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| Number | Title | Issue Date |
| 5051504 | Doubled triphenylmethane dyes having bis acylpiperazine linkage Triphenylmethane dyes of the formula ##STR1## where each R1 is independently of the others hydrogen or substituted or unsubstituted C1 -C6 -alkyl, or two R1 radicals together with the nitrogen atom joining ... | 09/24/1991 |
| 5049670 | Perfluoroaminoethers Perfluoroaminoethers are provided. The perfluoroaminoiethers have two or more tertiary amino nitrogen atoms each of which is connected to the other(s) adjacent thereto by (1) a catenary, ether oxygen-containing, perfluoroalkylene linking group the catenar... | 09/17/1991 |
| 5047406 | Substituted cyclohexanols as central nervous system agents Substituted cyclohexanols and cyclohexylamines and derivatives thereof are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminer... | 09/10/1991 |
| 5043443 | Aminomethyloxooxazolidinyl arylbenzene derivatives Novel aminomethyloxooxazolidinyl arylbenzene derivatives, wherein the aryl includes the phenyl, substituted phenyl, pyridyl, and substituted pyridyl groups, such as (l)-N-{3-[4- (4'-pyridyl)phenyl]-2-oxooxazolidin-5-ylmethyl}acetamide, possess useful ... | 08/27/1991 |
| 5036070 | Polycyclic phenalkyl amines as psychotropic agents There are disclosed compounds of the formula ##STR1## wherein R1 and R2 are each, independently, hydrogen, alkyl, or phenyl, or R1 and R2 taken together represent --(CH2)4 -- or #... | 07/30/1991 |
| 5030740 | Process for preparing linearly-extended polyalkylenepolyamines A process for preparing linearly-extended polyalkylenepolyamines, such as linear and branched polyethylenepolyamines, comprising contacting a difunctional aliphatic alcohol, such as monoethanolamine, with a reactant amine, such as ethylenediamine, in the ... | 07/09/1991 |
| 5028610 | N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use Compounds of formula (I): A--M--B-- (I) (in which: M represents a saturated heterocyclic group having from 5 to 7 ring atoms of which 2 are nitrogen atoms, said group being unsubstituted or being substituted at ... | 07/02/1991 |
| 5023258 | Triazole antifungal agents The invention provides triazole antifungal compounds of the formula: ##STR1## wherein R is either (a) a phenyl group optionally substituted with 1 to 3 substituents, each selected independently from halo and CF3 ; or (b) a 5-chloropyridin-2-yl ... | 06/11/1991 |
| 5015736 | Piperazine intermediates A new compound called N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine of Formula I ##STR1## A process for the preparation thereof based on the reaction of 4-ethyl-2,3-dioxo-piperazine or a trimethylsilyl derivative thereof with carbonyl chlorid... | 05/14/1991 |
| 5013836 | Process for methylating a hindered nitrogen atom in a polysubstituted diazacycloalkan-2-one The difficulty of methylating a hindered piperidinyl, piperazinyl, or diazepinyl group with an Eschweiler-Clarke ("E-C") procedure without using a large molar excess (more than double) of formaldehyde is surprisingly found to be non-existent in the case o... | 05/07/1991 |
| 5013732 | 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles 3-Arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, useful as analgesic, anti-rheumatic and anti-inflammatory agents, are prepared by reacting a 3-arylcarbonyl- or 3-cycloalkylcarbonylindole with an aminoalkyl halide in the presence of an ac... | 05/07/1991 |
| 5013840 | Polyamic acid or polyimide A polyamic acid or polyimide having 2,5-distyrylpyrazine units in the main chain thereof.... | 05/07/1991 |
| 5011925 | Morpholinoamido EDTA derivatives Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with aminoalkylamide derivatives of diethylenetriaminepentaacetic acid ("DTPA") or ethylenediaminetetraacetic acid ("EDTA") or other polyaminocarboxylic or cyclic polyaminocar... | 04/30/1991 |
| 5011842 | 2-(heterocyclylalkyl)imidazopyridines for treating allergic diseases 2-(Heterocyclylalkyl)imidazopyridines having antihistaminic properties, compositions containing these compounds as active ingredient and novel 2-(Heterocyclylalkyl)imidazopyridines.... | 04/30/1991 |
