Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 4942260 | Amine oxide process with CO2 and aluminum Amine oxides which have low levels of nitrosamines or are substantially-free of nitrosamines are made by reacting tert-amines with hydrogen peroxide in the presence of carbon dioxide and aluminum metal.... | 07/17/1990 |
| 4937336 | Process for the preparation of hexamethylene imine A process for the preparation of hexamethylene imine from hexamethylene diamine by the vapor phase reaction in the presence of water, hydrogen, and a palladium catalyst.... | 06/26/1990 |
| 4929733 | Preparation of N-heterocycles N-heterocycles of the general formulae (I) and (II) ##STR1## where R1 and R4 to R9 are each hydrogen, alkyl, aryl, aralkyl, alkylaryl or cycloalkyl and R2 and R3 are each an alkyl, alkylaryl, sub... | 05/29/1990 |
| 4921962 | Process for preparing N-hydrocarbyloxy derivatives of sterically hindered amines N-hydrocarbyloxy compounds of the formula ##STR1## where E1, E2, E3 and E4 are independently an organic radical so that the carbon atoms to which they are attached are each a quaternary carbon, R is a hydro... | 05/01/1990 |
| 4918194 | Process for the synthesis of a N,N-dialkyl-hydroxylamine The invention relates to a process for the synthesis of an N,N-dialkyl-hydroxylamine by reaction of the corresponding dialkylamine with H2 O2, said reaction being carried out in the presence of a catalyst based on titanium-silicalite... | 04/17/1990 |
| 4912220 | Processes for making nitroaryl carbonyl compounds and nitrodihydroaryl carbonyl intermediates thereto Nitroaryl carbonyl Formula (IIA) compounds, their nitrodihydroaryl carbonyl Formula (I) intermediates, processes for preparing Formula (II) compounds, and a process for preparing Formula (I) compounds, wherein each process comprises the reaction of a nitr... | 03/27/1990 |
| 4912216 | Method for production of perfluoro-(N-vinylamine) compounds A perfluoro-(N-vinylamine) compound containing a >NCF.dbd.CF2 group is produced from a perfluoro-compound containing a group of the general formula: ##STR1## (wherein X stands for a fluorine atom or a --OM group having an alkali or al... | 03/27/1990 |
| 4910304 | Preparation of N-substituted cyclic amines N-substituted cyclic amines of the general formula I ##STR1## where A is an alkylene group or a --(CH2)n --[--O--(CH2)m ]r group which may be monosubstituted or polysubstituted by radicals R with... | 03/20/1990 |
| 4902712 | Fluoroalkane derivatives The invention describes the novel compound 4(Z)-6-([2,4,5-cis]-4-o-hydroxyphenyl-2-trifluoromethyl-1,3-dioxan-5-yl)he xenoic acid of formula I and its pharmaceutically acceptacle salts and pharmaceutical compositions, which are of value in treating certain... | 02/20/1990 |
| 4900832 | Process for the catalytic animation of alcohols and diols using non-acidic hydroxyapatite catalysts The present invention relates to a process for the catalytic amination of 1° and 2° alcohols and diols wherein an amine is reacted with an alcohol or diol in the presence of a non-acidic cationic hydroxyapatite catalyst. A typical reaction includes the ... | 02/13/1990 |
| 4889656 | Perfluoro(cycloaliphatic methyleneoxyalkylene) carbonyl fluorides and derivatives thereof Perfluoro(cycloaliphatic methyleneoxyalkylene) compositions are provided. These compositions comprise perfluoro(cycloaliphatic methyleneoxyalkylene) carbonyl fluoride compounds having (a) a perfluorocycloaliphatic moiety which can have up to two perfluoro... | 12/26/1989 |
| 4879327 | New phosphorous acid salts, compositions containing them, and their application as fireproofing agents The invention relates to amine salts of phosphorous acid having a structure of the s-triazine, 1,2,4-triazole, benzimidazole, heptazine, pyrimidine, or piperazine type which may be combined with a polyhydroxylated compound as fireproofing agents for plast... | 11/07/1989 |
