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Class 544/41 - Nitrogen containing substituent bonded to nitrogen of phenothiazine ring system


Subclass of Class 544 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein a nitrogen containing substituent is bonded
No. of patents: 37
Last issue date: 06/10/2008


NumberTitleIssue Date
7384933Derivatives of 2-hydroxytetrahydrofuran and their use as medicaments
A hydroxytetrahydrofuran of formula wherein A is with the substituents as defined in the specification, having a calpain inhibiting activity and/or an activity which traps the rea...
06/10/2008
7358358Electrochromic compound
A compound for use in electrochromic devices. The compound includes (1) β-(10-phenothiazyl)propoxy phosphonic acid; (2) β-(10-phenothiazyl)propyl-phosphonic acid; and (3) β-(10-phenothiazyl)propionate phosphonic acid. ...
04/15/2008
7160874Phenylalanine derivatives
Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin. ...
01/09/2007
7083884Organophotoreceptor with charge transport material having a hydrazone group linked to an epoxy group and a heterocyclic ring
Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the ...
08/01/2006
6992082Phenothiazine kinesin inhibitors
Phenothiazine derivatives of formula (I) are disclosed. The compounds are inhibitors of the mitotic kinesin KSP and are useful in the treatment of cellular proliferative diseases, such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and in...
01/31/2006
6855706Phenylalanine derivatives
Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α 4 integrin. They are used as therapeutic agents for various diseases concerning α 4 integrin. ...
02/15/2005
6800618Chemosensitizing agents against chloroquine resistant plasmodium falciparum and methods of making and using thereof
A compound having the structural formula or a pharmaceutically acceptable salt or prodrug thereof, wherein X is a substituted or unsubstituted alkyl or a heteroatom; n is 4, 5 or 6; Y is a substituted or unsubstituted al...
10/05/2004
6583138Heterocyclic-ring condensed benzothiazine compound
The invention provides a novel heterocyclic ring condensed benzothiazine compound which is effective for prevention or remedy of disease, in which histamine, leukotriene and the like participate. The heterocyclic ring condensed benzothiazine compound of t...
06/24/2003
6365586Compounds, their preparation and use
The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR)....
04/02/2002
6333322Nitrogen-containing tricyclic compounds and drugs containing the same
A phenothiazine, acridan, acridone oxime, acridone hydrazone and dibenzodiazepine derivative represented by formula (I) ##STR1## effective against diseases in which histamine, leukotrienes, etc. participate and effective in preventing or treating diseases...
12/25/2001
6083651Phenothiazine or phenoxazine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor
A phenothiazine or phenoxazine derivative represented by the following general formula (1), a charge-transporting material comprising the derivative, and an electrophotographic photoreceptor containing the charge-transporting material are disclosed. The c...
07/04/2000
5942615Phenothiazine or phenoxazine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor
A phenothiazine or phenoxazine derivative represented by the following general formula (1), a charge-transporting material comprising the derivative, and an electrophotographic photoreceptor containing the charge-transporting material are disclosed. The c...
08/24/1999
5861394Use of N-substituted phenothiazines
The invention relates to the use of N-substituted phenothiazines for the production of medicaments for the treatment of cerebral disorders. The invention likewise relates to novel active compounds which are prepared by reaction of phenothiazine with the a...
01/19/1999
5597819Phenothiazine cytokine inhibitors
New benzothiazine derivatives corresponding to the general formula I: ##STR1## in which: X represents halogen, n represents 0, 1, or 2, B represents the following formula: ##STR2## in which: R1 & R2 together with the carbons to ...
01/28/1997
5321026Phenothiazine derivatives, their preparation and pharmaceutical compositions containing them
New phenothiazine derivatives of general formula (I) in which R represents 4- to 6-membered cycloalkyl, or represents --CH2 R" in which R" is hydrogen, alkyl containing 1 to 5 carbon atoms, alkenyl or alkynyl containing 2 to 4 carbon atoms, cycloalk...
06/14/1994
5308840Substituted or unsubstituted benzhydryl heteroalkyl-substituted aminophenol compounds and pharmaceutical compositions thereof
Aminophenol derivatives of the following formula (I) ##STR1## wherein X is hydrogen atom, lower alkyl or a protecting group for phenolic hydroxy, Y is hydrogen atom or lower alkyl, Z is hydrogen atom, lower alkyl, halogen atom or trifluoromethyl, A i...
05/03/1994
5269954Nitrogenous additives with an antioxidant action and lubricating compositions containing the said additives
The present invention relates to the preparation of antioxidant additives to lubricants and to their use in lubricating compositions. The additives according to the invention have the formula: ArAr'(H)N--(R--X)a --R'Y where--Ar and Ar' are identical...
12/14/1993
5049669Analgesic phenothiazine derivatives
Phenothiazine derivatives of general formula (I), in which R is a linear or branched (1 to 6 C) alkyl radical and R1 and R2, which may be identical or different, are linear or branched (1 to 4 C) alkyl radicals or form, with the nitr...
