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| Number | Title | Issue Date |
| 7235173 | Hydrotreating catalyst that contains a nitrogen-containing organic compound and its use A hydrotreating catalyst that contains at least one element of group VIB and/or group VIII of the periodic table and optionally phosphorus and/or silicon, with an organic compound as an additive that contains at least one nitrogen atom, is used for the transformatio... | 06/26/2007 |
| 7161172 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds The present invention is generally directed to electroluminescent Ir(III) compounds, the substituted 2-phenylpyridines, phenylpyrimidines, and phenylquinolines that are used to make the Ir(III) compounds, and devices that are made with the Ir(III) compounds. ... | 01/09/2007 |
| 7148354 | Process for preparation of donepezil An efficient process for preparation of donepezil is provided. In one embodiment, the process for preparation of donepezil includes suspending a catalyst, which is palladium metal on carbon and the compound of the structure | 12/12/2006 |
| 7147936 | Layer configuration with improved stability to sunlight exposure A layer configuration on a support, the layer configuration comprising a layer containing a polymer containing optionally substituted 3,4-alkylenedioxythiophene structural units, in which the two alkoxy groups may be the same or different or together represent an op... | 12/12/2006 |
| 7138523 | Preparation of 4-(4-fluorophenyl)-N-alkylnipecotinate esters, 4-(4-fluorophenyl)-N-arylnipecotinate esters and 4-(4-fluorophenyl)-N-aralkylnipecotinate esters A process for the industrial scale manufacture of 4-(4-fluorophenyl)-N-alkylnipecotinate esters by the addition of 4-fluorophenylmagnesium halide in tetrahydrofuran to 3,4-unsaturated-3-piperidine esters. ... | 11/21/2006 |
| 7077873 | Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye A subject-matter of the disclosure is a novel composition for the dyeing of human keratinous fibres, for example, the hair, comprising a monocationic monoazo dye of formula (I) W1-N═N—W2-NW3-W4-W5, the dyeing processes employing it, the use of the dyes of formul... | 07/18/2006 |
| 7067535 | 5-Phenylbenzylamine compounds, process for their production and intermediates for their synthesis The present invention relates to a 5-phenylbenzylamine compound represented by the formula [1]: wherein Ring A represents a phenyl group having a substituent(s), Ra | 06/27/2006 |
| 7056600 | Layer configuration comprising an electron-blocking element A layer configuration on a support, the layer configuration comprising a non-photoactive element exclusive of poly(3,4-alkylenedioxythiophene)s and poly(3,4-dialkoxythiophene)s, the element containing a first polymer containing structural units according to formula ... | 06/06/2006 |
| 7034041 | Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine (compounds), methods for the production thereof, pharmaceutical compositions containing said compounds, and methods of treatment of pain and other diseases using the pharmaceutical compositions. | 04/25/2006 |
| 6989449 | Chlorohydrin and cationic compounds having high affinity for pulp or paper Selected chlorohydrin and cationic compounds containing nitroxide or hydroxylamine moieties are effective in stabilizing pulp or paper, especially pulp or paper containing lignin, against yellowing and discoloration due to the adverse effects of light. These compoun... | 01/24/2006 |
| 6962997 | Process and intermediates for resolving piperidyl acetamide steroisomers Processes and intermediates for preparing 2-substituted piperidines such as 2-substituted d-threo piperidines are provided, including processes and intermediates for resolution of piperidyl acetamide stereoisomers. ... | 11/08/2005 |
| 6953856 | Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI) A process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine hydrochloride (Donepezil HCl) is disclosed. 5,6-Dimethoxy-2-(pyridin-4-yl) methylene inda-1-one is hydrogenated with a noble metal catalyst or a non-oxide derivative of a ... | 10/11/2005 |
| 6909023 | Production method for benzenedimethanol compound To provide a novel method for producing a fluorinated benzenedimethanol compound useful as a starting material or an intermediate in the production of agricultural or medicinal chemicals in an industrially advantageous manner. A method for producing a fluorin... | 06/21/2005 |
