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| Number | Title | Issue Date |
| 5336771 | Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines The present invention relates to processes and intermediates for the preparation of spiro-heteroazolones. The latter compounds are useful as aldose reductase inhibitors.... | 08/09/1994 |
| 5332740 | DC-89 derivatives Novel DC-89 derivatives represented by general formula (I): ##STR1## wherein X represents Cl or Br; R1 represents hydrogen, CONR2 R3 (in which R2 and R3 independently represent hydrogen, a straig... | 07/26/1994 |
| 5332814 | Process for the preparation of carbacyclic nucleosides, and intermediates Process for the preparation of racemic compounds of the formula I ##STR1## or enantiomers thereof, in which B is the radical of a nucleic base from the series comprising purine, a purine analogue or a pyridine analogue, and R is H or a protective gro... | 07/26/1994 |
| 5332715 | Plant-protecting substituted isoxazolines, isoxazoles, isothiazolines and isothiazoles, and also processes for their preparation and their use Plant-protecting substituted isoxazolines, isoxazoles, isothiazolines and isothiazoles, and also processes for their preparation and their use Compounds of the formula I (R1)(R2)(R3)Si--A--Het--B--CO--Z (I) where Het is a... | 07/26/1994 |
| 5332825 | Single vessel synthesis of aminoacetonitriles This invention relates to two processes for preparing aminoacetonitriles in one vessel under anhydrous conditions. Process I involves the steps of: (A) reacting trimethylsilyl cyanide and an aldehyde in a water miscible amide solvent to obtain a silyl blo... | 07/26/1994 |
| 5321066 | Piperdine compounds containing silane groups for use as stabilizers for organic materials The present invention relates to novel piperidine compounds of the formula (I) ##STR1## in which A is e.g. a group of the formula ##STR2## where R4 is e.g. hydrogen or methyl, X3 is e.g. --O-- or --NH-- and R5 | 06/14/1994 |
| 5314879 | Silanyl oxypropylamines endowed with antifungal activity The invention relates to the manufacture and use of aryl-propyl-aminic compounds having the following formula ##STR1## that have a high antifungal activity and are useful in the agricultural field as fungicides.... | 05/24/1994 |
| 5315006 | Method of preparing polycyclic diamines Polycyclic diamines, incorporating a basic framework similar to [3.3.3]propellane, and derivatives of the basic polycyclic diamines and a process for preparing same are provided. The diamines are prepared by subjecting bispyridine compounds to electroredu... | 05/24/1994 |
| 5310910 | Polycyclic diamines Polycyclic diamines, incorporating a basic framework similar to [3.3.3]propellane, and derivatives of the basic polycyclic diamines and a process for preparing same are provided. The diamines are prepared by subjecting bispyridine compounds to electroredu... | 05/10/1994 |
| 5304548 | Bivalent ligands effective for blocking ACAT enzyme for lowering plasma triglycerides and for elevating HDL cholesterol Bivalent ligand compounds synthesized from a tether composition joining two heterocyclic groups comprising furochromones, furobenzoxazinones, and benzobisdifurans. These compounds show pharmacological activity in blocking ACAT enzymes which are major regu... | 04/19/1994 |
| 5302589 | Heterocyclic inhibitors of 5--testosterone reductase The present invention relates to certain substituted 17 ଲ-substituted carbonyl-6-azaandrost-4-en-3-ones of formula (I): ##STR1## wherein R1 and R2 are i) independently hydrogen or lower alkyl and the bond between the carbons ... | 04/12/1994 |
| 5296480 | Angiotensin II receptor blocking 2,3,6-substituted 5,6,7,8-tetra-hydro-pyrido[4,3]pyrimidin-4(3H)-ones The invention provides compounds having the formula ##STR1## wherein R, X and R6 are defined in the specification which have activity as angiotensin II antagonists.... | 03/22/1994 |
| 5296492 | Certain chroman derivatives useful for treating symptoms caused by contraction of smooth muscles, circulatory diseases or epilepsy A chroman derivative represented by the following general formula [1]: ##STR1## wherein R1 represents cyano group, nitro group, halogenomethyl group or --SO2 --X group (X represents lower alkyl group having 1-6 carbon atoms or a... | 03/22/1994 |
