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Combination Beverage Container and Spittoon
A combination beverage container and spittoon includes a bottom portion including outer wall and a first inner wall defining a spittoon space.
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| Number | Title | Issue Date |
| 8088921 | Method for producing 3-amidinophenylalanine derivatives The present invention describes a method for the synthesis of enantiomerically pure 3-amidinophenylalanine derivatives, which are used as pharmaceutically effective urokinase inhibitors, by starting from 3-cyanophenylalanine derivatives. The methods of manufacture c... | 01/03/2012 |
| 7989623 | Process for making n-(diphenylmethyl)piperazines The compound of formula (8), in racemic or single enantiomeric form, is useful in making N-(diphenylmethyl)-piperazines such as cetirizine and levocetrizine. wherein Z is preferably phenyl. ... | 08/02/2011 |
| 7884206 | Method for producing 3-amidinophenylalanine derivatives The present invention describes a method for the synthesis of enantiomerically pure 3-amidinophenylalanine derivatives, which are used as pharmaceutically effective urokinase inhibitors, by starting from 3-cyanophenylalanine derivatives. The methods of manufacture c... | 02/08/2011 |
| 7851627 | Optically active carbamates, process for preparation thereof and use thereof as pharmaceutical intermediates The present invention is related to 1-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation o... | 12/14/2010 |
| 7166600 | Thiocarbamate inhibitors of alpha-4 integrins The invention provides novel thiocarbamate alpha-4 inhibitors of the general formula (I) that are resistant to metabolism having improved half-life and/or clearance properties compared to corresponding carbamate compounds wherein substituents L, X, Y, Z, R1 | 01/23/2007 |
| 7098338 | 2,3,4,4a-tetrahydro-1H-pyrazino(1,2-a) quinoxalin-5(6H)one derivatives This invention provides compounds of formula I, wherein R is hydrogen or alkyl of 1–6 carbon atoms; R′ is hydrogen, alkyl of 1–6 carbon atoms, acyl of 2â€... | 08/29/2006 |
| 7094779 | Piperazine oxime dervatives having NK-1 receptor antagonistic activity The present invention relates to a group of novel piperazine oxime derivatives having interesting NK-1 antagonistic activity. The invention relates to compounds of the general formula (1) wherein: X represents phenyl or pyridyl substituted with 1 or 2 substituents f... | 08/22/2006 |
| 7022707 | Piperazine derivatives The present invention is a chemical compound of formula (I) or a pharmaceutically acceptable salts, solvates and esters thereof, wherein R1 to R4, A1, A2 m and n are as descri... | 04/04/2006 |
| 7015323 | Thiocarbamate inhibitors of alpha-4 integrins The invention provides novel thiocarbamate alpha-4 inhibitors of the general formula (I) that are resistant to metabolism having improved half-life and/or clearance properties compared to corresponding carbamate compounds wherein substituents L, X, Y, Z, R1 | 03/21/2006 |
| 6906074 | 2-phenylpiperazine derivatives A 2-phenylpiperazine derivative represented by the formula (I) or a pharmaceutically acceptable salt, hydrate, or complex thereof: wherein each of X1 and X3 is oxygen or two hydrogen atoms, X... | 06/14/2005 |
| 6878707 | Carboxamides useful as inhibitors of microsomal triglyceride transfer protein and of apolipoprotein b secretion Compounds of formula (I) wherein R2—C, R3—C, R4—C or R5—C may be replaced by N; and wherein n is 1, 2 or 3; R1 is aryl, heteroaryl or (aryl or heteroaryl)-lo... | 04/12/2005 |
| 6809202 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof The synthesis of individual di- and tri-substituted-1,4-diazacyclic compounds having 6- to 8-atoms in the cyclic ring, their corresponding 1,6-diketo-2,5-diazacyclic compounds and similar 1,4-diazacyclic ring compounds having one ring carbonyl gorup and 6-8 atoms in... | 10/26/2004 |
