U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Icon_funbox Bizarre Patents

Patent No. 5508049

Pizza Pie With Concentric Rings of Crust

A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.

Newsletter  PatentStorm News

Make the Most of Our Site

See this month's Top Inventors and Most Cited Patents.

Stay on top of the latest innovations by subscribing to an RSS feed.

Registered users: Manage your profile.

 

Class 546/278.1 - Having -C(=X)-, wherein X is chalcogen, bonded directly to the five- membered hetero ring


Subclass of Class 546 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which -C(=X)-, wherein X is chalcogen
No. of patents: 155
Last issue date: 06/24/2008


1        
NumberTitleIssue Date
7390907Vanilloid receptor ligands and their use in treatments
Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascu...
06/24/2008
73650612-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
Novel compounds are provided which are glycogen phosphorylase inhibitors which are useful in treating, preventing or slowing the progression of diseases requiring glycogen phosphorylase inhibitor therapy such as diabetes and related conditions (such as hyperglycemia...
04/29/2008
7323470Viral polymerase inhibitors
An isomer, enantiomer, diastereoisomer or tautomer of a compound, represented by formula I: wherein wherein A, B, R2, R3, M1, M2, M3, M4, Y1 ...
01/29/2008
7304079Substituted indolealkanoic acids
Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as metho...
12/04/2007
7285551Fused-ring compounds and use thereof as drugs
The present invention provides a fused ring compound of the following formula [I] wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, and a therapeutic agent for he...
10/23/2007
7285545Cytokine inhibitors
Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as...
10/23/2007
7241801Viral polymerase inhibitors
A compound, represented by formula (I): wherein A, B, R1, R2, R3, R5, R6, R7, R9, and R10 are as defined herein, or an enant...
07/10/2007
72237654-phenyl-1-piperazinyl, -piperidinyl and -tetrahydropyridyl derivatives
The present invention relates to substituted 4-phenyl-1-piperazinyl derivatives having the formula I wherein W is C, CH or N, and the dotted line emanating from W indicates a bo...
05/29/2007
7208491N-monoacylated o-phenylenediamines
Mono-acylated o-phenylendiamines derivatives of formula I wherein X and R are as described herein, have been found useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as c...
04/24/2007
7205299Indole derivatives having an apoptosis-inducing effect
The invention relates to indole derivatives which are used as drugs for treating tumor diseases, in particular when there is drug resistance against other active compounds and where there is a metastasizing carcinoma. ...
04/17/2007
7183294Indole derivatives useful for the treatment of diseases
The invention relates to indole derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous...
02/27/2007
7166637Hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them
The invention relates to substituted 4- or/and 7-hydroxyindoles, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active c...
01/23/2007
7161009Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation. ...
01/09/2007
71354723-Heterocyclic benzylamide derivatives as potassium channel openers
The present invention provides novel 3-heterocyclic benzylamides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6
11/14/2006
70675364-,6- or 7-hydroxyindoles with N-oxide groups and the use thereof as therapeutic agents
The invention relates to substituted 4-, 6- or 7-hydroxyindoles with N-oxide groups, process for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4...
06/27/2006
7045544Substituted 2,5-diamidoindoles as ECE inhibitors for the treatment of cardiovascular diseases
The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals ...
05/16/2006
6992092Anti-diabetic agents
The present invention provides compounds of formula (I) the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs; wherein R1, R2
01/31/2006
6962942Azacycloalkanone serine protease inhibitors
The present invention is directed to non-peptidic factor Xa inhibitors which are useful for the treatment of arterial and venous thrombotic occlusive disorders, inflammation, cancer, and neurodegenerative diseases. The factor Xa inhibitors provide compounds having F...
11/08/2005
69583384-,5-,6-and 7-indole derivatives useful for the treatment of CNS disorders
The present invention relates to 4-, 5-, 6- or 7-methylene substituted indolyl derivatives of formula I wherein R is aryl or heteroaryl, where said aryl or heteroaryl groups may be substituted one or more times with a ...
10/25/2005
6949572Triamide-substituted heterobicyclic compounds
The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for...
09/27/2005
6900319Thrombin inhibitors
The invention relates to a compound of the formula I: or a salt thereof with a physiologically tolerated acid, or stereoisomers thereof, wherein R1, R2, A, B, C and D have the meanings described i...
05/31/2005
