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| Number | Title | Issue Date |
| 7432257 | Piperdinyl-phenoxazine and phenothiazine derivatives as δ-opioid modulators The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic δ-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of ... | 10/07/2008 |
| 7414128 | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate The present invention relates to crystalline R-guanidines of (2S)-2-Ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate, its preparations and its use as therapeutic agents. More specifically the present invention relates to crystalline Arginine (2S)-2-Etho... | 08/19/2008 |
| 7189483 | Charge transport materials having heteroaromatic hydrazone groups An improved organophotoreceptor includes an electrically conductive substrate and a photoconductive element on the electrically conductive substrate where the photoconductive element comprises: a) a charge transport material having... | 03/13/2007 |
| 7169521 | Hydrazone-based charge transport materials Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the ... | 01/30/2007 |
| 6992082 | Phenothiazine kinesin inhibitors Phenothiazine derivatives of formula (I) are disclosed. The compounds are inhibitors of the mitotic kinesin KSP and are useful in the treatment of cellular proliferative diseases, such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and in... | 01/31/2006 |
| 6919351 | Aza-and polyaza-naphthalenyl-carboxamides useful as HIV integrase inhibitors Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or tr... | 07/19/2005 |
| 6703401 | Compounds, their preparation and use The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by clear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 03/09/2004 |
| 6608194 | Tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them A compound of Formula (Ih) ##STR1## The compounds may be used, inter alia, for preparing beta aryl-alpha-oxy substituted alkylcarboxylic acids.... | 08/19/2003 |
| 6583138 | Heterocyclic-ring condensed benzothiazine compound The invention provides a novel heterocyclic ring condensed benzothiazine compound which is effective for prevention or remedy of disease, in which histamine, leukotriene and the like participate. The heterocyclic ring condensed benzothiazine compound of t... | 06/24/2003 |
| 6548666 | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them A compound of Formula (Ig) ##STR1## The compounds may be used, inter alia, for preparing beta aryl-alpha-oxy substituted alkylcarboxylic acids.... | 04/15/2003 |
| 6444811 | Pyrazinones, compositions containing such compounds and methods of use Compounds represented by formula I: ##STR1## as well as pharmaceutically acceptable salts, esters, N-oxides and hydrates thereof are disclosed. Pharmaceutical compositions and methods of use are also included. The compounds are active against the caspase-... | 09/03/2002 |
| 6440961 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them A compound of formula (1) ##STR1## it derivatives, its analogs, its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts, or its pharmaceutically acceptable solvates, processes for its preparation and methods of use ... | 08/27/2002 |
| 6333322 | Nitrogen-containing tricyclic compounds and drugs containing the same A phenothiazine, acridan, acridone oxime, acridone hydrazone and dibenzodiazepine derivative represented by formula (I) ##STR1## effective against diseases in which histamine, leukotrienes, etc. participate and effective in preventing or treating diseases... | 12/25/2001 |
| 6159966 | Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them A compound of formula (I) ##STR1## its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates, wherein R3, R4, R5, and R6 are ... | 12/12/2000 |
| 6139876 | Gel with increased oxygen content A gelatin with increased oxygen content for pharmaceutical, cosmetic and/or veterinary use. The gelatin comprises a gelling agent and a solvent, furthermore oxygen in a substantially even distribution with a pressure exceeding normal atmospheric pressure,... | 10/31/2000 |
| 6054453 | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them Novel ଲ-aryl--oxysubstituted alkylcarboxylic acids of the formula (I) and compositions containing them. ##STR1## The compounds have hypolipidemic, antihyperglycemic uses.... | 04/25/2000 |
| 5597819 | Phenothiazine cytokine inhibitors New benzothiazine derivatives corresponding to the general formula I: ##STR1## in which: X represents halogen, n represents 0, 1, or 2, B represents the following formula: ##STR2## in which: R1 & R2 together with the carbons to ... | 01/28/1997 |
| 5321026 | Phenothiazine derivatives, their preparation and pharmaceutical compositions containing them New phenothiazine derivatives of general formula (I) in which R represents 4- to 6-membered cycloalkyl, or represents --CH2 R" in which R" is hydrogen, alkyl containing 1 to 5 carbon atoms, alkenyl or alkynyl containing 2 to 4 carbon atoms, cycloalk... | 06/14/1994 |
| 5049669 | Analgesic phenothiazine derivatives Phenothiazine derivatives of general formula (I), in which R is a linear or branched (1 to 6 C) alkyl radical and R1 and R2, which may be identical or different, are linear or branched (1 to 4 C) alkyl radicals or form, with the nitr... | 09/17/1991 |
