Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 4052398 | Diazarhodamine-lactones, their manufacture and their use as dye intermediates for copying processes New diazarhodamine-lactones of the formula ##STR1## where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms, unsubstituted phenyl or phenyl substituted by one or two alkyls of 1 to 3 carbon atoms... | 10/04/1977 |
| 4051244 | 2,4-Diamino 5-bromo 6-chloro pyrimidines, process for their preparation and use as pharmaceuticals Compounds of the general formula ##STR1## wherein R1 and R3 represent hydrogen or alkyl containing 1 to 4 carbons; R2 and R4 represent hydrogen, alkyl containing 1 to 8 carbons, dialkylaminoalkyl or aryl, ... | 09/27/1977 |
| 4051242 | Substituted N-acyl-N"-(3-amino-2-cyanoacryloyl-)formamidrazones Therapeutically-active and pharmacologically-acceptable N-acyl-N" -(3-amino-2-cyanoacryloyl)-formamidrazones and their pharmaceutically-acceptable acid-addition salts inhibit xanthine oxidase and are useful as the active ingredient in medicaments for the ... | 09/27/1977 |
| 4042577 | Azo dyes having one or two triazinyl-or pyrimidyl-acetic acid ester or amide coupling component radicals Compounds of the formula ##STR1## in which R1 signifies a group of the formula --NH2, --NH--R4 or --O--R4, in which R4 signifies a (C1-8)alkyl radical, a (C5-8)cycloalkyl ra... | 08/16/1977 |
| 4038392 | 3-(Heterocyclicthiomethyl) quinoxaline-1,4-dioxides 2-Substituted-3-thiomethylheterocyclic-quinoxaline-1,4-dioxides are prepared from 2-substituted-3-bromomethyl-quinoxaline-1,4-dioxides and heterocyclic thiols. Oxidations yield the corresponding sulfoxides and sulfones. These compounds are effective in tr... | 07/26/1977 |
| 4038279 | N-aryl-N'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof Compounds of the formula ##STR1## wherein R is phenyl; phenyl having one or two substituents attached thereto, said substituents being selected from the group consisting of alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, alkylthio of ... | 07/26/1977 |
| 4026884 | Methyne dyes and photographic elements Novel methyne dyes comprising two auxochromic groups of the type used in a cyanine or merocyanine dye linked by a carbon atom chain wherein each of the carbon atoms have an unsaturated linkage to at least one adjacent carbon atom in the chain and at least... | 05/31/1977 |
| 4022770 | Metal complexes of azomethines and process for their manufacture Metal complexes of azomethines of the formula ##STR1## are useful for coloring plastics and lacquers in yellow to red shades of excellent fastness properties.... | 05/10/1977 |
| 4011218 | 1,2,4-Triazoles Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agen... | 03/08/1977 |
| 4001411 | 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof 2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthe... | 01/04/1977 |
| 3998827 | 6-Amino-4-(substituted piperidino)-1,2-dihydro-1-hydroxy-2-iminopyrimidines 6-Amino-1,2-dihydro-1-hydroxy-2-iminopyrimidines, their carboxyacylated counterparts, and the corresponding acid addition salts thereof are disclosed. These compounds, useful inter alia as antihypertensive agents, are substituted in the 4-position and opt... | 12/21/1976 |
| 3980781 | Fungicidal composition and method containing 2-amino-pyrimidines Fungicidal pyrimidine derivatives and the use thereof in combatting plant diseases. Representative derivatives are 2-dimethylamino-4-methyl-5-n-pentyl-6-hydroxypyrimidine and 2-dimethylamino-4-methyl-5-n-propyl-6-hydroxypyrimidine.... | 09/14/1976 |
| 3975384 | 2,4,5,6-Tetrasubstituted pyrimidines and salts thereof Compounds of the formula ##SPC1## Wherein R1 is alkoxy of 1 to 3 carbon atoms, morpholino, thiomorpholino, 1-oxido-thiomorpholino, 1,1-dioxido-thiomorpholino, or ##EQU1## where A is hydrogen, alkanoyl of 1 to 4 carbon atoms, alkenoyl of 2 ... | 08/17/1976 |