| 6803465 | Optically active 4-(tert-butoxycarbonyl)piperazine compound, and method for producing the same A method for producing 1-[(substituted phenyl)phenylmethyl]piperazines useful as intermediates for pharmaceuticals and the like, more particularly, for example, to an intermediate for the production of antiallergic pharmaceuticals. A 4-(tert-butoxycarbonyl)piperazin... | 10/12/2004 |
| 6787543 | Benzhydryl derivatives A compound of the formula (I): in which Z, R1, R2, R8, R10, R11, R12, R13 and R14 are each as defined in the description, or a salt thereof. The object compound of the present in... | 09/07/2004 |
| 6762300 | Method for producing 5-(1-piperazinyl)-benzofuran-2-carboxamide by transition metal-catalyzed amination Process for the preparation of 5-(1-piperazinyl)benzofuran-2-carboxamide in which, as intermediate step, 5-bromosalicylaldehyde or one of its derivatives is reacted in a transition metal-catalysed amination with R2-piperazine, in which R2 is as... | 07/13/2004 |
| 6723730 | Capsaicin receptor ligands Disclosed are diaryl piperazines and related compounds of the following Formula: wherein the variables are as defined in the specification. These compounds are selective modulators of capsaicin receptors, including human... | 04/20/2004 |
| 6696447 | Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain The present application describes compounds of general formula I ##STR1## where R1 is selected from any one of pyridinyl, thienyl, furanyl, imidazolyl, and triazolyl; and where each R1 heteroaromatic ring may optionally and independen... | 02/24/2004 |
| 6525036 | Compounds and compositions as protease inhibitors The present invention relates to novel cysteine protease inhibitors of Formula I: ##STR1## the pharmaceutically acceptable salts and N-oxide derivatives thereof, their use as therapeutic agents and methods of making them.... | 02/25/2003 |
| 6441172 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof The synthesis of individual di- and tri-substituted-1,4-diazacyclic compounds having 6- to 8-atoms in the cyclic ring, their corresponding 1,6-diketo-2,5-diazacyclic compounds and similar 1,4-diazacyclic ring compounds having one ring carbonyl group and 6... | 08/27/2002 |
| 6395737 | Malonic acid derivatives, processes for their preparation, for their use and pharmaceutical compositions containing them New compounds for the inhibition of blood clotting proteins, and more particularly, to malonic acid derivatives of the formula I, ##STR1## wherein R(1), R(2), R(3), R(4), R(5), and R(6) have the meanings indicated in the claims. The compounds of formula I... | 05/28/2002 |
| 6369225 | Compounds having activity as inhibitors of cytochrome P450RAI Compounds having Formula 8 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##... | 04/09/2002 |
| 6369226 | Substituted benzamide inhibitors of rhinovirus 3C protease Nonpeptide benzamide-containing inhibitors of human rhinovirus (HRV) 3C protease are described.... | 04/09/2002 |
| 6362373 | Chiral amino alcohols and process for preparation of same The disclosed invention comprises a compound having the formula: ##STR1## in which R1 and R2 independently represent a hydrogen or an alkyl group of 4 carbon atoms or greater. Further disclosed is a process for the preparation of the... | 03/26/2002 |
| 6358956 | Inhibitors of prenyl-protein transferase The present invention comprises piperazine-containing compounds which inhibit prenyl-protein transferases, including-farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of canc... | 03/19/2002 |
| 6303611 | Kappa agonist compounds and pharmaceutical formulations thereof Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formula having the structure: ##STR1## wherein R1, R2, and X Y, Z, Ar and n are as describe... | 10/16/2001 |
| 6248886 | Heterocyclic oxonol infrared rediation sensitive compounds Infrared radiation-sensitive heterocyclic oxonol compounds have been found that are represented by Structure DYE as follows: ##STR1## wherein R is a secondary or tertiary amine, R1 and R2 are independently heterocyclic or carbocyclic... | 06/19/2001 |
| 6197770 | Alkenyl- and alkynl-containing metalloprotease inhibitors Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the compounds have a structure according to the following Formula (I): #... | 03/06/2001 |
