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| Number | Title | Issue Date |
| 8076480 | Process of preparing optically active allyl compound Disclosed is a process of preparing an optically active allyl compound, e.g., as represented by formula (III): comprising asymmetrically coupling an allyl compound with an organic nucleophilic compound in the presence of a ... | 12/13/2011 |
| 8008489 | Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative It is an object to provide a novel bipolar organic compound. In particular, it is an object to provide a bipolar organic compound excellent in thermal stability. Further, it is another object to provide a bipolar organic compound which is electrochemically stable. A... | 08/30/2011 |
| 7947833 | Preparation of quinoxaline compounds Certain methods that are useful in the preparation of amidophenyl-sulfonylamino-quinoxaline compounds are disclosed. The compounds are of the class of quinoxaline sulfonamides and constitute CCK2 receptor modulators, useful in the treatment of gastrointestinal disea... | 05/24/2011 |
| 7855292 | Sulfonamide compounds Certain sulfonamide compounds are dual CCK1/CCK2 inhibitors useful in the treatment of CCK1/CCK2 mediated diseases. ... | 12/21/2010 |
| 7795429 | Organometallic complex, and light-emitting element and light-emitting device using the organometallic complex A material which can emit phosphorescence is disclosed. Further, a light-emitting element having good chromaticity is disclosed. An embodiment of the present invention is an organometallic complex including a structure as represented by the general formula (1): wher... | 09/14/2010 |
| 7696348 | Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative It is an object to provide a novel bipolar organic compound. In particular, it is an object to provide a bipolar organic compound excellent in thermal stability. Further, it is another object to provide a bipolar organic compound which is electrochemically stable. A... | 04/13/2010 |
| 7635775 | Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists Disclosed are sulfonylquinoxalone acetamide derivatives useful as bradykinin antagonists. ... | 12/22/2009 |
| 7626022 | Method for producing β-heteroaryl-α-alanine compounds using 2-amino-2-(heteroarylmethyl) carboxylic acid compounds This invention relates to N and O-protected, optionally substituted β-heteroaryl-α-alanine compounds of the structural Formula I, wherein each of the variables is as set forth in the specification, methods for producing a... | 12/01/2009 |
| 7612204 | Quinoxaline derivative, and light-emitting element and light-emitting device using quinoxaline derivative An object is to provide a novel organic compound capable of visible light emission. In particular, an object is to provide a novel organic compound that exhibits a broad emission spectrum when it is used for a light-emitting element. In addition, an object is to pro... | 11/03/2009 |
| 7563895 | Quinoxaline compounds Certain amidophenyl-sulfonylamino-quinoxaline compounds are CCK2 modulators useful in the treatment of CCK2 mediated diseases. ... | 07/21/2009 |
| 7432264 | Antimicrobial biaryl compounds Provided are antibacterial biaryl compounds having micromolar MIC activity against Gram-negative and Gram-positive pathogens, including a methicillin-resistant S. aureus strain. ... | 10/07/2008 |
| 7432270 | N-aroyl cyclic amines This invention relates to N-aroyl cyclic amine derivatives and their use as orexin antagonists wherein: Y represents a bond, oxygen, or a group (CH2)n, wherein n represents 1, 2 or 3;... | 10/07/2008 |
| 7417062 | Substituted arylamides Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer. ... | 08/26/2008 |
| 7417041 | Imidazopyrimidines as transforming growth factor (TGF) inhibitors Novel fused heteroaromatic compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of tran... | 08/26/2008 |
| 7407958 | 2-pyridyl substituted imidazoles as ALK5 and/or ALK4 inhibitors Compounds of the formula: wherein R1, R2, R3, A1 and A2 are as defined herein, which are used advantageously in inhibiting the TGF-β and/or activin signaling pathway in mammals. ... | 08/05/2008 |
| 7405217 | N-aroyl piperazine derivatives as orexin receptor antagonists This invention relates to N-aroyl cyclic amino derivatives and their use as pharmaceuticals. ... | 07/29/2008 |
| 7405299 | Compounds as pharmaceutical agents The current invention relates to compounds of the formula: (Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said c... | 07/29/2008 |
| 7399432 | Charge transport compositions and electronic devices made with such compositions The present invention relates to charge transport compositions. The invention further relates to electronic devices in which there is at least one active layer comprising such charge transport compositions. ... | 07/15/2008 |
| 7351709 | Estrogen receptor ligands The present invention relates to estrogen receptor ligands, and compounds and methods for treating diseases associated with excessive estrogen receptor activity. Compound of the formula I are disclosed: wherein W is O or (C... | 04/01/2008 |