| 5296484 | Quinoline derivatives The compounds of the formula: ##STR1## wherein the substituents are herein below defined; are plant fungicides, insecticides, and miticides.... | 03/22/1994 |
| 5294622 | Substituted quinolines and cinnolines The compounds of the formula: ##STR1## where the substituents are herein below defined, are fungicides, insecticides, and miticides.... | 03/15/1994 |
| 5290935 | Preparation of 2-(pyridyl)ethyl bis-(trialkyl silyl) phosphonate derivatives A process for producing phosphonate esters containing the 2-(pyridyl)ethyl group by reacting a vinylpyridine with a di- or trihydrocarbylphosphite in the presence of a selected silane, protic acid, or Lewis acid is disclosed. Also disclosed are novel sily... | 03/01/1994 |
| 5290941 | Facile condensation of methylbenzoxazoles with aromatic aldehydes An efficient process for the preparation of styrylbenzoxazoles and derivatives thereof comprises reacting a methylbenzoxazole with an aromatic aldehyde in the presence of strong base at low temperature, followed by warming. The condensation products are i... | 03/01/1994 |
| 5288730 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy Compounds of formula (I), and salts and prodrugs thereof: ##STR1## wherein Q is the residue of an optionally substituted azabicyclic ring system; X represents oxa or thia; Y represents H or hydroxy; R1 represents phenyl or thienyl, either of wh... | 02/22/1994 |
| 5286862 | Process for the preparation of aryldimethyl(3-aryl-propyl)silanes The present invention relates to a process for the preparation of compounds of the formula I ##STR1## where X is CH.dbd.CH, N.dbd.CH, CH.dbd.N or S, R1 and R2 independently of one another are H, halogen, alkyl, alkoxy, alkylthio... | 02/15/1994 |
| 5286865 | Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers 1-Hydrocarbyloxy substituted hindered amine compounds which also contain a reactive functional group such as hydroxy, amino, oxirane or carboxyl can be chemically attached to selected polymer substrates by condensation reactions to give polymers containin... | 02/15/1994 |
| 5283337 | Process for the preparation of perhaloalkylthioethers The present invention relates to a process for the preparation of perhaloalkylthioethers by bringing a perhaloalkyl halide, preferably a bromide or an iodide, into contact with a disulphide in the presence of zinc and of sulphur dioxide or of a dithionite... | 02/01/1994 |
| 5281710 | Dynemicin analogs: synthesis, methods of preparation and use A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growth-inhibiting prope... | 01/25/1994 |
| 5280033 | Substituted 1-(alkoxy-iminoalkyl) imidazole derivatives and their use in treating disease related to an enhancement of thromboxane-A2 syntheis 1-(Alkoxy-iminoalkyl)imidazole derivatives of formula ##STR1## wherein R is hydrogen or C1 -C4 alkyl; A is C1 -C4 alkylene optionally substituted by phenyl optionally substituted by halogen or trifluorometh... | 01/18/1994 |
| 5278332 | Derivatives of cyclohexane New derivatives of cyclohexane in substantially pure form suitable as pharmaceutical, foodstuff or as a stabilizer.... | 01/11/1994 |
| 5274161 | Derivatives of cyclohexane New derivatives of cyclohexane in substantially pure form suitable as a pharmaceutical, foodstuff or as a stabilizer.... | 12/28/1993 |
| 5272270 | Process for the preparation of 1-alkylisoquinoline derivatives The invention relates to a process for the preparation of 1-alkyl-1,2,3,4-tetrahydroisoquinoline derivatives of the general formula ##STR1## The compounds can be used for the preparation of tetrahydroisoquinolines of the reticuline type, or of the no... | 12/21/1993 |
| 5272162 | Platelet aggregation inhibitors This invention relates to compounds having the following formula ##STR1## or a pharmaceutically acceptable salt thereof which are useful in the inhibition of platelet aggregation, to pharmaceutical compositions including the compounds and to a method... | 12/21/1993 |