| 6177464 | Ring opening metathesis of alkenes Methods for performing ring-opening cross-metathesis reactions on solid support are disclosed. Substituted cyclic compounds, libraries of the compounds, and methods of using the compounds to treat bacterial infections are also disclosed.... | 01/23/2001 |
| 6174885 | [6-(substituted-methyl)-3-cyclohexenyl] formamide derivative, hair growth promoter and external composition for skin A [6-(substituted-methyl)-3-cyclohexenyl]formamide derivative or a salt thereof expressed by the following Formula (I): ##STR1## wherein one of A and B is a hydrocarbon group of C10-30 expressed by R1 and the other is--(CH2 | 01/16/2001 |
| 6140501 | Substituted [2-(1-piperazinyl)ethoxy]methyl compounds Novel substituted [2-(1-piperazinyl)ethoxy]methyl compounds. The present invention related to novel substituted [2-(1-piperazinyl)-ethoxy]methyl compounds of formula ##STR1## in which R1 represents a --CONH2, --CN, --COOH, --COOM or ... | 10/31/2000 |
| 6114325 | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same A 1,2-di-substituted benzene-carboxamide derivative or a salt thereof expressed by the following Formula (I); ##STR1## wherein each of A and B is R1 or --(CH2)n-NR2 R3, wherein when A is R1, B is... | 09/05/2000 |
| 6093823 | Process for the continuous production of basic cyclic optically active - amino acids The invention pertains to a process for the continuous production of basic cyclic optically active -amino acids of general formula (I) by continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the residual amino acid or... | 07/25/2000 |
| 6057323 | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compound of formula I, having the structure: ##STR1## wherein R1, R2 ... | 05/02/2000 |
| 6028195 | Piperazine derivatives and process for the preparation thereof The present invention relates to novel compound having strong antimumor activities of the general formula(I) ##STR1## wherein R1 and R2 are independently hydrogen, substituted or unsubstituted C1 -C8 alkyl,... | 02/22/2000 |
| 5952503 | Method for producing optically-active 2-piperazinecarboxylic acid derivatives Optically-active 2-piperazinecarboxylic acid derivatives are produced through diastereomer salt resolution using optically-active acidic amino acid derivative as the resolving reagent. In this method, the recovery of the resolving reagent used is high, an... | 09/14/1999 |
| 5945534 | Process for the preparation of optically active piperazine-2-carboxylic acid derivatives Optically active piperazine-2-carboxylic acid derivatives of the general formula: ##STR1## in which X is alkoxy or a (substituted) amino group, are prepared by asymmetric hydrogenation of the corresponding pyrazinecarboxylic acid derivatives, ca... | 08/31/1999 |
| 5935997 | O-thiocarbamoyl-aminoalkanol compounds, their pharmaceutically useful salts and process for preparing the same The present invention relates to O-thiocarbamoyl-aminoalkanol compound represented by the following structural formula (VI), (VIII) and (IX) which are a racemic or enantiomerically enriched and pharmaceulically acceptable salts thereof to treat diseases o... | 08/10/1999 |
| 5922872 | Meta-benzylic and alpha-amido compositions and methods for preparing same Compositions comprising meta-benzylic compounds are prepared. The compositions are useful as antibacterial and as other pharmaceutical agents and as intermediates for preparation of other pharmaceutical agents. In addition, compositions of the present inv... | 07/13/1999 |
| 5922707 | Oxazolidinone antibacterial agent with tricyclic substituents This invention provides novel oxazolidinone derivatives represented by chemical Formula (I), or pharmaceutically acceptable salts thereof: ##STR1## wherein X is NR1, CR2 R3, O, S, SO, or SO2 ; and Z is NR | 07/13/1999 |
| 5919777 | Compounds with growth hormone releasing properties The present invention relates to novel compounds of the general formula I ##STR1## which can be used for treating medical disorders resulting from a deficiency in growth hormone.... | 07/06/1999 |