| 7345090 | Galenical formulation The invention relates to compounds of the formula I where R1, R2, R3, R4 and R5 have the meanings given in claim 1. The compound is suitable in particular for use in sk... | 03/18/2008 |
| 7312000 | Electrolytic solution for secondary battery and secondary battery containing the same A battery, which has excellent safety in an overcharged state and is excellent in low-temperature characteristics and cycle characteristics, is provided. The electrolytic solution of the secondary battery contains a compound which has a diazine N,N′-dioxide... | 12/25/2007 |
| 7312218 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula Ia-If: or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or hetero... | 12/25/2007 |
| 7304051 | Quinoxaline compounds Amidophenyl-sulfonylamino-quinoxaline compounds of formula (I) are CCK2 modulators useful in the treatment of CCK2 mediated diseases. ... | 12/04/2007 |
| 7300941 | Non-imidazole compounds Disclosed are novel compounds of the formula Also disclosed are pharmaceutical compositions comprising the compounds of Formula I. Also disclosed are methods of treating various diseases or conditions, such ... | 11/27/2007 |
| 7297696 | Antagonists of MCP-1 function and methods of use thereof Compounds which are antagonists of MCP-1 function and are useful in the prevention or treatment of chronic or acute inflammatory or autoimmune diseases, especially those associated with aberrant lymphocyte or monocyte accumulation such as arthritis, asthma, atherosc... | 11/20/2007 |
| 7294716 | Process for preparing isomerically pure prodrugs of proton pump inhibitors Synthetic methods for preparing isomerically pure N-arylsulfonyl derivatives of proton pump inhibitors which include a substituted benzimidazole nucleus are shown by the synthetic schemes and experimental description. ... | 11/13/2007 |
| 7273936 | Oxazole and thiazole compounds as transforming growth factor (TGF) inhibitors Novel oxazole and thiazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of tran... | 09/25/2007 |
| 7265116 | Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof Provided herein are compounds of the formula (I): wherein R1-R8 are as described herein, R4 being phthalazinyl, pyrazinyl, pyridazinyl, or quinoxalinyl. Such compounds are particu... | 09/04/2007 |
| 7265378 | Electronic devices made with electron transport and/or anti-quenching layers The present invention is directed to a photoactive device comprising an anode, a cathode, and a photoactive layer, which device further comprises an electron transport and/or anti-quenching layer which minimizes both electron transfer quenching and energy transfer q... | 09/04/2007 |
| 7259163 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors Novel anti-viral agents of Formula wherein: A represents OR1, NR1R2, or R1 wherein R1 and R2 are hydrogen, C1-6alkyl, aryl... | 08/21/2007 |
| 7245073 | Quinoxaline derivatives, and light emitting element using thereof It is an object to provide an organic compound that has a bipolar property and also a light emitting property, and further has heat resistance. A quinoxaline derivative represented by a general formula (1) is provided. In the formula, A represents any one of ... | 07/17/2007 |
| 7232826 | Tyrosine kinase inhibitors The present invention provides compounds of Formula I or II that are useful as anti-cancer agents and other diseases that can be treated by inhibiting tyrosine kinase enzymes ... | 06/19/2007 |
| RE39663 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitrogen heteroc... | 05/29/2007 |
| 7220781 | Meta-benzamidine derivatives as serine protease inhibitors Compounds of formula I in which R1, R2, R3, each X, L, Y, Cy, Lp, D and n have the meanings as set out in the specification, and corresponding compounds in which the unsubstituted... | 05/22/2007 |
| 7214674 | Heterocyclymethylpiperidines and -piperazines possessing affinity at 5ht-1 type receptors Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed: wherein: A is optionally substituted phenyl, naphthyl, indolyl, quinolinyl, quinazolinyl, indazolyl, isoquinolinyl or benzofur... | 05/08/2007 |
| 7205316 | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R... | 04/17/2007 |
| 7189724 | Quinoxaline derivatives having antiviral activity The invention provides substituted quinoxalines having the general formulas where R1, R2, R3, and R4 are, inter alia, alkyl, aryl, or heteroaryl groups; Z is NH or O; a... | 03/13/2007 |
| 7186720 | Tetrahydropyridyl-alkyl-heterocycles, method for preparing the same and pharmaceutical compositions containing the same The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; R2 and R3 independent... | 03/06/2007 |
| 7186730 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man. ... | 03/06/2007 |
| 7183273 | Chemokine receptor binding heterocyclic compounds Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor. ... | 02/27/2007 |