| 4876347 | Methine dyes having a pyridyl group and a pyridyl or a quinolinyl group Methine dyes (I) which conform in one of their tautomeric forms to the general formula ##STR1## where Y1 is in both or either case an electron-attracting group and the other Y1 is hydrogen, Y2 is in each case, indepen... | 10/24/1989 |
| 4863966 | Pesticidal amines Compounds of formula (I) are pesticides having activity against arthropods: ##STR1## wherein R1, R2 and R3 are H, alkyl, alkoxy, halo, cyano or trifluoromethyl, or two of R1, R2 and R3 are ... | 09/05/1989 |
| 4861890 | Isomerization A process for producing chiral enamines by isomerizing a beta, gamma unsaturated amine with a rhodium-diphosphine complex with the addition of an achiral triarylphosphine and, if desired, hydrolyzing the compound of the enamine I obtained to the correspon... | 08/29/1989 |
| 4855486 | Blocked, marked amino acids A method is provided for quantitatively monitoring the deprotection and coupling reactions employed in the solid phase synthesis of peptides. The method entails synthesizing a peptide on a support matrix that has a first marker associated therewith. The a... | 08/08/1989 |
| 4841060 | Vapor-phase intramolecular dehydration reaction of alkanolamines Catalytic vapor phase intramolecular dehydration reaction of an alkanolamine represented by the general formula ##STR1## wherein each of R and R' is selected from hydrogen, a methyl group and an ethyl group, and n is an integer of 2 to 5, to convert ... | 06/20/1989 |
| 4841061 | Process for producing cyclic amines A process for producing a cyclic amine represented by the general formula ##STR1## wherein each of R and R' is selected from hydrogen, a methyl group and an ethyl group, and n is an integer of 2 to 5, which comprises vapor-phase intramolecular dehydr... | 06/20/1989 |
| 4833248 | Catalyst for vapor-phase intramolecular dehydration reaction of alkanolamines A catalyst for the vapor phase intramolecular dehydration reaction of an alkanolamine represented by the general formula ##STR1## wherein each of R and R' is selected from hydrogen, a methyl group and an ethyl group, and n is an integer of 2 to 5, to... | 05/23/1989 |
| 4827031 | Process for preparing amines from olefins with ammonium halide catalysts The process for preparing aliphatic and aromatic amines by reacting an olefin with either ammonia, a primary amine, or a secondary amine at elevated temperature in the presence of an ammonium halide catalyst, preferably a catalyst-promoter combination, is... | 05/02/1989 |
| 4803220 | Pharmaceutical agents The invention concerns the novel racemic and laevorotatory optically active forms of the thromboxane A2 antagonist 5(Z)-7-([ 2,4,5-cis]-4-o-hydroxyphenyl-2-trifluoromethyl-1,3-dioxan-5-yl)heptenoic acid of formula I, their salts, pharmaceutical... | 02/07/1989 |
| 4798894 | Gem cyclodialkylation of amines and amides Compounds containing at least one N,N-dialkylatable amino or amido group (e.g., aniline, dodecylamine, acetamide) are converted in a highly efficient manner into gem cyclodialkylated compounds by reaction with an unstrained cyclic ether (e.g., tetrahydrof... | 01/17/1989 |
| 4766235 | Unsaturated camphor derivatives, processes for preparing the same and pharmaceutical and cosmetic compositions containing the same Unsaturated camphor derivatives have an activity in the topical and systemic treatment of acne, psoriasis and other dermatological disorders.... | 08/23/1988 |
| 4757144 | Preparing tertiary amine from formaldehyde and primary and/or secondary amine A tertiary amine is effectively prepared by reacting a primary or secondary amine with formaldehyde in the presence of a palladium or platinum catalyst at a hydrogen pressure of 3 to 50 kg/cm2 (gauge pressure) at a temperature of 80° to 180° C., by cont... | 07/12/1988 |
| 4755601 | Nonyl prenyl-N heterocyclics Nonyl prenyl-N heterocyclic compounds are prepared, useful as antivirals.... | 07/05/1988 |
| 4755604 | Preparation of 3-methylpiperidine 5-Membered, 6-membered or 7-membered cyclic imines are prepared by hydrogenating a C2 -C4 -alkanedinitrile in the liquid phase, at from 180° to 300° C. and under superatmospheric pressure, in the presence of a catalyst, by a proces... | 07/05/1988 |
