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Patent No. 5678617

Method and apparatus for making a drink hop along a bar or counter

A method for generating a drink which appears to hop from a remote spot on the bar or counter and take one or more leaps, before landing in a patron's glass.

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Class 544/375 - Polycyclo ring system having the additional hetero ring as one of the cyclos


Subclass of Class 544 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the additional hetero ring is one of the
No. of patents: 169
Last issue date: 04/12/2011


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NumberTitleIssue Date
7923558Method for obtaining pure tetrahydrocannabinol
The invention relates to a method for obtaining pure tetrahydrocannabinol from reaction mixtures containing tetrahydrocannabinol compounds or from raw products containing tetrahydrocannabinol compounds. According to said method, the tetrahydrocannabinol compounds in...
04/12/2011
7390898Cytotoxic agents containing novel potent taxanes and their therapeutic use
Included within the scope of the present invention are potent taxanes containing a linking group. Also included is a cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for inducing cell death in selected cell pop...
06/24/2008
7271168Piperazine derivatives having SST1 antagonistic activity
The invention provides compounds of formula (1) wherein X, R1 and R2 are as defined in the specification, their, preparation and to their use in treating, e.g., depression, anxiety an...
09/18/2007
7223789Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
The present invention relates to novel heterocyclic compounds, their analogs, their tautomers, their regioisomers, their stereoisomers, their enantiomers, their diastereomers, their polymorphs, their pharmaceutically acceptable salts, their appropriate N-oxides, the...
05/29/2007
7186752Derivatives of N-(iminomethyl)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them
N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species. ...
03/06/2007
7119214Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A):
10/10/2006
7094368Pyrano-quinolines, pyrano-quinolinones, combinations thereof, photochromic compositions and articles
Described are compositions of at least one material represented by a pyrano[3,2-c]quinoline structure, a pyrano[3,2-c]quinolinone structure or mixtures thereof. The pyrano[3,2-c]quinoline structure is characterized by having a nitrogen atom at the 6-position ring at...
08/22/2006
7074782Carbamate caspase inhibitors and uses thereof
This invention provides caspase inhibitors of formula I: wherein Z is oxygen or sulfur; R1is hydrogen, —CHN2, R, CH2OR, CH2SR, or —CH2Y; Y is an electron...
07/11/2006
6821967Substituted piperazine derivatives, the preparation thereof and their use as medicaments
The present invention relates to substituted piperazine derivatives of general formula wherein Ra, Rb, Rc, Rf, Rg, X, m and n are defined as in claim 1, ...
11/23/2004
6777414Nitrogen-containing heterocyclic compounds and benamide compounds and drugs containing the same
Disclosed are compounds represented by formula (I) which have triglyceride biosynthesis inhibitory activity in the liver and inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein from the liver and particularly have excellent inhibitor...
08/17/2004
6716987Derivatives of benzofuran or benzodioxazole compounds
An oxygen-containing heterocyclic compound represented by following Formula (I): wherein R1 and R2 independently represent hydrogen, lower alkyl, cyano, —(CH2)n—E1
04/06/2004
6613762Gambogic acid, analogs and derivatives as activators of caspases and inducers of apoptosis
The present invention is directed to gambogic acid, analogs and derivatives thereof, represented by the general Formulae I-III: ##STR1## wherein R1 -R5 are defined in the specification....
09/02/2003
6514996Derivatives of benzofuran or benzodioxole
An oxygen-containing heterocyclic compound represented by following Formula (I): ##STR1## wherein R1 and R2 independently represent hydrogen, lower alkyl, cyano, --(CH2)n --E1 --CO--G1 (whe...
02/04/2003
6511976Halogen substituted tetracyclic tetrahydrofuran derivatives
This invention concerns the compounds of formula (I), ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is zero, 1, 2, 3, 4, 5 or 6; X is CH2 or O; R1
01/28/2003
6492368Benzamidine derivatives as factor XA inhibitors
Novel compounds of the formula I ##STR1## in which X, Y, R1, R2 and R3 are as defined in Patent Claim 1 are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders....
12/10/2002
6429312N-aminoalkyldibenzothiopencarboxamide receptor subtype specific ligands
Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R1, R2, R3, R4 are the same or different and represent hydrogen, C1 -C6 ...
08/06/2002
63918824,5,6 and 7-indole and indoline derivatitives, their preparation and use
A substituted 4-, 5-, 6-, and 7-indole derivative of Formula (I) ##STR1## wherein A is a group having formula (IIA), (IIB), (IIC) ##STR2## wherein X, U, Y, R3 to R12, Z, W, n and m are as defined above. The compounds are potent serot...
05/21/2002
6372738Cytotoxic agents comprising taxanes and their therapeutic use
A cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more taxanes covalently bonded to a cell binding agent through a ...
04/16/2002
6353102Photochromic naphthopyrans
Described are novel photochromic naphtho[1,2-b]pyran compounds having certain substituents at the 2 position of the pyran ring, certain substituents at the 5 and 6 positions and optionally at the 7, 8, 9 and 10-positions of the naphtho portion of the comp...
