Bizarre Patents
User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 7439245 | Compounds Disclosed is a method for use of phenyl sulfone compounds of formula (I) in the treatment of anxiety. ... | 10/21/2008 |
| 7417043 | Modulators of dopamine neurotransmission A 3-substituted 4-(phenyl-N-alkyl)-piperazine compound of the following formula: wherein R1 is selected from the group consisting of OSO2CF3, OSO2CH3, SO2R | 08/26/2008 |
| 7410971 | 1,2-di(cyclic)substituted benzene compounds A compound represented by the following general formula (1) or (100), a salt thereof or a hydrate of the foregoing has excellent cell adhesion inhibitory action or cell infiltration inhibitory action, and is useful as a therapeutic or prophylactic agent for various ... | 08/12/2008 |
| 7381728 | Piperazine derivatives useful for the treatment of gastrointestinal disorders The invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Re, Rf and Y are as defined in the specification. The compounds are partial or ful... | 06/03/2008 |
| 7262188 | Phenyl sulfone derivatives and their use in the treatment of CNS disorders This invention relates to novel phenyl sulfone compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders. ... | 08/28/2007 |
| 7226925 | Compounds, their use and preparation The invention relates to compounds of the general Formula (I): The compounds may be prepared by per se conventional methods and can be used for treating a human or animal subject suffering from a serotonin-related ... | 06/05/2007 |
| 7173035 | Arylsulfonamide compounds The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II... | 02/06/2007 |
| 7148238 | Phenyl-piperazine derivatives as serotonin reuptake inhibitors The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depress... | 12/12/2006 |
| 7144884 | Phenyl-piperazine derivatives as serotonin reuptake inhibitors The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disor... | 12/05/2006 |
| 7138407 | Phenyl-piperazine derivatives as serotonin reuptake inhibitors The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depress... | 11/21/2006 |
| 7037914 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I) (wherein all symbols are as defined in the specification), a non-toxic acid thereof or a hydrate thereof as ... | 05/02/2006 |
| 6903120 | Modulators of dopamine neurotransmission New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)-piperidine compounds of Formula (1), wherein X N, CH, or C, however X may only be C when the compound comprises a double bond at the dotted line; R1 is OSO2CF3, O... | 06/07/2005 |
| 6825202 | Arylsulfonyl derivatives with 5-HT6 receptor affinity This invention relates to compounds which have generally 5-HT6 receptor affinity and which are represented by Formula (I): wherein Ar, R1, R2, R3 or R4 are as defined in the ... | 11/30/2004 |
| 6762300 | Method for producing 5-(1-piperazinyl)-benzofuran-2-carboxamide by transition metal-catalyzed amination Process for the preparation of 5-(1-piperazinyl)benzofuran-2-carboxamide in which, as intermediate step, 5-bromosalicylaldehyde or one of its derivatives is reacted in a transition metal-catalysed amination with R2-piperazine, in which R2 is as... | 07/13/2004 |
| 6753429 | 1,4-disubstituted benzenes as insecticides Compounds of formula I: wherein A, B, D, and R are as defined herein and their agriculturally acceptable salts are disclosed as effective insecticides. In addition, compositions comprising an insecticidally effective amo... | 06/22/2004 |
| 6727257 | 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines This invention is directed to dihydropyrimidine compounds of the following formula: wherein A is which are selective antagonists for human α1C receptors. This inv... | 04/27/2004 |
| 6673799 | Cyanophenyl derivative This application relates to a piperazino-substituted novel cyanophenyl derivative in which a substituted carbamoyl or substituted sulfamoyl group having an aryl, heterocyclic or the like group that may have a substituent group is bonded to one nitrogen at... | 01/06/2004 |
| 6608195 | Process for the preparation of 2-(4-alkyl-1-piperazinyl)-benzaldehyde and -benzylidenyl compounds The present invention relates to a novel process for the preparation of a compound of formula I: ##STR1## wherein R1 is defined herein and compounds of formula II: ##STR2## wherein R1 and R2 are defined herein. Said compou... | 08/19/2003 |
| 6579870 | Bis-arylsulfones The present invention provides pharmaceutically active compounds useful for the treatment of diseases or disorders of the central nervous system.... | 06/17/2003 |
| 6525099 | N-substituted sulfonamide derivatives The present invention provides certain N-substituted sulfonamide derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.... | 02/25/2003 |
| 6525199 | Arylpiperidinopropanol and arylpiperazinopropanol derivatives and pharmaceuticals containing the same A compound having the formula (I) or its salt, hydrate, hydrate salt or solvate: ##STR1## wherein R1 to R4 independently represent H, halogen, OH, alkoxy, optionally substituted alkyl, aryl, or aralkyl group, R5 represents... | 02/25/2003 |