| 6686503 | Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries The invention relates to methods of synthesizing libraries of diverse and complex highly substituted 2,4-dioxopiperidine compounds of the general formula: ##STR1## wherein R1, R2 and R3 are as herein described, novel ... | 02/03/2004 |
| 6649765 | Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL) A process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (Donepezil HCl). 5,6-Dimethoxy-2-(pyridin-4-yl)methylene inda-1-one is hydrogenated with a noble metal oxide catalyst in an organic solvent at ... | 11/18/2003 |
| 6617454 | Process for the preparation of amine oxides The present invention provides a process for the preparation of amine oxide by reacting a tertiary or a secondary amine with hydrogen peroxide as an oxidant in the presence of a recyclable heterogeneous catalyst comprising a layered double hydroxide excha... | 09/09/2003 |
| 6583286 | Method for hydrogenating unsaturated heterocyclic compounds A process for hydrogenating an unsaturated heterocyclic compound or a mixture of two or more thereof by contacting the unsaturated heterocyclic compounder the mixture of two or more thereof with a hydrogen-containing gas in the presence of a catalyst comp... | 06/24/2003 |
| 6511991 | Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing... | 01/28/2003 |
| 6458954 | Process for preparing piperidines Piperidines are prepared in an advantageous manner by catalytic hydrogenation of activated pyridines in the presence of palladium catalysts if the palladium catalyst is palladium-on-carbon and the solvents are aromatic hydrocarbons.... | 10/01/2002 |
| 6437136 | Process for the preparation of (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)piperidine Disclosed is a method for producing (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperidine characterized in that 1-methyl-piperidine-4-one is converted into hydrobromide, subsequently transformed with bromine into 3(R,S)-bromine-1-methyl-4-o... | 08/20/2002 |
| 6348630 | Method for purifying hexamethylenediamine in mixtures of hexamethylenediamine and an unsaturated cyclic imine The level of an unsaturated cyclic imine (I) of the formula (I) ##STR1## where R1 is alkenyl having 3, 4, 5, 6, 7, 8, 9, 10, 11 carbon atoms belonging to the ring system, in a mixture comprising hexamethylenediamine and an imine (I) is reduced ... | 02/19/2002 |
| 6268501 | Process for the preparation of hydroxyethylcyclohexanes and hydroxyethylpiperidines Hydroxyethylcyclohexanes which can optionally contain a nitrogen atom in the cyclohexane ring are obtained in a particularly selective manner by catalytic hydrogenation of the corresponding hydroxyethylbenzene or hydroxyethylpyridines when ruthenium which... | 07/31/2001 |
| 6258955 | Process for preparing 2-piperidineethanol compounds Described are preferred processes for producing 2-piperidineethanol compounds by hydrogenation of corresponding 2-pyridineethanol compounds. The preferred processes are conducted in the presence of an amine other than said reactant or product, and a hydro... | 07/10/2001 |
| 6225473 | Method for producing (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperidine Disclosed is a method for producing (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperidine characterised in that 1-methyl-piperidine-4-one is converted into hydrobromide, subsequently transformed with bromine into 3(R,S)-bromine-1-methyl-4-o... | 05/01/2001 |
| 6180759 | Process for the preparation of azacycloalkylakanoyl pseudotetrapeptides This invention is directed to a process for preparing a pseudotetrapeptide of formula I ##STR1## or a salt or prodrug thereof wherein ##STR2## is optionally nitrogen protected azaheterocyclyl; ##STR3## is a single or double bond; q is 1-5; B is alkyl... | 01/30/2001 |
| 6172233 | Process for making paroxetine Compounds of structure (2) are prepared by reaction of an arecoline analogue of structure(4) with an organometallic compound containing an X-substituted phenyl group, such as a compound of structure (3). ##STR1## Suitably the compound of structure (3) is ... | 01/09/2001 |
| 6080863 | Process for producing piperidine A process for activating a hydrogenation catalyst in the presence of an activation agent containing a piperidine compound is disclosed. The thus-activated hydrogenation catalyst is employed as a hydrogenation catalyst in the hydrogenation of a pyridine co... | 06/27/2000 |