| 5001237 | 2-substituted alkoxy-3-substituted-pyrazines A compound of the formula ##STR1## wherein Q is --CO-- or --CH2 --, R is hydroxyl, lower alkoxy, halogen, --NH-lower alkylene-OH, --NH-lower alkylene-arylthio, --NH-lower alkylene-halogen, ##STR2## is dilower alkylamino, cycloalk... | 03/19/1991 |
| 4996318 | Amino-9,10-secosteroids useful for treating head injury, spinal cord trauma or stroke The amino-9,10-secosteroids ##STR1## of the present invention contain an amino group attached to the terminal carbon atom of the C17 -side chain and are useful as pharmaceutical agents for treating a number of conditions including spinal t... | 02/26/1991 |
| 4996212 | Antiinflammatory and anti-hyperproliferative compounds Tricyclic pyrrolo naphthyridinone compounds are disclosed, which are useful as antiinflammatory and anti-hyperprolferative agents.... | 02/26/1991 |
| 4990590 | Anionic slurry seal emulsifiers An anionic emulsifier obtained from the reaction products of an alkyl phenol, polyamine, and formaldehyde or of an alkyl phenol, fatty acid/polyamine condensate, and formaldehyde followed by the reaction of such products with acrylic acid, and the uses of... | 02/05/1991 |
| 4990591 | Anionic slurry seal emulsifiers An anionic emulsifier obtained from the reaction products of an alkyl phenol, polyamine, and formaldehyde or of an alkyl phenol, fatty acid/polyamine condensate, and formaldehyde followed by the reaction of such products with acrylic acid, and the uses of... | 02/05/1991 |
| 4990592 | Anionic slurry seal emulsifiers An anionic emulsifier obtained from the reaction products of an alkyl phenol, polyamine, and formaldehyde or of an alkyl phenol, fatty acid/polyamine condensate, and formaldehyde followed by the reaction of such products with acrylic acid, and the uses of... | 02/05/1991 |
| 4990672 | Propylene-linked polyethylene polyamines and a process for making same This invention relates to propylene-linked polyethylene polyamines and a process for preparing such propylene-linked polyethylene polyamines. These propylene-linked polyethylene polyamines are characterized as having high molecular weight and the amine va... | 02/05/1991 |
| 4988814 | Tertiary alkyl functionalized piperazine derivatives Compounds of the formula: ##STR1## in which R1 is alkyl; R2 and R3 are alkyl or taken together they are polymethylene, R2 and R3 complete a 5-norbornen-2-yl moiety; X is --CO2 --, --OC... | 01/29/1991 |
| 4987146 | N-hetaryl imidazole derivatives N-hetaryl imidazole derivatives of general Formula I ##STR1## are disclosed in which Het represents an optionally substituted monocyclic or bicyclic heteroaromate, R3 represents hydrogen, a straight or branched C1-6 -alkyl group, or ... | 01/22/1991 |
| 4987132 | Saturated heterocyclic carboxamide derivatives A saturated heterocyclic carboxamide derivative of the following general formula (I) and salts thereof which have platelet activating factor (PAF) antagonizing activity. ##STR1##... | 01/22/1991 |
| 4985583 | Cyclohexane derivatives New cyclohexane derivatives of the formula I R1 --A1 --Z1 --A2 --R2 I wherein R1 and R2 are each H, an unsubstituted or substituted alkyl group with 1-15 C atoms, it also being ... | 01/15/1991 |
| 4983736 | Amines catalysis using metallic polyphosphate condensation catalysts having a condensed structure This invention relates to a process for making amines by condensing an amino compound in the presence of a metallic polyphosphate condensation catalyst having a condensed structure. This invention also relates to an alkyleneamines producers composition ri... | 01/08/1991 |
| 4981978 | Reaction products of imidazole on pyrazole derivatives and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde Thermosettable prepolymers or resins are prepared by reacting (1) a pyrazine compound containing at least two substituent groups which have a hydrogen atom attached to a carbon atom which is attached to the ring such as tetramethylpyrazine, (2) a material... | 01/01/1991 |
| 4978662 | 2-substituted trimethylpyrazine derivatives as inhibitors of platelet function Novel 2-substituted trimethylpyrazine derivatives of the formula: ##STR1## wherein R is alkylamino, 4-methyl-1-piperazinyl, piperidino, morpholino or 2-trimethylpyrazinepropenyl. These novel 2-substituted trimethylpyrazine derivatives exhibit, at very ... | 12/18/1990 |
