Celebrity Inventors
Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8022209 | Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine Hreceptor The present invention relates to substituted nitrogen-containing heteroaryl derivatives, pharmaceutical compositions containing them, and methods of using any of these derivatives and compositions for H4 receptor activity modulation and the treatment of s... | 09/20/2011 |
| 8013156 | Tie-2 modulators and methods of use The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/... | 09/06/2011 |
| 7582760 | Benzimidazolone and dihydroindolone derivatives and uses thereof Compounds of the formula I: or pharmaceutically acceptable salts thereof wherein m, n, X, Ar, R1, R2, R3, R4 and R5 are as defined herein. Also provided are methods for... | 09/01/2009 |
| 7425557 | Inhibitors of glycogen synthase kinase 3 New pyridine-based compounds of Formula I, compositions, and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3-mediated disorders in vivo are provided. The methods, compounds, and compositions of the invention ma... | 09/16/2008 |
| 7423048 | Compounds for treating fundic disaccomodation The present invention concerns compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof, wherein -a1═a2-a... | 09/09/2008 |
| 7417045 | Heterocyclic substituted pyridine or phenyl compounds with CXCR3 antagonist activity The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prod rug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having the general ... | 08/26/2008 |
| 7402675 | Process for the synthesis of amine ethers from secondary amino oxides An amine ether of formula A wherein a is 1 or 2; and when a is 1, E is E′; when a is 2, E is L; E′ is C1-C36 alkyl; C3-C18 alkenyl; C2 | 07/22/2008 |
| 7402581 | Azetidine compounds The present invention relates to a compound of the general formula (I) wherein Het is an optionally substituted 4-, 5-, 6- or 7-membered heterocyclic ring having at least one nitrogen atom; R1 is hydrogen, hydroxy, C1-C4 alkyl, C3-C | 07/22/2008 |
| 7384962 | Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them The present invention relates to novel heterocyclic compounds, their analogs, their tautomers, their regioisomers, their stereoisomers, their enantiomers, their diastereomers, their polymorphs, their pharmaceutically acceptable salts, their appropriate N-oxides, the... | 06/10/2008 |
| 7384943 | Substituted chroman derivatives The present invention relates to new piperidyl- or piperazinyl-substituted dihydro-2H-1-benzopyran derivatives having the formula (I) wherein X is N; Y is NR2CH2, CH2 | 06/10/2008 |
| 7381727 | Pyrrole derivatives, their preparation and their therapeutic use The invention concerns compounds of formula (I): Wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The in... | 06/03/2008 |
| 7371755 | Antiviral agents This invention relates to a compound capable of binding to a picornavirus capsid comprising two or more capsid binding moieties. ... | 05/13/2008 |
| 7365075 | Aryl sulfonamide compounds and uses related thereto The present invention provides Aryl Sulfonamide Compounds having the formula: and prodrugs or pharmaceutically acceptable salts or prodrugs thereof. The Aryl Sulfonamide Compounds are useful for treating diabetes, obesity, ... | 04/29/2008 |
| 7361654 | Substituted heteroaryl amide modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof The present invention relates to new class of non-steroidal compounds which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity including obesity, diabetes, inflammatory- and immune-associated disea... | 04/22/2008 |
| 7361658 | 2-acylaminothiazole derivative or salt thereof 2-Acylaminothiazole derivatives or salts thereof which have a platelet increasing activity based on an excellent human c-mpl-Ba/F3 cell growth function and a function of accelerating formation of megakaryocytic colonies and which are useful for treating thrombocytop... | 04/22/2008 |
| 7309800 | Biphenylcarboxylic amide derivatives as p38 kinase inhibitors Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors. ... | 12/18/2007 |
| 7300936 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of β-amyloid peptid... | 11/27/2007 |
| 7285553 | Serotonergic 5HTreceptor compounds for treating ocular and CNS disorders Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for... | 10/23/2007 |
| 7279475 | Fluorinated di-aryl urea compounds Disclosed are compounds of formula(I): wherein R1, R2, W and X of formula(I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus... | 10/09/2007 |
| 7271181 | Inhibitors of p38 The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceut... | 09/18/2007 |
| 7256188 | 3-aminoalkyl-2-aryl-indole derivatives and their use as GnRH antagonists The present invention relates to compounds of formula I which are antagonists of gonadotropin releasing hormone (GnRH) activity. The invention also relates to pharmaceutical formulations, the use of a compound of the present invention in the manufacture of a medicam... | 08/14/2007 |