09/17/1991
5024774Nitrogen containing anti-oxidant compositions
This invention describes compositions containing nitrogen, sulfur and optionally oxygen which are useful as antioxidants for lubricants....
06/18/1991
4985419Phenothiazine derivatives, their preparation and pharmaceutical compositions containing them
Phenothiazine derivatives of formula: ##STR1## in which Y is hydrogen or halogen, R1 and R2, which may be identical or different, denote alkyl, cycloalkyl-alkyl, hydroxyalkyl or acetyloxyalkyl radicals or form, together with the...
01/15/1991
4912105Derivatives of phenothiazine and the compositions which contain them
Phenothiazine derivatives of formula ##STR1## in which R represents --NR1 R2 in which R1 and R2, which may be identical or different, are alkyl, hydroxyalkyl or acetyloxyalkyl radicals, or form, together wi...
03/27/1990
4798684Nitrogen containing anti-oxidant compositions
This invention describes compositions containing nitrogen, sulfur and optionally oxygen which are useful as antioxidants for lubricants....
01/17/1989
4798895Process for preparing levomepromazine hydrogen maleate
Levomepromazine hydrogen maleate is prepared by resolving (&#b1;)-10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine with (-)-di(p-toluoyl)-L-tartaric acid to produce the neutral salt of the dextrorotatory base and then adding maleic acid to the m...
01/17/1989
4705854Phenothiazine compounds
The present invention relates to compounds of the formula (I): ##STR1## or a salt, ester or amide thereof; wherein R1 is a C1-7 bivalent aliphatic hydrocarbon group or a single bond; R2 and R3 are the same or di...
11/10/1987
4681878Fluoropheno-thiazine and pharmaceutical use
The compound 2-[10-(2-Dimethylaminopropyl)-7-fluoro-2-phenothiazinyl]-2-methylpropionic acid or a pharmaceutically acceptable salt thereof. The compound or salt are useful as antihistamines....
07/21/1987
4634699Branched chain phenothiazine
The compound 2-[10-(2-Dimethylaminopropyl)-2-phenothiazinyl]-2-methylpropionic acid or a pharmaceutically acceptable salt thereof. The compound and salt are useful as antihistamines....
01/06/1987
4628087Process for the preparation of pharmacologically active compounds containing a sulfoxide group
Process for the preparation of pharmacologically active compounds containing a sulfoxide group by oxidation of a thioether with hypochlorite in an alkaline medium at a pH higher than 10 and at a temperature comprised between 0° and 40° C....
12/09/1986
4366314Dimethine dyestuffs, their preparation and their use for dyeing synthetic and natural materials
Styryl dyestuffs of the general formula ##STR1## wherein Het represents a pyridinium radical having the structure ##STR2## R and R1 independently of one another designate lower alkyl or alkenyl groups, which can be substituted by non-...
12/28/1982
4349679Pyrrolidino and piperidino benz ring substituted phthalides
Phthalide compounds of the formula ##STR1## wherein A and B, independently of the other, represent a monovalent radical of the formula ##STR2## wherein X1 represents an amino group of the formula ##STR3## X2 repre...
09/14/1982
4258182Quaternized amino-substituted styryl dyestuffs
Styryl dyestuffs of the formula ##STR1## wherein Q.sym. represents a grouping containing a quaternary nitrogen atom and A represents a bridge member, at least one of the radicals R and R1 denotes a carbocyclic or heterocyclic 5-membered or...
03/24/1981
4160099Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives
Labile quaternary ammonium salts of the following formula (I) and (II) are provided: ##STR1## wherein ##STR2## represents a tertiary aliphatic amine; wherein ##STR3## represents an unsaturated amine; wherein R represents a member selec...
07/03/1979
4155874Phenothiazinyl sulfides
A new group of compounds, generically classed as phenothiazinyl sulfides, are described having the formula: ##STR1## wherein n is 1 or 2, x and/or y and/or z represent 0, 1 or 2; R1 may be H, alkyl, aryl, alkaryl, acyl, haloacyl and biolog...
05/22/1979
4122186Acetohydroxamic acids
The invention provides new acetohydroxamic acid derivatives, having interesting properties on the central nervous system, of the formula: R1 R2 R3 C-CO-NHOH, in which R2 and R3 are each hydrogen or C
10/24/1978
4065471N-(4-Amino-2-butynyl)imides
N-(4-Amino-2-butynyl)imides are prepared from N-propargylimides, paraformaldehyde and the appropriate secondary amine. The compounds are useful as stimulants or depressants of the central nervous system....
12/27/1977
4029783N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them
New N-substituted 1-amino-3-phenoxy-propan-2-ol compounds of the formula: ##STR1## wherein R1 and R2 are, individually, hydrogen or, taken together, represent a sulfur linkage, an ethylene radical or a valency bond; B is straigh...
06/14/1977
3998810N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them
New N-substituted 1-amino-3-phenoxy-propan-2-ol compounds of the formula: ##EQU1## wherein R1 and R2 are, individually, hydrogen or, taken together, represent a sulfur linkage, an ethylene radical or a valency bond; B is straigh...
12/21/1976
3966930Phenothiazine derivatives, compositions thereof and methods of preparation thereof
Fluoro-substituted phenothiazine derivatives as well as their non-toxic pharmaceutically acceptable acid addition salts having pronounced neuroleptic properties and a relatively low degree of undesired side effects, a method for the preparation of said de...
06/29/1976
 
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