| 6018048 | Noble metal Raney catalysts and preparation of hydrogenated compounds therewith Noble metal, particularly ruthenium, Raney catalysts having the property of catalyzing the hydrogenation of (1) aromaticity-exhibiting ring portions of organic compounds, (2) carboxylic acids and their ester portions (carbonyl ester groups), (3) ring port... | 01/25/2000 |
| 5962689 | Stereoselective and useful preparation of 3-substituted 4-aryl piperidine compounds This invention relates to new stereoselective processes for preparing 3-substituted-4-aryl piperidines and methods for controlling the absolute stereochemistry at the C-3 and C-4 positions of the piperidine ring. Compounds of this type are key intermediat... | 10/05/1999 |
| 5856492 | Efficient synthesis of a chiral mediator An efficient method for the quantitative preparation and isolation of a compound of formula I ##STR1## or its enantiomer, a chiral mediator used in enantioselective synthesis.... | 01/05/1999 |
| 5789596 | Process for the preparation of 1-acyl-4-arylpiperidines 1-Acyl-4-arylpiperidines of the general formula: ##STR1## wherein R1 is an aryl group optionally substituted by one or more C1-6 -alkyl groups, C1-6 -alkoxy groups, benzyloxy groups or C1-6 -alkylthio group... | 08/04/1998 |
| 5710277 | Process for R (+) 1,2,3,6-tetrahydro-4-phenyl-1-(3-phenyl-3-cyclohexen-1-yl)methyl!pyridi ne, a central nervous system agent An improved process for the preparation of R(+)1,2,3,6-tetrahydro-4-phenyl-1-(3-phenyl-3-cyclohexen-1-yl)methyl!pyri dine by a novel synthesis is described where 5-oxo-3-phenyl-3-cyclohexene-carboxylic acid is converted in five operations to the des... | 01/20/1998 |
| 5686616 | Process for preparing an optically active amine A novel process for preparing an optically active amine by asymmetric hydrogenation of an imine compound, such as an imine compound prepared by condensing benzylamine and acetophenone, in the presence of a catalytic amount of an iridium-optically active p... | 11/11/1997 |
| 5686615 | Stereoselective preparation of substituted piperidines Novel processes are disclosed for the stereoselective preparation of substituted piperidine derivatives of the formulae ##STR1## wherein R1 and R2 are defined as below, useful as substance P receptor antagonists and in treating ... | 11/11/1997 |
| 5663350 | Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists The present invention relates to a novel process for the preparation of highly potent histamine receptor antagonists, in particular histamine H3 -receptor antagonists. Also disclosed is a novel process for the preparation of intermediates usefu... | 09/02/1997 |
| 5663349 | Preparation of substituted piperidenes Novel processes are disclosed for the preparation and resolution of substituted piperidines of the formula ##STR1## wherein R1 and R2 are defined as below, and related compounds, as well as novel intermediates used in such proce... | 09/02/1997 |
| 5663351 | Process for the continuous preparation of 2,2,6,6-tetramethylpiperidine Process for the continuous preparation of 2,2,6,6-tetramethylpiperidine. The reduction of triacetonamine with hydrazine also succeeds continuously by reactive distillation if the hydrazone is first formed and this is continuously transported to the distillatio... | 09/02/1997 |
| 5659040 | Process for the preparation of N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulphonamide A process for the preparation of the compound of formula (I) ##STR1## or a salt thereof which comprises reducing the compound of formula (II) ##STR2## or a salt thereof. The novel intermediate of formula (II) and processes for preparing it are a... | 08/19/1997 |
| 5606064 | Process for the preparation of benzyl-piperidylmethyl-indanones The invention relates to a new process for the preparation of benzyl-piperidylmethyl-indanones known as medicaments, which is characterized in that the appropriately substituted pyridinium salts are hydrogenated.... | 02/25/1997 |
| 5374728 | Process for the preparation of 2-aminomethylpiperidine A process for the preparation of 2-aminomethylpiperidine by catalytic hydrogenation of 2-cyanopyridine in the presence of a cobalt-containing catalyst at elevated temperature and under elevated pressure. The reaction can be carried out either in two steps... | 12/20/1994 |