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| Number | Title | Issue Date |
| 8178682 | Process for making organic compounds and the organic compounds made therefrom An organic compound of formula E is made from a process comprising: reacting a compound of formula A and a compound of formula B to form a compound of formula C; and ... | 05/15/2012 |
| 7999109 | CCR9 inhibitors and methods of use thereof The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compound... | 08/16/2011 |
| 7932393 | Insecticidal (heteroarylalky)alkane thio and oxo amine derivatives Certain novel N-(heteroarylalkyl)alkanediamine derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula I: wherein Ar, a, b, c, T, W, Y, R, Rf, Rg, Rh, Ri, R | 04/26/2011 |
| 7858799 | Ionic organic compound An ionic organic compound having a repeating unit of formula (I) can be synthesized easily from a readily available organic compound through a small number of reaction steps, can be produced without any purification technique such as chromatography, and can be used ... | 12/28/2010 |
| 7816534 | Substituted amides Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are... | 10/19/2010 |
| 7777043 | Compound, charge transporting material and organic electroluminescent element An object of the invention is to provide a charge transporting material having an excellent heat resistance, excellent filming properties, an excellent charge transporting ability, and excellent light-emitting characteristics and, also, to provide an organic electro... | 08/17/2010 |
| 7632950 | Pyridyltetrahydropyridines and pyridylpiperidines and method of manufacturing them The present invention provides pyridine derivatives useful as intermediates of drugs and agricultural chemicals, electrophotographic receptors, dyes and so on. More specifically, the invention relates to novel pyridyltetrahydropyridines and novel pyridylpiperidines,... | 12/15/2009 |
| 7560563 | Process for producing 2-substituted pyridine derivative The present invention provides a method of producing a pyridine derivative having a substituent at the 2-position of a heterocyclic structure conveniently and with fine selectivity. The present invention relates to a production method of a pyridine derivative having... | 07/14/2009 |
| 7524966 | Method for preparing ladderanes Ditopic molecules in the form of linear reaction templates have been used to construct ladder-like hydrocarbons known as [n]-ladderanes (n=3,5). The templates assemble and position reactant molecules in the solid state by way of hydrogen bonds for [2+2] photodimeriz... | 04/28/2009 |
| 7427693 | Polar liquid crystal Compounds that are useful in compositions for flat panel displays, for example, are provided. The compounds provided are polar, and are useful in low threshold voltage mixtures. The compounds provided have the general structure: CpCOCH2[A] | 09/23/2008 |
| 7414359 | Low work function metal complexes and uses thereof The present invention provides conductive metal-ligand coordination complexes that are useful in a variety of electronic devices. For example, such complexes are useful in organic light emitting devices composed of one or more layers of organic material between two ... | 08/19/2008 |
| 7410979 | Synergistically effective combinations of dihaloacetamide compounds and interferon or ribavirin against HCV infections The present invention relates to anti-HCV dihaloacetamide compounds in synergistic combination with an interferon and/or ribavirin and pharmaceutical compositions thereof for inhibition of the replication of HCV virus. The present invention also relates to the use o... | 08/12/2008 |
| 7388021 | Urea antagonists of P2Yreceptor useful in the treatment of thrombotic conditions The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating disease... | 06/17/2008 |
| 7371763 | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas The invention relates to a group of quinolyl, isoquinolyl and pyridyl ureas, their the use in treating raf mediated diseases, and pharmaceutical compositions which contain these ureas for use in such therapy. ... | 05/13/2008 |
| 7351826 | Aryl acid pyrimidinyl methyl amides, pyridazinyl methyl amides and related compounds The invention provides compounds of Formula (I) that bind to GABAA receptors. In the above formula, variables are defined herein. Such compounds may be used to modulate ligand binding to GABAA receptors in vivo or in vitro, and are particularly... | 04/01/2008 |
| 7326723 | Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; n is an ... | 02/05/2008 |
| 7319149 | Chelants and macrocyclic metal complex radiopharmaceuticals thereof Chelants and macrocyclic metal complexes thereof, methods of preparing the chelants and macrocyclic metal complexes, and radiopharmaceutical compositions comprising the macrocyclic metal complexes are disclosed. Methods of using the macrocyclic metal complexes as ra... | 01/15/2008 |
| 7304066 | Pyridyl cyanoguanidine compounds Compounds according to formula (I) wherein R1 represents hydrogen, halogen or one or more straight or branched, saturated or unsaturated C1-6 hydrocarbon radical, optionally substituted with halogen, h... | 12/04/2007 |
| 7291739 | Chiral catalysts for asymmetric acylation and related transformations A chiral catalyst comprising a 3, 4-disubstituted pyridine, or a salt, N functionalised derivative, dimer or oligomer thereof, wherein the 3-substituent is substantially hindered from rotation about the bond (sp2-sp2 biaryl axis) linking it to ... | 11/06/2007 |
| 7291631 | CXCR4 chemokine receptor binding compounds The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R1, R2 and R3 are substituents. The present invention als... | 11/06/2007 |
