Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8093381 | Method of synthesis of fluoroquinolones The invention relates to a method of preparation of fluoroquinolones of formula (I) from compounds of formula (II): in which R1, R2, R3, R4, R5, R6, R7 | 01/10/2012 |
| 7235550 | Polycyclic azaindole compounds The invention relates to compounds of formula (I): wherein: G1 represents an alkylene chain as defined in the description, A represents | 06/26/2007 |
| 6887868 | Therapeutic 5-HT ligand compounds The present invention provides compounds of Formula (I): wherein: R1, R2, R3, R4, R5, R6 R7, R8, n, m, and X have any of the value... | 05/03/2005 |
| 6703371 | Preparations for reducing oxygen consumption during physical efforts The invention relates to pharmaceutically active substances from the group comprising midazolam and compounds with a methyl-substituted nitrogen atom that is the ring atom of a nitrogenous heterocycle. These substances are used to reduce the oxygen consum... | 03/09/2004 |
| 6703401 | Compounds, their preparation and use The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by clear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 03/09/2004 |
| 6699989 | Antiviral and antimicrobial guanidine or biguanidine derivatives Disclosed are guanidine and biguanidine derivatives which have anti-viral and anti-bacterial activity. Also disclosed are pharmaceutical compositions containing such compounds as an active ingredient, and anti-viral and anti-bacterial methods utilizing su... | 03/02/2004 |
| 6624159 | Heterocycle carboxamides as antiviral agents The present invention provides a compound of formula I ##STR1## which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.... | 09/23/2003 |
| 6583138 | Heterocyclic-ring condensed benzothiazine compound The invention provides a novel heterocyclic ring condensed benzothiazine compound which is effective for prevention or remedy of disease, in which histamine, leukotriene and the like participate. The heterocyclic ring condensed benzothiazine compound of t... | 06/24/2003 |
| 6448241 | Thiazolobenzoheterocycles, their preparation and medicaments containing them Compounds of formula (I): ##STR1## their racemates, enantiomers, diastereoisomers and inorganic acid salts and organic acid salts thereof, processes for preparing them and the medicaments containing them are discussed.... | 09/10/2002 |
| 6444812 | Intermediate compounds in the preparation of farnnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N-or C linked imidazoles This invention concerns intermediates in the preparation of compounds of formula ##STR1## the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein the dotted line represents an optional bond; X is o... | 09/03/2002 |
| 6426416 | Anthraquinone and condensed anthraquinone colorants having sulfonamido linked poly (oxyalkylene) moieties and their preparation The process for chemically modifying metal-free, colored anthraquinone or condensed anthraquinone compounds or the compounds prepared by said process for improving one or more properties thereof such as water dispersibility, compatibility with other organ... | 07/30/2002 |
| 6384045 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxypyrone synthetic method is a simple con... | 05/07/2002 |
| 6380235 | Benzimidazolones and analogues The present invention provides compounds and pharmaceutical formulations useful as progesterone receptor agonists and antagonists and having the general formula: ##STR1## wherein: A is O, S, or NR4 ; B is a bond between A and C.dbd.Q, or the mo... | 04/30/2002 |
| 6365586 | Compounds, their preparation and use The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 04/02/2002 |
| 6348460 | 1,2,3-thiadiazole derivatives, plant disease controller and method for using the same A 1,2,3-thiadiazole derivative represented by general formula (I): ##STR1## [wherein R1 is hydrogen atom, halogen atom, (C1 -C6) alkyl, phenyl, etc., R2 is the following group (A) or group (B): ##STR2## (wherein... | 02/19/2002 |
| 6187786 | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles This invention concerns compounds of formula ##STR1## the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein the dotted line represents an optional bond; X is oxygen or sulfur; --A-- is a bivalent ... | 02/13/2001 |
| 6121278 | Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity A compound of formula I: ##STR1## or a pharmaceutically acceptable salt, hydrate, ester, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof, wherein: Y represents the atoms necessary to form a fused 5- to 6-membered, aromatic or non-arom... | 09/19/2000 |
| 6071947 | Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation The present invention relates to substituted (1H-indol-2-yl)-5[(2H-pyrrol-2-ylidene) methyl]-1H-pyrrole compounds and their use as immunomodulating agents, to the preparation of the compounds and to pharmaceutical compositions comprising them.... | 06/06/2000 |
| 6057315 | Antibacterial agents Described are antibacterial agents of formula (I): X is O, S or N--R.sub.8 ; R.sub.1, R.sub.2, R.sub.3 and R.sub.8 are independently H, straight or branched alkyl of 1-6 carbons, cycloalkyl of 3-6 carbons, alkenyl or alkynyl of from 2 to 6 atoms, R hetero... | 05/02/2000 |
| 5998409 | Condensed indole derivatives as 5HT4 -receptor antagonists Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.... | 12/07/1999 |
| 5990122 | Quinolone- and naphthyridonecarboxylic acid derivatives The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compoun... | 11/23/1999 |
