosslinked polymer parti... | 08/22/2006 |
| 7037880 | Ethylene derivatives and pesticides containing said derivatives Ethylene derivatives of formula (I): where Q is an unsubstituted or substituted phenyl or heterocyclic group, especially a 4-thiazolyl, 1- or 3-pyrazolyl, 1,3-oxazol-4-yl, phenyl or pyridyl group; E is a substituent su... | 05/02/2006 |
| 6939882 | Fungicides Use of compounds of general formula (I) or salts thereof as phytopathogenic fungicides wherein the various radicals and substituents are as defined in the description, pesticidal compositions containing them and method for combatting pests which comprises applying t... | 09/06/2005 |
| 6913748 | Cross-linkers with high reactivity and solubility and their use in the preparation of conjugates for targeted delivery of small molecule drugs Disclosed is a method of making conjugates of cell binding agents and small molecule drugs comprising reacting a cell binding agent with a bifunctional cross-linking moiety to thereby provide the cell binding agent with a reactive disulfide group and then reacting t... | 07/05/2005 |
| 6821992 | Fungicides The invention relates to compounds of general formula I, where A1, R1, R2 and Y are as defined in the description; and to their use as phytopathogenic fungicides. ... | 11/23/2004 |
| 6569855 | Substituted cyclic amine metalloprotease inhibitors The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a stru... | 05/27/2003 |
| 6352566 | Ethers of polyalkyl or polyalkenyl N-hydroxyalkyl succinimides and fuel compositions containing the same Ethers of polyalkyl or polyalkenyl N-hydroxyalkyl succinimides having the formula: ##STR1## or a fuel soluble salt thereof; wherein R is a polyalkyl or polyalkenyl group having an average molecular weight in the range of about 450 to about 5,000; n is an ... | 03/05/2002 |
| 6172005 | Heteroaryl azole herbicides Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful for controlling undesired vegetation ##STR1## and Q, W, X, Y, Z, and R1 through R8 are as defined in the disclosure. Also di... | 01/09/2001 |
| 6133296 | Substituted pyridyl keto enols The invention relates to new pyridyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which V1, V2 or V3 represents nitrogen, Het represents one of the groups ##STR2## A, B, G, W, Z and z have the mean... | 10/17/2000 |
| 6127529 | Metal-chelating 2,6-disubstituted pyridine compounds and their use Bifuncitonal chelating pyridine compound and its use for conferring chelating properties on organic compounds. The pyridine compound has the structure ##STR1## where (i) n is an integer 1 or 2, (ii) R1, R2 and R3 repr... | 10/03/2000 |
| 6121296 | Transition-state inhibitors for nucleoside hydrolase and transferase reactions This invention is directed to transition-state analog compounds and to the use of said compounds as inhibitors of nucleoside hydrolase and transferase enzyme activity of parasites. This invention is further directed to the use of said compounds to treat i... | 09/19/2000 |
| 6060502 | Pesticidal sulfur compounds Pyrazole, pyrrole and imidazole derivatives having formula (I) or (II): ##STR1## wherein .dbd.X is .dbd.NR3, .dbd.O or an electron pair and Q comprises certain pyrazole, pyrrole and imidazole structures which, together with the remaining s... | 05/09/2000 |
| 6057342 | Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(.dbd.NH)NH2 a... | 05/02/2000 |
| 6015904 | Stable reagents for the preparation of radio pharmaceuticals This invention provides novel reagents for the preparation of radiopharmaceuticals useful as imaging agents for the diagnosis of cardiovascular disorders, infection, inflammation and cancer, diagnostic kits comprising said reagents and intermediate compou... | 01/18/2000 |
| 5994377 | Piperidine compounds Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the inventi... | 11/30/1999 |
| 5985815 | Bleach activators New compounds useful as bleach activators as well as new percarboxylic acids, which may be formed as intermediates upon reaction of such activators with peroxygen bleach source in aqueous solution, include nitrogen-containing heterocyclic groups. Preferre... | 11/16/1999 |
| 5935951 | 1-acyl-4-aliphatylaminopiperidine compounds The invention relates to novel 1-acyl-4-aliphatylaminopiperidine compounds of ##STR1## formula (I), in which R1 is a benzoyl, naphthoyl or cycloalkanoyl radical which is unsubstituted or substituted by lower alkyl, lower alkoxy, halog... | 08/10/1999 |