| 4975445 | Substituted cyclohexenes as central nervous system agents Substituted cyclohexenes are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agent... | 12/04/1990 |
| 4970211 | Ionene polymeric compositions, their preparation and use Novel capped polymeric quaternary ammonium compositions formed by reacting ionene type polymers with tertiary amines are useful as microbicides, corrosion inhibitors, debonding agents, flocculants, softeners, plant growth regulators, and demulsifiers.... | 11/13/1990 |
| 4968714 | Fungicidal substituted 3-amino-2-pyrazolin-5-ones, compositions and use Fungicidal substituted 3-amino-2-pyrazolin-5-ones of the formula ##STR1## in which R1 represents unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl or alkinyl, or unsubstituted or substituted cycloalkyl or cycloalkeny... | 11/06/1990 |
| 4968706 | Ethers and thioethers having therapeutical activity, their preparation and pharmaceutical compositions containing them Compounds of formula I ##STR1## wherein Ar is an optionally substituted phenyl ring; B is a single bond, a group --(CH2 OCH2)n being n=1 or 2, a 2,4-disubstituted-1,3-dioxolane ring or a 2,4-disubstituted-1,3-thioxola... | 11/06/1990 |
| 4965358 | N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine A new compound called N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine of Formula I ##STR1## A process for the preparation thereof based on the reaction of 4-ethyl-2,3-dioxo-piperazine or a trimethylsilyl derivative thereof with carbonyl chlorid... | 10/23/1990 |
| 4963551 | Stable lyophilized form of (S)-(+)-bis-4,4'-(1-methyl-1,2-ethanediyl)2,6-piperazinedione and solutions thereof The present invention is directed to a stable, rapidly soluble lyophilized injectable composition containing up to about 6% moisture and capable of being stored at room temperature comprising the hydrochloric or sulfate salt of a compound selected from th... | 10/16/1990 |
| 4963679 | Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes A process for preparing a compound of the formula (I) ##STR1## wherein R1 and R2 are individually selected from the group consisting of hydrogen and methyl or R1 and R2 together represent an ethylene bridge... | 10/16/1990 |
| 4961867 | Process for preventing corrosion of metals by contacting them with compositions prepared from amino substituted pyrazines and carboxylic acids carboxylic acid anhydrides, carboxylic acid, esters or carboxylic acid halides Novel compositions are prepared from (1) amino substituted pyrazine compounds such as pyrazinamine and (2) at least one of (a) a carboxylic acid, (b) carboxylic acid anhydride, (c) carboxylic acid ester or (d) combination thereof, such as tall oil fatty a... | 10/09/1990 |
| 4960776 | 4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides Novel 4-aryl-N-[2-(dialkylamino and heterocyclicamino)alkyl]-1-piperazinecarboxamides of the formula: ##STR1## wherein B is oxygen or sulfur; Ar is selected from ##STR2## or 2, 3 or 4-pyridyl; X is selected from hydrogen, halogen, loweralkyl, ... | 10/02/1990 |
| 4960777 | Heteroaryloxy-ଲ-carboline derivatives, their preparation and their use as medicinal agents Heteroaryloxy-ଲ-carboline derivatives of general Formula I ##STR1## wherein R1 is an optionally substituted heteroaryl residue, R2 is hydrogen, lower alkyl or lower alkoxyalkyl, X is a COOR3 -group wherein R3 m... | 10/02/1990 |
| 4960890 | Methine dyes which have at least one heterocycle containing two nitrogen atoms and preparation thereof Methine dyes (I) which conform in one of their tautomeric forms to the general formula ##STR1## where Y1 is in both or either case an electron-attracting group and the other Y1 is hydrogen, Y2 is in each case, indepen... | 10/02/1990 |
| 4958024 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives A process for preparing a 2-carbamoylocxyalkyl-1,4-dihydropyridine derivative represented by the general formula: ##STR1## which comprises: (a) reacting a 3-amino-3-carbamoyloxyalkylacrylic acid derivative represented by the general formula: ##S... | 09/18/1990 |