| 7253165 | Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as Dantagonists The compounds are of the class of benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives, useful as D4 antagonists. Said compounds are useful for the treatment of medical conditions mediated by inhibition of D4 receptor. These c... | 08/07/2007 |
| 7220753 | 2,7-substituted octahydro-1H-pyrido[1,2-a]pyrazine derivatives as ligands for serotonin receptors Substituted pyrido[1,2-a]pyrazines of general formula I; wherein Ar and Ar1 represent various carbocyclic and heterocyclic aromatic rings; A represents O, S, SO, SO2, CHOH, C═O, or —(CR3R4); and n is 0–2, as well as ... | 05/22/2007 |
| 7217714 | CCR5 modulators Compounds of Formula 1 [Region α]−[Region β]−[Region γ]−[Region δ] (I) which are useful as modulators of chemokine activity. The invention also provides pharmaceutical formulations and m... | 05/15/2007 |
| 7176236 | Water-soluble etoposide analogs and methods of use thereof Etoposide analogs with improved water-solubility such as 4′-O-Demethyl-4′-(N′,N′-dimethyl-glycyl)-4β-(4″-nitroanilino)-4-desoxy-podophyllotoxin (8) and 4′-O-Demethyl-4′-(N′,N′-dimethyl-glycyl)-4β-(4″-fluoroanilino)-4-desoxy-podophyllotoxin (9) ... | 02/13/2007 |
| 7153857 | Arylpiperazines and arylpiperidines and their use as metalloproteinase inhibiting agents Compounds of the formula I useful as metalloproteinase inhibitors, especially as inhibitors of MMP 13. ... | 12/26/2006 |
| 7151118 | Biphenylcarboxylic amide derivatives as p38-kinase inhibitors Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors. ... | 12/19/2006 |
| 7150967 | Fluorescent tags for amino acid and nucleic acid analysis Methods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluoresce... | 12/19/2006 |
| 7148240 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives of general formula: These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes of the cardiovascular... | 12/12/2006 |
| 7115607 | Substituted piperazinyl amides and methods of use Selected substituted piperazine compounds of Formula I are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceuti... | 10/03/2006 |
| 7074794 | Proline derivatives and the use thereof as drugs The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the γ-position... | 07/11/2006 |
| 7064201 | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof Compounds represented by the following structure (I) are disclosed: as are methods for making such compounds, wherein said methods comprise reacting a diacyldiketopiperazine with a first aldehyde to produce an in... | 06/20/2006 |
| 7056921 | Substituted chroman derivatives The present invention relates to new new piperidyl- or piperazinyl-substituted dihydro-2H-1-benzopyran derivatives compound having the formula (I) wherein X is N or CH; Y is NR2 | 06/06/2006 |
| 7049323 | Amidoheterocycles as modulators of the melanocortin-4 receptor Novel azetidinyl and pyrrolidinyl compounds are ligands of melanocortin-4 receptors and are useful for treating conditions responsive to the modulation of melanocortin-4 receptors such as obesity, diabetes, and sexual dysfunction. | 05/23/2006 |
| 7041825 | Additive compound for curing halogenated polymers The present invention relates to 1,3,4-thiadiazole reaction products useful as accelerators and/or curing agents for halogenated polymers in rubber vulcanization processes, and to halogenated polymer compositions containing the thiadiazole derivatives, as well as a ... | 05/09/2006 |
| 7030122 | 1,4-disubstituted piperazine ligands for neurotransmitter receptors One aspect of the present invention relates to novel heterocyclic compounds. A second aspect of the present invention relates to the use of the novel heterocyclic compounds as ligands for various cellular receptors, including serotonin receptors and dopamine recepto... | 04/18/2006 |
| 7030241 | Mesylates of piperazine derivatives and process for their preparation The invention relates to the mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine rin... | 04/18/2006 |
| 6998272 | Macrocyclic compounds and their use The subject invention pertains to macrocyclic compounds, and their use, the compounds having the formula (I) wherein X is a ring bearing an optionally-protected functional group or solid phase group R1, Y is ... | 02/14/2006 |
| 6982332 | Hybrid 2-aminotetralin and aryl-substituted piperazine compounds and their use in altering CNS activity Compounds exhibiting CNS activity in mammalian species, having the structure wherein A is an optionally heterocyclic 5 or 6 membered aromatic ring system; R2 | 01/03/2006 |
| 6969730 | Amines as histamine-3 receptor ligands and their therapeutic applications Compounds of formula (I) or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the treatment of disorders amelior... | 11/29/2005 |