| 5869675 | Lactacystin derivatives Novel lactacystin derivatives other than lactacystin per se, with superior activity for the genesis of neurites and highly selective toxicity and low cytotoxicity as compared with known lactacystin have been prepared, of the formula ##STR1## whe... | 02/09/1999 |
| 5776954 | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use The present invention addresses substituted pyridyl pyrroles, as well as compositions containing such compounds and methods of treatment. The compounds in the present invention are glucagon antagonists and inhibitors of the biosynthesis and action of TNF-... | 07/07/1998 |
| 5773623 | Methine dyes containing a 5- or 6- membered carbocyclic or heterocyclic radical Methine dyes of the formula ##STR1## where K is a 5- or 6-membered carbocyclic or heterocyclic radical, X is nitrogen or a radical of formula C--Q1, and Q1, Q2 and Q3 are each independently of the others hydrogen, ... | 06/30/1998 |
| 5756679 | Derivatized pyridinoline reagent A pyridinoline composition in which pyridinoline is derivatized specifically at its aliphatic hydroxyl group by a selected chemical group is disclosed. In various embodiments, the composition may be used as a standard for HPLC or immunoassay of pyridinoli... | 05/26/1998 |
| 5750706 | Azepanes and their ring homologues having protein kinase inhibiting activity The compounds of formula I ##STR1## wherein R1 -R9, R15, A, X, Y, Z and n have the meaning given in the specification are active as protein kinase inhibitors and can be used as medicaments, particularly for the treatm... | 05/12/1998 |
| 5726324 | 1-(nitroaryl)pyrrole intermediates to pesticidal 1-(haloaryl)pyrroles Process for preparing complex pesticidal 1-(haloaryl)heterocyclic compounds by reacting 1-(nitroaryl)heterocycles with metallic halide salts. 1-(Nitroaryl)pyrrole intermediates useful in said process.... | 03/10/1998 |
| 5703100 | Modulators of acetylcholine receptors In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds... | 12/30/1997 |
| 5681960 | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies The present invention relates to the field of immunoassays for metal ions. The invention presents: metal ion-ligand coordination complexes ("MLC"), novel ligands, antibodies specific for MLC, immunoassays utilizing the foregoing, and methods for selecting... | 10/28/1997 |
| 5670645 | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies The present invention relates to the field of immunoassays for metal ions. The invention presents: metal ion-ligand coordination complexes ("MLC"), novel ligands, antibodies specific for MLC, immunoassays utiliizing the foregoing, and methods for selectin... | 09/23/1997 |
| 5658940 | Succinimide and maleimide cytokine inhibitors Novel succinimides and maleimides are inhibitors of tumor necrosis factor and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is methyl 3... | 08/19/1997 |
| 5656253 | Ligands useful in radiographic imaging The present invention relates particularly to novel pyridine based nitrogen-sulfur ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes, novel aminothiol ligands that are suitable f... | 08/12/1997 |
| 5654122 | N-aminopyridone dyes Pyridone dyes useful for thermal transfer have the formula ##STR1## where R1 is hydrogen or C1 -C4 - alkyl, R2 and R3 are identical or different and each is, independently of the other, hydrogen, subs... | 08/05/1997 |
| 5630996 | Two-step pretargeting methods using improved biotin-active agent conjugates Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related com... | 05/20/1997 |
| 5631172 | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies The present invention relates to the field of immunoassays for metal ions. The invention presents: metal ion-ligand coordination complexes ("MLC"), novel ligands, antibodies specific for MLC, immunoassays utilizing the foregoing, and methods for selecting... | 05/20/1997 |
| 5594011 | Modulators of acetylcholine receptors In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds... | 01/14/1997 |
| 5583147 | Amides for the treatment of atherosclerosis This invention provides amide compounds as inhibitors of acyl-Coenzyme A: cholesterol O-acyltransferase (ACAT), pharmaceutical compositions containing such compounds, processes for the preparation of such compounds, and the use of such compounds as antihy... | 12/10/1996 |
