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| Number | Title | Issue Date |
| 5554641 | Nonpeptides as tachykinin antagonists The small nonpeptides of the instant invention are tachykinin antagonists. The compounds are highly selective and functional NK3 antagonists expected to be useful in the treatment of pain, depression, anxiety, panic, schizophrenia, neuralgia, a... | 09/10/1996 |
| 5554793 | Catalytic reforming of alkyleneamines A process of reforming an alkyleneamine feedstock or a mixture of such feedstocks to an alkyleneamine or a mixture of alkyleneamines which is different from the feedstock or feedstock mixture. The process is catalyzed by one of the following: Group VB met... | 09/10/1996 |
| 5516913 | Alcohols Novel alcohols of the formula ##STR1## wherein Ra is azido or phthalimido, R4 is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, R7 and R8 together are a trimethylene or tetramethylene group which is o... | 05/14/1996 |
| 5491263 | Aminoethylation process for production of substituted ethylene diamines A process is disclosed for producing a substituted ethylenediamine, the process comprising reacting an oxazolidinone with a secondary amine or an alkanolamine. The process includes, in one aspect, reacting precursors of the oxazolidinone in situ.... | 02/13/1996 |
| 5451678 | Alcohols Novel alcohols of the formula ##STR1## wherein Ra is azido or phthalimido, R4 is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, R7 and R8 together are a trimethylene or tetramethylene group which is o... | 09/19/1995 |
| 5410087 | Catalytic reforming of alkyleneamines A process of reforming an alkyleneamine feedstock or a mixture of such feedstocks to an alkyleneamine or a mixture of alkyleneamines which is different from the feedstock or feedstock mixture. The process is catalyzed by one of the following: Group VB met... | 04/25/1995 |
| 5410086 | Selective preparation of diethylenetriamine This invention relates to a method for controlling the weight ratio of diethylenetriamine to piperazine in a process in which ethylenediamine, or a mixture of ethylenediamine and monoethanolamine, and hydrogen are maintained in the presence of a hydrogena... | 04/25/1995 |
| 5389630 | Diamine compound and brain protecting agent containing the same Diamine compounds of formula (I) or an addition salt thereof are provided: ##STR1## These compounds have an excellent cerebral protective action, are very safe, and exhibit a strong action when orally administered, and therefore, medicines containing... | 02/14/1995 |
| 5371088 | 1-aryl-4-piperazinylcyclohexanecarbonitriles, the preparation and use thereof Compounds of the formula ##STR1## where Ar, R1, R2, P and Q have the meanings indicated in the description, and the preparation thereof are described. The compounds have antihypoxic and antiischemic action and are suitable for t... | 12/06/1994 |
| 5356895 | 1,4 piperizino inhibitors of non-enzymatic cross-linking of proteins The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises; an agent capable of inhibiting the formation of advanced glycosylation endproduct... | 10/18/1994 |
| 5332816 | Piperazine-piperidine compounds for use as stabilizers for organic materials The present invention relates to novel piperazine-piperidine compounds of the general formula (I) ##STR1## in which R1 is e.g. hydrogen or methyl, R2 is e.g. ethylene, m is zero or 1 and n is e.g. 1, and when n is 1, A is e.g. ... | 07/26/1994 |
| 5326762 | Inhibitors of acyl-coenzyme A: cholesterol acyl transferase Amides of the formula ##STR1## wherein R1 and R2 are independently heteroaryl, X-substituted heteroaryl, X-substituted phenyl, N-substituted triazinyl or N-substituted imidazolyl; and in addition, one of R1 and R... | 07/05/1994 |
| 5321160 | Process for producing an ethylenamine A process for producing an ethylenamine, which comprises reacting ammonia and/or an ethylenamine with an ethanolamine in the presence of hydrogen to obtain an ethylenamine having an increased number of ethylene chains over the ammonia and/or the ethylenam... | 06/14/1994 |
| 5318970 | Isoxazole compounds, pharmaceutically acceptable salts thereof and medical uses thereof A isoxazole compound represented by the formula (1): ##STR1## wherein R represents a hydrogen atom or a lower alkoxy group, R1 is a group represented by the formula (2): ##STR2## (wherein A represents --NH-- or --O--, B represents a m... | 06/07/1994 |