| 3968227 | Guanidino, thioureido and isothioureido derivatives containing imidazole groups The compounds are C2 -C8 straight chain alkanes terminally substituted, symmetrically or unsymmetrically, by N-(N'-substituted guanidino), N-(N',N" -disubstituted guanidino), N-(N'-substituted thioureido), N-(nitromethylene amidino) ... | 07/06/1976 |
| 3959283 | Amino-derivatives of 1,4-benzodioxan 1-[2-(1,4-Benzodioxanyl)methyl]-4-(2-hydroxyethyl)-piperazine hemifumarate and the related compounds of formula: ##SPC1## In which R is hydrogen or alkyl; and A is --CH(CH3)COOC2 H5, --CH2 CH2 O(C | 05/25/1976 |
| 3957786 | Aryl-substituted piperazinyl-alkylamino-uracils, -uracil ethers and -uracil thioethers and method for their production Aryl-substituted piperazinyl-alkylamino-uracils, the corresponding uracil ethers and uracil-thioethers and their pharmaceutically acceptable salts such as the hydrochloride, and method for the preparation of these compounds. The novel compounds are useful... | 05/18/1976 |
| 3956325 | 5-Heterocyclic-1,2,3,6-tetrahydro-4(5H) pyrimidinone The compounds of this invention are 5-heterocyclic-1,2,3,6-tetrahydro-4(5H)-pyrimidinethiones which have pharmacological activity, in particular gastric acid secretion inhibitory activity, and 5-heterocyclic-1,2,3,6-tetrahydro-4(5H)-pyrimidinones which ... | 05/11/1976 |
| 3954764 | Dibenzo [b,f]thiepins bearing piperazinyl substitution Compounds of the formulas ##SPC1## Wherein R1, R2, R3, R4, R5, R6, m and n and X are as hereinafter set forth, Are described. The compounds of formulas I and Ia are useful as neuroleptic ag... | 05/04/1976 |
| 3948892 | 2-Alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides The compounds are 2-alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides, for example 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide, which are inhibitors of gastric acid secretion.... | 04/06/1976 |
| 3944551 | N-Coumaranyl and chromanyl -methyl-or sulfur analogs thereof-N'- thiazolyl piperazines Disubstituted piperazines of the formula: ##SPC1## Wherein: n is 1 or 2; X is oxygen or sulfur; R is hydrogen or lower alkyl; Het is pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, quinolyl, quinazolyl, thiazolyl or benzothiazolyl, each optionally substituted by... | 03/16/1976 |
| 3944549 | Amino derivatives of 1,4-benzodioxan 1-[2-(1,4-benzodioxanyl)methyl]-4-(2-hydroxyethyl)-piperazine hemifumarate and the related compounds of formula: ##SPC1## In which R is hydrogen or alkyl; and A is --Z--OR1, --CH2 CHOR"1 CH2 OR'1, --Z... | 03/16/1976 |
| 3941789 | N-Aryl-N'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof Compounds of the formula ##EQU1## wherein R is phenyl; phenyl having one or more substituents attached thereto, said substituents being selected from the group consisting of alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, alkylthio of ... | 03/02/1976 |
| 3940394 | 2-PYRIMIDINYLTHIO)ALKANOIC ACIDS, ESTERS, AMIDES AND HYDRAZIDES (2-Pyrimidinylthio)alkanoic acid, esters, amides and hydrazides as well as various 4- and 6-substituted derivatives thereof as depicted by the structural formula: ##SPC1## In which R and R2 are independently --H or lower alkyl; R1 is... | 02/24/1976 |
| 3940398 | 2-[[4-(Azine or diazine or triazine)-1-piperazinyl]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones Compounds of the following formula and their acid addition salts ##SPC1## Wherein R1 and R2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is ... | 02/24/1976 |
| 3940395 | 4-Amino-2-phenyl-6-thiopryimidines The invention is directed to 4-amino-2-phenyl-6-thiopyrimidine compounds having the formula ##SPC1## Where R1 -R3 are as defined in the specification. The compounds have pharmacodynamic activity as central nervous system depressants.... | 02/24/1976 |