| 6423717 | Sulphonamide derivatives, process for their preparation, and their use as medicaments Novel sulphonamide derivatives having CNS activity, processes for their preparation and their use as medicaments are disclosed. The present compounds are of formula (I) or a salt thereof: ##STR1## wherein: P isbenzothiophene, benzothiadiazole, quinoline, ... | 07/23/2002 |
| 6410530 | Substituted 1,2,3,4-tetrahydronaphthalene derivatives New piperidinyl- or piperazinyl-substituted-1,2,3,4-tetrahydronaphthalene derivatives having the formula ##STR1## wherein X is N or CH; Y is NR2 CH2, CH2 --NR2, NR2 --CO, CO--NR2 or NR... | 06/25/2002 |
| 6407099 | Arylpiperidinopropanol and arylpiperazinopropanol derivatives and pharmaceuticals containing the same A compound having the formula (I) or its salt, hydrate, hydrate salt or solvate: ##STR1## wherein R1 to R4 independently represent H, halogen, OH, alkoxy, optionally substituted alkyl, aryl, or aralkyl group, R5 represents... | 06/18/2002 |
| 6316450 | Compounds The invention relates to novel compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS disorders.... | 11/13/2001 |
| 6313118 | Substituted 1,2,3,4-tetrahydronaphthalene derivatives The present invention relates to new piperidyl- or piperazinyl-substituted-1,2,3,4-tetrahydronaphthalene derivatives having the formula I ##STR1## wherein X is N or CH; Y is NR2 CH2, CH2 --NR2, NR2 --... | 11/06/2001 |
| 6245767 | Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof A monohydrate of an aminobenzenesulfonic acid derivative represented by the following formula (I), for example, 2-(1-piperazinyl)-5-methylbenzenesulfonic acid, is substantially free from weight change due to moisture absorption and can be weighed accurate... | 06/12/2001 |
| 6218394 | 4-Aryl-1-(indanmethyl, dihydrobenzofuranmethyl or dihydrobenzothiophene-methyl) piperazines 4-Aryl-1-(indanmethyl, dihydrobenzofuramethyl or dihydrobenzothiophenemethyl) piperidine, -tetrahydropyridine or -piperazine compounds of general formula (I) ##STR1## wherein one of X and Y is CH2, and the other one is CH2, O or S; ... | 04/17/2001 |
| 6166020 | Aryl and heteroaryl alkoxynaphthalene derivatives Compounds of the formula ##STR1## wherein R1, R2, R4, R23, R24, R25 and R26 are defined as in the specification. These compounds are useful psychotherapeutics and are potent sero... | 12/26/2000 |
| 6107508 | Convergent synthesis of -aryl-ଲ-ketonitriles The present invention relates to processes for the production of -aryl-ଲ-ketonitriles, which serve as synthetic intermediates in the preparation of a series of biologically important molecules such as corticotropin releasing factor (CRF) rece... | 08/22/2000 |
| 6001835 | Inhibitors of farnesyl-protein transferase The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invent... | 12/14/1999 |
| 5990113 | Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof A monohydrate of an aminobenzenesulfonic acid derivative represented by the following formula (I), for example, 2-(1-piperazinyl)-5-methylbenzenesulfonic acid, is substantially free from weight change due to moisture absorption and can be weighed accurate... | 11/23/1999 |
| 5977357 | Phenyl alkyl ketone substituted by cyclic amine and a process for the preparation thereof A novel process for the preparation of compounds of formula I ##STR1## by aminolysis of a p-halophenyl alkyl ketone of formula II ##STR2## with a cyclic amine of formula III ##STR3## in water at a temperature of at least 130° C., in which ... | 11/02/1999 |
| 5932582 | Fibrinogen receptor antagonist prodrugs Fibrinogen receptor antagonist alcohol prodrugs having the structure, for example, of X--W--Y--Z--A--B more particularly, ##STR1##... | 08/03/1999 |
| 5922874 | Process for preparing N-aryl-N'-alkyl-piperazines N-aryl-N'-alkyl-piperazines are obtained in a particularly simple manner, in good yields and in short reaction times when an aniline is reacted under pressure with an N-alkyl-bishydroxyethyl-amine in the presence of a strong acid.... | 07/13/1999 |
| 5919930 | Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates. In a process for preparing polycyclic aromatic compounds by cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluo... | 07/06/1999 |
| 5917037 | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines The present invention relates to a process for the preparation of N-carboxyalkyl-3-fluoro-4-dialkylaminoanilines, which comprises reacting, in a first step, an orthonitrochlorobenzene of the formula (1) ##STR1## in which X is Cl or F, with a secondar... | 06/29/1999 |
| 5849912 | Biphenyl derivatives A biphenyl derivative represented by the following formula (I) or a pharmacologically acceptable salt thereof: ##STR1## wherein R1, R2, R3, R4, and R5 are defined in the specification, is clinica... | 12/15/1998 |
| 5739334 | Alkyl derivatives of trazodone with CNS activity Alkyl derivatives of trazodone endowed with pharmacological activity, pharmaceutical compositions containing them, process for preparing them and intermediate compounds useful in their preparation are disclosed.... | 04/14/1998 |
| 5607936 | Substituted aryl piperazines as neurokinin antagonists Disclosed are substituted aryl piperazines of Formula I ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis. In particular compounds of Formula I are shown to be neurokini... | 03/04/1997 |