RE38624Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation
The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation. ...
10/12/2004
6759428Indole nitriles
Compounds of the formula (I) wherein m, n, R1, R2, R3, R4, R5 and R6 are as described herein, together with methods for making the compounds and using the...
07/06/2004
67533422-(1h-indol-3-yl)-2-oxo-acetamides with antitumor activity
2-(1H-Indol-3-yl)-2-oxo-acetamides having antitumor activity, in particular against solid tumors, more precisely colon and lung tumors, of the following formula I: wherein Y is an oxygen of sulfur atom and X, R1, R2, R3, R4
06/22/2004
6727263Indole and 2,3-dihydroindole derivatives, their preparation and use
The present invention relates to indole and 2,3-dihydroindole derivatives having formula (I) or any of its any of its enantiometers or any mixture thereof, or an acid addition salt thereof, wherein A, R1, R
04/27/2004
6638953Indole derivatives as 5-HT receptor antagonist
The invention relates to heterocyclic compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS disorders such as anxiety....
10/28/2003
6602890Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
The invention relates to new hydroxyindoles of the Formula, ##STR1## their use as inhibitors of phosphodiesterase 4 and processes for their preparation....
08/05/2003
6545025Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
The invention relates to nets hydroxyindoles of the Formula, ##STR1## their use as inhibitors of phosphodiesterase 4 and processes for their preparation....
04/08/2003
6545158Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
The invention relates to new hydroxyindoles of the Formula, ##STR1## their use as inhibitors of phosphodiesterase 4 and processes for their preparation....
04/08/2003
6541503Substituted oxindole derivatives as protein tyrosine kinase and as protein serine/threonine kinase inhibitors
Compounds of formula (I): wherein X is N, CH, CCF3, or C(C1-12 aliphatic); R4 is sulfonic acid, C1-12 aliphatic-sulfonyl, sulfonyl-C1-12 aliphatic, C1-12 aliphatic-sulfonyl-C1-6 ...
04/01/2003
6489342Aryloxy piperidinyl indoles for treating depression
This invention provides aryloxy indole derivatives which are useful for the treatment of diseases affected by disorders of the serotonin-affected neurological systems, such as depression and anxiety, the compounds having the formula: ##STR1## wherein...
12/03/2002
6476035Indole and 2,3-dihydroindole derivatives, their preparation and use
The present invention relates to indole and 2,3-dihydroindole derivatives having formula (I) ##STR1## or any of its any of its enantiometers or any mixture thereof, or an acid addition salt thereof, wherein A, R1, R2, R3, ...
11/05/2002
6476028Compounds and methods
A method of treating a CCR5-mediated disease state in mammals which comprises administering to a mammal in need of such treatment, an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof. ##STR1##...
11/05/2002
64172143,3-substituted indoline derivatives
This invention provides compounds of the formula 1: ##STR1## wherein: R1 and R2 are chosen independently from each other from H, OH; OAc; alkylaryl; alkylheteroaryl; 1-propynyl; 3-propynyl; and optionally substituted alkyl, O(alkyl);...
07/09/2002
6353109Certain fused pyrrolecarboxamides; a new class of GABA brain receptor
Disclosed are compounds of the formula ##STR1## or the pharmaceutically acceptable non-toxic salts thereof wherein: W represents substituted or unsubstituted aryl or heteroaryl; T is hydrogen, halogen, hydroxyl, amino or alkyl; X is hydrogen, hydroxy, or lower alky...
03/05/2002
6329523Compounds having a plurality of nitrogenous substitutents
Novel compounds having the formula: ##STR1## wherein the constituent variables are defined herein. The compounds are constructed to include a central aromatic, aliphatic, or heterocyclic ring system. Attached to the central ring system are two linear grou...
12/11/2001
63232283-substituted indole angiogenesis inhibitors
3-Substituted indole carbohydrazides having the formula ##STR1## are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal....
11/27/2001
6306852Indole derivatives useful as endothelin receptor antagonists
##STR1## Compounds of formula (I), and their pharmaceutically acceptable derivatives, wherein R1 and R2 are optional substituents and independently represent C1-6 alkyl, C2-6 alkenyl, optionally substituted by C...
10/23/2001
6303600Substituted azabicyclic compounds
This invention is directed to certain physiologically active compounds of formula (I) ##STR1## wherein ##STR2## represents a bicyclic ring system, of about 10 to about 13 ring members, in which the ring ##STR3## is an azaheterocycle, and the rin...
10/16/2001
6277878Substituted indole compounds as anti-inflammatory and analgesic agents
This invention provides a compound of the following formula: ##STR1## or the pharmaceutically acceptable salts thereof wherein R1 is H or C1-4 alkyl; R2 is C(.dbd.L')R3 or So2 R4 ; Y is a d...
08/21/2001
1        
 
Sign InRegister
Username  
Password   
forgot password?