| 5024774 | Nitrogen containing anti-oxidant compositions This invention describes compositions containing nitrogen, sulfur and optionally oxygen which are useful as antioxidants for lubricants.... | 06/18/1991 |
| 4985419 | Phenothiazine derivatives, their preparation and pharmaceutical compositions containing them Phenothiazine derivatives of formula: ##STR1## in which Y is hydrogen or halogen, R1 and R2, which may be identical or different, denote alkyl, cycloalkyl-alkyl, hydroxyalkyl or acetyloxyalkyl radicals or form, together with the... | 01/15/1991 |
| 4912105 | Derivatives of phenothiazine and the compositions which contain them Phenothiazine derivatives of formula ##STR1## in which R represents --NR1 R2 in which R1 and R2, which may be identical or different, are alkyl, hydroxyalkyl or acetyloxyalkyl radicals, or form, together wi... | 03/27/1990 |
| 4888335 | 3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents Propylamines of the formula (I): ##STR1## and isomers thereof, particularly those enantiomers and racemates relative to the chiral carbon indicated by an asterisk (*). The propylamines can be used for the treatment of hypertension or angina in humans... | 12/19/1989 |
| 4798684 | Nitrogen containing anti-oxidant compositions This invention describes compositions containing nitrogen, sulfur and optionally oxygen which are useful as antioxidants for lubricants.... | 01/17/1989 |
| 4727151 | Labile quaternary ammonium salts as prodrugs Labile quaternary ammonium salts of the following formula (I) and (II) are provided: ##STR1## wherein N represents a tertiary aliphatic amine; wherein N represents an unsaturated amine; wherein R represents a member selected from the group con... | 02/23/1988 |
| 4705854 | Phenothiazine compounds The present invention relates to compounds of the formula (I): ##STR1## or a salt, ester or amide thereof; wherein R1 is a C1-7 bivalent aliphatic hydrocarbon group or a single bond; R2 and R3 are the same or di... | 11/10/1987 |
| 4628087 | Process for the preparation of pharmacologically active compounds containing a sulfoxide group Process for the preparation of pharmacologically active compounds containing a sulfoxide group by oxidation of a thioether with hypochlorite in an alkaline medium at a pH higher than 10 and at a temperature comprised between 0° and 40° C.... | 12/09/1986 |
| 4482711 | Process for the preparation of N,N-dimethyl-10-[1-aza-[2,2,2]-bicyclo-3-octyl]-10H-2-phenothiazine sulphonamide Process for the preparation of N,N-dimethyl-10[1-aza-[2,2,2]-bicyclo-3-octyl]-10H-2-phenothiazine sulphonamide, usable as a gastric secretion inhibitor, characterized in that N,N-dimethyl-3-[(1-aza-[2,2,2]-bicyclo-3-octyl)amino]-4-[(2-bromophenyl)th ... | 11/13/1984 |
| 4451461 | 10-(1-Aza-[2,2,2)-bicyclo-3-octyl]-10H-2-phenothiazinesulfonamide and derivatives thereof 10-[1-aza-(2,2,2)-bicyclo-3-octyl]-10H-2-phenothiazinesulfonamides of the formula: ##STR1## wherein R represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms are disclosed together with a process for their preparation. These comp... | 05/29/1984 |
| 4435393 | Derivatives of 10-(1-azabicyclo[2.2.2]oct-3-yl)-N,N dimethyl-10H-phenothiazine-2-sulfonamide as medicaments Compounds of the general formula: ##STR1## in which either X represents an atom of sulfur and Y represents the N-oxide group or X represents the sulfinyl group or the sulfonyl group and Y represents an atom of nitrogen or the N-oxide group and their ... | 03/06/1984 |
| 4246404 | Basic indoline dyestuffs Basic dyestuffs free of sulphonic acid groups contain an indoline group the 2-position of which is connected through a vinylene group to the N-atom of a 2,3-dihydro-4H-1,4-benzoxazine group. The dyestuffs are useful for the dyeing of leather, paper and pl... | 01/20/1981 |
| 4160099 | Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives Labile quaternary ammonium salts of the following formula (I) and (II) are provided: ##STR1## wherein ##STR2## represents a tertiary aliphatic amine; wherein ##STR3## represents an unsaturated amine; wherein R represents a member selec... | 07/03/1979 |
| 4153694 | Behenic acid esters, compositions thereof and a method of preparation thereof The present invention relates to novel behenic acid esters of the following general formula: ##STR1## wherein X is "N" or "CH," the non-toxic acid addition salts thereof, a method for the preparation of said esters and therapeutic compositions t... | 05/08/1979 |
| 4065471 | N-(4-Amino-2-butynyl)imides N-(4-Amino-2-butynyl)imides are prepared from N-propargylimides, paraformaldehyde and the appropriate secondary amine. The compounds are useful as stimulants or depressants of the central nervous system.... | 12/27/1977 |
| 3975379 | Dihydroindoles and indolenine dyestuffs Dihydroindoles of the formula ##SPC1## And their use as coupling or condensation components for the manufacture of basic indolenine dyestuffs of the formula ##SPC2## The dyestuffs are used for dyeing and printing natural are used for dyeing and print... | 08/17/1976 |