| 4747965 | Modified succinimides Disclosed are additives which are useful as dispersants in lubricating oils, gasolines, marine crankcase oils and hydraulic oils. In particular, disclosed are multiply adducted alkenyl or alkyl succinimides which contain carbamate functionalities.... | 05/31/1988 |
| 4739051 | Preparation of morpholine Morpholine and other cyclic imines are obtained by reacting diethylene glycol and other appropriate diols with ammonia under hydrogenating conditions in the gas phase in the presence of a catalyst which contains copper, a smaller amount of nickel and alum... | 04/19/1988 |
| 4721794 | Substituted thiophene-2-sulfonamide antiglaucoma agents Thiophene-2-sulfonamides with a 5-alkyl-S(O)n -substituent are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.... | 01/26/1988 |
| 4695631 | Process for the preparation of enamines or imines A process for the preparation of enamines or imines by isomerization of allylamine derivatives is described. Allylamine derivatives represented by formula (I): ##STR1## are isomerized using as a catalyst a rhodium complex represented by formula ... | 09/22/1987 |
| 4680291 | Propenylamines, processes for their production and pharmaceutical compositions containing them The present invention provides propenylamines useful as anti-mycotic agents.... | 07/14/1987 |
| 4678638 | Highly branched amino hexahydropyridines This invention relates to amino hexahydropyridines, and to the preparation and use thereof as corrosion inhibitors.... | 07/07/1987 |
| 4665185 | Process for preparing nitroxyls of sterically hindered amines Nitroxyls of the formula ##STR1## where E1, E2, E3 and E4 are independently an organic radical so that the carbon atoms to which they are attached are each a quaternary carbon and T is a divalent radical ar... | 05/12/1987 |
| 4656282 | Preparation of substituted piperidines Piperidines substituted in the 3- and/or 4-position are prepared by reacting a glutardialdehyde substituted in the 2- and/or 3-position with ammonia or a primary amine and hydrogen at elevated temperature and under superatmospheric pressure in the presenc... | 04/07/1987 |
| 4634709 | Platelet aggregation inhibitory agents and intermediates therefor This invention relates to certain heterocyclic compounds which are useful as platelet inhibitory agents and intermediates for these compounds.... | 01/06/1987 |
| 4619666 | Hair dyes containing amino-nitrobenzoic acid or amino-nitrobenzene sulfonic acids as substantive dyes Hair coloring preparations containing substantive hair dyes corresponding to the following general formula ##STR1## in which A is an SO3 H group or a COOH group, and R1 and R2 are hydrogen or other substituents, show ... | 10/28/1986 |
| 4616017 | Aminohydroxypropoxy substituted aryl compounds Novel tertiary aminohydroxypropoxy substituted aryl compounds exhibit 댑 -adrenoceptor and serotonin antagonism and are also useful as antihypertensive agents.... | 10/07/1986 |
| 4605742 | Process for the production of piperidine A process for the production of piperidine by catalytic hydrogenation of furfurylamine and/or tetrahydrofurfurylamine in the presence of a hydrogenation catalyst by flowing hydrogen gas into a reaction zone, wherein the starting material is introduced int... | 08/12/1986 |
| 4601859 | Selective hydrogenation of aliphatic dinitriles to omega-aminonitriles in ammonia with supported, finely dispersed rhodium-containing catalyst A dinitrile is hydrogenated to an omega-aminonitrile with hydrogen with a supported highly dispersed rhodium catalyst and only ammonia present. The catalyst is prepared by hydrolyzing a rhodium(III) halide or nitrate with strong aqueous base at elevated t... | 07/22/1986 |
| 4585569 | Heat pumps An absorption heat pump wherein the working fluid is a fluoroalkylamine of the formula: ##STR1## wherein each of X and X1, independently, represents hydrogen or fluorine, R represents hydrogen or a lower alkyl radical, n represents an inte... | 04/29/1986 |