| 5985871 | Benzoxazine compounds for enhancing synaptic response Compounds having a certain benzoxazine ring system and their precursors are disclosed which are useful for enhancing synaptic responses mediated by AMPA receptors. Also disclosed are methods for preparing such compounds, and methods for their use in treat... | 11/16/1999 |
| 5958970 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxyprone synthetic method is a simple cond... | 09/28/1999 |
| 5955460 | Oxazolidinone antibacterial agent with tricyclic substituents This invention provides novel oxazolidinone derivatives represented by chemical Formula (I), or pharmaceutically acceptable salts thereof: ##STR1## wherein X is NR1, CR2 R3, O, S, SO, or SO2 ; and Z is NR | 09/21/1999 |
| 5935952 | Quinolone- or naphthylidone-carboxylic acid derivates or their salts This invention relates to a novel quinolone- or naphthyridone-carboxylic acid derivative or its salt useful as an antibacterial agent, said derivative has a substituent represented by the following formula at the 7 position: ##STR1## wherein pre... | 08/10/1999 |
| 5885988 | Benzog!quinoline derivatives The invention provides compounds of formula I ##STR1## wherein X, Y, R1, R2, R3 and R4 are as defined in the description, and a process for preparing them. The compounds of formula I are useful as pharmaceu... | 03/23/1999 |
| 5877313 | Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP Compounds having the following formula I, and pharmaceutically acceptable salts thereof, including dual inhibitors of ACE and NEP and selective ACE inhibitors: ##STR1## wherein: Y1 and Y2 are each independently hydrogen, alkyl, ... | 03/02/1999 |
| 5852014 | Condensed indole derivatives as 5HT4 -receptor antagonists Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.... | 12/22/1998 |
| 5817820 | Quinolone derivatives and processes for the preparation thereof The present invention relates to optical isomers of quinoline compounds of Formula (IA) or Formula (IA'), their pharmaceutically acceptable salts and their intermediates: ##STR1## In the above formulae, A represent nitrogen or ##STR2## in w... | 10/06/1998 |
| 5811548 | Tri-and tetracyclic compounds There are described compounds of the formula ##STR1## Wherein the variables have been defined herein. The compounds are useful as research tools in the determination of biologically active peptides sequences and also potentially suitable as medicamen... | 09/22/1998 |
| 5770597 | Quinolone derivatives and processes for preparing the same The present invention relates to quinoline derivatives substituted in the 7-position by a trans-2,8-diazabicyclo4.3.0!nonan-8-yl group having a broad antibacterial spectrum and to processes for preparing the same.... | 06/23/1998 |
| 5739130 | Heterotricyclic derivatives, process for their preparation and pharmaceutical compositions containing them Heterotricyclic derivatives of the formula: ##STR1## wherein R1 is hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, nitro, amino or protected amino, R2 is hydroxy, protected hydroxy, halogen, amino or protected amino, R... | 04/14/1998 |
| 5731433 | Process for the preparation of rufloxacin and salts thereof A process for the preparation of rufloxacin, a compound of the formula I ##STR1## and salts thereof is described. This is effected by reducing a quinoline disulfide of formula (II) as herein defined, and subjecting the resulting 2-mercaptoethyl quino... | 03/24/1998 |
| 5728693 | Arthropodicidal oxadiazine-thiadiazine-or triazine-carboxanilides Arthropodicidal compounds, compositions and use of compounds having the formula ##STR1##... | 03/17/1998 |
| 5721355 | Method of attaching a fluorescent label to an oligonucleotide Compounds useful to attach a fluorescein label to an oligonucleotide are disclosed. To create these compounds, oxygen groups on the fluorescein moiety are protected (e.g. with acyl groups). One then links a phosphoramidite to the fluorescein moiety via an... | 02/24/1998 |
| 5707988 | Benzod! isoxazole derivatives, compositions containing them and their use in therapy Compounds of formula (I) ##STR1## in which X represents a group >O, >S, >C.dbd.O or >NR wherein R is hydrogen, C1-6 alkyl, phenyl or C7-12 phenalkyl, R1 and R2 each represent hydrogen or together represent ... | 01/13/1998 |
| 5705498 | Piperidine derivatives as 5-HT4 receptor antagonists Compounds of formula (I): ##STR1## wherein Xg is O, S, SO, SO2, CH2, CH, N or NR wherein R is hydrogen or C1-6 alkyl; A is a saturated or unsaturated polymethylene chain of 2-4 carbon atoms; R1g | 01/06/1998 |
| 5703233 | Quinilone disulfide as intermediates A process for preparing rufloxacin using a compound of the formula I ##STR1## as a starting material is described, where R is herein defined.... | 12/30/1997 |
| 5690906 | Dopamine D-3 and serotonin (5-HT1A) receptor ligands and imaging agents Tetralin derivatives, such as 7-hydroxy-2-(N-n-propyl-N-3 '-iodo-2'-propenyl)-amino!tetralin and 8-hydroxy-2-(N-n-propyl-N-3 '-iodo-2'-propenyl)amino-tetralin, are disclosed which have affinity and specificity for dopamine D-3 and/or serotonin 5-HT1A... | 11/25/1997 |
| 5688791 | Aryl group-or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-hiv agent Disclosed are an aryl group- or heterocyclic group-substituted aminoquinolone compound represented by the formula (Ia), (Ib) or (Ic): ##STR1## wherein each of the substitutents are defined in the specification, or a salt of the compound, and an AIDS ... | 11/18/1997 |