| 5302720 | Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents Compounds of formula I ##STR1## and their salts in which R1 is optionally substituted phenyl, R2 is alkyl, cycloalkyl or optionally substituted amino, or R2 and R3 together with the nitrogen and carbon atom... | 04/12/1994 |
| 5296633 | HMTA preparation of methylated tertiary amines The methylated tertiary amines are selectively prepared by reacting a primary or secondary amine, or a nitrile or aminonitrile, including an aminoalcohol, etheramine, a polyamine or fatty polyamine or amidoamine, or amidopolyamine or dinitrile, with hexam... | 03/22/1994 |
| 5296154 | High molecular weight nitrogen-containing condensates and fuels and lubricants containing same Improved additives/detergents for lubricant and fuel compositions are obtained by condensing a hydroxyalkyl or hydroxyaryl compound with an amine compound. The condensates according to the present invention are produced by the acid catalyzed condensation ... | 03/22/1994 |
| 5288909 | Catalytic reforming of alkyleneamines A process of reforming an alkyleneamine feedstock or a mixture of such feedstocks to an alkyleneamine or a mixture of alkyleneamines which is different from the feedstock or feedstock mixture. The process is catalyzed by one of the following: Group VB met... | 02/22/1994 |
| 5262535 | Surfactant composition and method of making the same The reaction product of: (a) a compound of the formula: ##STR1## wherein X is a member selected from the group consisting of N, O and S; R1 and R2 are independently a straight or branched, saturated or unsaturated non-aromatic ... | 11/16/1993 |
| 5262534 | Process for the preparation of nonaromatic cyclic nitrogen-containing compounds A process for preparing nonaromatic N,N,N-trisubstituted nitrogen-containing compounds which comprises heating a nonaromatic carboxylated N,N,N-trisubstituted nitrogen-containing compound at an elevated temperature for a period of time sufficient to produ... | 11/16/1993 |
| 5256786 | Catalytic reforming of cyclic alkyleneamines A process of reforming cyclic alkyleneamines to amine-extended cyclic alkyleneamines involving contacting a cyclic alkyleneamine or mixture of cyclic alkyleneamines in the liquid phase with a catalyst under reaction conditions. The catalyst is selected fr... | 10/26/1993 |
| 5254689 | Piperdinyl and piperazinyl derivatives Compounds of the formula: ##STR1## in which R1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2, --CN, 1-imidazolyl or 1,2,4-triazol-1-yl; Y is ##STR2## --CH2 --, -... | 10/19/1993 |
| 5245032 | Catalytic processes for the preparation of N,N,N-trisubstituted nitrogen-containing compounds A process for preparing N,N,N-trisubstituted nitrogen-containing compounds which comprises contacting a carboxylated N,N,N-trisubstituted nitrogen-containing compound with a mixed metal oxide catalyst under conditions effective to produce the N,N,N-trisub... | 09/14/1993 |
| 5231230 | Selective production of diethylenetriamine This invention relates to a process for making amines having a high yield weight percent of diethylenetriamine (DETA) by condensing an amino compound in the presence of a condensation catalyst selected from a Group IVB metal oxide, a metallic phosphate ha... | 07/27/1993 |
| 5227528 | Decolorization of polyalkylene polyamines A process for decolorizing polyalkylene polyamines, which comprises contacting one or more polyalkylene polyamines having an average molecular weight of greater than about 200 and less than about 1000 with carbon at a temperature greater than or equal to ... | 07/13/1993 |
| 5225599 | Selective production of linear triethylenetetramine and aminoethylethanolamine This invention relates to a process for making amines having a high yield weight percent of linear triethylenetetramine (L-TETA) and aminoethylethanolamine (AEEA) by condensing an amino compound in the presence of a condensation catalyst selected from a G... | 07/06/1993 |
| 5225600 | Amines catalysis using group VIB metal-containing condensation catalysts This invention relates to a process for making amines by condensing an amino compound in the presence of a Group VIB metal-containing condensation catalyst. This invention also relates to an alkyleneamines producers composition rich in triethylenetetramin... | 07/06/1993 |
