Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7803941 | Process for preparing ring-fluorinated aromatics The present invention relates to an improved process for preparing ring-fluorinated aromatics of the general formula (I) by a halogen exchange reaction (halex reaction) of a plurality of halogen substituents in one stage in... | 09/28/2010 |
| 7378409 | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis. | 05/27/2008 |
| 7338958 | Sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, ... | 03/04/2008 |
| 7317014 | Bio-active pyrimidine molecules The present invention relates to novel derivatives of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and pharmaceutical... | 01/08/2008 |
| 7312222 | Heterocyclic piperidines as modulators of chemokine receptor activity The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases. ... | 12/25/2007 |
| 7291624 | CDK-inhibitory pyrimidines, their production and use as pharmaceutical agents This invention relates to pyrimidine derivatives of general formula I in which R1, R2, X, A and B have the meanings that are contained in the description, as inhibitors of the cyclin-depende... | 11/06/2007 |
| 7291730 | Pyrimidine compounds and their use Pyrimidine compounds of formula (1): wherein R1 is C3-C7 alkynyl optionally substituted with halogen; R2 and R3 are independently hydrogen or the like; and R... | 11/06/2007 |
| 7271263 | Process for production of substituted aniline compound The present invention provides a process for producing a substituted aniline compound represented by the following general formula (6): (in the formula, R1, R2 and R3 are each ind... | 09/18/2007 |
| 7265115 | Diazabicyclic CNS active agents Compounds of formula I: or pharmaceutically acceptable salts thereof, are useful for controlling synaptic transmission in mammals. ... | 09/04/2007 |
| 7202236 | Modified release pharmaceutical formulation A modified release pharmaceutical composition comprising, as active ingredient, a compound of formula (I), wherein R1 represents C?1-2#191 alkyl substituted by one or more fluoro substituents; R2 represents hydrogen, hydroxy, methoxy or ethoxy;... | 04/10/2007 |
| 7196226 | Fluoraminoolefins and fluorination reagents which can be prepared therefrom The present invention relates to fluorination reagents comprising 1-fluoro-1-aminoolefins and also processes for preparing fluorination reagents comprising 1-fluoro-1-aminoolefins. ... | 03/27/2007 |
| 7153815 | Insecticide containing hydrazone derivative as the active ingredient and novel hydrazone derivative A insecticide characterized by containing as active ingredient a hydrazone derivative of formula (I) wherein A and Q are an aryl or a heterocyclic group, W is oxygen atom, an aminylene, an alkylene group, an oxya... | 12/26/2006 |
| 7145046 | Production of fluorine compounds Inorganic and organic compounds containing fluorine can be produced, for example, from corresponding chlorine-containing compounds by chlorine/fluorine exchange using fluorinating agents. Monocyclic or bicyclic compounds containing at least two nitrogen atoms, at le... | 12/05/2006 |
| 7129353 | Method for producing 4,6-dichloro-5-fluoropyrimidine The invention relates to a novel process for preparing 4,6-dichloro-5-pyrimidine. ... | 10/31/2006 |
| 7112676 | Pyrimido compounds having antiproliferative activity Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases and are selective against LCK. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tum... | 09/26/2006 |
| 7083832 | Partially fluorinated liquid crystal material The invention provides LC compositions that exhibit V-shaped switching when aligned in an analog device configuration and exhibit bistability when aligned in a bookshelf-type device configuration. The invention more specifically provides LC compositions of formula 1... | 08/01/2006 |
| RE39140 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/20/2006 |
| RE39131 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atoms or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted b... | 06/13/2006 |
| RE39129 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/13/2006 |
| RE39130 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/13/2006 |
| RE39127 | Heterocyclic compounds Novel heterocyclic compounds of the formula wherein, R1 represents a hydrogen atom or an alkyl group, A represents an ethylene group which may be substituted by alkyl or a trimethylene group which may be substituted by... | 06/13/2006 |
| 7045662 | α, α-difluoroamines and difluoromethylene-α, α-diazo compounds The present invention relates to a process for preparing α,α-difluoroamines, difluoromethylene-α,α-diazo compounds and fluorination reagents containing α,α-difluoroamines and/or difluoromethylene-α,α-diazo compounds. ... | 05/16/2006 |
| 7045660 | Compounds as PDE IV and TNF-inhibitors This invention is directed to a [di(ether or thioether)heteroaryl or fluoro substituted aryl] compound or an N-oxide thereof or a pharmaceutically acceptable salt thereof, which is useful for inhibiting the production or physiological effects of TNF in the treatment... | 05/16/2006 |