| 5264586 | Analogs of calicheamicin gamma1I, method of making and using the same Chimeric analogs of calicheamicin that include an analog of calicheamicinone linked to an ester or glycoside, (-)-calicheamicinone and its analogs are disclosed.... | 11/23/1993 |
| 5262426 | N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists A class of N,N'-cycloalkyl/alkyl benzamides of certain 4H-imidazo[4,5-b]pyridine compounds is described for treating cardiovascular and immuno-inflammatory related disorders mediated by platelet activating factor (PAF). Compounds of particular interest ar... | 11/16/1993 |
| 5258469 | Preparation of 2-(pyridyl)ethyl bis-(trialkyl silyl)phosphonate derivatives substituted phosphorous compounds A process for producing phosphonate esters containing the 2-(pyridyl)ethyl group by reacting a vinylpyridine with a di- or trihydrocarbylphosphite in the presence of a selected silane, protic acid, or Lewis acid is disclosed. Also disclosed are novel sily... | 11/02/1993 |
| 5258169 | Silicon diimide, a process for its preparation and silicon nitride obtained therefrom Silicon diimide having a carbon content of at most 0.5% by weight and a chlorine content of at most 20 ppm is prepared by reacting ammonia with organyl amino silane at 50°-300° C. at elevated pressure and is useful as an intermediate for high grade sili... | 11/02/1993 |
| 5256674 | Imidazolidine derivatives, process for producing the same and pesticides containing the same An imidazolidine derivative having the formula (I) or its salt: ##STR1## wherein X is an alkyl group which may be substituted, an alkenyl group which may be substituted, an alkynyl group which may be substituted, ##STR2## (in which each of R | 10/26/1993 |
| 5256666 | 3-Isoxazolylphenyl compounds, their preparation and their use 3-Isoxazolylphenyl compounds Ia and Ib ##STR1## where R is halogen; alkyl; haloalkyl; alkoxy; haloalkoxy; alkenyl; haloalkenyl; unsubstituted or substituted phenylethenyl; alkynyl; cycloalkyl; aryl; hetaryl; CO2 R6 or CONR7... | 10/26/1993 |
| 5254685 | Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same A tricyclic compound represented by the general formula (1) and salts thereof. ##STR1## A method for producing the tricyclic compound and salts thereof, and an antimicrobial agent containing the tricyclic compound and salts thereof as an active ... | 10/19/1993 |
| 5254563 | Beta-carbolines, process for their production and their use in pharmaceutical agents Compounds of formula I ##STR1## in which RA, B (which is CR4) and R3 and have the meaning indicated in the application, as well as their production and their use in pharmaceutical agents, are described.... | 10/19/1993 |
| 5252598 | Labdane derivatives, a process for their preparation, and their use as medicaments The present invention relates to labdane-derivatives of the formula ##STR1## a process for their preparation and the use of these substances as medicaments, preferably as medicaments having a positive ionotropic effect, an effect of lowering intraocu... | 10/12/1993 |
| 5250691 | Heteroaryl derivatives of monocyclic beta-lactam antibiotics Compounds having the formula ##STR1## exhibiting antibacterial activity.... | 10/05/1993 |
| 5246944 | Quinoline angiotensin II antagonists incorporating a substituted benzyl element Substituted quinolines and azaquinolines (1,5-naphthridines) attached through an oxymethylene bridge to novel substituted phenyl derivatives of the Formula I, are useful as angiotensin II antagonists. ##STR1##... | 09/21/1993 |
| 5246956 | N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans having antithromboxane A2 activity The invention provides new imidazole containing alkoxyimino derivatives of tetrahydronaphthalene and chroman of general formula (I) ##STR1## wherein Z is --CH2 --or--O--; m is an integer of 1 to 4; n is zero of 1; T is a straight or branched sa... | 09/21/1993 |
| 5243060 | Silylene-diethynyl-arylene polymers having liquid crystalline properties The present invention provides linear organosilicon polymers including diethynyl-(substituted)arylene units, and a process for their preparation. These novel polymers possess useful properties including electrical conductivity, liquid crystallinity, and/o... | 09/07/1993 |