03/05/2002
6333324Piperazine compounds as inhibitors of MMP or TNF
A compound of formula (I) wherein A is a sulfonyl or a carbonyl; R1 is an optionally substituted aryl, an optionally substituted heterocyclic group, an optionally substituted lower alkyl or an optionally substituted lower alkenyl; R2...
12/25/2001
6323206Chemokine receptor antagonists and methods of use therefor
Disclosed is a method of treating a subject with a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to the subject a therapeutically effective amount of a compound represented by the following st...
11/27/2001
6281361Dibenzonaphthyrones
Dibenzonaphthyrone of formula (I) ##STR1## wherein A1 and A2 independently of each other are unsubstituted or mono- to tetra-substituted o-C6 -C18 arylene, with the proviso that formula (I) does not represent a ...
08/28/2001
6214827Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
Novel compounds of Formula ##STR1## are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the above formula to a biological system. In ...
04/10/2001
6156790C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities
The present invention provides a two-step procedure for the replacement of the pyranose anomeric 10-OH group in dihydroartemisinin by a variety of carbon nucleophiles, resulting in the novel C-10 carbon-substituted trioxanes of structure: ##STR1## ...
12/05/2000
6130101Sulfonated xanthene derivatives
The present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulfonic acid. The dyes of the invention, including chemically reactive dyes and dye-con...
10/10/2000
6096740Dexanabinol derivatives and their use as neuroprotective pharmaceutical compositions
The present invention relates to pharmaceutical compositions for preventing or alleviating neurotoxicity. Said pharmaceutical compositions comprise as their active ingredient the stereospecific (+) enantiomers, having (3S,4S) configuration, of Ɗ6
08/01/2000
6060468N-substituted azaheterocyclic compounds
The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula ##STR1## wherein X, Y, Z, R1, R1a, R2, R2a, p, r and s are as defined in the detailed part of the presen...
05/09/2000
6057441Substituted tetracyclic tetrahydrofuran derivatives
This invention concerns the compounds of formula (I), ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, wherein n is zero to 6; p and q are zero to 4; r is zero to 5; R1 and R
05/02/2000
6054458Heterocyclic compounds
The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula ##STR1## wherein X, Y, Z, R1, R2 and m are as defined in the detailed part of the present description, or salts thereof, to me...
04/25/2000
6025385Taxane derivatives and drugs containing the same
This invention relates to a taxane derivative represented by the following formula (1): wherein at least one of X and Y represents a group --CO--A--B in which A represents a single bond, an alkylenecarbonyl group or the like and B represents a substituted...
02/15/2000
6022497Photochromic six-membered heterocyclic-fused naphthopyrans
Described are novel photochromic six-membered heterocyclic-fused naphthopyran compounds, examples of which are naphthopyran compounds having a substituted or unsubstituted six-membered heterocyclic group fused to one side of the naphtho portion of the nap...
02/08/2000
6017915Heterocyclic compounds
The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing...
01/25/2000
59984644-Oxa and 4-thia steroids
The compounds of the present invention are those of structural formula (I) ##STR1## wherein X is oxygen or sulfur. Pharmaceutical compositions and methods of use of the compounds in the treatment of hyperandrogenic conditions are disclosed. In additi...
12/07/1999
5932725Chromene compound
The present invention relates to a novel chromene compound having favorable photochromic properties, developing a color of a high density, exhibiting a small degree of initial color and permitting the color to quickly fade. The novel chromene compound has...
08/03/1999
59168891,4-disubstituted piperazines
The present invention relates to 1,4-disubstituted piperazines of the general formula ##STR1## wherein X, Y, Z, R1, R2 and r are as defined in the detailed part of the present description or salts thereof, to methods for their ...
06/29/1999
5891368Fluoranthenopyrans
Described are novel photochromic 8-substituted fluoranthenopyran compounds having certain substituents at the 5 position of the pyran ring. These compounds may be represented by the following graphic formula: ##STR1## Also described are polymeric org...
04/06/1999
5877317Heterocyclic compounds for the treatment of CNS and cardiovascular disorders
Novel aromatic bicyclic amines of formula (I) ##STR1## are useful in treating central nervous system disorders and cardiac arrhythmias and cardiac fibrillation....
03/02/1999
5834459Alkyl-substituted compounds having dopamine receptor affinity
Described herein are D4 receptor-selective compounds of the general formula: ##STR1## wherein: A and B are independently selected, optionally substituted, unsaturated 5- or 6-membered, homo- or heterocyclic rings; X1 is selected from CH
11/10/1998
5801175Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
Novel compounds of Formula ##STR1## are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the above formula to a biological system....
09/01/1998
5783116Derivatives of carbocyclic fused naphthopyrans
Described are novel pentahydrophenanthro›9,10-b!pyrans and tetrahydrocyclopenta›c!-naphtho›1,2-b!pyrans. Also described are polymeric organic host materials that contain or that are coated with such compounds....
07/21/1998
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