| 5225598 | Selective production of linear pentaethylenehexamine and hydroxyethyldiethylenetriamine This invention relates to a process for making amines having a high yield weight percent of linear pentaethylenehexamine (L-PEHA) and hydroxyethyldiethylenetriamine (HEDETA) by condensing an amino compound in the presence of a condensation catalyst select... | 07/06/1993 |
| 5223498 | Phenylamidine and phenylguanidine derivatives and their use as antidiabetic agents Compounds of formula I ##STR1## and their salts in which n=0 or 1, R1 and R2 are each aliphatic or cycloalkyl or NR1 R2 is an optionally substituted heterocyclic ring, R3 is alkyl, cycloalkyl or ... | 06/29/1993 |
| 5220071 | Selective production of pentaethylenehexamine and hydroxyethyltriethylenetetramine This invention relates to a process for making amines having a high yield weight percent of pentaethylenehexamine (PEHA) and hydroxyethyltriethylenetetramine (HETETA) by condensing an amino compound in the presence of a condensation catalyst selected from... | 06/15/1993 |
| 5215989 | Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents Compounds of structural formula: ##STR1## wherein Ar is an aromatic ring, B is a cyclic moiety fused to Ar of 5-7 members, X and Y are bridging groups, Q is a nitrogen containing heterocycle, R2 and R3 are H, substituted or unsu... | 06/01/1993 |
| 5214215 | Selective production of aminoethylethanolamine This invention relates to a process for making amines having a high yield weight percent of aminoethylethanolamine (AEEA) by condensing an amino compound in the presence of a condensation catalyst selected from a Group IVB metal oxide, a Group VIB metal-c... | 05/25/1993 |
| 5214213 | Selective production of linear tetraethylenepentamine and hydroxyethyldiethylenetriamine This invention relates to a process for making amines having a high yield weight percent of linear tetraethylenepentamine (L-TEPA) and hydroxyethyldiethylenetriamine (HEDETA) by condensing an amino compound in the presence of a condensation catalyst selec... | 05/25/1993 |
| 5210307 | Catalytic reforming of alkyleneamines to linearly-extended polyalkylenepolyamines A process for reforming alkyleneamines to predominantly linearly-extended polyalkylenepolyamines comprising contacting an alkyleneamine or mixture thereof with a catalyst under conditions such that a mixture of polyalkylenepolyamines enriched in linearly-... | 05/11/1993 |
| 5210306 | Promoted amines catalysis This invention relates to a process for making amines by condensing an amino compound in the presence of a condensation catalyst and a condensation catalyst promoter, wherein said condensation catalyst promoter is present in an amount sufficient to promot... | 05/11/1993 |
| 5210193 | Piperazine derivatives 7-(substituted)piperazinyl-1-ethyl-6-fluoro-4-oxo-3-quinolinecarboxylic acids, the pharmacologically acceptable salts thereof, compositions containing them, processes and intermediates for producing them, and methods of using them to treat bacterial infec... | 05/11/1993 |
| 5202491 | Process for the manufacture of diethylenetriamine A continuously generated alkyleneamines producers composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present, a) about 20 to about 40 mole % DETA, b) about 15 to about 60 mole % EDA (net generated), c) abou... | 04/13/1993 |
| 5202490 | Process for thr manufacture of diethylenetriamine and aminoethylethanolamine A continuously generated alkyleneamines producers composition comprising based on 100% of the moles of the compostion and exclusive of any MEA and water present, a) about 15 to about 35 mole % DETA, b) about 15 to about 55 mole % EDA (net generated), c) about ... | 04/13/1993 |
| 5200520 | Process for the production of piperazinylpyrimidine derivatives A process for the production of piperazinylpyrimidine derivatives of the formula I: ##STR1## wherein R1 is a hydrogen atom or a C1 -C4 alkyl group, branched or unbranched. In the process, piperazine or its hydrate is ... | 04/06/1993 |
| 5196588 | Ethylenediamine and diethylenetriamine producers composition and method for producing same A continuously generated alkyleneamines producers composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present, a) about 14 to about 20 mole % DETA, b) about 45 to about 75 mole % EDA (net generated), c) abou... | 03/23/1993 |