| RE39056 | 4-Azasteroids for treatment of hyperandrogenic conditions Compounds of structural Formula (I) and pharmacologically acceptable salts and esters thereof possess 5α-reductase inhibitory activity. These compounds inhibit 5α-reductase type 1 and type 2. The compounds of structural Formula... | 04/04/2006 |
| 6984735 | Process for making an aldehyde A process for making an aromatic aldehyde in which a sulfoxide is reacted with a dihalogenated aromatic compound in the absence of an effective amount of an activating reagent. The aldehyde may then be used to make other compounds, such as a compound that acts as a ... | 01/10/2006 |
| 6982331 | Synthesis of chlorinated pyrimidines The invention provides a process for synthesizing chlorinated pyrimidines. The process includes reacting imidoyl chloride compounds with phosgene (COCl2). The imidoyl chloride compounds can be supplied as starting materials or can be produced by reacting ... | 01/03/2006 |
| 6946555 | Preparation of triazoles by organometallic addition to ketones and intermediates therefor The invention provides a process for the preparation of a compound of the formula: or an acid addition or base salt thereof, wherein R is phenyl optionally substitute... | 09/20/2005 |
| 6887875 | 2,5-diarypyrimidine compounds Diarylpyrimidine compounds of Formula I are provided, wherein. or a pharmaceutically acceptable salt thereof, wherein: Ar1 and Ar2 are independently chosen from:... | 05/03/2005 |
| 6844351 | Corticotropin releasing factor antagonists Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R | 01/18/2005 |
| 6822095 | Method for producing 4,6-dichloropyrimidine The present invention relates to a process for preparing 4,6-dichloropyrimidine by reaction of 4-chloro-6-hydroxypyrimidine with an acid chloride. ... | 11/23/2004 |
| 6818631 | Fungicidal pyrimidine derivatives Fungicidal pyrimidine derivatives and the use as a fungicide of the compounds of formula (1): wherein R1 is H, C1-C6alkyl, C2-C6alkenyl, C2-C6 | 11/16/2004 |
| 6809109 | 2, 4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors The present invention relates to 2,4-disubstituted pyridine-N-oxide compounds of formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhib... | 10/26/2004 |
| 6759101 | Liquid crystalline materials containing perfluoroalkyl and alkenyl tail groups Compounds that are useful as components in liquid crystal compositions, particularly in ferroelectric liquid crystal compositions. Compounds of the invention are rod-like molecules with a mesogenic (generally linear) core to which an alkene tail and an alkyl or alko... | 07/06/2004 |
| 6727241 | Anti-inflammatory compositions and methods of use The present invention is directed to pharmaceutical compositions containing active compounds, which inhibit the activity of the chemokines, MIP-1α and RANTES. It also is directed to methods of treating inflammatory and immunoregulatory disorders and diseases using ... | 04/27/2004 |
| 6686469 | Pesticidal pyrimidine-derivatives The invention relates to compounds of the general formula ##STR1## wherein R1 is unsubstituted or mono- to penta-substituted aryl, whereby the substituents are selected from the group consisting for instance of OH, Halogen, CN, C1 -C... | 02/03/2004 |
| 6680385 | Catalytic preparation of aryl methyl ketones using a molecular oxygen-containing gas as the oxidant A method for the preparation of aryl methyl ketones converts a variety of ethyl arenas to the corresponding aryl methyl ketones using a dioxygen-containing gas as the oxidant. The catalyst used for the reaction is a metal complex bearing general formulas ... | 01/20/2004 |
| 6653321 | Naphthylsulfonic acids and related compounds as glucose uptake agonists Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or mixtures of stereoisomers, or their pharmaceutically acceptabl... | 11/25/2003 |
| 6635767 | Synthesis of heteroarylamine intermediate compounds Disclosed are novel 2-(5-halopyridyl) and 2-(5-halopyrimidinyl) magnesium halides, processes of making and their use in the efficient synthesis in their respective 5-halo-2-substituted pyridines and pyrimidines.... | 10/21/2003 |
| 6613909 | Synthesis of heteroarylamine intermediate compounds Disclosed are novel 2-(5-halopyridyl) and 2-(5-halopyrimidinyl) magnesium halides, processes of making and their use in the efficient synthesis in their respective 5-halo-2-substituted pyridines and pyrimidines.... | 09/02/2003 |
| 6600044 | Process for recovery of the desired cis-1,3-oxathiolane nucleosides from their undesired trans-isomers A process for the preparation of 1,3-oxathiolane nucleoside analogues in predominantly the cis-form, from mixture of cis-/trans-1,3-oxathiolane nucleosides or their protected derivatives thereof, comprising: (i) treatment of the cis-/trans-1,3-oxathiolane nucl... | 07/29/2003 |
