Method for lowering blood lipid levels in mammals, using certain derivatives of N-carbamoyl-2-phenylethenesulfonamide, many of which are novel....
|4062850||Thiazoloisoquinolines with coronary and respiratory effects|
1-Cyano-2-imino-2H,4H-5,6-dihydro-8,9-dimethoxy-1,2-thiazolo(3,2a)isoquinol ine or 2-imino-2H,4H-5,6-dihydro-8,9-dimethoxy-1,2-thiazolo(3,2a)isoquinoline or a pharmaceutically acceptable salt thereof. These compounds are effective as heart medicines a...
|4059586||5-Alkoxy-2-alkyl-1,2,3,4-tetrahydroisoquinolene-8-carboxaldehyde and derivatives|
Provided are novel 5-alkoxy-2-alkyl-1,2,3,4-tetrahydroisoquinolines of the formula ##STR1## wherein A is CHO--, HOOC--CH.dbd.CH--, or HOOC--CH2 --CH2 --, R and R1 are the same or different lower alkyl groups, and acid...
|4053603||Benzylisoquinoline derivatives, and use as anti-arrhythmic drugs|
Compounds of the class of benzylisoquinoline derivatives of the formula ##STR1## wherein R1 is selected from the group consisting of hydrogen and methyl, and R2 is selected from the group consisting of methyl, ethyl, n-propyl an...
|4042697||Isoquinolium compounds for treating diabetes|
Compounds of the general formula 1; ##STR1## in which R1 and R5 which may be the same or different represent an alkyl, alkenyl or alkynyl group, which groups may optionally be substituted by an amino, alkylamino or dialkylamino ...
|4035499||Imidazo (1,2-B) isoquinoline derivatives|
5,10-Dihydro-imidazo(1,2b)isoquinolines substituted in the 2- and/or 3-position(s) by an aromatic group have analgesic, anti-inflammatory or anti-pyretic activity. Except for 2-phenyl-5,10-dihydroimidazo(1,2b)isoquinoline, they are believed to be nov...
|4033756||Dichloroacetamide treated rice seeds|
Crop seed, particularly corn, grain sorghum and rice are protected from injury by a variety of herbicides particularly the thiocarbamates and some amide types by coating thereon a small, non-phytotoxic amount of an N-substituted amide of a chloro or bromo...
2-Amino-1,4-dihydropyridines bearing a carbonyl function in the 5-position and being optionally substituted by lower alkyl or phenyl in the 6-position, and the corresponding 2-amino-1,4,5,6,7,8-hexahydro-5-oxoquinolines, which derivatives are further...
|4013644||[8 (E), 13aଲ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2-phenylethen yl)-6H-dibenzo[a,g]quinolizines and intermediates thereto|
Preparation of antifungal [8(E),13aଲ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2- phenylethenyl)-6H-dibenzo[a,g]quinolizines is disclosed....
|4013666||(8,13Aଲ)-8-CARBOCYCLIC/CARBOCYCLIC METHYL-5,8,13,13A-TETRAHYDRO-2,3,10,11-TETRAMETHOXY-6H-dibenzo[a,g]quino lizines and intermediates thereto|
Preparation of antiarrhythmic and antifungal (8,13aଲ )-8-carbocyclic/carbocyclic methyl-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-6H-dibenzo[a,g]quinoli zines is disclosed....
Isoquinoline compounds having ଲ-receptor blocking activity, particularly for the heart, and having the formula ##STR1## and salts thereof with physiologically tolerable acids, wherein R1 is hydrogen or methyl, R2 is hydrog...
|4003903||N-acyl-N-norsalutaridines and process for making them|
N-acyl-N-norsalutaridines can be made by oxidative coupling of N-acyl-N-norreticulines using thallium tristrifluoroacetate or a coordinating agent and an oxidizing agent. The N-acyl-N-norsalutaridines can be converted to thebaine, N-northebaine, and ...
|4001244||1-Aryl-3,4-dihydro-2(1H)-isoquinoline carbonyl chlorides|
1-Aryl-3,4-dihydro-2(1H)-isoquinolinecarbonyl chlorides, useful in the preparation of the corresponding carboxamides, are described herein. The subject compounds can be prepared by reacting an 1-aryl-3,4-dihydro-2(1H)-isoquinoline with phosgene....
|3985881||1(3,4,5-Trimethoxybenzamido methyl) tetrahydro isoquinoline derivatives and a process for their production|
Novel isoquinoline derivatives of the formula ##SPC1## Wherein R1 is H or, together with R2, a C--N bond; R2 is H, R8 or, together with R1, a C--N bond; R3 is H, methyl or ethyl; R4
Method for lowering blood liped levels in mammals, using certain derivatives of N-carbamoyl-2-phenylethenesulfonamide, many of which are novel....
A chemiluminescent system comprising (1) derivatives of a polycarbonyl compound substituted with at least one nitrogen-containing hetero group and which may have an alkanol or amine substituent, (2) a hydroperoxide compound, (3) a diluent, and (4) a fluor...
|3969350||Base catalysis of azolesulfenamides and sulfur to aminodithioazoles|
The reaction of azolesulfenamides with sulfur to form aminodithioazoles is promoted by catalytic quantities of certain bases....
|3953458||1-Substituted amino-2-alkyl-5-hydroxy-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinoli nes|
2-Alkyl-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinolines of the formula ##SPC1## Wherein R is an aryl-lower alkyl amino group, an aryl-lower alkyl imino group, a diaryl-lower alkyl amino group or a diaryl-lower alkyl imino group, R1 is hydro...
|3953434||Dienes useful in the preparation of 1,2,3,4,4a,5,6,7-octahydro-7-aryl-isoquinolines|
Dienes of the formula ##SPC1## Wherein R1 and R2 are hydrogen, lower alkyl, lower alkenyl, aryl-lower alkyl, aryl-lower alkenyl, or heterocycle and Z is phenyl, substituted phenyl, naphthalene or heterocycle are disclosed. These ...
|3950344||Non-phenol oxidative coupling|
Oxidative coupling of non-phenolic compounds is attained by subjecting said non-phenolic compound to oxidizing conditions in contact with an oxidant selected from the group of VOF3, MoOCl4, Pb3 O4, Tl(CF3
|3947454||5 or 1'-Hydroxy-2-alkyl-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinolines and esters|
5 OR 1'-Hydroxy-2-alkyl-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinolines and esters of the formulas ##SPC1## Wherein R is a lower alkyl having 1 to 6 carbon atoms, R1 is hydrogen, a lower alkyl group, an alkanoyl, benzoyl or aralkanoyl group...
|3930837||3-Chloro-5-acetamidaisoquinoline as a herbicide|
Biologically active compositions of matter comprising substituted isoquinolines and salts thereof. Certain of the compounds and their salts are novel. Acaricidal, fungicidal, herbicidal and insecticidal activity is demonstrated. In particular 3-chloro-5-a...