| 7247735 | Octupolar molecules used as organic semiconductors In the case of the materials according to the invention, the charge carrier mobility in the correspondingly prepared films is achieved if the molecules are composed in such a way that side chains—consisting of conjugated aromatic or heteroaromatic systems—are at... | 07/24/2007 |
| 7244748 | Pyridines for treating injured mammalian nerve tissue The invention provides novel pyridines, pharmaceutical compositions comprising such pyridines, and the use of such compositions in treating injured mammalian nerve tissue, including but not limited to an injured spinal cord. In one embodiment, the compounds, composi... | 07/17/2007 |
| 7241758 | Compounds useful as anti-inflammatory agents Disclosed are novel aromatic compounds of the formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory disease... | 07/10/2007 |
| 7238714 | Aryl or heteroaryl amide compounds This invention provides a compound of the formula (I): wherein A represents a phenyl group or the like: B represents an aryl or the like: E represents a 1,4-phenylene group; R1 and R2 indepe... | 07/03/2007 |
| 7235658 | Imidazol derivatives as Raf kinase inhibitors Compounds of formula (I): wherein X is O, CH2, S or NH, or the moiety X—R1 is hydrogen; V is CH or N; R1 is ... | 06/26/2007 |
| 7226935 | Hypoglycemic agent A zinc(II) complex which is lowly toxic, has high insulin-like activity, and is effectively usable as a hypoglycemic agent for the prevention or treatment of diabetes; a hypoglycemic agent containing the complex; a medicinal preparation which contains the complex an... | 06/05/2007 |
| 7217299 | Dye composition comprising at least one direct dye of the azo-pyridinio-pyridone family and at least one different synthetic dye, and process The present invention relates to a dye composition comprising, as direct dye, at least one dye of the azo-pyridinio-pyridone family and at least one synthetic dye different from the first dye. The invention also relates to a process for dyeing keratin fibers,... | 05/15/2007 |
| 7211578 | Nitrogenous tetrahydropyridyl-alkyl-heterocycles with TNF activity This invention relates to nitrogenous (tetrahydropyridyl)(alkyl)heterocycles, to pharmaceutical compositions comprising them, to processes for preparing them and to the method of use thereof in the treatment of pain and diseases related to immune and inflammatory di... | 05/01/2007 |
| RE39575 | Substituted thioacetamides The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases. ... | 04/17/2007 |
| 7202093 | Method for labeling phosphorylated peptides, method for selectively adsorbing phosphorylated peptides, complex compounds used in the methods, process for producing the complex compounds, and raw material compounds for the complex compounds Provided are a method for easily detecting phosphorylated peptides, namely, proteins, in samples derived from living organisms or the like, a method for selectively adsorbing the phosphorylated peptides, and compounds that are highly coordinated to the phosphorylate... | 04/10/2007 |
| 7202260 | VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridones Novel VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridones and their use as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are selected. ... | 04/10/2007 |
| 7199136 | 1,4-dihydro-1,4-diphenylpyridine derivatives The invention relates to novel 1,4-dihydro-1,4-diphenylpyridine derivatives of formula (I) wherein the variable groups are as defined in the text and claims. Processes for their preparation, pharmaceutical compos... | 04/03/2007 |
| 7173046 | CD40:CD154 binding interrupter compounds and use thereof to treat immunological complications The present invention relates to novel CD40:CD154 binding interrupter compounds and use of these compounds and pharmaceutical compositions comprising them, to treat conditions associated with inappropriate CD154 activation in a subject. Specifically, this invention ... | 02/06/2007 |
| 7157473 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection The present invention relates to pyridyl substituted heterocycles and hydro isomers thereof and pharmaceutical compositions thereof that inhibit replication and/or proliferation of HCV virus. The present invention also relates to the use of the pyridyl heterocycles ... | 01/02/2007 |
| 7148282 | Composite of high melting polymer and nanoclay with enhanced properties A composite of a polyester, e.g., a polycarbonate, and a nanoclay (layered silicate) cation exchanged with a quaternized copolymer of styrene and 2-(dimethylamine) ethyl methacrylate is provided, the composite being useful for preparing injection molded objects and ... | 12/12/2006 |
| 7129252 | Six membered amino-amide derivatives an angiogenisis inhibitors The present invention relates to six membered amino-amide derivatives, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis and/or increased vascul... | 10/31/2006 |
| 7129235 | Amides useful for treating pain The present invention relates to compounds of formula (I-VII) or a pharmaceutically acceptable salt or prodrug thereof, in which A, L, R6, R7 and R8 are defined herein. The presen... | 10/31/2006 |
| 7109218 | Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same Compounds of the formula (I) a process for their preparation and their use as medicaments are described. ... | 09/19/2006 |
| 7109220 | Amino substituted pyridinyl methanone compounds useful in treating kinase disorders The present invention provides amino substituted pyridinyl methanone compounds; pharmaceutical compositions comprising the compounds and methods of synthesis thereof. The compounds, which are cyclin dependent kinase (CDK) inhibitors, can be used to treat or ameliora... | 09/19/2006 |
| 7087603 | Pyrazole compounds useful as protein kinase inhibitors This invention describes novel pyrazole compounds of formula IV: wherein Z1 or Z2 is nitrogen, Q is —S—, —O—, —N(R4)—, —C(R6′)2—, 1,2-cyclo... | 08/08/2006 |
